SG46218A1 - Substituted biphenyl sulfonamide endothelin antagonists - Google Patents

Substituted biphenyl sulfonamide endothelin antagonists

Info

Publication number: SG46218A1
Authority: SG; Singapore
Prior art keywords: substituted biphenyl; endothelin antagonists; biphenyl sulfonamide; sulfonamide endothelin; antagonists
Prior art date: 1995-02-06

Application number

SG1996000999A

Other languages

English (en)

Inventor

Natesan Murugesan

Philip D Stein

Joel C Barrish

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-06

Filing date

1996-02-06

Publication date

1998-02-20

1995-02-06 Priority claimed from US08/384,066 external-priority patent/US5760038A/en

1996-01-26 Priority to CA002168154A priority Critical patent/CA2168154A1/en

1996-01-26 Priority to IL11691696A priority patent/IL116916A/xx

1996-01-31 Priority to CZ96292A priority patent/CZ29296A3/cs

1996-02-05 Priority to NO960473A priority patent/NO305559B1/no

1996-02-05 Priority to FI960516A priority patent/FI960516L/fi

1996-02-05 Priority to HU9600256A priority patent/HUP9600256A3/hu

1996-02-06 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1996-02-06 Priority to SG1996000999A priority patent/SG46218A1/en

1996-02-06 Priority to JP8019792A priority patent/JPH08245600A/ja

1996-02-06 Priority to EP96101685A priority patent/EP0725067A1/en

1996-02-06 Priority to PL96312650A priority patent/PL183283B1/pl

1996-02-06 Priority to CN96102541A priority patent/CN1060172C/zh

1998-02-20 Publication of SG46218A1 publication Critical patent/SG46218A1/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

SG1996000999A 1995-02-06 1996-02-06 Substituted biphenyl sulfonamide endothelin antagonists SG46218A1 (en)

Priority Applications (11)

Application Number	Priority Date	Filing Date	Title
CA002168154A CA2168154A1 (en)	1995-02-06	1996-01-26	Substituted biphenyl sulfonamide endothelin antagonists
IL11691696A IL116916A (en)	1995-02-06	1996-01-26	Substituted biphenyl sulfonamide derivatives and pharmaceutical compositions containing the same
CZ96292A CZ29296A3 (en)	1995-02-06	1996-01-31	Substituted biphenylsulfonamide derivatives as endothelial antagonists
HU9600256A HUP9600256A3 (en)	1995-02-06	1996-02-05	Substituted diphenyl-sulfonamide endothelin antagonists, pharmaceutical compositions containing the same and their medical uses
FI960516A FI960516L (fi)	1995-02-06	1996-02-05	Substituoituja bifenyylisulfonamidiendoteliiniantagonisteja
NO960473A NO305559B1 (no)	1995-02-06	1996-02-05	Substituerte bifenyl-sulfonamid-endotelin-antagonister
SG1996000999A SG46218A1 (en)	1995-02-06	1996-02-06	Substituted biphenyl sulfonamide endothelin antagonists
JP8019792A JPH08245600A (ja)	1995-02-06	1996-02-06	置換ビフェニルスルホンアミドエンドセリン拮抗剤
EP96101685A EP0725067A1 (en)	1995-02-06	1996-02-06	Substituted biphenyl sulfonamide endothelin antagonists
PL96312650A PL183283B1 (pl)	1995-02-06	1996-02-06	Nowe podstawione bifenyloizoksazolosulfonamidy i środek farmaceutyczny
CN96102541A CN1060172C (zh)	1995-02-06	1996-02-06	取代的联苯磺酰胺类内皮素拮抗剂

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/384,066 US5760038A (en)	1995-02-06	1995-02-06	Substituted biphenyl sulfonamide endothelin antagonists
SG1996000999A SG46218A1 (en)	1995-02-06	1996-02-06	Substituted biphenyl sulfonamide endothelin antagonists

Publications (1)

Publication Number	Publication Date
SG46218A1 true SG46218A1 (en)	1998-02-20

Family

ID=26665074

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG1996000999A SG46218A1 (en)	1995-02-06	1996-02-06	Substituted biphenyl sulfonamide endothelin antagonists

Country Status (11)

Country	Link
EP (1)	EP0725067A1 (pl)
JP (1)	JPH08245600A (pl)
CN (1)	CN1060172C (pl)
CA (1)	CA2168154A1 (pl)
CZ (1)	CZ29296A3 (pl)
FI (1)	FI960516L (pl)
HU (1)	HUP9600256A3 (pl)
IL (1)	IL116916A (pl)
NO (1)	NO305559B1 (pl)
PL (1)	PL183283B1 (pl)
SG (1)	SG46218A1 (pl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5962490A (en)	1987-09-25	1999-10-05	Texas Biotechnology Corporation	Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
US6342610B2 (en)	1993-05-20	2002-01-29	Texas Biotechnology Corp.	N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
US6541498B2 (en)	1993-05-20	2003-04-01	Texas Biotechnology	Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US6613804B2 (en)	1993-05-20	2003-09-02	Encysive Pharmaceuticals, Inc.	Biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin
US6376523B1 (en)	1994-05-20	2002-04-23	Texas Biotechnology Corporation	Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US6030991A (en) *	1993-05-20	2000-02-29	Texas Biotechnology Corp.	Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US5612359A (en) *	1994-08-26	1997-03-18	Bristol-Myers Squibb Company	Substituted biphenyl isoxazole sulfonamides
EP0819125B1 (en) *	1995-04-04	2003-06-18	Texas Biotechnology Corporation	Thienyl-, furyl-, pyrrolyl- and biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin
US5846990A (en) *	1995-07-24	1998-12-08	Bristol-Myers Squibb Co.	Substituted biphenyl isoxazole sulfonamides
JPH09124620A (ja) *	1995-10-11	1997-05-13	Bristol Myers Squibb Co	置換ビフェニルスルホンアミドエンドセリン拮抗剤
AU717230B2 (en)	1996-02-20	2000-03-23	Bristol-Myers Squibb Company	Methods for the preparation of biphenyl isoxazole sulfonamides
US5856507A (en) *	1997-01-21	1999-01-05	Bristol-Myers Squibb Co.	Methods for the preparation of biphenyl isoxazole sulfonamides
US5939446A (en) *	1996-04-09	1999-08-17	Bristol-Myers Squibb Co.	Heteroaryl substituted phenyl isoxazole sulfonamide endothelin antagonists
US5804585A (en) *	1996-04-15	1998-09-08	Texas Biotechnology Corporation	Thieno-pyridine sulfonamides derivatives thereof and related compounds that modulate the activity of endothelin
WO1998033781A1 (en) *	1997-01-30	1998-08-06	Bristol-Myers Squibb Company	Method for preventing or treating low renin hypertension by administering an endothelin antagonist
TW536540B (en) *	1997-01-30	2003-06-11	Bristol Myers Squibb Co	Endothelin antagonists: N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide and N-(4,5-dimethyl-3-isoxazolyl)-2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl)methyl]-4'-(2-oxazolyl)[1,1'-biphe
US6030975A (en) *	1997-03-14	2000-02-29	Basf Aktiengesellschaft	Carboxylic acid derivatives, their preparation and use in treating cancer
US5783705A (en)	1997-04-28	1998-07-21	Texas Biotechnology Corporation	Process of preparing alkali metal salys of hydrophobic sulfonamides
TR200202738T2 (tr)	1997-04-28	2003-03-21	Texas Biotechnology Corporation	Endotelin ile ilgili hastalıkların tedavisinde kullanılan sülfanoamidler
CA2326427A1 (en) *	1998-03-31	1999-10-07	Koichiro Yamada	Preventives/remedies for urinary disorder
ID26984A (id) *	1998-07-06	2001-02-22	Bristol Myers Squibb Co	Senyawa-senyawa sulfonamida sebagai antagonis reseptor angiotensin endotelin ganda
CA2367916A1 (en)	1999-03-19	2000-09-28	Ambarish Singh	Methods for the preparation of biphenyl isoxazole sulfonamides
US6455554B1 (en)	1999-06-07	2002-09-24	Targacept, Inc.	Oxopyridinyl pharmaceutical compositions and methods for use
US6639082B2 (en)	2000-10-17	2003-10-28	Bristol-Myers Squibb Company	Methods for the preparation of biphenyl isoxazole sulfonamides
JP6139272B2 (ja) *	2012-06-01	2017-05-31	株式会社半導体エネルギー研究所	発光素子の作製方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5591761A (en) *	1993-05-20	1997-01-07	Texas Biotechnology Corporation	Thiophenyl-, furyl-and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
NZ247440A (en) *	1992-05-06	1995-04-27	Squibb & Sons Inc	Phenyl sulphonamide derivatives, preparation and pharmaceutical compositions thereof

1996
- 1996-01-26 IL IL11691696A patent/IL116916A/xx not_active IP Right Cessation
- 1996-01-26 CA CA002168154A patent/CA2168154A1/en not_active Abandoned
- 1996-01-31 CZ CZ96292A patent/CZ29296A3/cs unknown
- 1996-02-05 NO NO960473A patent/NO305559B1/no not_active IP Right Cessation
- 1996-02-05 HU HU9600256A patent/HUP9600256A3/hu unknown
- 1996-02-05 FI FI960516A patent/FI960516L/fi unknown
- 1996-02-06 SG SG1996000999A patent/SG46218A1/en unknown
- 1996-02-06 PL PL96312650A patent/PL183283B1/pl unknown
- 1996-02-06 EP EP96101685A patent/EP0725067A1/en not_active Withdrawn
- 1996-02-06 JP JP8019792A patent/JPH08245600A/ja active Pending
- 1996-02-06 CN CN96102541A patent/CN1060172C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
PL312650A1 (en)	1996-08-19
HU9600256D0 (en)	1996-03-28
FI960516A7 (fi)	1996-08-07
PL183283B1 (pl)	2002-06-28
CN1138581A (zh)	1996-12-25
IL116916A0 (en)	1996-05-14
NO305559B1 (no)	1999-06-21
CZ29296A3 (en)	1996-09-11
NO960473L (no)	1996-08-07
CN1060172C (zh)	2001-01-03
JPH08245600A (ja)	1996-09-24
HUP9600256A3 (en)	1998-08-28
EP0725067A1 (en)	1996-08-07
NO960473D0 (no)	1996-02-05
IL116916A (en)	2000-09-28
CA2168154A1 (en)	1996-08-07
FI960516A0 (fi)	1996-02-05
FI960516L (fi)	1996-08-07
HUP9600256A2 (en)	1997-10-28

Publication	Publication Date	Title
AU680522B2 (en)	1997-07-31	Sulfonamide endothelin antagonists
AU4331496A (en)	1996-08-15	Substituted biphenyl sulfonamide endothelin antagonists
AU6810596A (en)	1997-04-17	Substituted biphenylsulfonamide endothelin antagonists
ZA948541B (en)	1995-05-02	Endothelin receptor antagonists
EP0763035A4 (en)	1997-10-01	ENDOTHELIN RECEPTOR ANTAGONISTS
AU3661397A (en)	1998-02-20	Substituted biphenyl sulfonamide endothelin antagonists
HU9600256D0 (en)	1996-03-28	Substituted diphenyl-sulfonamides, antagonists of endothelin
SG49667A1 (en)	1998-06-15	Endothelin receptor antagonists
HU9601176D0 (en)	1996-06-28	Adhesion-receptor antagonists
IL134175A0 (en)	2001-04-30	Endothelin antagonists
EP0766684A4 (en)	1997-07-16	ENDOTHELINE RECEPTOR ANTAGONISTS
HU9602054D0 (en)	1996-09-30	Endothelin receptor antagonists
HUP9902817A3 (en)	2001-03-28	Endothelin receptor antagonists
EP0854721A4 (en)	1998-12-02	ENDOTHELIN RECEPTOR ANTAGONISTS
EP0841926A4 (en)	1999-08-04	ENDOTHELIN RECEPTOR ANTAGONISTS
AU6079296A (en)	1997-02-06	Endothelin receptor antagonists
EP0768878A4 (en)	1999-02-17	ENDOTHELINE RECEPTOR ANTAGONISTS
ZA985209B (en)	1999-01-06	Endothelin antagonists
AU6200296A (en)	1997-02-20	Endothelin receptor antagonists
ZA965754B (en)	1997-01-27	Butenolide endothelin antagonists
EP0841916A4 (en)	2001-04-11	ENDOTHELINE RECEPTOR ANTAGONISTS
AU6826698A (en)	1998-10-12	Endothelin receptor antagonists
EP0711157A4 (en)	1996-07-31	ENDOTHELIN RECEPTOR ANTAGONISTS
AU3856295A (en)	1996-06-06	Endothelin antagonists
EP0868180A4 (en)	1999-08-04	ENDOTHELINM RECEPTOR ANTOGONISTS