SG49631A1 - Hepatitis b vaccine - Google Patents

Hepatitis b vaccine

Info

Publication number: SG49631A1
Authority: SG; Singapore
Prior art keywords: pct; mhbsag; fragment; sec; vaccine
Prior art date: 1994-02-02

Application number

SG1996001902A

Other languages

English (en)

Inventor

Peter Karayiannis

Howard Christopher Thomas

Original Assignee

Imperial College

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-02-02

Filing date

1995-02-02

Publication date

1998-06-15

1995-02-02 Application filed by Imperial College filed Critical Imperial College

1998-06-15 Publication of SG49631A1 publication Critical patent/SG49631A1/en

Links

SPSXSWRZQFPVTJ-ZQQKUFEYSA-N hepatitis b vaccine Chemical compound C([C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCSC)C(=O)N[C@@H](CC1N=CN=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)OC(=O)CNC(=O)CNC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H](N)CCCNC(N)=N)C1=CC=CC=C1 SPSXSWRZQFPVTJ-ZQQKUFEYSA-N 0.000 title 1
229940124736 hepatitis-B vaccine Drugs 0.000 title 1
239000012634 fragment Substances 0.000 abstract 2
241000700721 Hepatitis B virus Species 0.000 abstract 1
102000008300 Mutant Proteins Human genes 0.000 abstract 1
108010021466 Mutant Proteins Proteins 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
238000001514 detection method Methods 0.000 abstract 1
238000000338 in vitro Methods 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
229960005486 vaccine Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/826—Viruses

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Public Health (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Gastroenterology & Hepatology (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)

SG1996001902A 1994-02-02 1995-02-02 Hepatitis b vaccine SG49631A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB9401987A GB9401987D0 (en)	1994-02-02	1994-02-02	Modified nucleic acid

Publications (1)

Publication Number	Publication Date
SG49631A1 true SG49631A1 (en)	1998-06-15

Family

ID=10749735

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG1996001902A SG49631A1 (en)	1994-02-02	1995-02-02	Hepatitis b vaccine

Country Status (16)

Country	Link
US (1)	US5856084A (de)
EP (1)	EP0741745B1 (de)
JP (1)	JP3812949B2 (de)
KR (1)	KR100370341B1 (de)
CN (1)	CN1057774C (de)
AT (1)	ATE310014T1 (de)
AU (1)	AU693154B2 (de)
CA (1)	CA2182375A1 (de)
DE (1)	DE69534617T2 (de)
ES (1)	ES2258767T3 (de)
GB (1)	GB9401987D0 (de)
MX (1)	MX9603182A (de)
NZ (1)	NZ278937A (de)
PL (1)	PL315784A1 (de)
SG (1)	SG49631A1 (de)
WO (1)	WO1995021189A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5595739A (en) *	1993-05-07	1997-01-21	Abbott Laboratories	Hepatitis B virus mutants, reagents and methods for detection
GB9608626D0 (en) *	1996-04-25	1996-07-03	Univ College Of London	Hepatitis b monoclonal antibodies
EP0919568A1 (de)	1997-12-01	1999-06-02	Sorin Diagnostics S.r.l.	Fluchtmutanten des Oberflächenantigens des Hepatitis B Virus
US6787142B2 (en)	2001-04-30	2004-09-07	Government Of Republic Of Singapore	Mutant human hepatitis B viral strain and uses thereof
TR200003778T2 (tr)	1998-06-19	2001-06-21	Government Of The Republic Of Singapore	Aşıyla indüklenen hepatit B viral kültürü ve kullanım yerleri
NZ508890A (en) *	1998-06-19	2004-04-30	Government Of The Republic Of Singapore	A mutant human hepatitis B viral strain and used thereof
FR2803599B1 (fr) *	2000-01-06	2004-11-19	Inst Nat Sante Rech Med	Nouveau virus mute de l'hepatite b, ses constituants nucleiques et proteiques et leurs applications
KR100368756B1 (ko) *	2000-02-01	2003-01-24	주식회사 엘지생명과학	비형 간염 표면 항원에 대한 항체 진단 시약의 제조방법,이를 이용하여 수득되는 비형 간염 항원에 대한 항체 진단시약 및 비형 간염 바이러스 항체 진단 시약
CA2486420C (en) *	2002-06-14	2014-04-15	Gen-Probe Incorporated	Compositions and methods for detecting hepatitis b virus
CN100355777C (zh) *	2003-02-10	2007-12-19	文洪模	乙型肝炎病毒pre－S突变蛋白及其制备方法与应用
ES2385481T3 (es) *	2003-06-20	2012-07-25	Siemens Healthcare Diagnostics Products Gmbh	Nueva variante de proteína de superficie (HbsAg) del virus de hepatitis B
ES2428630T3 (es)	2004-09-22	2013-11-08	Advanced Life Science Institute, Inc.	Método para detectar el antígeno s del virus de la hepatitis B
JP4948783B2 (ja) *	2005-05-18	2012-06-06	シスメックス株式会社	抗ＨＢｓモノクローナル抗体
CN100520409C (zh) *	2005-09-06	2009-07-29	珠海丽珠试剂有限公司	新型乙型肝炎病毒表面抗原确认试剂盒
SI3505528T1 (sl)	2011-04-21	2021-04-30	Glaxo Group Limited	Modulacija izražanja virusa hepatitisa B (HBV)
EP2722722A4 (de) *	2011-06-16	2014-04-23	Huawei Tech Co Ltd	Verfahren und vorrichtung zur anzielung einer phasenarrayantenne und phasenarrayantenne
WO2016154593A1 (en)	2015-03-25	2016-09-29	Igm Biosciences, Inc.	Multi-valent hepatitis b virus antigen binding molecules and uses thereof
HRP20241379T1 (hr)	2019-09-30	2024-12-20	Gilead Sciences, Inc.	Cjepiva za hbv i postupci za liječenje hbv

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9007024D0 (en) *	1990-03-29	1990-05-30	Imperial College	Novel vaccine
CA2067003A1 (en) *	1991-04-29	1992-10-30	Peter J. Kniskern	Hbsag escape mutant vaccine
US5595739A (en) *	1993-05-07	1997-01-21	Abbott Laboratories	Hepatitis B virus mutants, reagents and methods for detection

1994
- 1994-02-02 GB GB9401987A patent/GB9401987D0/en active Pending
1995
- 1995-02-02 DE DE69534617T patent/DE69534617T2/de not_active Expired - Fee Related
- 1995-02-02 JP JP52045495A patent/JP3812949B2/ja not_active Expired - Fee Related
- 1995-02-02 AU AU15426/95A patent/AU693154B2/en not_active Ceased
- 1995-02-02 PL PL95315784A patent/PL315784A1/xx unknown
- 1995-02-02 CN CN95191963A patent/CN1057774C/zh not_active Expired - Fee Related
- 1995-02-02 AT AT95907092T patent/ATE310014T1/de not_active IP Right Cessation
- 1995-02-02 CA CA002182375A patent/CA2182375A1/en not_active Abandoned
- 1995-02-02 KR KR1019960704148A patent/KR100370341B1/ko not_active Expired - Fee Related
- 1995-02-02 MX MX9603182A patent/MX9603182A/es not_active IP Right Cessation
- 1995-02-02 WO PCT/GB1995/000208 patent/WO1995021189A1/en not_active Ceased
- 1995-02-02 NZ NZ278937A patent/NZ278937A/en unknown
- 1995-02-02 US US08/500,914 patent/US5856084A/en not_active Expired - Fee Related
- 1995-02-02 ES ES95907092T patent/ES2258767T3/es not_active Expired - Lifetime
- 1995-02-02 SG SG1996001902A patent/SG49631A1/en unknown
- 1995-02-02 EP EP95907092A patent/EP0741745B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0741745B1 (de)	2005-11-16
CN1143373A (zh)	1997-02-19
WO1995021189A1 (en)	1995-08-10
ES2258767T3 (es)	2006-09-01
AU1542695A (en)	1995-08-21
MX9603182A (es)	1997-05-31
NZ278937A (en)	1998-06-26
ATE310014T1 (de)	2005-12-15
EP0741745A1 (de)	1996-11-13
DE69534617T2 (de)	2006-07-20
CA2182375A1 (en)	1995-08-10
JP3812949B2 (ja)	2006-08-23
PL315784A1 (en)	1996-12-09
US5856084A (en)	1999-01-05
CN1057774C (zh)	2000-10-25
JPH09508284A (ja)	1997-08-26
KR100370341B1 (ko)	2003-04-11
GB9401987D0 (en)	1994-03-30
AU693154B2 (en)	1998-06-25
DE69534617D1 (en)	2005-12-22

Publication	Publication Date	Title
DE69534617D1 (en)	2005-12-22	Hepatitis b-impfstoff
NZ237611A (en)	1994-09-27	Variant hepatitis b surface antigen
AU668094B2 (en)	1996-04-26	Seroreactive regions on HPV 16 proteins E1 and E2
IL102687A0 (en)	1993-01-14	Method for enhancing immunogenicity
PT101052A (pt)	1994-01-31	Proteinas hibridas uteis na preparacao de vacinas
IL134392A0 (en)	2001-04-30	Vaccine against hpv
PT81338A (en)	1985-11-01	Antigens particularly envelope antigens of the virus of lymphadenopathies and of the acquired immuno-depressive syndrome and virus process for producing virus envelope antigens in the preparation of immunogenic compositions or for the diagnosis of the presence of antibodies against this virus
EP0571613A4 (en)	1997-03-05	Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
EP0759935A4 (de)	1999-07-07	Rekombinanter papillomavirus l1
WO1994006913A3 (en)	1994-06-09	Recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines
WO2002032923A3 (en)	2002-08-01	Improved formulations using heat shock/stress protein-peptide complexes
EP1326895B8 (de)	2006-06-21	Monoklonale antikörper gegen hepatitis b virus
NZ295056A (en)	1999-06-29	Hepatitis virus e strain, recombinant proteins thereof, use in diagnostic methods and vaccines
GR3024670T3 (en)	1997-12-31	Induction of protection against viral infection
CA2286399A1 (en)	1998-10-22	Recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines
GB2299994A (en)	1996-10-23	Equine arteritis virus peptides antibodies and their use in a diagnostic test
WO2002051865A3 (fr)	2002-09-12	Antigenes proteiques inducteurs d'anticorps neutralisant le virus vih
NZ532271A (en)	2006-03-31	Peptide mimics of conserved gonococcal epitopes and methods and compositions using them
GR3036125T3 (en)	2001-09-28	Recombinant proteins having the immunoreactivity of Hepatitis B virus e antigens (HBeAg), method for their production and their application in immunoassays and as vaccines.
NZ334582A (en)	2000-07-28	Polyprotein construct of a papillomavirus
TH14110A (th)	1994-06-22	เพพไทด์
US20080075717A1 (en)	2008-03-27	Antigen Imitating Extracellular Areas of Membrane Proteins of Type III Produced from Intracellular Pathogenic Micro-Organisms, Derived Conformational Antibodies and the Use Thereof