SG50563A1 - New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents - Google Patents

New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents

Info

Publication number
SG50563A1
SG50563A1 SG1996005012A SG1996005012A SG50563A1 SG 50563 A1 SG50563 A1 SG 50563A1 SG 1996005012 A SG1996005012 A SG 1996005012A SG 1996005012 A SG1996005012 A SG 1996005012A SG 50563 A1 SG50563 A1 SG 50563A1
Authority
SG
Singapore
Prior art keywords
hepatitis
therapeutic
diagnostic agents
new sequences
present
Prior art date
Application number
SG1996005012A
Other languages
English (en)
Inventor
Geert Maertens
Lieven Stuyver
Original Assignee
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innogenetics Nv filed Critical Innogenetics Nv
Publication of SG50563A1 publication Critical patent/SG50563A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG1996005012A 1993-04-27 1994-04-27 New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents SG50563A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93401099 1993-04-27
EP93402019 1993-08-05

Publications (1)

Publication Number Publication Date
SG50563A1 true SG50563A1 (en) 1998-07-20

Family

ID=26134679

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996005012A SG50563A1 (en) 1993-04-27 1994-04-27 New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents

Country Status (15)

Country Link
US (3) US6762024B2 (fr)
EP (4) EP0651807B1 (fr)
JP (5) JPH07508423A (fr)
CN (1) CN1108030A (fr)
AT (4) ATE552340T1 (fr)
AU (1) AU688323B2 (fr)
BR (1) BR9405334A (fr)
CA (2) CA2662090A1 (fr)
DE (1) DE69435023T2 (fr)
ES (1) ES2294779T3 (fr)
FI (1) FI946066A7 (fr)
NO (1) NO944967L (fr)
NZ (1) NZ266148A (fr)
SG (1) SG50563A1 (fr)
WO (1) WO1994025601A2 (fr)

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US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US7258977B1 (en) * 1992-11-27 2007-08-21 Innogenetics N.V. Process for typing of HCV isolates
US7255997B1 (en) 1993-04-27 2007-08-14 N.V. Innogenetics S.A. Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
EP0651807B1 (fr) 1993-04-27 2007-09-12 N.V. Innogenetics S.A. Nouvelles sequences de genotypes du virus de l'hepatite c et leur utilisation en tant qu'agents therapeutiques et diagnostiques
ATE281526T1 (de) 1993-05-05 2004-11-15 Common Services Agency Hepatitis-c virus typ 4,5 und 6
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5882852A (en) * 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
WO1996013590A2 (fr) * 1994-10-21 1996-05-09 Innogenetics N.V. Nouvelles sequences de genotypes du virus de l'hepatite c et leur utilisation en tant qu'agents prophylactiques, therapeutiques et diagnostiques
US5851759A (en) * 1996-04-19 1998-12-22 Chiron Corporation Heteroduplex tracking assay (HTA) for genotyping HCV
EP2298900A1 (fr) 1996-09-17 2011-03-23 Novartis Vaccines and Diagnostics, Inc. Compositions et procédés de traitement de maladies intracellulaires
BRPI9909678B8 (pt) 1998-04-17 2021-05-25 Fujirebio Europe N V aperfeiçoados ensaios de imunodiagnóstico usando agentes redutores
DE19980730D2 (de) * 1998-04-28 2001-05-10 Wolfgang Bergter Radioimmunpharmaka zur Therapie der Hepatitis C
US7052830B1 (en) 1998-06-09 2006-05-30 Branch Andrea D Hepatitis C virus peptides and uses thereof
ES2281179T3 (es) * 1998-06-09 2007-09-16 Andrea D. Branch Nuevos peptidos del virus de la hepatitis c y usos de los mismos.
DK1354204T4 (da) * 2000-06-15 2010-06-14 Novartis Vaccines & Diagnostic HCV-antigen/antistof-kombinationssay
US7022830B2 (en) * 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
RU2286172C2 (ru) * 2000-08-17 2006-10-27 Трипеп Аб Вакцины, содержащие рибавирин, и способы их использования
US6680059B2 (en) * 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
JP5175417B2 (ja) * 2000-08-17 2013-04-03 トリペップ アクチ ボラゲット リバビリンを含むワクチンおよびその使用方法
US7196183B2 (en) * 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
MD2149G2 (ro) * 2001-11-23 2003-10-31 Институт Генетики И Физиологии Растений Академии Наук Молдовы Primer oligonucleotidic pentru depistarea ARN-ului virusului hepatitei C
ES2346717T3 (es) * 2002-03-11 2010-10-19 Lab 21 Limited Metodo y composiciones para identificar y caracterizar la hepatitis c.
CA2484941A1 (fr) 2002-07-24 2004-02-05 Intercell Ag Antigenes a phase de lecture alternante a partir de virus
EP2402026A3 (fr) 2002-09-13 2012-04-18 Intercell AG Procédé pour isoler des peptides du virus de l'hépatite C
ATE485056T1 (de) 2003-03-24 2010-11-15 Intercell Ag Verbesserte impfstoffe
CN1822856B (zh) 2003-07-11 2010-04-28 英特塞尔股份公司 Hcv疫苗
ES2596753T3 (es) 2003-08-29 2017-01-11 Fujirebio Europe N.V. Nuevo clado del virus de la hepatitis C y secuencias prototipo del mismo
WO2005067643A2 (fr) 2004-01-07 2005-07-28 Third Wave Technologies, Inc. Determination d'un genotype du virus de l'hepatite c
US20060162667A1 (en) * 2005-01-26 2006-07-27 Papadoyianis Ernest D Aquatic habitat and ecological tank
CA2618429A1 (fr) * 2005-05-25 2007-03-22 Tripep Ab Gene de fusion ns3/4a non structurel de l'hepatite c
US20070072211A1 (en) 2005-06-30 2007-03-29 Roche Molecular Systems, Inc. Asymmetric PCR coupled with post-PCR characterization for the identification of nucleic acids
MD3300G2 (ro) * 2006-09-28 2007-11-30 Институт Генетики, Физиологии И Защиты Растений Академии Наук Молдовы Primer oligonucleotidic pentru depistarea ARN-ului virusului hepatitei C
EP2121991A2 (fr) 2006-10-20 2009-11-25 Innogenetics N.V. Méthode d'analyse des mutations
EP2121990A2 (fr) * 2006-10-20 2009-11-25 Innogenetics N.V. Méthode d'analyse des variations de séquence dans la zone génomique ns5b du vhc
EP2463389A1 (fr) 2006-10-20 2012-06-13 Innogenetics N.V. Méthode d'analyse des variations de séquence dans la zone génomique NS5B du VHC
EA018102B1 (ru) * 2007-08-09 2013-05-30 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Способ идентификации генотипа и подтипа вируса гепатита c на биологическом микрочипе
US20090214593A1 (en) * 2007-08-16 2009-08-27 Tripep Ab Immunogen platform
EP2185195A2 (fr) * 2007-08-16 2010-05-19 Tripep Ab Plate-forme immunogène
WO2009059021A2 (fr) * 2007-10-30 2009-05-07 Intermune, Inc. Génotypage et phénotypage du vhc
EP2414839B1 (fr) * 2009-03-30 2014-06-25 Biomérieux Support solide de détection du vhc
WO2013150450A1 (fr) * 2012-04-02 2013-10-10 Universidade Do Porto Fragments homologues du vhc, lignées cellulaires et applications associées
WO2016160046A1 (fr) * 2015-03-27 2016-10-06 Ortho-Clinical Diagnostics, Inc. Polypeptides ns4a/ns3 modifié du vhc et leurs utilisations
ES3008759T3 (en) * 2016-08-02 2025-03-25 Hoffmann La Roche Helper oligonucleotide for improving efficiency of amplification and detection/quantitation of nucleic acids

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EP0651807B1 (fr) 1993-04-27 2007-09-12 N.V. Innogenetics S.A. Nouvelles sequences de genotypes du virus de l'hepatite c et leur utilisation en tant qu'agents therapeutiques et diagnostiques
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JPH06319563A (ja) 1993-05-13 1994-11-22 Imuno Japan:Kk Ｃ型肝炎ウイルス遺伝子、オリゴヌクレオチド、並びにｃ型 肝炎ウイルス遺伝子型判定方法
US5882852A (en) 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
JP2687852B2 (ja) * 1993-10-13 1997-12-08 日本電気株式会社 半導体メモリ装置

Also Published As

Publication number Publication date
NO944967D0 (no) 1994-12-21
ATE551423T1 (de) 2012-04-15
JP2002233389A (ja) 2002-08-20
CA2662090A1 (fr) 1994-11-10
EP0984067B1 (fr) 2012-04-04
JPH07508423A (ja) 1995-09-21
AU688323B2 (en) 1998-03-12
US20030032005A1 (en) 2003-02-13
JP2004041206A (ja) 2004-02-12
EP1004670B1 (fr) 2012-04-11
EP0651807B1 (fr) 2007-09-12
ATE553201T1 (de) 2012-04-15
US20030008274A1 (en) 2003-01-09
EP0984068A2 (fr) 2000-03-08
ATE373093T1 (de) 2007-09-15
NZ266148A (en) 1997-06-24
EP1004670A2 (fr) 2000-05-31
BR9405334A (pt) 1999-05-25
US7195765B2 (en) 2007-03-27
NO944967L (no) 1994-12-21
FI946066A0 (fi) 1994-12-23
CN1108030A (zh) 1995-09-06
JP2004041207A (ja) 2004-02-12
CA2139100A1 (fr) 1994-11-10
EP0984068A3 (fr) 2000-09-20
WO1994025601A3 (fr) 1995-03-02
DE69435023D1 (de) 2007-10-25
WO1994025601A2 (fr) 1994-11-10
DE69435023T2 (de) 2008-09-11
EP0984067A2 (fr) 2000-03-08
JP2002233388A (ja) 2002-08-20
EP0651807A1 (fr) 1995-05-10
US7157226B1 (en) 2007-01-02
FI946066L (fi) 1994-12-23
EP0984067A3 (fr) 2000-09-27
AU6722294A (en) 1994-11-21
CA2139100C (fr) 2009-06-23
FI946066A7 (fi) 1994-12-23
EP1004670A3 (fr) 2000-09-20
EP0984068B1 (fr) 2012-03-28
ATE552340T1 (de) 2012-04-15
ES2294779T3 (es) 2008-04-01
US6762024B2 (en) 2004-07-13

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