SG52300A1 - Cyclic derivatives pharmaceutical compositions containing these compounds and processes for preparing them - Google Patents

Cyclic derivatives pharmaceutical compositions containing these compounds and processes for preparing them

Info

Publication number: SG52300A1
Authority: SG; Singapore
Prior art keywords: compounds; preparing; processes; pharmaceutical compositions; compositions containing
Prior art date: 1993-02-22

Application number

SG1996002477A

Other languages

English (en)

Inventor

Frank Himmelsbach

Volkhard Austel

Helmut Pieper

Brian Guth

Thomas Muller

Johannes Weisenberger

Gunter Linz

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-02-22

Filing date

1994-02-21

Publication date

1998-09-28

1993-02-22 Priority claimed from DE4305388A external-priority patent/DE4305388A1/de

1994-02-21 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1998-09-28 Publication of SG52300A1 publication Critical patent/SG52300A1/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)
Saccharide Compounds (AREA)

SG1996002477A 1993-02-22 1994-02-21 Cyclic derivatives pharmaceutical compositions containing these compounds and processes for preparing them SG52300A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4305388A DE4305388A1 (de)	1993-02-22	1993-02-22	Cyclische Derivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE4332168A DE4332168A1 (de)	1993-02-22	1993-09-22	Cyclische Derivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number	Publication Date
SG52300A1 true SG52300A1 (en)	1998-09-28

Family

ID=25923309

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG1996002477A SG52300A1 (en)	1993-02-22	1994-02-21	Cyclic derivatives pharmaceutical compositions containing these compounds and processes for preparing them

Country Status (22)

Country	Link
US (3)	US5519036A (cs)
EP (1)	EP0612741B1 (cs)
JP (1)	JP3545446B2 (cs)
KR (1)	KR100322319B1 (cs)
CN (1)	CN1048490C (cs)
AT (1)	ATE167185T1 (cs)
AU (1)	AU673875B2 (cs)
CA (1)	CA2116068A1 (cs)
CZ (1)	CZ37494A3 (cs)
DE (2)	DE4332168A1 (cs)
DK (1)	DK0612741T3 (cs)
ES (1)	ES2118992T3 (cs)
FI (1)	FI940806L (cs)
HU (1)	HU222112B1 (cs)
IL (1)	IL108733A (cs)
MX (1)	MX9401315A (cs)
NO (1)	NO305081B1 (cs)
NZ (1)	NZ250944A (cs)
PH (1)	PH30602A (cs)
PL (1)	PL178215B1 (cs)
SG (1)	SG52300A1 (cs)
UA (1)	UA39099C2 (cs)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19624069A1 (de) *	1996-06-17	1997-12-18	Thomae Gmbh Dr K	Benzazepinderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE4332168A1 (de) *	1993-02-22	1995-03-23	Thomae Gmbh Dr K	Cyclische Derivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5849736A (en) *	1993-11-24	1998-12-15	The Dupont Merck Pharmaceutical Company	Isoxazoline and isoxazole fibrinogen receptor antagonists
DE4424974A1 (de) *	1994-07-15	1996-01-18	Thomae Gmbh Dr K	Harnstoff- und Carbaminsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE4427838A1 (de) *	1994-08-05	1996-02-08	Thomae Gmbh Dr K	Kondensierte Azepinderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE4429079A1 (de) *	1994-08-17	1996-02-22	Thomae Gmbh Dr K	Cyclische Harnstoffderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
BR9510360A (pt) *	1994-12-23	1997-12-23	Thomae Gmbh Dr K	Derivados de piperazina medicamentos contendo esses compostos sua aplicação e processo para sua preparação
ZA963391B (en) *	1995-05-24	1997-10-29	Du Pont Merck Pharma	Isoxazoline fibrinogen receptor antagonists.
US5925635A (en) *	1996-04-17	1999-07-20	Dupont Pharmaceuticals Company	N-(amidinophenyl) cyclourea analogs as factor XA inhibitors
IL123986A (en)	1997-04-24	2011-10-31	Organon Nv	Medicinal compounds
US6262069B1 (en)	1997-08-29	2001-07-17	Protherics Molecular Design Limited	1-amino-7-isoquinoline derivatives as serine protease inhibitors
US6340687B1 (en)	1997-09-03	2002-01-22	American Home Products Corporation	Substituted tetrahydro-pyrimidine-2(1H)-thione HDL-C elevators useful as antiatherosclerotic agents
AU753675B2 (en) *	1998-03-19	2002-10-24	Ajinomoto Co., Inc.	Aminoisoquinoline derivatives
CA2362705A1 (en)	1999-03-19	2000-09-28	Joseph B. Santella, Iii	N-adamant-1-yl-n'-¬4-chlorobenzothiazol-2-yl\| urea useful in the treatment of inflammation and as an anticancer radiosensitizing agent
US6492406B1 (en) *	1999-05-21	2002-12-10	Astrazeneca Ab	Pharmaceutically active compounds
BR0209129A (pt) *	2001-04-18	2005-12-20	Euro Celtique Sa	Compostos, composições farmacêuticas, métodos para tratamento de dores, métodos para modulação de uma resposta farmacológica e usos de compostos
US7291603B2 (en)	2002-07-24	2007-11-06	Ptc Therapeutics, Inc.	Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations
CA2495589A1 (en) *	2002-08-14	2004-02-26	Abbott Laboratories	Azabicyclic compounds are central nervous system active agents
US7135484B2 (en)	2002-08-14	2006-11-14	Abbott Laboratories	Azabicyclic compounds are central nervous system active agents
ATE441417T1 (de)	2002-12-20	2009-09-15	Glaxo Group Ltd	Benzoädüazepinderivate für die behandlung von neurologischen krankheiten
GB0405628D0 (en) *	2004-03-12	2004-04-21	Glaxo Group Ltd	Novel compounds
EP1621535A1 (en) *	2004-07-27	2006-02-01	Aventis Pharma S.A.	Substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
EP1799684B1 (en) *	2004-10-04	2014-12-03	Millennium Pharmaceuticals, Inc.	Lactam compounds useful as protein kinase inhibitors
WO2006117657A1 (en) *	2005-05-03	2006-11-09	Ranbaxy Laboratories Limited	Triazolone derivatives as anti-inflammatory agents
ES2580108T3 (es)	2005-07-11	2016-08-19	Aerie Pharmaceuticals, Inc	Compuestos de isoquinolina
PE20080145A1 (es)	2006-03-21	2008-02-11	Janssen Pharmaceutica Nv	Tetrahidro-pirimidoazepinas como moduladores de trpv1
RU2008150465A (ru)	2006-06-20	2010-07-27	Вайет (Us)	Ингибиторы калиевых каналов подтипа kv1.5
CA2692440A1 (en) *	2006-07-20	2008-01-24	Cascade Therapeutics Inc.	Tetrahydro-5h-pyrido[2,3-d]azepines as 5-ht2c ligands
ES2729424T3 (es) *	2006-09-20	2019-11-04	Aerie Pharmaceuticals Inc	Inhibidores de Rho cinasa
US8455513B2 (en)	2007-01-10	2013-06-04	Aerie Pharmaceuticals, Inc.	6-aminoisoquinoline compounds
WO2009078999A1 (en)	2007-12-17	2009-06-25	Janssen Pharmaceutica N.V.	Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of trpv1
WO2009079765A1 (en) *	2007-12-21	2009-07-02	Cascade Therapeutics Inc.	Compounds with activity at the 5-ht2c receptor
US8455514B2 (en) *	2008-01-17	2013-06-04	Aerie Pharmaceuticals, Inc.	6-and 7-amino isoquinoline compounds and methods for making and using the same
US8450344B2 (en) *	2008-07-25	2013-05-28	Aerie Pharmaceuticals, Inc.	Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
TW201026703A (en) *	2008-12-05	2010-07-16	Millennium Pharm Inc	Thiolactams and uses thereof
EP3828172A1 (en)	2009-05-01	2021-06-02	Aerie Pharmaceuticals, Inc.	Dual mechanism inhibitors for the treatment of disease
MA33451B1 (fr) *	2009-06-26	2012-07-03	Novartis Ag	Dérivés d'imidazolidin-2-one 1,3-disubstitués en tant qu'inhibiteurs de cyp 17
EA023064B1 (ru)	2011-04-28	2016-04-29	Новартис Аг	ИНГИБИТОРЫ 17α-ГИДРОКСИЛАЗЫ/C-ЛИАЗЫ
US20140275160A1 (en)	2013-03-15	2014-09-18	Aerie Pharmaceuticals, Inc.	Combination therapy
US9643927B1 (en)	2015-11-17	2017-05-09	Aerie Pharmaceuticals, Inc.	Process for the preparation of kinase inhibitors and intermediates thereof
JP6832946B2 (ja)	2015-11-17	2021-02-24	アエリエファーマシューティカルズインコーポレイテッド	キナーゼ阻害剤およびその中間体の調製方法
CN109640966A (zh)	2016-08-31	2019-04-16	爱瑞制药公司	眼用组合物
WO2018183911A1 (en)	2017-03-31	2018-10-04	Aerie Pharmaceuticals, Inc.	Aryl cyclopropyl-amino-isoquinolinyl amide compounds
US11427563B2 (en)	2018-09-14	2022-08-30	Aerie Pharmaceuticals, Inc.	Aryl cyclopropyl-amino-isoquinolinyl amide compounds
CA3216456A1 (en) *	2021-05-05	2022-11-10	Diamond Therapeutics Inc.	5-ht2a and/or 5-ht2c receptor agonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9106571D0 (en) *	1991-03-27	1991-05-15	Erba Carlo Spa	Derivatives of substituted imidazol-2-one and process for their preparation
DE4107857A1 (de) *	1991-03-12	1992-09-17	Thomae Gmbh Dr K	Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE4112014A1 (de) *	1991-04-12	1992-10-15	Thomae Gmbh Dr K	Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung
DE4127404A1 (de) *	1991-08-19	1993-02-25	Thomae Gmbh Dr K	Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE4332168A1 (de) *	1993-02-22	1995-03-23	Thomae Gmbh Dr K	Cyclische Derivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
AU675484B2 (en) *	1993-03-24	1997-02-06	Neurosearch A/S	Benzimidazole compounds, their use and preparation

1993
- 1993-09-22 DE DE4332168A patent/DE4332168A1/de not_active Ceased
1994
- 1994-02-21 PL PL94302302A patent/PL178215B1/pl unknown
- 1994-02-21 ES ES94102557T patent/ES2118992T3/es not_active Expired - Lifetime
- 1994-02-21 AU AU56324/94A patent/AU673875B2/en not_active Ceased
- 1994-02-21 FI FI940806A patent/FI940806L/fi unknown
- 1994-02-21 CA CA002116068A patent/CA2116068A1/en not_active Abandoned
- 1994-02-21 JP JP02272794A patent/JP3545446B2/ja not_active Expired - Fee Related
- 1994-02-21 DK DK94102557T patent/DK0612741T3/da active
- 1994-02-21 EP EP94102557A patent/EP0612741B1/de not_active Expired - Lifetime
- 1994-02-21 KR KR1019940003193A patent/KR100322319B1/ko not_active Expired - Fee Related
- 1994-02-21 UA UA94005097A patent/UA39099C2/uk unknown
- 1994-02-21 PH PH47791A patent/PH30602A/en unknown
- 1994-02-21 MX MX9401315A patent/MX9401315A/es unknown
- 1994-02-21 SG SG1996002477A patent/SG52300A1/en unknown
- 1994-02-21 NO NO940595A patent/NO305081B1/no not_active IP Right Cessation
- 1994-02-21 HU HU9400493A patent/HU222112B1/hu not_active IP Right Cessation
- 1994-02-21 AT AT94102557T patent/ATE167185T1/de not_active IP Right Cessation
- 1994-02-21 DE DE59406157T patent/DE59406157D1/de not_active Expired - Fee Related
- 1994-02-21 CZ CZ94374A patent/CZ37494A3/cs unknown
- 1994-02-22 CN CN94102252A patent/CN1048490C/zh not_active Expired - Fee Related
- 1994-02-22 NZ NZ250944A patent/NZ250944A/en unknown
- 1994-02-22 IL IL108733A patent/IL108733A/en not_active IP Right Cessation
- 1994-02-22 US US08/200,125 patent/US5519036A/en not_active Expired - Lifetime
1995
- 1995-05-02 US US08/434,136 patent/US5612335A/en not_active Expired - Lifetime
1996
- 1996-12-17 US US08/768,365 patent/US5827849A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2116068A1 (en)	1994-08-23
JP3545446B2 (ja)	2004-07-21
DE4332168A1 (de)	1995-03-23
IL108733A0 (en)	1994-05-30
FI940806A7 (fi)	1994-08-23
PH30602A (en)	1997-07-31
EP0612741B1 (de)	1998-06-10
MX9401315A (es)	1994-08-31
NO305081B1 (no)	1999-03-29
HU222112B1 (hu)	2003-04-28
US5519036A (en)	1996-05-21
DK0612741T3 (da)	1999-03-29
CZ37494A3 (en)	1994-12-15
CN1048490C (zh)	2000-01-19
HU9400493D0 (en)	1994-05-30
EP0612741A1 (de)	1994-08-31
AU673875B2 (en)	1996-11-28
CN1099755A (zh)	1995-03-08
KR100322319B1 (ko)	2002-06-26
HUT70768A (en)	1995-10-30
NO940595D0 (no)	1994-02-21
UA39099C2 (uk)	2001-06-15
FI940806A0 (fi)	1994-02-21
JPH06256343A (ja)	1994-09-13
FI940806L (fi)	1994-08-23
IL108733A (en)	1998-01-04
AU5632494A (en)	1994-08-25
PL178215B1 (pl)	2000-03-31
NZ250944A (en)	1996-02-27
ES2118992T3 (es)	1998-10-01
US5612335A (en)	1997-03-18
ATE167185T1 (de)	1998-06-15
DE59406157D1 (de)	1998-07-16
NO940595L (no)	1994-08-23
KR940019704A (ko)	1994-09-14
US5827849A (en)	1998-10-27

Publication	Publication Date	Title
PH30602A (en)	1997-07-31	Cyclic derivatives pharmaceutical compositions containing these compounds and processes for preparing them
AU1608692A (en)	1992-11-12	Amidinophenylalanine derivatives, a process for the preparation thereof, use thereof and agents containing these as anticoagulants
HU9401445D0 (en)	1994-08-29	Nor-bile-acid derivatives, process for producing them and pharmaceutical compositions containing them
AU673893B2 (en)	1996-11-28	New pyridothiadiazones, processes for their preparation and the pharmaceutical compositions which contain them
AU663200B2 (en)	1995-09-28	New 3-(hydroxybenzylidenyl)-indolin-2-ones, processes for their preparation and pharmaceutical compositions containing them
AU2125192A (en)	1993-02-25	New naphthylethlylureas and naphthylethylthioureas, process for the preparation thereof, and pharmaceutical compositions containing them
AU656466B2 (en)	1995-02-02	New benzimidazole compounds, a process for their preparation and pharmaceutical compositions containing them
FI960658A0 (fi)	1996-02-14	Uudet bis-naftalimidit syövän hoitamiseksi
ES460286A1 (es)	1978-04-01	Un procedimiento de preparacion de espiro(1,3-dioxolan-4,3) quinuclidina.
AU3559793A (en)	1993-10-07	New 3-aminochroman spiro compounds, processes for their preparation and pharmaceutical compositions containing them
HUT60275A (en)	1992-08-28	Process for producing 7-acyl-3-(substituted carbamoyloxy)-cef-3-em-4-carboxylic acid derivatives and pharmaceutical compositions comprising such compounds
IL108997A0 (en)	1994-06-24	Heterotricyclically substituted phenyl-cyclohexane-carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
WO1992009574A3 (en)	1992-08-06	Poly-aminopyrrolecarboxamido derivatives, processes for their preparation and pharmaceutical compositions containing them
CY2160B1 (en)	2002-08-23	Erburnane derivatives processes for their preparation and pharmaceutical compositions containing them
AU6187394A (en)	1994-11-03	New pyrrolopyrazine compounds, processes for their preparation and the pharmaceutical compositions which contain them
ZA941196B (en)	1994-09-20	Angiopeptin cyclopeptide compounds process for the preparation thereof and pharmaceutical compositions containing them
AU6860794A (en)	1995-02-02	(Thia)cycloalkyl(b)indoles, process for preparing them and pharmaceutical compositions containing them
ZA934708B (en)	1994-01-24	Peptide compounds active in cell adhesion processes, a process for the preparation thereof, and pharmaceutical compositions containing them
EP0175284A3 (en)	1986-12-17	Novel antibiotics, process for their preparation and pharmaceutical compositions containing them
HUT68015A (en)	1995-05-29	New compound leustroducsin h, its preparation and pharmaceutical compositions containing them