SG61791G - Amido substituted naphtalene and intermediates thereof - Google Patents

Amido substituted naphtalene and intermediates thereof

Info

Publication number: SG61791G
Authority: SG; Singapore
Prior art keywords: intermediates; amido substituted; naphtalene; substituted naphtalene; amido
Prior art date: 1986-09-26

Application number

SG617/91A

Other languages

English (en)

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-09-26

Filing date

1991-07-26

Publication date

1991-08-23

1991-07-26 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

1991-08-23 Publication of SG61791G publication Critical patent/SG61791G/en

Links

UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical class C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 title 2
125000003368 amide group Chemical group 0.000 title 1
239000000543 intermediate Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SG617/91A 1986-09-26 1991-07-26 Amido substituted naphtalene and intermediates thereof SG61791G (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/912,901 US4681894A (en)	1986-09-26	1986-09-26	Hydroxamic acids and esters

Publications (1)

Publication Number	Publication Date
SG61791G true SG61791G (en)	1991-08-23

Family

ID=25432659

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG617/91A SG61791G (en)	1986-09-26	1991-07-26	Amido substituted naphtalene and intermediates thereof

Country Status (14)

Country	Link
US (1)	US4681894A (de)
EP (1)	EP0261759B1 (de)
JP (1)	JPS6383045A (de)
KR (1)	KR880003898A (de)
AU (1)	AU592434B2 (de)
CA (1)	CA1284336C (de)
DE (1)	DE3769418D1 (de)
DK (1)	DK241987A (de)
ES (1)	ES2038176T3 (de)
GR (1)	GR3001804T3 (de)
HK (1)	HK66191A (de)
PT (1)	PT85786B (de)
SG (1)	SG61791G (de)
ZA (1)	ZA873395B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5189178A (en) *	1990-11-21	1993-02-23	Galardy Richard E	Matrix metalloprotease inhibitors
US5183900A (en) *	1990-11-21	1993-02-02	Galardy Richard E	Matrix metalloprotease inhibitors
US5239078A (en) *	1990-11-21	1993-08-24	Glycomed Incorporated	Matrix metalloprotease inhibitors
US5268384A (en) *	1990-11-21	1993-12-07	Galardy Richard E	Inhibition of angiogenesis by synthetic matrix metalloprotease inhibitors
US5117054A (en) *	1991-09-26	1992-05-26	Ortho Pharmaceutical Corporation	N-hydroxy, N-methyl propanamides
US5594106A (en) *	1993-08-23	1997-01-14	Immunex Corporation	Inhibitors of TNF-α secretion
WO1995032944A1 (en) *	1994-05-28	1995-12-07	British Biotech Pharmaceuticals Limited	Succinyl hydroxamic acid, n-formyl-n-hydroxy amino carboxylic acid and succinic acid amide derivatives as metalloprotease inhibitors
US5891916A (en) *	1995-06-21	1999-04-06	Takeda Chemical Industries, Ltd.	Aromatic hydroxamix acid compounds, their production and use
IT1283637B1 (it) *	1996-05-14	1998-04-23	Italfarmaco Spa	Composti ad attivita' antinfiammatoria ed immunosoppressiva
AU2001248701A1 (en) *	2000-03-24	2001-10-03	Methylgene, Inc.	Inhibitors of histone deacetylase
US20060106102A1 (en) *	2002-06-07	2006-05-18	Eric Morand	Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif)
CA2676946A1 (en)	2009-08-28	2011-02-28	Lucie Peduto	Adam12 inhibitors and their use against inflammation-induced fibrosis
WO2017134265A1 (en)	2016-02-05	2017-08-10	Institut Pasteur	Use of inhibitors of adam12 as adjuvants in tumor therapies

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE141253C (de) *
DE140836C (de) *
US4218478A (en) *	1979-01-05	1980-08-19	Ruiko Oiwa	Trichostatin as an antiprotozoal agent
US4607053A (en) *	1984-05-17	1986-08-19	E. R. Squibb & Sons, Inc.	Arylhydroxamates useful as antiallergy agents
US4604407A (en) *	1985-04-04	1986-08-05	E. R. Squibb & Sons, Inc.	Hydroxamates
US4605669A (en) *	1985-04-26	1986-08-12	Abbott Laboratories	Lipoxygenase inhibiting naphthohydroxamic acids
US4608390A (en) *	1985-04-26	1986-08-26	Abbott Laboratories	Lipoxygenase inhibiting compounds
US4623661A (en) *	1985-04-26	1986-11-18	Abbott Laboratories	Lipoxygenase inhibiting compounds

1986
- 1986-09-26 US US06/912,901 patent/US4681894A/en not_active Expired - Lifetime
1987
- 1987-05-11 DE DE8787304181T patent/DE3769418D1/de not_active Expired - Lifetime
- 1987-05-11 ES ES198787304181T patent/ES2038176T3/es not_active Expired - Lifetime
- 1987-05-11 EP EP87304181A patent/EP0261759B1/de not_active Expired - Lifetime
- 1987-05-12 DK DK241987A patent/DK241987A/da not_active Application Discontinuation
- 1987-05-12 AU AU72747/87A patent/AU592434B2/en not_active Ceased
- 1987-05-12 ZA ZA873395A patent/ZA873395B/xx unknown
- 1987-05-20 CA CA000537498A patent/CA1284336C/en not_active Expired - Lifetime
- 1987-05-23 JP JP62126837A patent/JPS6383045A/ja active Pending
- 1987-05-25 KR KR870005151A patent/KR880003898A/ko not_active Withdrawn
- 1987-09-24 PT PT85786A patent/PT85786B/pt not_active IP Right Cessation
1991
- 1991-04-18 GR GR91400452T patent/GR3001804T3/el unknown
- 1991-07-26 SG SG617/91A patent/SG61791G/en unknown
- 1991-08-22 HK HK661/91A patent/HK66191A/xx unknown

Also Published As

Publication number	Publication date
HK66191A (en)	1991-08-30
AU7274787A (en)	1988-03-31
EP0261759A2 (de)	1988-03-30
EP0261759B1 (de)	1991-04-17
JPS6383045A (ja)	1988-04-13
ES2038176T3 (es)	1993-07-16
KR880003898A (ko)	1988-05-31
DE3769418D1 (de)	1991-05-23
AU592434B2 (en)	1990-01-11
DK241987A (da)	1988-03-27
US4681894A (en)	1987-07-21
ZA873395B (en)	1988-12-28
GR3001804T3 (en)	1992-11-23
PT85786B (pt)	1990-08-31
DK241987D0 (da)	1987-05-12
EP0261759A3 (en)	1988-08-31
CA1284336C (en)	1991-05-21
PT85786A (en)	1987-10-01

Publication	Publication Date	Title
GR3001804T3 (en)	1992-11-23	Amido substituted naphthalene and intermediates thereof
GB2168065B (en)	1990-04-25	Polyanhydride-siloxanes and polyimide-siloxanes obtained therefrom
GB8705940D0 (en)	1987-04-15	Intermediates
IL74630A (en)	1988-04-29	Preparation of 2-oxindole-1-carboxamides and n-chlorosulfonyl-2-oxindole-1-carboxamide intermediates therefor
DE3563624D1 (en)	1988-08-11	Novel substituted trifluorooxetane and preparation thereof
PH20880A (en)	1987-05-27	Substituted benzoxepines and isochromanes
EP0199485A3 (en)	1987-09-02	Intermediates and process
IE860118L (en)	1986-07-18	Pyrrolobenzimidazoles and intermediates thereof
ZA858247B (en)	1986-06-25	Benzoylureas and intermediates
NZ222612A (en)	1991-07-26	Benzoquinolines and pharmaceutical compositions: intermediates
GB8400986D0 (en)	1984-02-15	Releasable fastening
IE862508L (en)	1987-03-24	Heterobicycloalkanes and intermediates
IE850337L (en)	1985-08-13	Benzothiazolopyrimidinones and intermediates thereof
IE851068L (en)	1985-10-27	Dibenzoxepins and intermediates thereof
IE843013L (en)	1986-05-23	Dihydropyridines and intermediates therefor
GB2191482B (en)	1990-01-17	Substituted pyrimidoindoles and diazepinoindoles
IL92781A0 (en)	1990-09-17	Preparation of 5-acylamino-1,2,4-triazole-3-sulfonamides and intermediates
IE871086L (en)	1987-10-28	Thieno-pyrimidines and intermediates
IE862142L (en)	1987-02-10	Pyrazoline derivatives and intermediates thereof
IE840760L (en)	1984-09-29	Thienopyridoindoles and intermediates therefor
IE891219L (en)	1989-10-18	Bicyclodiones and intermediates
IL96155A (en)	1992-01-15	3beta-(4(s)-aryloxazolidin-2-one-3-yl)azetidin-2-one intermediates and their preparation
IE851223L (en)	1985-11-17	Isoxazolidines and related intermediates
IE890605L (en)	1989-08-25	Dihydropyridines and intermediates
KR870003043U (ko)	1987-03-19	튜너의 tp단자