SK124698A3 - Recombinant adenoviral vectors for human tumour gene therapy - Google Patents

Recombinant adenoviral vectors for human tumour gene therapy Download PDF

Info

Publication number: SK124698A3
Authority: SK; Slovakia
Prior art keywords: mage; cells; nucleic acid; defective recombinant; recombinant adenovirus
Prior art date: 1996-03-14

Application number

SK1246-98A

Other languages

English (en)

Slovak (sk)

Inventor

Falleur Boon

Marie-Therese Duffour

Hedi Haddada

Christophe Lurquin

Michel Perricaudet

Catherine Uyttenhoveghesquiere

Guy Warnier

Original Assignee

Rhone Poulenc Rorer Sa

Ludwig Inst Cancer Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-14

Filing date

1997-03-12

Publication date

1999-05-07

1997-03-12 Application filed by Rhone Poulenc Rorer Sa, Ludwig Inst Cancer Res filed Critical Rhone Poulenc Rorer Sa

1999-05-07 Publication of SK124698A3 publication Critical patent/SK124698A3/sk

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Biophysics (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
General Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Microbiology (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Cell Biology (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Epidemiology (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SK1246-98A 1996-03-14 1997-03-12 Recombinant adenoviral vectors for human tumour gene therapy SK124698A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9603207A FR2746110B1 (fr)	1996-03-14	1996-03-14	Methode de traitement par therapie genique des tumeurs humaines et virus recombinants correspondants
PCT/FR1997/000435 WO1997034009A1 (fr)	1996-03-14	1997-03-12	Vecteurs adenoviraux recombinants pour la therapie genique des tumeurs humaines

Publications (1)

Publication Number	Publication Date
SK124698A3 true SK124698A3 (en)	1999-05-07

Family

ID=9490181

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1246-98A SK124698A3 (en)	1996-03-14	1997-03-12	Recombinant adenoviral vectors for human tumour gene therapy

Country Status (19)

Country	Link
US (1)	US20030082150A1 (de)
EP (1)	EP0889969B1 (de)
JP (1)	JP2000507229A (de)
KR (1)	KR19990087718A (de)
CN (1)	CN1218512A (de)
AT (1)	ATE309382T1 (de)
AU (1)	AU732288B2 (de)
BR (1)	BR9707994A (de)
CA (1)	CA2248612A1 (de)
CZ (1)	CZ295967B6 (de)
DE (1)	DE69734574T2 (de)
DK (1)	DK0889969T3 (de)
ES (1)	ES2252779T3 (de)
FR (1)	FR2746110B1 (de)
HU (1)	HUP9902150A3 (de)
IL (1)	IL126152A0 (de)
NO (1)	NO984052L (de)
SK (1)	SK124698A3 (de)
WO (1)	WO1997034009A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998015638A2 (en) *	1996-10-07	1998-04-16	Ludwig Institute For Cancer Research	Replication-defective adenoviruses for cancer immunotherapy
ATE395930T1 (de)	1999-10-22	2008-06-15	Aventis Pasteur	Verfahren zur erregung und/oder verstärkung der immunantwort gegen tumorantigene
DK1282702T3 (da) *	2000-05-10	2007-04-02	Sanofi Pasteur Ltd	Immunogene polypeptider, som er kodet af KAGE-minigener, og anvendelser deraf
CN1520303B (zh) *	2001-03-27	2013-04-24	纽约大学	利用基于α病毒且靶向高亲和性层粘连蛋白受体的载体进行肿瘤治疗
AU2004280608B2 (en) *	2002-04-09	2012-04-05	Sanofi Pasteur, Inc.	Modified CEA/B7 vector
EP1864691B1 (de)	2002-04-09	2011-07-20	Sanofi Pasteur Limited	Modifizierte CEA-Nukleinsäure und entsprechende Expressionsvektoren
JP2005523942A (ja) *	2002-04-30	2005-08-11	アヴィオルセラピューティクスインコーポレイテッド	免疫療法のためのアデノウイルスベクター
CN1327000C (zh) *	2002-09-06	2007-07-18	中国人民解放军军事医学科学院基础医学研究所	靶向黑色素瘤的可复制性腺病毒穿梭载体及腺病毒
WO2004037284A1 (en) *	2002-10-22	2004-05-06	Sanofi Pasteur Limited	Anti-cancer vaccines and high-dose cytokines as adjuvants
AU2014236207B2 (en)	2013-03-14	2019-05-23	Salk Institute For Biological Studies	Oncolytic adenovirus compositions
KR20250081944A (ko)	2014-09-24	2025-06-05	솔크 인스티튜트 포 바이올로지칼 스터디즈	종양 살상 바이러스 및 이의 사용방법
WO2017147265A1 (en)	2016-02-23	2017-08-31	Salk Institute For Biological Studies	High throughput assay for measuring adenovirus replication kinetics
EP4155411A1 (de)	2016-02-23	2023-03-29	Salk Institute for Biological Studies	Exogene genexpression eines therapeutischen adenovirus mit geringem einfluss auf die virale kinetik
EP3532082A4 (de)	2016-12-12	2020-08-26	Salk Institute for Biological Studies	Auf tumoren gerichtete synthetische adenoviren und verwendungen davon
MX2020010499A (es)	2018-04-09	2020-10-28	Salk Inst For Biological Studi	Composiciones de adenovirus oncoliticas con propiedades aumentadas de replicacion.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6235525B1 (en) *	1991-05-23	2001-05-22	Ludwig Institute For Cancer Research	Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-3 and uses thereof
US5342774A (en) *	1991-05-23	1994-08-30	Ludwig Institute For Cancer Research	Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1
US5620886A (en) *	1993-03-18	1997-04-15	Ludwig Institute For Cancer Research	Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2
BR9405507A (pt) *	1993-07-13	1999-05-25	Rhone Poulenc Rorer Sa	Adenovirus recombinante defeituoso linhagem celular e composição farmaceutica

1996
- 1996-03-14 FR FR9603207A patent/FR2746110B1/fr not_active Expired - Fee Related
1997
- 1997-03-12 AU AU21641/97A patent/AU732288B2/en not_active Ceased
- 1997-03-12 JP JP9532334A patent/JP2000507229A/ja not_active Ceased
- 1997-03-12 BR BR9707994A patent/BR9707994A/pt not_active Application Discontinuation
- 1997-03-12 EP EP97914375A patent/EP0889969B1/de not_active Expired - Lifetime
- 1997-03-12 ES ES97914375T patent/ES2252779T3/es not_active Expired - Lifetime
- 1997-03-12 KR KR1019980707186A patent/KR19990087718A/ko not_active Ceased
- 1997-03-12 SK SK1246-98A patent/SK124698A3/sk unknown
- 1997-03-12 WO PCT/FR1997/000435 patent/WO1997034009A1/fr not_active Ceased
- 1997-03-12 AT AT97914375T patent/ATE309382T1/de not_active IP Right Cessation
- 1997-03-12 CA CA002248612A patent/CA2248612A1/fr not_active Abandoned
- 1997-03-12 IL IL12615297A patent/IL126152A0/xx unknown
- 1997-03-12 DK DK97914375T patent/DK0889969T3/da active
- 1997-03-12 DE DE69734574T patent/DE69734574T2/de not_active Expired - Fee Related
- 1997-03-12 CZ CZ19982915A patent/CZ295967B6/cs unknown
- 1997-03-12 CN CN97193960A patent/CN1218512A/zh active Pending
- 1997-03-12 US US09/125,887 patent/US20030082150A1/en not_active Abandoned
- 1997-03-12 HU HU9902150A patent/HUP9902150A3/hu unknown
1998
- 1998-09-03 NO NO984052A patent/NO984052L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
FR2746110B1 (fr)	1998-04-17
CA2248612A1 (fr)	1997-09-18
US20030082150A1 (en)	2003-05-01
CN1218512A (zh)	1999-06-02
AU2164197A (en)	1997-10-01
EP0889969B1 (de)	2005-11-09
DE69734574T2 (de)	2006-07-13
KR19990087718A (ko)	1999-12-27
NO984052D0 (no)	1998-09-03
CZ295967B6 (cs)	2005-12-14
DK0889969T3 (da)	2006-03-27
BR9707994A (pt)	1999-07-27
EP0889969A1 (de)	1999-01-13
ES2252779T3 (es)	2006-05-16
AU732288B2 (en)	2001-04-12
CZ291598A3 (cs)	1998-12-16
IL126152A0 (en)	1999-05-09
FR2746110A1 (fr)	1997-09-19
HUP9902150A3 (en)	2000-12-28
DE69734574D1 (de)	2005-12-15
NO984052L (no)	1998-09-03
JP2000507229A (ja)	2000-06-13
HUP9902150A2 (hu)	1999-11-29
ATE309382T1 (de)	2005-11-15
WO1997034009A1 (fr)	1997-09-18

Publication	Publication Date	Title
SK124698A3 (en)	1999-05-07	Recombinant adenoviral vectors for human tumour gene therapy
CN1143386A (zh)	1997-02-19	转化生长因子α-H1
WO1998046769A1 (en)	1998-10-22	Composition and method for inducing an immune response against tumour-related antigens
KR20000071226A (ko)	2000-11-25	간세포 암의 예방 및 치료 방법
US20070104685A1 (en)	2007-05-10	Synthetic gene encoding human carcinoembryonic antigen and uses thereof
US7282365B2 (en)	2007-10-16	Rhesus HER2/neu, nucleotides encoding same, and uses thereof
CN1157828A (zh)	1997-08-27	抑制性卡巴B蛋白(IkB)的截短形式，及其重组产物和应用
KR20080098585A (ko)	2008-11-11	엡스타인-바르 바이러스 관련 질환의 치료
US20020177547A1 (en)	2002-11-28	Pharmaceutical compositions for treating or preventing cancer
MXPA98007290A (en)	1999-10-14	Recombinant adenoviral vectors for the genuine therapy of the huma tumors
US20060286114A1 (en)	2006-12-21	Synthetic gene encoding rhesus monkey carcinoembryonic antigen and uses thereof
EP1597370B1 (de)	2006-06-28	Rhesus-karzinoembryonales antigen, dieses codierende nukleotide und verwendungen davon
ES2247594T3 (es)	2006-03-01	Proteina antivirica.
JPWO2004058299A1 (ja)	2006-04-27	ポリヌクレオチドからなるワクチン
WO2024192085A1 (en)	2024-09-19	Recombinant oncolytic adenovirus for cancer therapy
CN116948005A (zh)	2023-10-27	一种病毒递送的新型细胞因子及在肿瘤治疗中的应用
ZA200508013B (en)	2007-10-31	Synthetic gene encoding human carcinoembryonic antigen and use thereof
WO2004015098A2 (en)	2004-02-19	Rhesus epithelial cell adhesion molecule, nucleic acid encoding the same, and uses thereof
HK1047116A1 (zh)	2003-02-07	來自mage的免疫原性肽及其應用
JP2002369685A (ja)	2002-12-24	アポトーシス遺伝子１のヒトインヒビター