SK124699A3 - Activated vitamin k-dependent blood factor and method for the production thereof - Google Patents

Activated vitamin k-dependent blood factor and method for the production thereof Download PDF

Info

Publication number: SK124699A3
Authority: SK; Slovakia
Prior art keywords: factor; protease; activation; activating; protein
Prior art date: 1997-03-12

Application number

SK1246-99A

Other languages

English (en)

Slovak (sk)

Inventor

Peter Turecek

Gunter Richter

Anton Philapitsch

Hans-Peter Schwarz

Johann Eibl

Original Assignee

Baxter Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-03-12

Filing date

1998-03-10

Publication date

2000-06-12

1998-03-10 Application filed by Baxter Ag filed Critical Baxter Ag

2000-06-12 Publication of SK124699A3 publication Critical patent/SK124699A3/sk

Links

238000000034 method Methods 0.000 title claims abstract description 40
229960000182 blood factors Drugs 0.000 title claims abstract description 27
230000001419 dependent effect Effects 0.000 title claims abstract description 11
229940046010 vitamin k Drugs 0.000 title claims abstract description 11
238000004519 manufacturing process Methods 0.000 title description 4
239000004365 Protease Substances 0.000 claims abstract description 90
108091005804 Peptidases Proteins 0.000 claims abstract description 67
230000003213 activating effect Effects 0.000 claims abstract description 29
229930003448 Vitamin K Natural products 0.000 claims abstract description 10
SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 claims abstract description 10
235000019168 vitamin K Nutrition 0.000 claims abstract description 10
239000011712 vitamin K Substances 0.000 claims abstract description 10
150000003721 vitamin K derivatives Chemical class 0.000 claims abstract description 10
239000000825 pharmaceutical preparation Substances 0.000 claims abstract description 8
102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims abstract 14
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KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
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239000000419 plant extract Substances 0.000 description 1
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235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Hematology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Medicines Containing Plant Substances (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

SK1246-99A 1997-03-12 1998-03-10 Activated vitamin k-dependent blood factor and method for the production thereof SK124699A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19710190A DE19710190A1 (de)	1997-03-12	1997-03-12	Aktivierter Vitamin K-abhängiger Blutfaktor und Verfahren zu dessen Herstellung
PCT/EP1998/001364 WO1998040474A2 (fr)	1997-03-12	1998-03-10	Facteur sanguin active dependant de la vitamine k et procede de preparation dudit facteur

Publications (1)

Publication Number	Publication Date
SK124699A3 true SK124699A3 (en)	2000-06-12

Family

ID=7823110

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1246-99A SK124699A3 (en)	1997-03-12	1998-03-10	Activated vitamin k-dependent blood factor and method for the production thereof

Country Status (9)

Country	Link
EP (1)	EP0968280A1 (fr)
JP (1)	JP2001514516A (fr)
AU (1)	AU740727B2 (fr)
CA (1)	CA2284122A1 (fr)
DE (1)	DE19710190A1 (fr)
HU (1)	HUP0001505A3 (fr)
NO (1)	NO994394L (fr)
SK (1)	SK124699A3 (fr)
WO (1)	WO1998040474A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR102331A1 (es) *	2014-08-12	2017-02-22	Baxalta Inc	Activación del factor x

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE13810T1 (de) *	1981-06-25	1985-07-15	Serapharm Gmbh & Co Kg	Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundabdeckung.
WO1991002065A1 (fr) *	1989-08-11	1991-02-21	Zymogenetics, Inc.	Procedes de culture de cellules pour la production de proteine c activee
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WO1993009807A1 (fr) *	1991-11-18	1993-05-27	The Scripps Research Institute	Procedes d'inhibition de la thrombose par elevation des taux de proteine c activee endogene dans la circulation
JP3404038B2 (ja) *	1991-12-31	2003-05-06	ザイモジェネティクス，インコーポレイティド	トロンビンの製造方法
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US5514373A (en) *	1992-05-22	1996-05-07	Harris, Jr.; Roosevelt D.	Topical preparation
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1997
- 1997-03-12 DE DE19710190A patent/DE19710190A1/de not_active Withdrawn
1998
- 1998-03-10 HU HU0001505A patent/HUP0001505A3/hu unknown
- 1998-03-10 JP JP53920998A patent/JP2001514516A/ja active Pending
- 1998-03-10 CA CA002284122A patent/CA2284122A1/fr not_active Abandoned
- 1998-03-10 SK SK1246-99A patent/SK124699A3/sk unknown
- 1998-03-10 WO PCT/EP1998/001364 patent/WO1998040474A2/fr not_active Ceased
- 1998-03-10 AU AU68295/98A patent/AU740727B2/en not_active Ceased
- 1998-03-10 EP EP98913692A patent/EP0968280A1/fr not_active Withdrawn
1999
- 1999-09-10 NO NO994394A patent/NO994394L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0968280A1 (fr)	2000-01-05
HUP0001505A1 (hu)	2000-09-28
JP2001514516A (ja)	2001-09-11
HUP0001505A3 (en)	2002-01-28
WO1998040474A3 (fr)	1999-02-11
AU6829598A (en)	1998-09-29
WO1998040474A2 (fr)	1998-09-17
DE19710190A1 (de)	1998-09-17
CA2284122A1 (fr)	1998-09-17
AU740727B2 (en)	2001-11-15
NO994394D0 (no)	1999-09-10
NO994394L (no)	1999-11-11

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AT405516B (de)	1999-09-27	Faktor x-analoge mit modifizierter proteasespaltstelle
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EP0638314A1 (fr)	1995-02-15	Procede pour produire une composition contenant du plasminogene