SK143594A3 - 1,3,4-oxadiazole-2(3h)-on derivatives, method of their preparation and their terapeutical using - Google Patents

1,3,4-oxadiazole-2(3h)-on derivatives, method of their preparation and their terapeutical using Download PDF

Info

Publication number
SK143594A3
SK143594A3 SK1435-94A SK143594A SK143594A3 SK 143594 A3 SK143594 A3 SK 143594A3 SK 143594 A SK143594 A SK 143594A SK 143594 A3 SK143594 A3 SK 143594A3
Authority
SK
Slovakia
Prior art keywords
group
formula
compound
carbon atoms
phenyl
Prior art date
Application number
SK1435-94A
Other languages
English (en)
Slovak (sk)
Inventor
Jean-Jacques Koenig
Samir Jegham
Frederic Puech
Philippe Burnier
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of SK143594A3 publication Critical patent/SK143594A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1435-94A 1993-11-26 1994-11-25 1,3,4-oxadiazole-2(3h)-on derivatives, method of their preparation and their terapeutical using SK143594A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9314151A FR2712886B1 (fr) 1993-11-26 1993-11-26 Dérivés de 1,3,4-oxadiazol-2(3H)-one, leur préparation et leur application en thérapeutique.

Publications (1)

Publication Number Publication Date
SK143594A3 true SK143594A3 (en) 1995-06-07

Family

ID=9453245

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1435-94A SK143594A3 (en) 1993-11-26 1994-11-25 1,3,4-oxadiazole-2(3h)-on derivatives, method of their preparation and their terapeutical using

Country Status (24)

Country Link
US (1) US5525619A (de)
EP (1) EP0655445B1 (de)
JP (1) JPH07196636A (de)
KR (1) KR950014088A (de)
CN (1) CN1106395A (de)
AT (1) ATE157356T1 (de)
AU (1) AU679127B2 (de)
CA (1) CA2136669A1 (de)
CZ (1) CZ291794A3 (de)
DE (1) DE69405198T2 (de)
DK (1) DK0655445T3 (de)
ES (1) ES2107157T3 (de)
FI (1) FI945562A7 (de)
FR (1) FR2712886B1 (de)
GR (1) GR3025272T3 (de)
HU (1) HUT71111A (de)
IL (1) IL111769A (de)
NO (1) NO944513L (de)
NZ (1) NZ264991A (de)
PL (1) PL305999A1 (de)
RU (1) RU94042230A (de)
SK (1) SK143594A3 (de)
TW (1) TW284761B (de)
ZA (1) ZA949394B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763068B1 (fr) * 1997-05-06 1999-06-04 Synthelabo Derives de 3-(pyrrolidin-3-yl)-1,3,4-oxadiazol-2(3h)-one, leur preparation et leur application en therapeutique
FR2766485B1 (fr) * 1997-07-23 2002-05-24 Synthelabo Derives de 2,4-dihydro-3h-1,2,4-triazol-3-one, leur prparation et leur application en therapeutique
JP2001039954A (ja) * 1999-05-24 2001-02-13 Tomono Agrica Co Ltd ヘテロ環誘導体
US6326388B1 (en) * 1999-12-21 2001-12-04 Celgene Corporation Substituted 1,3,4-oxadiazoles and a method of reducing TNF-alpha level
CN104016938B (zh) * 2014-05-28 2016-08-17 浙江工业大学 一种含苯硒基的噁二唑类化合物及其制备与应用
CN104016939B (zh) * 2014-05-28 2016-06-15 浙江工业大学 一种2-亚乙基-3-乙酰基-1,3,4-噁二唑类化合物及其制备与应用
GB201814151D0 (en) * 2018-08-31 2018-10-17 Ucl Business Plc Compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2631827B1 (fr) * 1988-05-27 1992-03-27 Delalande Sa Nouveaux derives d'(hetero)aryl-5 tetrazole, leur procede de preparation et leur application en therapeutique
JPH0366056A (ja) * 1989-08-03 1991-03-20 Matsushita Electric Ind Co Ltd 回転ヘッド装置
FR2655044B1 (fr) * 1989-11-24 1995-03-03 Delalande Sa Derives d'(hetero) arylmethyloxy-4 phenyl tetrazole et oxadiazole, leur procede de preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
NO944513L (no) 1995-05-29
ZA949394B (en) 1995-09-07
NZ264991A (en) 1995-07-26
TW284761B (de) 1996-09-01
RU94042230A (ru) 1996-11-20
ES2107157T3 (es) 1997-11-16
ATE157356T1 (de) 1997-09-15
FI945562L (fi) 1995-05-27
CA2136669A1 (en) 1995-05-27
US5525619A (en) 1996-06-11
EP0655445B1 (de) 1997-08-27
CN1106395A (zh) 1995-08-09
FI945562A7 (fi) 1995-05-27
DE69405198T2 (de) 1998-01-29
HU9403393D0 (en) 1995-02-28
KR950014088A (ko) 1995-06-15
IL111769A (en) 1999-04-11
AU679127B2 (en) 1997-06-19
PL305999A1 (en) 1995-05-29
GR3025272T3 (en) 1998-02-27
EP0655445A1 (de) 1995-05-31
AU7903094A (en) 1995-06-01
IL111769A0 (en) 1995-01-24
FR2712886A1 (fr) 1995-06-02
NO944513D0 (no) 1994-11-25
FR2712886B1 (fr) 1996-01-05
CZ291794A3 (en) 1995-07-12
DE69405198D1 (de) 1997-10-02
JPH07196636A (ja) 1995-08-01
FI945562A0 (fi) 1994-11-25
DK0655445T3 (da) 1998-03-23
HUT71111A (en) 1995-11-28

Similar Documents

Publication Publication Date Title
EP1674452A1 (de) Neues 4-phenylaminobenzaldoximderivatie und dessen verwendung als mek-inhibitor
WO1992012148A1 (en) 1,4-benzothiazepine derivative
US20100234599A1 (en) Method for preparing acid addition salts of polyacidic basic compounds
KR20060133592A (ko) 알킬피페라진- 및 알킬호모피페라진-카르복실레이트의유도체, 이의 제조 방법 및 faah 효소 억제제로서의용도
JP2840288B2 (ja) 置換1―(1h―イミダゾール―4―イル)アルキル―ベンズアミド
BG61729B1 (bg) 9-заместени-2-(2-норм-алкоксифенил)пурин-6-они
EP2623503B1 (de) Für die behandlung einer durch tcr-nck-interaktion vermittelten krankheit geeignete chromenderivate
US5356916A (en) 1,2,4-oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity
CZ291794A3 (en) Derivatives of 1,3,4-oxadiazol-2(3h)-one, process of their preparation and their therapeutical use
JP3169188B2 (ja) カルバミン酸誘導体及びその製造方法
JP3093419B2 (ja) 1,4‐ベンゾチアゼピン誘導体
JP2008523031A (ja) 部分的ドーパミン−d2受容体作動性とセロトニン再摂取阻害の組み合わせを示すフェニルピペラジン誘導体
US4849423A (en) Purine derivatives, medicaments containing them and methods of treating cardiac insufficiencies and irregularities with them.
JP2024535860A (ja) Gpr52モジュレーター化合物
JP5080458B2 (ja) 5−ヒドロキシトリプタミンおよびノルエピネフリンの再取込みの阻害のための、またはうつ病障害の治療のための化合物、その製造方法ならびにその使用
WO1997043282A2 (en) Benzothiazolinones as anti-asthmatic agents
US5198450A (en) Phenylalkanoylamine derivatives, process for preparing the same, and usage of the same
HU194193B (en) Process for preparing new 4-/amino-methylidene/-3-aryl-5/4h/-isoxazolinone derivatives and pharmaceutical compositions containing such compounds as active ingredients
WO2025238416A1 (en) Indole derivatives, uses and compositions thereof
EP0034752A1 (de) Phenoxyalkanderivat und Verfahren zu dessen Herstellung
WO2024175985A1 (en) Development of trimethyllysine hydroxylase (tmlh) inhibitors
EP1709016A1 (de) Cyclische diaminverbindung und diese enthaltendes pharmazeutikum
HK1186727B (en) Chromene derivatives useful in the treatment of a disease mediated by the tcr-nck interaction
JPWO1995029163A1 (ja) イミダゾール誘導体及びその製造方法