SK19602000A3 - Liečivá obsahujúce bisfosfónové kyseliny a ich deriváty na profylaxiu a ošetrovanie autoimúnnych ochorení a alergií - Google Patents
Liečivá obsahujúce bisfosfónové kyseliny a ich deriváty na profylaxiu a ošetrovanie autoimúnnych ochorení a alergií Download PDFInfo
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- SK19602000A3 SK19602000A3 SK1960-2000A SK19602000A SK19602000A3 SK 19602000 A3 SK19602000 A3 SK 19602000A3 SK 19602000 A SK19602000 A SK 19602000A SK 19602000 A3 SK19602000 A3 SK 19602000A3
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- 235000019437 butane-1,3-diol Nutrition 0.000 description 1
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- 235000013539 calcium stearate Nutrition 0.000 description 1
- 239000008116 calcium stearate Substances 0.000 description 1
- OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 210000003850 cellular structure Anatomy 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 235000010980 cellulose Nutrition 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 229940110456 cocoa butter Drugs 0.000 description 1
- 235000019868 cocoa butter Nutrition 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- 230000001085 cytostatic effect Effects 0.000 description 1
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- 239000003085 diluting agent Substances 0.000 description 1
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- 229940047652 ear drops Drugs 0.000 description 1
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- 208000006881 esophagitis Diseases 0.000 description 1
- 229940093499 ethyl acetate Drugs 0.000 description 1
- 239000010642 eucalyptus oil Substances 0.000 description 1
- 229940044949 eucalyptus oil Drugs 0.000 description 1
- 239000003885 eye ointment Substances 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000020932 food allergy Nutrition 0.000 description 1
- 235000019264 food flavour enhancer Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- SZMNOLSLNRNAJC-UHFFFAOYSA-N formaldehyde;propane-1,2,3-triol Chemical compound O=C.OCC(O)CO SZMNOLSLNRNAJC-UHFFFAOYSA-N 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 description 1
- SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 230000009610 hypersensitivity Effects 0.000 description 1
- 125000002962 imidazol-1-yl group Chemical group [*]N1C([H])=NC([H])=C1[H] 0.000 description 1
- 230000002519 immonomodulatory effect Effects 0.000 description 1
- 210000002865 immune cell Anatomy 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 230000000899 immune system response Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 231100001023 lymphopenia Toxicity 0.000 description 1
- 230000036210 malignancy Effects 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000001525 mentha piperita l. herb oil Substances 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 230000003158 microbiostatic effect Effects 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- CQDGTJPVBWZJAZ-UHFFFAOYSA-N monoethyl carbonate Chemical compound CCOC(O)=O CQDGTJPVBWZJAZ-UHFFFAOYSA-N 0.000 description 1
- 230000031990 negative regulation of inflammatory response Effects 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 210000004789 organ system Anatomy 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 201000001976 pemphigus vulgaris Diseases 0.000 description 1
- 235000019477 peppermint oil Nutrition 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 229960004063 propylene glycol Drugs 0.000 description 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 206010043554 thrombocytopenia Diseases 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19828450A DE19828450A1 (de) | 1998-06-26 | 1998-06-26 | Bisphosphonsäuren und deren Derivate enthaltende Arzneimittel zur Prophylaxe und zur Behandlung von Autoimmunkrankheiten sowie von Allergien |
| PCT/DE1999/001844 WO2000000182A2 (de) | 1998-06-26 | 1999-06-24 | Bisphosphonsäuren und deren derivate enthaltende arzneimittel zur prophylaxe und zur behandlung von autoimmunkrankheiten sowie von allergien |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK19602000A3 true SK19602000A3 (sk) | 2001-07-10 |
Family
ID=7872064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1960-2000A SK19602000A3 (sk) | 1998-06-26 | 1999-06-24 | Liečivá obsahujúce bisfosfónové kyseliny a ich deriváty na profylaxiu a ošetrovanie autoimúnnych ochorení a alergií |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1089761B1 (es) |
| JP (1) | JP2002519319A (es) |
| KR (1) | KR20010053211A (es) |
| AT (1) | ATE224734T1 (es) |
| AU (1) | AU740605B2 (es) |
| CA (1) | CA2334711C (es) |
| DE (2) | DE19828450A1 (es) |
| DK (1) | DK1089761T3 (es) |
| EA (1) | EA200100080A1 (es) |
| EE (1) | EE200000756A (es) |
| ES (1) | ES2184496T3 (es) |
| HR (1) | HRP20000820A2 (es) |
| HU (1) | HUP0102873A3 (es) |
| ID (1) | ID27515A (es) |
| IL (1) | IL139966A0 (es) |
| IS (1) | IS5748A (es) |
| MX (1) | MXPA00012338A (es) |
| NO (1) | NO20006572L (es) |
| NZ (1) | NZ509505A (es) |
| PL (1) | PL345287A1 (es) |
| PT (1) | PT1089761E (es) |
| SK (1) | SK19602000A3 (es) |
| TR (1) | TR200003821T2 (es) |
| WO (1) | WO2000000182A2 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1331597A (zh) | 1998-12-23 | 2002-01-16 | 朱马制药有限公司 | 双膦酸酯用于预防和治疗传染性病变的用途 |
| EP1057488A4 (en) * | 1998-12-25 | 2003-10-22 | Toray Industries | INTERLEUKIN-6 PRODUCTION INHIBITORS |
| PT1392325E (pt) * | 2001-05-02 | 2006-10-31 | Novartis Ag | Metodo de administracao de bifosfonatos por inalacao no tratamento ou na prevencao da reabsorcao ossea e da osteoporose |
| WO2003009855A2 (de) | 2001-07-20 | 2003-02-06 | Bioagency Ag | Organo-phosphorverbindungen zur aktivierung von gamma/delta-t-zellen |
| GB0307989D0 (en) * | 2003-04-07 | 2003-05-14 | Mcewen Lab Ltd | Therapeutic composition |
| EP1930011B1 (en) * | 2004-08-23 | 2011-08-17 | Teva Pharmaceutical Industries Ltd | Crystalline form of ibandronate sodium |
| CN101262856A (zh) * | 2005-09-12 | 2008-09-10 | 雷迪博士实验室有限公司 | 唑来膦酸的结晶三水合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2114946T3 (es) * | 1991-09-05 | 1998-06-16 | Toray Industries | Derivado de acido metanodifosfonico, su produccion y uso medicinal. |
| JP4231106B2 (ja) * | 1995-01-23 | 2009-02-25 | ゼノテック インコーポレイティッド | 骨溶解および転移を改善する方法 |
-
1998
- 1998-06-26 DE DE19828450A patent/DE19828450A1/de not_active Withdrawn
-
1999
- 1999-06-24 EE EEP200000756A patent/EE200000756A/xx unknown
- 1999-06-24 IL IL13996699A patent/IL139966A0/xx unknown
- 1999-06-24 PT PT99941383T patent/PT1089761E/pt unknown
- 1999-06-24 KR KR1020007014813A patent/KR20010053211A/ko not_active Ceased
- 1999-06-24 JP JP2000556767A patent/JP2002519319A/ja active Pending
- 1999-06-24 SK SK1960-2000A patent/SK19602000A3/sk unknown
- 1999-06-24 EA EA200100080A patent/EA200100080A1/ru unknown
- 1999-06-24 ID IDW20002676A patent/ID27515A/id unknown
- 1999-06-24 PL PL99345287A patent/PL345287A1/xx unknown
- 1999-06-24 HR HR20000820A patent/HRP20000820A2/hr not_active Application Discontinuation
- 1999-06-24 TR TR2000/03821T patent/TR200003821T2/xx unknown
- 1999-06-24 ES ES99941383T patent/ES2184496T3/es not_active Expired - Lifetime
- 1999-06-24 NZ NZ509505A patent/NZ509505A/xx not_active IP Right Cessation
- 1999-06-24 DK DK99941383T patent/DK1089761T3/da active
- 1999-06-24 HU HU0102873A patent/HUP0102873A3/hu unknown
- 1999-06-24 DE DE59902856T patent/DE59902856D1/de not_active Expired - Lifetime
- 1999-06-24 MX MXPA00012338A patent/MXPA00012338A/es unknown
- 1999-06-24 EP EP99941383A patent/EP1089761B1/de not_active Expired - Lifetime
- 1999-06-24 AU AU55033/99A patent/AU740605B2/en not_active Ceased
- 1999-06-24 WO PCT/DE1999/001844 patent/WO2000000182A2/de not_active Ceased
- 1999-06-24 CA CA002334711A patent/CA2334711C/en not_active Expired - Fee Related
- 1999-06-24 AT AT99941383T patent/ATE224734T1/de active
-
2000
- 2000-12-01 IS IS5748A patent/IS5748A/is unknown
- 2000-12-21 NO NO20006572A patent/NO20006572L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20006572D0 (no) | 2000-12-21 |
| PT1089761E (pt) | 2003-02-28 |
| NZ509505A (en) | 2002-11-26 |
| EA200100080A1 (ru) | 2001-06-25 |
| EP1089761B1 (de) | 2002-09-25 |
| HRP20000820A2 (en) | 2001-12-31 |
| HUP0102873A3 (en) | 2002-04-29 |
| JP2002519319A (ja) | 2002-07-02 |
| DE19828450A1 (de) | 1999-12-30 |
| NO20006572L (no) | 2001-02-21 |
| DE59902856D1 (de) | 2002-10-31 |
| AU740605B2 (en) | 2001-11-08 |
| WO2000000182A2 (de) | 2000-01-06 |
| IL139966A0 (en) | 2002-02-10 |
| CA2334711C (en) | 2006-12-05 |
| DK1089761T3 (da) | 2003-02-03 |
| TR200003821T2 (tr) | 2001-06-21 |
| PL345287A1 (en) | 2001-12-03 |
| WO2000000182A3 (de) | 2000-03-30 |
| ID27515A (id) | 2001-04-12 |
| KR20010053211A (ko) | 2001-06-25 |
| EE200000756A (et) | 2002-04-15 |
| ATE224734T1 (de) | 2002-10-15 |
| CA2334711A1 (en) | 2000-01-06 |
| HUP0102873A2 (hu) | 2001-12-28 |
| MXPA00012338A (es) | 2003-04-25 |
| EP1089761A2 (de) | 2001-04-11 |
| ES2184496T3 (es) | 2003-04-01 |
| IS5748A (is) | 2000-12-01 |
| AU5503399A (en) | 2000-01-17 |
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