SK20242000A3 - Paroxetínová soľ, spôsob jej prípravy a jej použitie - Google Patents

Paroxetínová soľ, spôsob jej prípravy a jej použitie Download PDF

Info

Publication number
SK20242000A3
SK20242000A3 SK2024-2000A SK20242000A SK20242000A3 SK 20242000 A3 SK20242000 A3 SK 20242000A3 SK 20242000 A SK20242000 A SK 20242000A SK 20242000 A3 SK20242000 A3 SK 20242000A3
Authority
SK
Slovakia
Prior art keywords
acid
benzoic
carboxylic
methyl
chloro
Prior art date
Application number
SK2024-2000A
Other languages
English (en)
Slovak (sk)
Inventor
Victor Witold Jacewicz
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of SK20242000A3 publication Critical patent/SK20242000A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
SK2024-2000A 1998-07-02 1999-06-30 Paroxetínová soľ, spôsob jej prípravy a jej použitie SK20242000A3 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9814316.7A GB9814316D0 (en) 1998-07-02 1998-07-02 Novel compounds
PCT/EP1999/004543 WO2000001692A1 (en) 1998-07-02 1999-06-30 Salts of paroxetine

Publications (1)

Publication Number Publication Date
SK20242000A3 true SK20242000A3 (sk) 2001-07-10

Family

ID=10834803

Family Applications (1)

Application Number Title Priority Date Filing Date
SK2024-2000A SK20242000A3 (sk) 1998-07-02 1999-06-30 Paroxetínová soľ, spôsob jej prípravy a jej použitie

Country Status (21)

Country Link
EP (1) EP1091958A1 (cs)
JP (1) JP2002519421A (cs)
KR (1) KR20010053337A (cs)
CN (1) CN1314906A (cs)
AP (1) AP2000002017A0 (cs)
AU (2) AU4903999A (cs)
BG (1) BG105204A (cs)
BR (1) BR9911679A (cs)
CA (1) CA2336470A1 (cs)
CZ (1) CZ20004923A3 (cs)
EA (1) EA200100098A1 (cs)
GB (1) GB9814316D0 (cs)
HU (1) HUP0103712A3 (cs)
ID (1) ID27766A (cs)
IL (1) IL140385A0 (cs)
NO (1) NO20006547L (cs)
PL (1) PL345365A1 (cs)
SK (1) SK20242000A3 (cs)
TR (1) TR200100055T2 (cs)
WO (1) WO2000001692A1 (cs)
ZA (2) ZA992899B (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1622630T1 (sl) 2003-05-07 2012-12-31 Osteologix A/S Stroncijeva kombinacije za profilakso/zdravljenje patologij hrustanca in/ali kosti
ES2275218T3 (es) 2003-05-07 2007-06-01 Osteologix A/S Sales de estroncio hidrosolubles para el tratamiento de afecciones de cartilagos y/o huesos.
KR101165614B1 (ko) 2004-02-26 2012-07-18 오스테올로지스 에이에스 괴사성 골 질환의 예방 또는 치료에 사용하기 위한스트론튬 함유 화합물
US7589235B2 (en) 2004-05-06 2009-09-15 Osteologix, A/S High yield and rapid synthesis methods for producing metallo-organic salts
KR100672184B1 (ko) 2004-09-21 2007-01-19 주식회사종근당 파록세틴의 콜린산 또는 콜린산 유도체 염
JP2010504281A (ja) * 2006-07-27 2010-02-12 エミスフェアー・テクノロジーズ・インク アリールスルファニル化合物、および活性薬剤を送達するための組成物
CN109212055B (zh) * 2018-08-19 2021-05-07 丁立平 一种测定饮用水中四种痕量单卤代苯乙酸的气相色谱-质谱联用法
CN109342633B (zh) * 2018-11-27 2020-10-02 北京市化工职业病防治院 尿液中苯、甲苯和二甲苯代谢物的检测方法
CN111337460B (zh) * 2018-12-18 2021-09-17 中国科学院大连化学物理研究所 一种高稳定性Halo-tag探针及其合成和生物应用
CN116283778B (zh) * 2023-02-23 2025-08-29 江苏理工学院 一种吡唑羧酸类化合物及其制备方法和应用
US20250091996A1 (en) 2023-09-15 2025-03-20 King Faisal University 2-(1h-imidazole-1-carbonyl)benzoic acid as an anticancer compound

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8430581D0 (en) * 1984-12-04 1985-01-09 Ferrosan As Treatment
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
CA2206592A1 (en) * 1996-05-30 1997-11-30 Shu-Zhong Wang Method of producing amorphous paroxetine hydrochloride
HU221921B1 (hu) * 1996-07-08 2003-02-28 Richter Gedeon Vegyészeti Gyár Rt. N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására
EE03970B1 (et) * 1997-06-10 2003-02-17 Synthon B.V. 4-fenüülpiperidiinühend, selle valmistamine ja kasutamine ning seda sisaldav ravim
CA2319652A1 (en) * 1998-02-06 1999-08-12 Michael Urquhart Salts of paroxetine

Also Published As

Publication number Publication date
GB9814316D0 (en) 1998-09-02
ZA992899B (en) 2000-03-29
JP2002519421A (ja) 2002-07-02
AP2000002017A0 (en) 2000-12-31
CZ20004923A3 (cs) 2001-08-15
HUP0103712A3 (en) 2002-09-30
IL140385A0 (en) 2002-02-10
PL345365A1 (en) 2001-12-17
AU2002100370A4 (en) 2002-06-06
NO20006547D0 (no) 2000-12-21
WO2000001692A1 (en) 2000-01-13
EP1091958A1 (en) 2001-04-18
NO20006547L (no) 2001-02-12
HUP0103712A2 (hu) 2002-05-29
AU4903999A (en) 2000-01-24
BR9911679A (pt) 2002-01-29
BG105204A (en) 2001-11-30
CN1314906A (zh) 2001-09-26
TR200100055T2 (tr) 2001-07-23
ZA200100020B (en) 2002-03-25
KR20010053337A (ko) 2001-06-25
CA2336470A1 (en) 2000-01-13
ID27766A (id) 2001-04-26
EA200100098A1 (ru) 2001-08-27

Similar Documents

Publication Publication Date Title
SU1097194A3 (ru) Способ получени производных феноксиалкилкарбоновой кислоты, а также их натриевых солей, сложных эфиров и амидов
AU4903999A (en) Salts of paroxetine
DE69527798T2 (de) Substituierte 4-biarylbutyr-oder 5-biarylpentasäuren und derivate als matrix metalloprotease inhibitoren
RU2529484C2 (ru) Ациламино-замещенные производные конденсированных циклопентанкарбоновых кислот и их применение в качестве фармацевтических средств
DE69514813T2 (de) Bicyclische diarylheterocyclen als cyclooxygenase-2-inhibitoren
CA2401778A1 (en) Benzamides and related inhibitors of factor xa
KR100938950B1 (ko) 치환 페닐 알칸산 유도체 및 그 용도
IE43142B1 (en) Phenylacetic acid derivatives
JP2010143937A (ja) 抗凝血薬として用いるクマリン誘導体
DE69023960T2 (de) Phenylalkan(en)säuren.
GB1476214A (en) Dibenzoxepin derivatives process for the preparation thereof and pharmaceutical compositions containing them
MXPA01000133A (en) Salts of paroxetine
SE9300013L (sv) Nytt förfarande och mellanprodukter för framställning av pro- läkemedel
KR100338999B1 (ko) 고지혈증치료제
JPH0278675A (ja) ベンゾフラニル酢酸誘導体、その製法、粘液調節剤および抗ヒスタミン剤
ES446691A1 (es) Procedimiento para la preparacion de nuevos acidos 3-(4-bi- fenilil)-butiricos, sus esteres y amidas.
KR20080015788A (ko) GlyR의 조정제 또는 아고니스트인 벤조산 유도체
PT83667B (pt) Processo para a preparacao de acidos e esteres {{{(3-piridinil)metileno}amino}oxi}-alcanoicos e de composicoes farmaceuticas que os contenham
WO2002004439A3 (en) Thiophene retinoids
JPH02124869A (ja) ロイコトリエン拮抗剤のエステルプロドラッグ
RU96119966A (ru) Производное хинола для лечения недержания мочи
DE68913159T2 (de) Thiophencarboxamid-Derivate und ihre Verwendung als Heilmittel.
EP0710665A1 (en) Phosphonosulfonate squalene synthetase inhibitor salts and method
JPS58201762A (ja) 3−カルボキシ−1,4−ジメチルピロ−ル−2−酢酸の製造方法
Thorpe et al. XXXVIII.—The αβ-dimethylglutaric acids, and the separation of cis-and trans-forms of substituted glutaric acids