SK278039B6 - 1-phenylimidazole derivative, method od its production and its use - Google Patents

1-phenylimidazole derivative, method od its production and its use Download PDF

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Publication number
SK278039B6
SK278039B6 SK440-91A SK44091A SK278039B6 SK 278039 B6 SK278039 B6 SK 278039B6 SK 44091 A SK44091 A SK 44091A SK 278039 B6 SK278039 B6 SK 278039B6
Authority
SK
Slovakia
Prior art keywords
imidazole
trifluoromethylphenyl
compound
tetrafluoroethyl
chloro
Prior art date
Application number
SK440-91A
Other languages
English (en)
Slovak (sk)
Inventor
Chemical Company Ltd Sumitomo
Original Assignee
Sumitomo Chemical Company Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Company Ltd. filed Critical Sumitomo Chemical Company Ltd.
Publication of SK278039B6 publication Critical patent/SK278039B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK440-91A 1990-06-29 1991-02-20 1-phenylimidazole derivative, method od its production and its use SK278039B6 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17313590 1990-06-29
JP23543990 1990-09-04

Publications (1)

Publication Number Publication Date
SK278039B6 true SK278039B6 (en) 1995-11-08

Family

ID=26495230

Family Applications (1)

Application Number Title Priority Date Filing Date
SK440-91A SK278039B6 (en) 1990-06-29 1991-02-20 1-phenylimidazole derivative, method od its production and its use

Country Status (14)

Country Link
US (2) US5153215A (cs)
EP (2) EP0464979B1 (cs)
KR (2) KR920000729A (cs)
AU (2) AU633183B2 (cs)
BR (2) BR9100663A (cs)
CA (2) CA2036148A1 (cs)
CZ (2) CZ279634B6 (cs)
DE (2) DE69103231T2 (cs)
ES (2) ES2057755T3 (cs)
HU (2) HUT58058A (cs)
IL (2) IL97279A (cs)
MY (2) MY104627A (cs)
SK (1) SK278039B6 (cs)
YU (2) YU30391A (cs)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
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MY106533A (en) * 1990-02-20 1995-06-30 Sumitomo Chemical Co A 4-tert.-butyl imidazole derivative and its production and use.
CA2036148A1 (en) * 1990-06-29 1991-12-30 Hiroki Tomioka A 1-phenylimidazole derivative and its production and use
US5252590A (en) * 1991-06-28 1993-10-12 Sumitomo Chemical Company, Limited 1-pyridylimidazole derivative
EP0599183A1 (en) * 1992-11-25 1994-06-01 Rhone-Poulenc Agrochimie Manufacturing of pesticides and intermediates
JP3715994B2 (ja) * 1993-12-21 2005-11-16 住友化学株式会社 害虫防除剤
US6413542B1 (en) 1996-03-29 2002-07-02 Merial Direct pour-on antiparasitic skin solution and methods for treating, preventing and controlling myasis
US6733767B2 (en) 1998-03-19 2004-05-11 Merck & Co., Inc. Liquid polymeric compositions for controlled release of bioactive substances
US6787342B2 (en) 2000-02-16 2004-09-07 Merial Limited Paste formulations
US20040077703A1 (en) * 2002-10-02 2004-04-22 Soll Mark D. Nodulisporic acid derivative spot-on formulations for combating parasites
US7262214B2 (en) 2003-02-26 2007-08-28 Merial Limited 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases
US7531186B2 (en) * 2003-12-17 2009-05-12 Merial Limited Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz
US20050234119A1 (en) * 2004-04-16 2005-10-20 Soll Mark D Antiparasitical agents and methods for treating, preventing and controlling external parasites in animals
US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
CN101511795B (zh) * 2006-07-05 2013-09-18 安万特农业公司 1-芳基-5-烷基吡唑衍生化合物、其制备方法和使用方法
AU2007281911B2 (en) * 2006-08-04 2014-02-06 Beth Israel Deaconess Medical Center Inhibitors of pyruvate kinase and methods of treating disease
US9173728B2 (en) 2008-11-19 2015-11-03 Merial Inc. Multi-cavity container having offset indentures for dispensing fluids
WO2010059529A2 (en) * 2008-11-19 2010-05-27 Merial Limited Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof
JP5756457B2 (ja) * 2009-04-06 2015-07-29 アジオス ファーマシューティカルズ， インコーポレイテッド ピルビン酸キナーゼｍ２調節剤、治療組成物および関連する使用方法
PL2427441T3 (pl) 2009-05-04 2017-06-30 Agios Pharmaceuticals, Inc. Aktywatory PKM2 do stosowania w leczeniu raka
PE20120693A1 (es) * 2009-06-29 2012-07-04 Agios Pharmaceuticals Inc Compuestos heterociclos como moduladores de la piruvato cinasa m2 (pkm2)
DK2448581T3 (en) 2009-06-29 2017-03-13 Agios Pharmaceuticals Inc Therapeutic compositions and methods for their applications
US8980896B2 (en) 2009-12-17 2015-03-17 Merial, Inc. Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
US9221792B2 (en) 2010-12-17 2015-12-29 Agios Pharmaceuticals, Inc N-(4-(azetidine-1-carbonyl) phenyl)-(hetero-) arylsulfonamide derivatives as pyruvate kinase M2 (PMK2) modulators
WO2012088314A1 (en) 2010-12-21 2012-06-28 Agios Pharmaceuticals, Inc. Bicyclic pkm2 activators
TWI549947B (zh) 2010-12-29 2016-09-21 阿吉歐斯製藥公司 治療化合物及組成物
PT3406251T (pt) 2011-05-03 2024-01-24 Agios Pharmaceuticals Inc Ativadores da piruvato-cinase para utilização em terapia
WO2012151440A1 (en) 2011-05-03 2012-11-08 Agios Pharmaceuticals, Inc. Pyruvate kinase activators for use for increasing lifetime of the red blood cells and treating anemia
CA2855954C (en) 2011-11-17 2020-09-01 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof.
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
TWI579274B (zh) 2012-04-20 2017-04-21 龍馬躍公司 製備１－芳基－５－烷基吡唑化合物的改良方法
WO2014139144A1 (en) 2013-03-15 2014-09-18 Agios Pharmaceuticals, Inc. Therapeutic compounds and compositions
AU2015339096B2 (en) 2014-10-31 2018-08-02 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal composition comprising fipronil
MX384883B (es) 2015-06-11 2025-03-14 Agios Pharmaceuticals Inc Métodos para usar activadores de piruvato cinasa.

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3940484A (en) * 1971-12-07 1976-02-24 The Boots Company Limited Insecticidal compositions and methods of combatting insects using substituted imidazoles
US3996366A (en) * 1973-11-19 1976-12-07 The Boots Company Limited Thio derivatives of imidazol-1-yl carboxamides
US4048188A (en) * 1971-12-07 1977-09-13 The Boots Company Limited 1-Carbonamido imidazoles
GB1408877A (en) * 1971-12-07 1975-10-08 Boots Co Ltd Substituted imidazoles and their use as pesticides
SE447653B (sv) * 1978-11-14 1986-12-01 Eisai Co Ltd Imidazolderivat samt farmaceutisk komposition innehallande sadant derivat
US4600430A (en) * 1985-02-22 1986-07-15 Eli Lilly And Company Pyridinylimidazolidinone compounds
US4634711A (en) * 1985-08-02 1987-01-06 Smithkline Beckman Corporation Pyridylalkyl imidazole-2-thiols
DE3614364A1 (de) * 1986-04-28 1987-10-29 Hoechst Ag 1-phenyl-imidazolverbindungen, verfahren zu ihrer herstellung und ihre verwendung als wachstumsregulatoren
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
FI91754C (fi) * 1986-12-02 1994-08-10 Tanabe Seiyaku Co Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi
DE3811574A1 (de) * 1988-03-31 1989-10-19 Schering Ag N-substituierte imidazole, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
CA2015366C (en) * 1989-05-05 2001-09-11 Rhone-Poulenc Agrochimie Pesticidal 1-arylimidazoles
MY106533A (en) * 1990-02-20 1995-06-30 Sumitomo Chemical Co A 4-tert.-butyl imidazole derivative and its production and use.
CA2036148A1 (en) * 1990-06-29 1991-12-30 Hiroki Tomioka A 1-phenylimidazole derivative and its production and use

Also Published As

Publication number Publication date
AU7118891A (en) 1992-01-02
AU633184B2 (en) 1993-01-21
AU633183B2 (en) 1993-01-21
BR9100662A (pt) 1992-04-07
HU910548D0 (en) 1991-09-30
CZ279536B6 (cs) 1995-05-17
MY104627A (en) 1994-04-30
HU910549D0 (en) 1991-09-30
MY104626A (en) 1994-04-30
HUT58059A (en) 1992-01-28
EP0464979A1 (en) 1992-01-08
ES2057754T3 (es) 1994-10-16
BR9100663A (pt) 1992-04-07
YU30391A (sh) 1994-01-20
KR920000729A (ko) 1992-01-29
HUT58058A (en) 1992-01-28
EP0464979B1 (en) 1994-08-03
IL97279A (en) 1994-12-29
DE69103230D1 (de) 1994-09-08
AU7118691A (en) 1992-01-02
HU206951B (en) 1993-03-01
EP0464980B1 (en) 1994-08-03
DE69103231T2 (de) 1994-12-15
CA2036147A1 (en) 1991-12-30
YU30491A (sh) 1994-01-20
IL97279A0 (en) 1992-05-25
DE69103230T2 (de) 1994-12-01
CS44191A3 (en) 1992-02-19
KR920000745A (ko) 1992-01-29
US5122530A (en) 1992-06-16
CS44091A3 (en) 1992-02-19
US5153215A (en) 1992-10-06
IL97278A0 (en) 1992-05-25
ES2057755T3 (es) 1994-10-16
DE69103231D1 (de) 1994-09-08
CZ279634B6 (cs) 1995-05-17
EP0464980A1 (en) 1992-01-08
CA2036148A1 (en) 1991-12-30

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