SK278470B6 - 10(1-hydroxyethyl)-11-oxo-1-azatricyclo£7.2.0.0exp(3.8)|undec-2- -ene-2-carboxylic acid esters, a process for preparing thereof and pharmaceutical compositions containing them - Google Patents

10(1-hydroxyethyl)-11-oxo-1-azatricyclo£7.2.0.0exp(3.8)|undec-2- -ene-2-carboxylic acid esters, a process for preparing thereof and pharmaceutical compositions containing them Download PDF

Info

Publication number: SK278470B6
Authority: SK; Slovakia
Prior art keywords: alkyl; methoxy; formula; group; oxo
Prior art date: 1990-08-21

Application number

SK1213-92A

Other languages

English (en)

Slovak (sk)

Other versions

SK121392A3 (en

Inventor

Alcide Perboni

Tino Rossi

Giovanni Gaviraghi

Antonella Ursini

Giorgio Tarzia

Original Assignee

Alcide Perboni

Tino Rossi

Giovanni Gaviraghi

Antonella Ursini

Giorgio Tarzia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-21

Filing date

1991-08-20

Publication date

1997-06-04

1990-08-21 Priority claimed from GB909018330A external-priority patent/GB9018330D0/en

1991-03-07 Priority claimed from GB919104770A external-priority patent/GB9104770D0/en

1991-08-20 Application filed by Alcide Perboni, Tino Rossi, Giovanni Gaviraghi, Antonella Ursini, Giorgio Tarzia filed Critical Alcide Perboni

1997-06-04 Publication of SK121392A3 publication Critical patent/SK121392A3/sk

1997-06-04 Publication of SK278470B6 publication Critical patent/SK278470B6/sk

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)
Heat Sensitive Colour Forming Recording (AREA)

SK1213-92A 1990-08-21 1991-08-20 10(1-hydroxyethyl)-11-oxo-1-azatricyclo£7.2.0.0exp(3.8)|undec-2- -ene-2-carboxylic acid esters, a process for preparing thereof and pharmaceutical compositions containing them SK278470B6 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB909018330A GB9018330D0 (en)	1990-08-21	1990-08-21	Heterocyclic compounds
GB919104770A GB9104770D0 (en)	1991-03-07	1991-03-07	Heterocyclic compounds
PCT/EP1991/001589 WO1992003437A1 (en)	1990-08-21	1991-08-20	10(1-hydroxyethyl)-11-oxo-1-azatricyclo[7.2.0.0.3.8]undec-2-ene-2-carboxylic acid esters and a process for preparing thereof

Publications (2)

Publication Number	Publication Date
SK121392A3 SK121392A3 (en)	1997-06-04
SK278470B6 true SK278470B6 (en)	1997-06-04

Family

ID=26297540

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1213-92A SK278470B6 (en)	1990-08-21	1991-08-20	10(1-hydroxyethyl)-11-oxo-1-azatricyclo£7.2.0.0exp(3.8)\|undec-2- -ene-2-carboxylic acid esters, a process for preparing thereof and pharmaceutical compositions containing them

Country Status (32)

Country	Link
US (1)	US5587374A (de)
EP (1)	EP0495953B1 (de)
JP (2)	JP3151215B2 (de)
KR (1)	KR0169147B1 (de)
CN (1)	CN1030917C (de)
AP (1)	AP238A (de)
AT (1)	ATE106887T1 (de)
AU (1)	AU647178B2 (de)
CA (1)	CA2067741C (de)
CY (1)	CY2037A (de)
CZ (1)	CZ280942B6 (de)
DE (1)	DE69102415T2 (de)
DK (1)	DK0495953T3 (de)
ES (1)	ES2054502T3 (de)
FI (1)	FI97136C (de)
HK (1)	HK19495A (de)
HR (1)	HRP940556B1 (de)
HU (2)	HUT61024A (de)
IE (1)	IE66122B1 (de)
IL (1)	IL99248A (de)
MX (1)	MX9100743A (de)
MY (1)	MY106997A (de)
NO (1)	NO300176B1 (de)
NZ (1)	NZ239474A (de)
OA (1)	OA09578A (de)
PL (1)	PL169425B1 (de)
PT (1)	PT98729B (de)
SG (1)	SG169494G (de)
SI (1)	SI9111427B (de)
SK (1)	SK278470B6 (de)
WO (1)	WO1992003437A1 (de)
YU (1)	YU48079B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9104838D0 (en) *	1991-03-07	1991-04-17	Glaxo Spa	Heterocyclic compounds
AP294A (en) *	1992-08-31	1993-12-28	Glaxo Spa	"10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo-(7.2.0.0.3.8) undec-2-ene-2-carboxylic acid derivatives".
GB9218781D0 (en) *	1992-09-04	1992-10-21	Glaxo Spa	Heterocyclic derivatives
IN188720B (de) *	1997-11-06	2002-11-02	Panacea Biotec Ltd
JP4377231B2 (ja) *	2001-11-05	2009-12-02	大日本住友製薬株式会社	新規なカルバペネム化合物
JPWO2004089954A1 (ja) *	2003-04-08	2006-07-06	大日本住友製薬株式会社	新規なカルバペネム化合物
JPWO2006025475A1 (ja) *	2004-09-03	2008-05-08	大日本住友製薬株式会社	新規なカルバペネム化合物
WO2006103999A1 (ja) *	2005-03-25	2006-10-05	Dainippon Sumitomo Pharma Co., Ltd.	新規なカルバペネム化合物
EP2085084A1 (de)	2008-01-29	2009-08-05	LEK Pharmaceuticals D.D.	Verwendung eines Hemmers von Beta-Lactamasen und dessen Kombination mit Beta-Lactam-Antibiotika
EP2135871A1 (de) *	2008-06-18	2009-12-23	LEK Pharmaceuticals D.D.	Neuartige Trinemantibiotika und Hemmer von Beta-Lactamasen
RS63461B1 (sr)	2017-05-08	2022-08-31	Glaxosmithkline Ip Dev Ltd	Sanfetrinem ili njegova so ili estar za upotrebu u lečenju mikobakterijske infekcije

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1425571A (en) *	1972-03-13	1976-02-18	Astra Laekemedel Ab	Penicillins and cephaosporins
GB1433131A (en) *	1972-03-13	1976-04-22	Astra Laekemedel Ab	Penicillins
DE2811514A1 (de) *	1977-03-19	1978-09-21	Beecham Group Ltd	Ester der 7-oxo-1-azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept- 2-en-2-carbonsaeure und deren derivate, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zubereitungen
US4374848A (en) *	1981-09-14	1983-02-22	Merck & Co., Inc.	6-(1-Hydroxyethyl)cyclonocardicin
US4374849A (en) *	1981-09-14	1983-02-22	Merck & Co., Inc.	6-Amidocyclonocardicins
CZ435990A3 (cs) *	1989-09-08	1999-11-17	Glaxo S.P.A.	Kyselina 10-(1-hydroxyethyl)-11-oxo-1-azatricyklo/7,2,0,03,8/-undec-2en-2-karboxylová a její deriváty, způsob jejich výroby, použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem
AU636913B2 (en) *	1989-10-11	1993-05-13	Takeda Chemical Industries Ltd.	Tricyclic carbapenem compounds
GB9104832D0 (en) *	1991-03-07	1991-04-17	Glaxo Spa	Heterocyclic compounds
GB9104838D0 (en) *	1991-03-07	1991-04-17	Glaxo Spa	Heterocyclic compounds

1991
- 1991-08-20 JP JP51366091A patent/JP3151215B2/ja not_active Expired - Fee Related
- 1991-08-20 CA CA002067741A patent/CA2067741C/en not_active Expired - Fee Related
- 1991-08-20 SK SK1213-92A patent/SK278470B6/sk unknown
- 1991-08-20 MX MX9100743A patent/MX9100743A/es unknown
- 1991-08-20 PL PL91294573A patent/PL169425B1/pl unknown
- 1991-08-20 WO PCT/EP1991/001589 patent/WO1992003437A1/en not_active Ceased
- 1991-08-20 HU HU921303A patent/HUT61024A/hu unknown
- 1991-08-20 IL IL9924891A patent/IL99248A/en not_active IP Right Cessation
- 1991-08-20 CN CN91109093A patent/CN1030917C/zh not_active Expired - Fee Related
- 1991-08-20 PT PT98729A patent/PT98729B/pt not_active IP Right Cessation
- 1991-08-20 AT AT91914351T patent/ATE106887T1/de not_active IP Right Cessation
- 1991-08-20 ES ES91914351T patent/ES2054502T3/es not_active Expired - Lifetime
- 1991-08-20 AU AU84212/91A patent/AU647178B2/en not_active Ceased
- 1991-08-20 CZ CS921213A patent/CZ280942B6/cs not_active IP Right Cessation
- 1991-08-20 EP EP91914351A patent/EP0495953B1/de not_active Expired - Lifetime
- 1991-08-20 DK DK91914351.1T patent/DK0495953T3/da active
- 1991-08-20 YU YU142791A patent/YU48079B/sh unknown
- 1991-08-20 SI SI9111427A patent/SI9111427B/sl unknown
- 1991-08-20 MY MYPI91001514A patent/MY106997A/en unknown
- 1991-08-20 DE DE69102415T patent/DE69102415T2/de not_active Expired - Fee Related
- 1991-08-20 NZ NZ239474A patent/NZ239474A/en unknown
- 1991-08-20 AP APAP/P/1991/000320A patent/AP238A/en active
- 1991-08-20 IE IE294491A patent/IE66122B1/en not_active IP Right Cessation
1992
- 1992-04-13 OA OA60190A patent/OA09578A/en unknown
- 1992-04-15 NO NO921521A patent/NO300176B1/no unknown
- 1992-04-16 FI FI921717A patent/FI97136C/fi active
- 1992-04-20 KR KR1019920700916A patent/KR0169147B1/ko not_active Expired - Fee Related
1994
- 1994-09-16 HR HR940556A patent/HRP940556B1/xx not_active IP Right Cessation
- 1994-12-01 SG SG169494A patent/SG169494G/en unknown
1995
- 1995-02-09 HK HK19495A patent/HK19495A/en not_active IP Right Cessation
- 1995-02-14 US US08/388,515 patent/US5587374A/en not_active Expired - Fee Related
- 1995-06-27 HU HU95P/P00455P patent/HU211584A9/hu unknown
1998
- 1998-02-20 CY CY203798A patent/CY2037A/xx unknown
2000
- 2000-05-17 JP JP2000144232A patent/JP3461786B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2067741A1 (en)	1992-02-22
OA09578A (en)	1993-01-31
IE912944A1 (en)	1992-02-26
HRP940556A2 (en)	1996-06-30
IE66122B1 (en)	1995-12-13
KR0169147B1 (en)	1999-01-15
HRP940556B1 (en)	2000-06-30
ES2054502T3 (es)	1994-08-01
SK121392A3 (en)	1997-06-04
HK19495A (en)	1995-02-17
NO300176B1 (no)	1997-04-21
PT98729B (pt)	1999-01-29
HU211584A9 (en)	1995-12-28
MX9100743A (es)	1992-04-01
FI921717A0 (fi)	1992-04-16
DK0495953T3 (da)	1994-07-18
JP3461786B2 (ja)	2003-10-27
PL169425B1 (pl)	1996-07-31
SG169494G (en)	1995-04-28
JP3151215B2 (ja)	2001-04-03
HU9201303D0 (en)	1992-07-28
MY106997A (en)	1995-08-30
AU8421291A (en)	1992-03-17
FI97136C (fi)	1996-10-25
SI9111427B (sl)	2000-10-31
SI9111427A (en)	1996-12-31
ATE106887T1 (de)	1994-06-15
YU142791A (sh)	1994-01-20
FI921717L (fi)	1992-04-16
CY2037A (en)	1998-02-20
CZ280942B6 (cs)	1996-05-15
DE69102415D1 (de)	1994-07-14
DE69102415T2 (de)	1994-10-13
JP2000351730A (ja)	2000-12-19
FI97136B (fi)	1996-07-15
AU647178B2 (en)	1994-03-17
CZ121392A3 (en)	1993-04-14
WO1992003437A1 (en)	1992-03-05
JPH05502044A (ja)	1993-04-15
NO921521L (no)	1992-06-22
CA2067741C (en)	2002-01-01
CN1060094A (zh)	1992-04-08
AP9100320A0 (en)	1991-10-31
NO921521D0 (no)	1992-04-15
EP0495953A1 (de)	1992-07-29
IL99248A0 (en)	1992-07-15
YU48079B (sh)	1997-01-08
KR920702361A (ko)	1992-09-03
HUT61024A (en)	1992-11-30
CN1030917C (zh)	1996-02-07
NZ239474A (en)	1994-06-27
PT98729A (pt)	1992-07-31
IL99248A (en)	1996-01-31
EP0495953B1 (de)	1994-06-08
AP238A (en)	1993-02-04
US5587374A (en)	1996-12-24

Publication	Publication Date	Title
US4260627A (en)	1981-04-07	1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids
US5892099A (en)	1999-04-06	3,7-dithiaprostanoic acid derivative
US4465632A (en)	1984-08-14	Process for preparing 1-6-and 2-substituted-1-carba-2-penem-3-carboxylic acids
CH685630A5 (fr)	1995-08-31	Dérivés de l'indole.
SK278688B6 (sk)	1998-01-14	Kyselina 10-(1-hydroxyetyl)-11-oxo-1-azatricyklo[7
SK278470B6 (en)	1997-06-04	10(1-hydroxyethyl)-11-oxo-1-azatricyclo£7.2.0.0exp(3.8)\|undec-2- -ene-2-carboxylic acid esters, a process for preparing thereof and pharmaceutical compositions containing them
US4859698A (en)	1989-08-22	Novel class of acyl-derivatives of carnitine, process for preparing same and therapeutic use thereof
US4348320A (en)	1982-09-07	Substituted azetidiones
AU593874B2 (en)	1990-02-22	2-heterocyclylthio penems
CH640236A5 (en)	1983-12-30	3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2 -carboxylic acid and process for its preparation
JPH06505018A (ja)	1994-06-09	複素環式化合物
RU2043354C1 (ru)	1995-09-10	Эфиры 10(1- гидроксиэтил) -11-оксо-1-азатрицикло [7,2,0,03,8]ундец-2-ен-2-карбоновой кислоты и способ их получения
EP0502465A1 (de)	1992-09-09	Ester von antibakteriellen kondensierten Carbapenemderivaten
FR2526798A1 (fr)	1983-11-18	Derives de peneme, leur procede de preparation et compositions therapeutiques les contenant
CZ185193A3 (en)	1994-05-18	Heterocyclic derivatives, process of their preparation and pharmaceutical preparations in which they are comprised
FR2571054A1 (fr)	1986-04-04	Antibiotiques a base de carbapenem et leur procede de preparation
US4264621A (en)	1981-04-28	5-Substituted-3-(2-aminoethylthio)-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
JPH09510193A (ja)	1997-10-14	縮合カルバペネムのフェニルアルキルアミノ誘導体
FR2505842A1 (fr)	1982-11-19	Nouveaux derives de la tetrahydro-2,3,6,7 thiazolo (3,2-a) pyrimidinone-5, leur preparation et les medicaments qui les contiennent