SK281815B6 - Derivát oxazolidinónu, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje - Google Patents
Derivát oxazolidinónu, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje Download PDFInfo
- Publication number
- SK281815B6 SK281815B6 SK1368-95A SK136895A SK281815B6 SK 281815 B6 SK281815 B6 SK 281815B6 SK 136895 A SK136895 A SK 136895A SK 281815 B6 SK281815 B6 SK 281815B6
- Authority
- SK
- Slovakia
- Prior art keywords
- piperazino
- methyloxazolidin
- piperidyl
- amidino
- piperazinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4439846A DE4439846A1 (de) | 1994-11-08 | 1994-11-08 | Adhäsionsrezeptor-Antagonisten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK136895A3 SK136895A3 (en) | 1996-06-05 |
| SK281815B6 true SK281815B6 (sk) | 2001-08-06 |
Family
ID=6532768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1368-95A SK281815B6 (sk) | 1994-11-08 | 1995-11-02 | Derivát oxazolidinónu, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5776937A (pl) |
| EP (1) | EP0711770A1 (pl) |
| JP (1) | JPH08208629A (pl) |
| KR (1) | KR100384978B1 (pl) |
| CN (1) | CN1069640C (pl) |
| AR (1) | AR002245A1 (pl) |
| AU (1) | AU704184B2 (pl) |
| BR (1) | BR9505109A (pl) |
| CA (1) | CA2162223A1 (pl) |
| CO (1) | CO4520229A1 (pl) |
| CZ (1) | CZ291049B6 (pl) |
| DE (1) | DE4439846A1 (pl) |
| FI (1) | FI955351L (pl) |
| HU (1) | HU217085B (pl) |
| NO (1) | NO306113B1 (pl) |
| PL (1) | PL183595B1 (pl) |
| RU (1) | RU2155762C2 (pl) |
| SK (1) | SK281815B6 (pl) |
| TR (1) | TR199501389A2 (pl) |
| TW (1) | TW316903B (pl) |
| UA (1) | UA41928C2 (pl) |
| ZA (1) | ZA959434B (pl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4332384A1 (de) * | 1993-09-23 | 1995-03-30 | Merck Patent Gmbh | Adhäsionsrezeptor-Antagonisten III |
| ATE170179T1 (de) * | 1994-11-02 | 1998-09-15 | Merck Patent Gmbh | Adhäsionsrezeptor-antagonisten |
| US6046331A (en) * | 1998-12-17 | 2000-04-04 | Synaptic Pharmaceutical Corporation | Imidazolones and their use in treating benign prostatic hyperplasia and other disorders |
| CN1398189A (zh) | 1998-12-23 | 2003-02-19 | G.D.西尔公司 | 用于治疗肿瘤形成的放疗与cox－2抑制剂的联合治疗 |
| EP1147422A1 (en) | 1999-01-27 | 2001-10-24 | Pharmacia & Upjohn Company | Assays for modulators of "elongation factor p" activity |
| MXPA04007067A (es) * | 2002-01-22 | 2004-11-01 | Upjohn Co | Dispositivos medicos resistentes a infecciones. |
| WO2004032856A2 (en) * | 2002-10-07 | 2004-04-22 | Smithkline Beecham Corporation | Compounds |
| TWI341312B (en) * | 2002-12-24 | 2011-05-01 | Sankyo Co | Optical active dihydropyridine derivatives |
| CN102796091A (zh) * | 2011-05-24 | 2012-11-28 | 北大方正集团有限公司 | 取代的噁唑烷酮化合物及其制备方法和应用 |
| IN2015DN00961A (pl) * | 2012-10-29 | 2015-06-12 | Hoffmann La Roche | |
| CN104230915B (zh) * | 2014-08-29 | 2016-08-17 | 南京大学 | 含噻唑烷二酮的苯基哌嗪衍生物及其制备方法与用途 |
| WO2018236745A1 (en) | 2017-06-20 | 2018-12-27 | Carnot, Llc | COMPOSITIONS AND METHODS FOR INCREASING THE EFFICACY OF CARDIAC METABOLISM |
| EP4497474A3 (en) | 2018-10-17 | 2025-04-23 | Imbria Pharmaceuticals, Inc. | Methods of treating rheumatic diseases using trimetazidine-based compounds |
| EP3976101A4 (en) | 2019-05-31 | 2023-06-21 | Imbria Pharmaceuticals, Inc. | FIBROSIS TREATMENT METHODS USING COMPOUNDS THAT PROMOTE GLUCOSE OXIDATION |
| US11780811B2 (en) | 2020-06-30 | 2023-10-10 | Imbria Pharmaceuticals, Inc. | Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11530184B2 (en) | 2020-06-30 | 2022-12-20 | Imbria Pharmaceuticals, Inc. | Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11883396B2 (en) | 2021-05-03 | 2024-01-30 | Imbria Pharmaceuticals, Inc. | Methods of treating kidney conditions using modified forms of trimetazidine |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3723797A1 (de) * | 1987-07-18 | 1989-01-26 | Merck Patent Gmbh | Oxazolidinone |
| US5053393A (en) * | 1988-07-20 | 1991-10-01 | Monsanto Company | Novel platelet-aggregation inhibitor |
| US4948801A (en) * | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
| DE4005371A1 (de) * | 1990-02-21 | 1991-08-22 | Merck Patent Gmbh | Oxazolidinone |
| DE4017211A1 (de) * | 1990-05-29 | 1991-12-05 | Merck Patent Gmbh | Oxazolidinone |
| DE4405633A1 (de) * | 1993-05-01 | 1994-11-03 | Merck Patent Gmbh | Adhäsionsrezeptor-Antagonisten |
| ATE181735T1 (de) * | 1993-05-01 | 1999-07-15 | Merck Patent Gmbh | Substituierte 1-phenyl-oxazolidin-2-on derivate, deren herstellung und deren verwendung als adhäsionsrezeptor-antagonisten |
| DE4332384A1 (de) * | 1993-09-23 | 1995-03-30 | Merck Patent Gmbh | Adhäsionsrezeptor-Antagonisten III |
-
1994
- 1994-11-08 DE DE4439846A patent/DE4439846A1/de not_active Withdrawn
-
1995
- 1995-10-26 EP EP95116889A patent/EP0711770A1/de not_active Withdrawn
- 1995-11-01 UA UA95114761A patent/UA41928C2/uk unknown
- 1995-11-02 SK SK1368-95A patent/SK281815B6/sk unknown
- 1995-11-02 AU AU36618/95A patent/AU704184B2/en not_active Ceased
- 1995-11-06 CA CA002162223A patent/CA2162223A1/en not_active Abandoned
- 1995-11-06 TW TW084111748A patent/TW316903B/zh active
- 1995-11-06 CZ CZ19952888A patent/CZ291049B6/cs not_active IP Right Cessation
- 1995-11-07 CN CN95118753A patent/CN1069640C/zh not_active Expired - Fee Related
- 1995-11-07 US US08/551,743 patent/US5776937A/en not_active Expired - Fee Related
- 1995-11-07 NO NO954458A patent/NO306113B1/no not_active IP Right Cessation
- 1995-11-07 FI FI955351A patent/FI955351L/fi not_active IP Right Cessation
- 1995-11-07 PL PL95311257A patent/PL183595B1/pl not_active IP Right Cessation
- 1995-11-07 KR KR1019950040017A patent/KR100384978B1/ko not_active Expired - Fee Related
- 1995-11-07 ZA ZA959434A patent/ZA959434B/xx unknown
- 1995-11-07 HU HU9503191A patent/HU217085B/hu not_active IP Right Cessation
- 1995-11-07 BR BR9505109A patent/BR9505109A/pt not_active IP Right Cessation
- 1995-11-08 AR ARP950100091A patent/AR002245A1/es unknown
- 1995-11-08 RU RU95119427/04A patent/RU2155762C2/ru not_active IP Right Cessation
- 1995-11-08 JP JP7313684A patent/JPH08208629A/ja active Pending
- 1995-11-08 CO CO95052761A patent/CO4520229A1/es unknown
- 1995-11-08 TR TR95/01389A patent/TR199501389A2/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR002245A1 (es) | 1998-03-11 |
| TR199501389A2 (tr) | 1996-07-21 |
| FI955351A0 (fi) | 1995-11-07 |
| TW316903B (pl) | 1997-10-01 |
| BR9505109A (pt) | 1997-09-09 |
| CA2162223A1 (en) | 1996-05-09 |
| KR960017663A (ko) | 1996-06-17 |
| HUT76052A (en) | 1997-06-30 |
| FI955351A7 (fi) | 1996-05-09 |
| ZA959434B (en) | 1996-05-15 |
| SK136895A3 (en) | 1996-06-05 |
| AU704184B2 (en) | 1999-04-15 |
| NO954458L (no) | 1996-05-09 |
| RU2155762C2 (ru) | 2000-09-10 |
| US5776937A (en) | 1998-07-07 |
| CO4520229A1 (es) | 1997-10-15 |
| CN1132201A (zh) | 1996-10-02 |
| CZ288895A3 (en) | 1996-06-12 |
| UA41928C2 (uk) | 2001-10-15 |
| CN1069640C (zh) | 2001-08-15 |
| CZ291049B6 (cs) | 2002-12-11 |
| EP0711770A1 (de) | 1996-05-15 |
| PL311257A1 (en) | 1996-05-13 |
| DE4439846A1 (de) | 1996-05-09 |
| NO954458D0 (no) | 1995-11-07 |
| AU3661895A (en) | 1996-05-23 |
| HU9503191D0 (en) | 1996-01-29 |
| HU217085B (hu) | 1999-11-29 |
| KR100384978B1 (ko) | 2003-09-02 |
| NO306113B1 (no) | 1999-09-20 |
| JPH08208629A (ja) | 1996-08-13 |
| FI955351L (fi) | 1996-05-09 |
| PL183595B1 (pl) | 2002-06-28 |
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