SK4262003A3 - Tooth whitening composition and method employing dicarboxylic acid whitening agent - Google Patents

Tooth whitening composition and method employing dicarboxylic acid whitening agent Download PDF

Info

Publication number: SK4262003A3
Authority: SK; Slovakia
Prior art keywords: composition; acid; group; teeth; menthol
Prior art date: 2000-10-11

Application number

SK426-2003A

Other languages

English (en)

Slovak (sk)

Inventor

Constantine Argy Georgiades

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-11

Filing date

2001-10-03

Publication date

2003-11-04

2001-10-03 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2003-11-04 Publication of SK4262003A3 publication Critical patent/SK4262003A3/sk

Links

239000000203 mixture Substances 0.000 title claims abstract description 116
230000002087 whitening effect Effects 0.000 title claims abstract description 22
OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 title claims abstract description 19
239000003795 chemical substances by application Substances 0.000 title abstract description 13
238000000034 method Methods 0.000 title description 22
MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims abstract description 41
OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 claims abstract description 30
NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 20
229940041616 menthol Drugs 0.000 claims abstract description 20
150000003839 salts Chemical class 0.000 claims abstract description 20
239000000341 volatile oil Substances 0.000 claims abstract description 18
239000005844 Thymol Substances 0.000 claims abstract description 16
229960000790 thymol Drugs 0.000 claims abstract description 16
WEEGYLXZBRQIMU-UHFFFAOYSA-N 1,8-cineole Natural products C1CC2CCC1(C)OC2(C)C WEEGYLXZBRQIMU-UHFFFAOYSA-N 0.000 claims abstract description 15
WEEGYLXZBRQIMU-WAAGHKOSSA-N Eucalyptol Chemical compound C1C[C@H]2CC[C@]1(C)OC2(C)C WEEGYLXZBRQIMU-WAAGHKOSSA-N 0.000 claims abstract description 15
229960005233 cineole Drugs 0.000 claims abstract description 15
229960001047 methyl salicylate Drugs 0.000 claims abstract description 15
FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims abstract description 6
239000011975 tartaric acid Substances 0.000 claims abstract description 6
235000002906 tartaric acid Nutrition 0.000 claims abstract description 6
FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims abstract description 3
NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract 5
MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 89
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 33
235000006408 oxalic acid Nutrition 0.000 claims description 28
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 19
239000007844 bleaching agent Substances 0.000 claims description 16
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
-1 dicarboxylic acids dicarboxylic acids Chemical class 0.000 claims description 12
150000001991 dicarboxylic acids Chemical class 0.000 claims description 10
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IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims description 7
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 7
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239000006172 buffering agent Substances 0.000 claims description 4
238000004042 decolorization Methods 0.000 claims description 4
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims description 4
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GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims description 3
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244000166124 Eucalyptus globulus Species 0.000 claims 1
239000002324 mouth wash Substances 0.000 abstract description 41
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JPJBEORAVWZJKS-UHFFFAOYSA-N oxalic acid;propanedioic acid Chemical compound OC(=O)C(O)=O.OC(=O)CC(O)=O JPJBEORAVWZJKS-UHFFFAOYSA-N 0.000 abstract 1
239000000243 solution Substances 0.000 description 23
NOOLISFMXDJSKH-KXUCPTDWSA-N (-)-Menthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O NOOLISFMXDJSKH-KXUCPTDWSA-N 0.000 description 16
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NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 6
239000002585 base Substances 0.000 description 6
125000002091 cationic group Chemical group 0.000 description 6
239000000551 dentifrice Substances 0.000 description 6
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210000000214 mouth Anatomy 0.000 description 5
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208000006558 Dental Calculus Diseases 0.000 description 4
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DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 4
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
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239000003638 chemical reducing agent Substances 0.000 description 4
239000003086 colorant Substances 0.000 description 4
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210000004268 dentin Anatomy 0.000 description 4
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BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 4
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KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 4
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 4
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QMMFVYPAHWMCMS-UHFFFAOYSA-N Dimethyl sulfide Chemical compound CSC QMMFVYPAHWMCMS-UHFFFAOYSA-N 0.000 description 3
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206010061218 Inflammation Diseases 0.000 description 3
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VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
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CQAIPTBBCVQRMD-UHFFFAOYSA-L dipotassium;phosphono phosphate Chemical compound [K+].[K+].OP(O)(=O)OP([O-])([O-])=O CQAIPTBBCVQRMD-UHFFFAOYSA-L 0.000 description 3
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108040007629 peroxidase activity proteins Proteins 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
XMGMFRIEKMMMSU-UHFFFAOYSA-N phenylmethylbenzene Chemical group C=1C=CC=CC=1[C]C1=CC=CC=C1 XMGMFRIEKMMMSU-UHFFFAOYSA-N 0.000 description 1
239000000467 phytic acid Substances 0.000 description 1
235000002949 phytic acid Nutrition 0.000 description 1
229940068041 phytic acid Drugs 0.000 description 1
239000000049 pigment Substances 0.000 description 1
229920000728 polyester Polymers 0.000 description 1
229920001225 polyester resin Polymers 0.000 description 1
239000004645 polyester resin Substances 0.000 description 1
235000013824 polyphenols Nutrition 0.000 description 1
239000001205 polyphosphate Substances 0.000 description 1
235000011176 polyphosphates Nutrition 0.000 description 1
229920001282 polysaccharide Polymers 0.000 description 1
239000005017 polysaccharide Substances 0.000 description 1
229920000136 polysorbate Polymers 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
239000011591 potassium Substances 0.000 description 1
OQZCJRJRGMMSGK-UHFFFAOYSA-M potassium metaphosphate Chemical compound [K+].[O-]P(=O)=O OQZCJRJRGMMSGK-UHFFFAOYSA-M 0.000 description 1
229940099402 potassium metaphosphate Drugs 0.000 description 1
239000002244 precipitate Substances 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
PFGGBVOALJVMTI-UHFFFAOYSA-N prop-1-ene-1,2,3-tricarboxylic acid Chemical compound OC(=O)CC(C(O)=O)=CC(O)=O.OC(=O)CC(C(O)=O)=CC(O)=O PFGGBVOALJVMTI-UHFFFAOYSA-N 0.000 description 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
229960004063 propylene glycol Drugs 0.000 description 1
235000013772 propylene glycol Nutrition 0.000 description 1
150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
235000020095 red wine Nutrition 0.000 description 1
230000002040 relaxant effect Effects 0.000 description 1
239000011347 resin Substances 0.000 description 1
229920005989 resin Polymers 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
239000012047 saturated solution Substances 0.000 description 1
229960004029 silicic acid Drugs 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
BHZOKUMUHVTPBX-UHFFFAOYSA-M sodium acetic acid acetate Chemical compound [Na+].CC(O)=O.CC([O-])=O BHZOKUMUHVTPBX-UHFFFAOYSA-M 0.000 description 1
239000001509 sodium citrate Chemical class 0.000 description 1
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical class O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 description 1
229960004711 sodium monofluorophosphate Drugs 0.000 description 1
159000000000 sodium salts Chemical class 0.000 description 1
BFXAWOHHDUIALU-UHFFFAOYSA-M sodium;hydron;difluoride Chemical compound F.[F-].[Na+] BFXAWOHHDUIALU-UHFFFAOYSA-M 0.000 description 1
239000001593 sorbitan monooleate Substances 0.000 description 1
235000011069 sorbitan monooleate Nutrition 0.000 description 1
229940035049 sorbitan monooleate Drugs 0.000 description 1
238000005507 spraying Methods 0.000 description 1
239000005315 stained glass Substances 0.000 description 1
238000007447 staining method Methods 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
238000003756 stirring Methods 0.000 description 1
239000004575 stone Substances 0.000 description 1
KQAGKTURZUKUCH-UHFFFAOYSA-L strontium oxalate Chemical compound [Sr+2].[O-]C(=O)C([O-])=O KQAGKTURZUKUCH-UHFFFAOYSA-L 0.000 description 1
239000000758 substrate Substances 0.000 description 1
235000019408 sucralose Nutrition 0.000 description 1
BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
239000000725 suspension Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000006188 syrup Substances 0.000 description 1
LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical class OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 description 1
229920001864 tannin Polymers 0.000 description 1
235000018553 tannin Nutrition 0.000 description 1
239000001648 tannin Substances 0.000 description 1
150000003892 tartrate salts Chemical class 0.000 description 1
RYCLIXPGLDDLTM-UHFFFAOYSA-J tetrapotassium;phosphonato phosphate Chemical compound [K+].[K+].[K+].[K+].[O-]P([O-])(=O)OP([O-])([O-])=O RYCLIXPGLDDLTM-UHFFFAOYSA-J 0.000 description 1
229940124597 therapeutic agent Drugs 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
239000002562 thickening agent Substances 0.000 description 1
239000004408 titanium dioxide Substances 0.000 description 1
235000019505 tobacco product Nutrition 0.000 description 1
239000007852 tooth bleaching agent Substances 0.000 description 1
208000004371 toothache Diseases 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
KVSKGMLNBAPGKH-UHFFFAOYSA-N tribromosalicylanilide Chemical compound OC1=C(Br)C=C(Br)C=C1C(=O)NC1=CC=C(Br)C=C1 KVSKGMLNBAPGKH-UHFFFAOYSA-N 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
150000003627 tricarboxylic acid derivatives Chemical class 0.000 description 1
150000003628 tricarboxylic acids Chemical class 0.000 description 1
ICUTUKXCWQYESQ-UHFFFAOYSA-N triclocarban Chemical compound C1=CC(Cl)=CC=C1NC(=O)NC1=CC=C(Cl)C(Cl)=C1 ICUTUKXCWQYESQ-UHFFFAOYSA-N 0.000 description 1
AAAQKTZKLRYKHR-UHFFFAOYSA-N triphenylmethane Chemical compound C1=CC=CC=C1C(C=1C=CC=CC=1)C1=CC=CC=C1 AAAQKTZKLRYKHR-UHFFFAOYSA-N 0.000 description 1
XPFJYKARVSSRHE-UHFFFAOYSA-K trisodium;2-hydroxypropane-1,2,3-tricarboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound [Na+].[Na+].[Na+].OC(=O)CC(O)(C(O)=O)CC(O)=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O XPFJYKARVSSRHE-UHFFFAOYSA-K 0.000 description 1
LEAHFJQFYSDGGP-UHFFFAOYSA-K trisodium;dihydrogen phosphate;hydrogen phosphate Chemical compound [Na+].[Na+].[Na+].OP(O)([O-])=O.OP([O-])([O-])=O LEAHFJQFYSDGGP-UHFFFAOYSA-K 0.000 description 1
108010050327 trypticase-soy broth Proteins 0.000 description 1
239000000080 wetting agent Substances 0.000 description 1
239000000230 xanthan gum Substances 0.000 description 1
229920001285 xanthan gum Polymers 0.000 description 1
229940082509 xanthan gum Drugs 0.000 description 1
235000010493 xanthan gum Nutrition 0.000 description 1
239000000811 xylitol Substances 0.000 description 1
235000010447 xylitol Nutrition 0.000 description 1
HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
229960002675 xylitol Drugs 0.000 description 1
229910052725 zinc Inorganic materials 0.000 description 1
239000011701 zinc Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Birds (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Oral & Maxillofacial Surgery (AREA)
Cosmetics (AREA)

SK426-2003A 2000-10-11 2001-10-03 Tooth whitening composition and method employing dicarboxylic acid whitening agent SK4262003A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US23929600P	2000-10-11	2000-10-11
PCT/IB2001/001837 WO2002030378A2 (en)	2000-10-11	2001-10-03	Tooth whitening composition and method employing dicarboxylic acid whitening agent

Publications (1)

Publication Number	Publication Date
SK4262003A3 true SK4262003A3 (en)	2003-11-04

Family

ID=22901533

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK426-2003A SK4262003A3 (en)	2000-10-11	2001-10-03	Tooth whitening composition and method employing dicarboxylic acid whitening agent

Country Status (27)

Country	Link
US (2)	US20020061282A1 (is)
EP (1)	EP1326580A2 (is)
JP (1)	JP2004510801A (is)
AR (1)	AR030865A1 (is)
AU (1)	AU2001292159A1 (is)
BG (1)	BG107631A (is)
BR (1)	BR0114296A (is)
CA (1)	CA2424769A1 (is)
CZ (1)	CZ2003950A3 (is)
EA (1)	EA200300298A1 (is)
EC (1)	ECSP034550A (is)
EE (1)	EE200300147A (is)
GT (1)	GT200100205A (is)
HN (1)	HN2001000225A (is)
HU (1)	HUP0302491A2 (is)
IL (1)	IL154950A0 (is)
IS (1)	IS6741A (is)
MX (1)	MXPA03002460A (is)
NO (1)	NO20031634L (is)
NZ (1)	NZ525212A (is)
PA (1)	PA8530501A1 (is)
PE (1)	PE20020400A1 (is)
PL (1)	PL359780A1 (is)
SK (1)	SK4262003A3 (is)
SV (1)	SV2002000681A (is)
WO (1)	WO2002030378A2 (is)
ZA (1)	ZA200302115B (is)

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JP4703904B2 (ja) *	2000-07-24	2011-06-15	花王株式会社	口腔用組成物
CA2486905A1 (en) *	2002-05-29	2003-12-04	Unilever Plc	Cosmetic compositions containing salts of malonic acid
JP2004018470A (ja) *	2002-06-18	2004-01-22	Takasago Internatl Corp	抗菌香料組成物および口臭抑制香料組成物ならびにそれらを含有する口腔用組成物
DE20212652U1 (de) *	2002-08-17	2003-12-24	Jörgens, Marin, Dr.	Mundpflegemittel zur Entfernung von Raucherplaque, insbesondere Nikotin und Nikotinabbauprodukten, von Zahnoberflächen
CN1878526B (zh) *	2003-12-08	2010-09-08	吉百利控股有限公司	固体口用牙齿增白组合物
US20060198795A1 (en) *	2005-11-07	2006-09-07	Giniger Martin S	Multi-component oral care compositions
US8137658B2 (en)	2005-06-28	2012-03-20	Isp Investments Inc.	Tooth whitening compositions
US20100015068A1 (en) *	2006-07-06	2010-01-21	Massachusetts Institute Of Technology	Methods and Compositions For Altering Biological Surfaces
US8828363B2 (en) *	2007-08-03	2014-09-09	Gary H. EIREW	Pharmaceutical composition for improving oral hygiene and methods thereof
US20090081136A1 (en)	2007-09-24	2009-03-26	Deepak Sharma	Compositions Useful For Tooth Whitening
PH12013501182A1 (en) *	2010-12-07	2013-07-15	Colgate Palmolive Co	Apparatus for conducting oral care experiments and method of forming and using the same
CA2878877C (en) *	2012-08-10	2019-11-12	Colgate-Palmolive Company	Mouthwash comprising peroxy compound, a first acid and a second acid
US8771651B2 (en) *	2012-09-10	2014-07-08	Johnson & Johnson Consumer Companies, Inc.	Mouth rinses and tooth sensitivity treatment compositions
WO2014152829A1 (en) *	2013-03-14	2014-09-25	Hegemon Enterprises Llc	Methods of reducing or eliminating tooth staining by application of stain barrier films
BR112021009910A2 (pt) *	2018-11-29	2021-08-17	The Hershey Company	preparação e eficácia de uma pastilha para clareamento dos dentes que inclui shmp
AU2021266723A1 (en) *	2020-05-05	2022-11-10	The Procter & Gamble Company	Oral care compositions comprising dicarboxylic acid
EP4146149A1 (en) *	2020-05-05	2023-03-15	The Procter & Gamble Company	Oral care compositions comprising dicarboxylic acid
AU2021268189A1 (en) *	2020-05-05	2022-11-03	The Procter & Gamble Company	Oral care compositions comprising dicarboxylic acid
WO2022165467A1 (en) *	2021-02-01	2022-08-04	The Procter & Gamble Company	Oral composition comprising oxalic acid
JP2024504387A (ja) *	2021-02-01	2024-01-31	ザプロクターアンドギャンブルカンパニー	シュウ酸を含む口腔ケア組成物
US12496262B2 (en) *	2021-09-20	2025-12-16	The Procter & Gamble Company	Jammed emulsion toothpaste compositions
US20230133630A1 (en) *	2021-11-04	2023-05-04	The Procter & Gamble Company	Oral Care Compositions Comprising Dicarboxylic Acid
US20240041728A1 (en) *	2021-11-04	2024-02-08	The Procter & Gamble Company	Oral care compositions comprising dicarboxylic acid
AU2024357555A1 (en) *	2023-10-11	2026-03-19	The Procter & Gamble Company	Oral care compositions comprising dicarboxylic acid
WO2025076709A1 (en) *	2023-10-11	2025-04-17	The Procter & Gamble Company	Oral care compositions comprising dicarboxylic acid

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US5100652A (en) *	1984-03-21	1992-03-31	Alcide Corporation	Disinfecting oral hygiene compositions and process for using the same
US4601899A (en) *	1985-03-27	1986-07-22	Beecham Inc.	Hydrous toothpaste containing TiF4 and chelating agent
GB8607333D0 (en) *	1986-03-25	1986-04-30	Beecham Group Plc	Oral hygiene compositions
GB8906913D0 (en) *	1989-03-28	1989-05-10	Beecham Group Plc	Novel compositions
US5174990A (en) *	1990-02-07	1992-12-29	7-L Corporation	Mouthrinse and method of preparation
US5094843A (en) *	1990-09-10	1992-03-10	Beecham Inc.	Antimicrobial toothpaste
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AU3221497A (en) *	1997-05-30	1998-12-30	Procter & Gamble Company, The	Disinfecting compositions and processes for disinfecting surfaces

2001
- 2001-09-05 US US09/946,213 patent/US20020061282A1/en not_active Abandoned
- 2001-10-03 EA EA200300298A patent/EA200300298A1/ru unknown
- 2001-10-03 MX MXPA03002460A patent/MXPA03002460A/es unknown
- 2001-10-03 IL IL15495001A patent/IL154950A0/xx unknown
- 2001-10-03 WO PCT/IB2001/001837 patent/WO2002030378A2/en not_active Ceased
- 2001-10-03 NZ NZ525212A patent/NZ525212A/en unknown
- 2001-10-03 EE EEP200300147A patent/EE200300147A/xx unknown
- 2001-10-03 PL PL35978001A patent/PL359780A1/xx not_active Application Discontinuation
- 2001-10-03 CA CA002424769A patent/CA2424769A1/en not_active Abandoned
- 2001-10-03 CZ CZ2003950A patent/CZ2003950A3/cs unknown
- 2001-10-03 SK SK426-2003A patent/SK4262003A3/sk not_active Application Discontinuation
- 2001-10-03 JP JP2002533823A patent/JP2004510801A/ja active Pending
- 2001-10-03 EP EP01972388A patent/EP1326580A2/en not_active Withdrawn
- 2001-10-03 AU AU2001292159A patent/AU2001292159A1/en not_active Abandoned
- 2001-10-03 HU HU0302491A patent/HUP0302491A2/hu unknown
- 2001-10-03 BR BR0114296-8A patent/BR0114296A/pt not_active IP Right Cessation
- 2001-10-08 HN HN2001000225A patent/HN2001000225A/es unknown
- 2001-10-09 AR ARP010104727A patent/AR030865A1/es unknown
- 2001-10-10 PA PA20018530501A patent/PA8530501A1/es unknown
- 2001-10-10 PE PE2001000999A patent/PE20020400A1/es not_active Application Discontinuation
- 2001-10-10 SV SV2001000681A patent/SV2002000681A/es unknown
- 2001-10-11 GT GT200100205A patent/GT200100205A/es unknown
2003
- 2003-03-10 IS IS6741A patent/IS6741A/is unknown
- 2003-03-13 BG BG107631A patent/BG107631A/bg unknown
- 2003-03-17 ZA ZA200302115A patent/ZA200302115B/en unknown
- 2003-04-09 NO NO20031634A patent/NO20031634L/no not_active Application Discontinuation
- 2003-04-10 EC EC2003004550A patent/ECSP034550A/es unknown
- 2003-06-13 US US10/461,729 patent/US20030211052A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AR030865A1 (es)	2003-09-03
IS6741A (is)	2003-03-10
EP1326580A2 (en)	2003-07-16
HUP0302491A2 (hu)	2003-11-28
JP2004510801A (ja)	2004-04-08
NO20031634D0 (no)	2003-04-09
ECSP034550A (es)	2003-06-25
BG107631A (bg)	2004-09-30
NO20031634L (no)	2003-04-09
CA2424769A1 (en)	2002-04-18
AU2001292159A1 (en)	2002-04-22
BR0114296A (pt)	2003-07-29
PL359780A1 (en)	2004-09-06
WO2002030378A2 (en)	2002-04-18
US20030211052A1 (en)	2003-11-13
US20020061282A1 (en)	2002-05-23
MXPA03002460A (es)	2004-09-10
HN2001000225A (es)	2001-11-07
GT200100205A (es)	2002-06-25
EA200300298A1 (ru)	2003-10-30
SV2002000681A (es)	2002-12-02
EE200300147A (et)	2003-08-15
CZ2003950A3 (cs)	2003-09-17
ZA200302115B (en)	2004-04-20
WO2002030378A3 (en)	2002-07-25
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