SK47098A3 - Urogenital carcinoma tlp complex peptides and antibodies thereof - Google Patents

Urogenital carcinoma tlp complex peptides and antibodies thereof Download PDF

Info

Publication number: SK47098A3
Authority: SK; Slovakia
Prior art keywords: tlp; peptide; seq; amino acid; sequence
Prior art date: 1996-07-10

Application number

SK470-98A

Other languages

English (en)

Slovak (sk)

Inventor

Giulio Tarro

Original Assignee

Ist Farmacoterapico It Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-10

Filing date

1997-07-02

Publication date

1999-02-11

1997-07-02 Application filed by Ist Farmacoterapico It Spa filed Critical Ist Farmacoterapico It Spa

1999-02-11 Publication of SK47098A3 publication Critical patent/SK47098A3/sk

Links

108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 19
201000009030 Carcinoma Diseases 0.000 title claims abstract description 10
102000004196 processed proteins & peptides Human genes 0.000 title claims description 8
239000008194 pharmaceutical composition Substances 0.000 claims abstract description 3
150000001413 amino acids Chemical group 0.000 claims description 8
206010028980 Neoplasm Diseases 0.000 claims description 7
239000003795 chemical substances by application Substances 0.000 claims description 4
238000000034 method Methods 0.000 claims description 4
238000009007 Diagnostic Kit Methods 0.000 claims description 2
OOCFXNOVSLSHAB-IUCAKERBSA-N Gly-Pro-Pro Chemical compound NCC(=O)N1CCC[C@H]1C(=O)N1[C@H](C(O)=O)CCC1 OOCFXNOVSLSHAB-IUCAKERBSA-N 0.000 claims description 2
239000004480 active ingredient Substances 0.000 claims description 2
210000004392 genitalia Anatomy 0.000 claims description 2
108010070643 prolylglutamic acid Proteins 0.000 claims description 2
238000001114 immunoprecipitation Methods 0.000 claims 2
210000002966 serum Anatomy 0.000 claims 2
AKJRHDMTEJXTPV-ACZMJKKPSA-N Glu-Asn-Ala Chemical compound C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O AKJRHDMTEJXTPV-ACZMJKKPSA-N 0.000 claims 1
238000006243 chemical reaction Methods 0.000 claims 1
239000000835 fiber Substances 0.000 claims 1
125000003275 alpha amino acid group Chemical group 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
208000024313 Testicular Neoplasms Diseases 0.000 description 4
206010057644 Testis cancer Diseases 0.000 description 4
102000004169 proteins and genes Human genes 0.000 description 4
108090000623 proteins and genes Proteins 0.000 description 4
201000003120 testicular cancer Diseases 0.000 description 4
239000007983 Tris buffer Substances 0.000 description 3
210000003734 kidney Anatomy 0.000 description 3
239000006228 supernatant Substances 0.000 description 3
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 3
210000001635 urinary tract Anatomy 0.000 description 3
206010001197 Adenocarcinoma of the cervix Diseases 0.000 description 2
208000034246 Adenocarcinoma of the cervix uteri Diseases 0.000 description 2
206010038486 Renal neoplasms Diseases 0.000 description 2
201000006662 cervical adenocarcinoma Diseases 0.000 description 2
238000001962 electrophoresis Methods 0.000 description 2
239000000284 extract Substances 0.000 description 2
230000009826 neoplastic cell growth Effects 0.000 description 2
QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 1
SWLOHUMCUDRTCL-ZLUOBGJFSA-N Asn-Ala-Asn Chemical compound C[C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)O)NC(=O)[C@H](CC(=O)N)N SWLOHUMCUDRTCL-ZLUOBGJFSA-N 0.000 description 1
206010008342 Cervix carcinoma Diseases 0.000 description 1
YQPFCZVKMUVZIN-AUTRQRHGSA-N Glu-Val-Gln Chemical compound [H]N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O YQPFCZVKMUVZIN-AUTRQRHGSA-N 0.000 description 1
102000007474 Multiprotein Complexes Human genes 0.000 description 1
108010085220 Multiprotein Complexes Proteins 0.000 description 1
102000007079 Peptide Fragments Human genes 0.000 description 1
108010033276 Peptide Fragments Proteins 0.000 description 1
208000006105 Uterine Cervical Neoplasms Diseases 0.000 description 1
238000004458 analytical method Methods 0.000 description 1
230000000890 antigenic effect Effects 0.000 description 1
230000027455 binding Effects 0.000 description 1
238000001574 biopsy Methods 0.000 description 1
201000010881 cervical cancer Diseases 0.000 description 1
210000003679 cervix uteri Anatomy 0.000 description 1
239000000356 contaminant Substances 0.000 description 1
238000003745 diagnosis Methods 0.000 description 1
208000020816 lung neoplasm Diseases 0.000 description 1
208000037841 lung tumor Diseases 0.000 description 1
239000000463 material Substances 0.000 description 1
239000012528 membrane Substances 0.000 description 1
230000001338 necrotic effect Effects 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
238000000734 protein sequencing Methods 0.000 description 1
238000000746 purification Methods 0.000 description 1
239000000243 solution Substances 0.000 description 1
210000004881 tumor cell Anatomy 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Toxicology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

SK470-98A 1996-07-10 1997-07-02 Urogenital carcinoma tlp complex peptides and antibodies thereof SK47098A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT96RM000496A IT1284870B1 (it)	1996-07-10	1996-07-10	Peptidi dei complessi tlp da carcinomi dell'apparato urogenitale e anticorpi diretti contro di essi
PCT/IT1997/000158 WO1998001462A2 (en)	1996-07-10	1997-07-02	Urogenital carcinoma tlp complex peptides and antibodies thereof

Publications (1)

Publication Number	Publication Date
SK47098A3 true SK47098A3 (en)	1999-02-11

Family

ID=11404336

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK470-98A SK47098A3 (en)	1996-07-10	1997-07-02	Urogenital carcinoma tlp complex peptides and antibodies thereof

Country Status (16)

Country	Link
US (3)	US6222010B1 (es)
EP (1)	EP0851872B1 (es)
CN (1)	CN1136230C (es)
AT (1)	ATE200678T1 (es)
AU (1)	AU716721B2 (es)
CA (1)	CA2234151C (es)
DE (1)	DE69704606T2 (es)
DK (1)	DK0851872T3 (es)
ES (1)	ES2156393T3 (es)
GR (1)	GR3036057T3 (es)
IT (1)	IT1284870B1 (es)
NO (1)	NO982227D0 (es)
PT (1)	PT851872E (es)
RU (1)	RU2203679C2 (es)
SK (1)	SK47098A3 (es)
WO (1)	WO1998001462A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1284870B1 (it)	1996-07-10	1998-05-22	Ist Farmacoterapico It Spa	Peptidi dei complessi tlp da carcinomi dell'apparato urogenitale e anticorpi diretti contro di essi
DE10001717C1 (de) *	2000-01-18	2001-04-26	Xcellsis Gmbh	Brennstoffzellensystem
ITMI20011380A1 (it) *	2001-06-29	2002-12-29	Unihart Corp	Antigene tlp e sue applicazioni diagnostiche
CN101712946B (zh) *	2009-09-27	2013-02-27	南通大学附属医院	构建生殖结节器官培养尿道体外发育模型的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4270924A (en) *	1979-04-10	1981-06-02	Crooke Stanley T	Diagnostic method for detecting cancer
IT1206250B (it)	1987-02-18	1989-04-14	Ist Farmacoterapico It Spa	Stiche umane e relativi prodotti metodo per l'estrazione di antigeni di membrana aventi proprieta' immunogene a partire da cellule neopla-
RU2009500C1 (ru) *	1987-03-11	1994-03-15	Фармиталиа Карло Эрба С.Р.Л.	Способ получения цитотоксического коньюгата
IT1262954B (it)	1992-07-03	1996-07-23	Ist Farmacoterapico It Spa	Regioni antigeniche dei complessi tpl e anticorpi diretti contro di essi.
IT1284870B1 (it)	1996-07-10	1998-05-22	Ist Farmacoterapico It Spa	Peptidi dei complessi tlp da carcinomi dell'apparato urogenitale e anticorpi diretti contro di essi

1996
- 1996-07-10 IT IT96RM000496A patent/IT1284870B1/it active IP Right Grant
1997
- 1997-07-02 CN CNB971912130A patent/CN1136230C/zh not_active Expired - Fee Related
- 1997-07-02 ES ES97932002T patent/ES2156393T3/es not_active Expired - Lifetime
- 1997-07-02 SK SK470-98A patent/SK47098A3/sk unknown
- 1997-07-02 RU RU98106385/14A patent/RU2203679C2/ru not_active IP Right Cessation
- 1997-07-02 DE DE69704606T patent/DE69704606T2/de not_active Expired - Fee Related
- 1997-07-02 EP EP97932002A patent/EP0851872B1/en not_active Expired - Lifetime
- 1997-07-02 WO PCT/IT1997/000158 patent/WO1998001462A2/en not_active Ceased
- 1997-07-02 AT AT97932002T patent/ATE200678T1/de not_active IP Right Cessation
- 1997-07-02 AU AU35572/97A patent/AU716721B2/en not_active Ceased
- 1997-07-02 DK DK97932002T patent/DK0851872T3/da active
- 1997-07-02 US US09/051,357 patent/US6222010B1/en not_active Expired - Fee Related
- 1997-07-02 PT PT97932002T patent/PT851872E/pt unknown
- 1997-07-02 CA CA002234151A patent/CA2234151C/en not_active Expired - Fee Related
1998
- 1998-05-15 NO NO982227A patent/NO982227D0/no unknown
2000
- 2000-02-15 US US09/504,089 patent/US20030170750A1/en not_active Abandoned
- 2000-09-14 US US09/661,503 patent/US6664378B1/en not_active Expired - Fee Related
2001
- 2001-06-14 GR GR20010400899T patent/GR3036057T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
US20030170750A1 (en)	2003-09-11
AU3557297A (en)	1998-02-02
DE69704606D1 (de)	2001-05-23
CN1205012A (zh)	1999-01-13
US6664378B1 (en)	2003-12-16
WO1998001462A3 (en)	1998-08-06
CN1136230C (zh)	2004-01-28
DK0851872T3 (da)	2001-06-18
ITRM960496A1 (it)	1998-01-10
ITRM960496A0 (es)	1996-07-10
CA2234151A1 (en)	1998-01-15
DE69704606T2 (de)	2001-11-08
EP0851872A3 (en)	1998-10-14
NO982227L (no)	1998-05-15
ES2156393T3 (es)	2001-06-16
NO982227D0 (no)	1998-05-15
US6222010B1 (en)	2001-04-24
PT851872E (pt)	2001-08-30
WO1998001462A2 (en)	1998-01-15
ATE200678T1 (de)	2001-05-15
EP0851872A2 (en)	1998-07-08
RU2203679C2 (ru)	2003-05-10
CA2234151C (en)	2004-02-03
GR3036057T3 (en)	2001-09-28
AU716721B2 (en)	2000-03-02
EP0851872B1 (en)	2001-04-18
IT1284870B1 (it)	1998-05-22

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