SK50599A3 - Process for the preparation of n-[2- -(dimethylamino)ethyl]acridine-4-carboxamide - Google Patents

Process for the preparation of n-[2- -(dimethylamino)ethyl]acridine-4-carboxamide Download PDF

Info

Publication number
SK50599A3
SK50599A3 SK505-99A SK50599A SK50599A3 SK 50599 A3 SK50599 A3 SK 50599A3 SK 50599 A SK50599 A SK 50599A SK 50599 A3 SK50599 A3 SK 50599A3
Authority
SK
Slovakia
Prior art keywords
formula
compound
defined above
alkyl
acridine
Prior art date
Application number
SK505-99A
Other languages
English (en)
Slovak (sk)
Inventor
William Alexander Denny
Swarnalatha Akuratiya Gamage
Julie Ann Spicer
Michael Wright
David Frank Hayman
Original Assignee
Xenova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9621795.5A external-priority patent/GB9621795D0/en
Priority claimed from GBGB9626457.7A external-priority patent/GB9626457D0/en
Application filed by Xenova Ltd filed Critical Xenova Ltd
Publication of SK50599A3 publication Critical patent/SK50599A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Glass Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Wire Bonding (AREA)
SK505-99A 1996-10-18 1997-10-17 Process for the preparation of n-[2- -(dimethylamino)ethyl]acridine-4-carboxamide SK50599A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9621795.5A GB9621795D0 (en) 1996-10-18 1996-10-18 Pharmaceutical compounds
GBGB9626457.7A GB9626457D0 (en) 1996-12-20 1996-12-20 Process
PCT/GB1997/002884 WO1998017649A1 (en) 1996-10-18 1997-10-17 Process for the preparation of n-[2-(dimethylamino)ethyl]acridine-4-carboxamide

Publications (1)

Publication Number Publication Date
SK50599A3 true SK50599A3 (en) 2000-05-16

Family

ID=26310257

Family Applications (1)

Application Number Title Priority Date Filing Date
SK505-99A SK50599A3 (en) 1996-10-18 1997-10-17 Process for the preparation of n-[2- -(dimethylamino)ethyl]acridine-4-carboxamide

Country Status (20)

Country Link
US (1) US6111109A (id)
EP (1) EP0934277B1 (id)
JP (1) JP2001502682A (id)
KR (1) KR20000049239A (id)
AT (1) ATE232202T1 (id)
AU (1) AU741305B2 (id)
BG (1) BG103328A (id)
BR (1) BR9711945A (id)
CA (1) CA2268413A1 (id)
CZ (1) CZ135199A3 (id)
DE (1) DE69718925D1 (id)
GB (1) GB2333293B (id)
ID (1) ID21677A (id)
NO (1) NO313382B1 (id)
NZ (1) NZ334951A (id)
PL (1) PL332728A1 (id)
RU (1) RU2178785C2 (id)
SK (1) SK50599A3 (id)
TW (1) TW430658B (id)
WO (1) WO1998017649A1 (id)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070299093A1 (en) * 2005-01-27 2007-12-27 Alma Mater Studiorum-Universitá Di Bologna Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation
CA2595994A1 (en) * 2005-01-27 2006-08-03 Alma Mater Studiorum - Universita' Di Bologna Organic compounds useful for the treatment of alzheimer's disease, their use and method of preparation
FR2904317A1 (fr) 2006-07-27 2008-02-01 Inst Nat Sante Rech Med Analogues d'halogenobenzamides marques a titre de radiopharmaceutiques
EP2085390A1 (en) 2008-01-31 2009-08-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Labelled analogues of halobenzamides as multimodal radiopharmaceuticals and their precursors
CN105315205B (zh) * 2015-01-19 2018-03-23 威海惠安康生物科技有限公司 一种以邻硝基苯甲醛和环己醇为原料制备吖啶的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3686180A (en) * 1970-11-04 1972-08-22 Smith Kline French Lab Substituted 9-lower alkylacridine-4-carboxylic acids
NZ201084A (en) * 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
KR100220538B1 (ko) * 1991-01-11 1999-09-15 뮈쉘 쥐르밀 아크리딘 유도체
US5696131A (en) * 1993-01-22 1997-12-09 Xenova Limited Treatment of cancers
CZ104197A3 (en) * 1994-10-05 1997-09-17 Glaxo Wellcome Inc Pharmaceutical preparation

Also Published As

Publication number Publication date
KR20000049239A (ko) 2000-07-25
NO991835L (no) 1999-06-16
RU2178785C2 (ru) 2002-01-27
AU4713697A (en) 1998-05-15
GB2333293A (en) 1999-07-21
GB9908188D0 (en) 1999-06-02
EP0934277A1 (en) 1999-08-11
US6111109A (en) 2000-08-29
AU741305B2 (en) 2001-11-29
DE69718925D1 (de) 2003-03-13
TW430658B (en) 2001-04-21
HK1018456A1 (en) 1999-12-24
GB2333293B (en) 2000-07-12
NO991835D0 (no) 1999-04-16
CA2268413A1 (en) 1998-04-30
JP2001502682A (ja) 2001-02-27
ATE232202T1 (de) 2003-02-15
NZ334951A (en) 2000-12-22
ID21677A (id) 1999-07-08
WO1998017649A1 (en) 1998-04-30
PL332728A1 (en) 1999-10-11
BR9711945A (pt) 1999-08-24
EP0934277B1 (en) 2003-02-05
BG103328A (en) 2000-07-31
CZ135199A3 (cs) 1999-09-15
NO313382B1 (no) 2002-09-23

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