SK6812002A3 - Method for producing a moulded body containing starch, homogenised material containing starch and device for producing a soft capsule - Google Patents

Method for producing a moulded body containing starch, homogenised material containing starch and device for producing a soft capsule Download PDF

Info

Publication number: SK6812002A3
Authority: SK; Slovakia
Prior art keywords: starch; capsule; weight; mass; film
Prior art date: 1999-11-19

Application number

SK681-2002A

Other languages

English (en)

Slovak (sk)

Inventor

Ivan Tomka

Dieter Wolfgang Engel

Erich Brocker

Rico Menard

Original Assignee

Swiss Caps Rechte & Lizenzen

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-19

Filing date

2000-11-16

Publication date

2002-10-08

2000-11-16 Application filed by Swiss Caps Rechte & Lizenzen filed Critical Swiss Caps Rechte & Lizenzen

2002-10-08 Publication of SK6812002A3 publication Critical patent/SK6812002A3/sk

Links

229920002472 Starch Polymers 0.000 title claims abstract description 166
235000019698 starch Nutrition 0.000 title claims abstract description 166
239000008107 starch Substances 0.000 title claims abstract description 160
239000000463 material Substances 0.000 title claims abstract description 46
239000007901 soft capsule Substances 0.000 title claims abstract description 21
238000004519 manufacturing process Methods 0.000 title claims description 49
239000002775 capsule Substances 0.000 claims abstract description 97
238000000034 method Methods 0.000 claims abstract description 66
239000000203 mixture Substances 0.000 claims abstract description 48
230000008569 process Effects 0.000 claims abstract description 47
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 31
239000004014 plasticizer Substances 0.000 claims abstract description 29
238000011049 filling Methods 0.000 claims abstract description 23
229920001169 thermoplastic Polymers 0.000 claims abstract description 17
239000004416 thermosoftening plastic Substances 0.000 claims abstract description 17
229920000945 Amylopectin Polymers 0.000 claims abstract description 12
239000008187 granular material Substances 0.000 claims abstract description 8
238000001816 cooling Methods 0.000 claims abstract description 7
238000002844 melting Methods 0.000 claims abstract description 6
238000001035 drying Methods 0.000 claims abstract description 5
230000008018 melting Effects 0.000 claims abstract 5
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 46
235000011187 glycerol Nutrition 0.000 claims description 23
238000000465 moulding Methods 0.000 claims description 23
VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims description 17
235000014113 dietary fatty acids Nutrition 0.000 claims description 17
239000000194 fatty acid Substances 0.000 claims description 17
229930195729 fatty acid Natural products 0.000 claims description 17
150000004665 fatty acids Chemical class 0.000 claims description 17
238000005538 encapsulation Methods 0.000 claims description 13
239000000835 fiber Substances 0.000 claims description 13
238000012545 processing Methods 0.000 claims description 13
238000002156 mixing Methods 0.000 claims description 12
150000002148 esters Chemical class 0.000 claims description 10
235000010445 lecithin Nutrition 0.000 claims description 9
239000000787 lecithin Substances 0.000 claims description 9
239000000654 additive Substances 0.000 claims description 8
239000000126 substance Substances 0.000 claims description 8
VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 6
239000003795 chemical substances by application Substances 0.000 claims description 5
229920001222 biopolymer Polymers 0.000 claims description 4
-1 polyethylene Polymers 0.000 claims description 4
150000003626 triacylglycerols Chemical class 0.000 claims description 4
239000004698 Polyethylene Substances 0.000 claims description 3
230000000996 additive effect Effects 0.000 claims description 3
OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 claims description 3
229910000019 calcium carbonate Inorganic materials 0.000 claims description 3
239000007884 disintegrant Substances 0.000 claims description 3
238000010438 heat treatment Methods 0.000 claims description 3
229920000573 polyethylene Polymers 0.000 claims description 3
150000005846 sugar alcohols Polymers 0.000 claims description 3
102000013142 Amylases Human genes 0.000 claims description 2
108010065511 Amylases Proteins 0.000 claims description 2
BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical class OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 2
229910052783 alkali metal Inorganic materials 0.000 claims description 2
150000001340 alkali metals Chemical class 0.000 claims description 2
150000001408 amides Chemical class 0.000 claims description 2
150000001412 amines Chemical class 0.000 claims description 2
235000019418 amylase Nutrition 0.000 claims description 2
239000003963 antioxidant agent Substances 0.000 claims description 2
150000004649 carbonic acid derivatives Chemical class 0.000 claims description 2
230000002708 enhancing effect Effects 0.000 claims description 2
150000002500 ions Chemical class 0.000 claims description 2
150000007524 organic acids Chemical class 0.000 claims description 2
235000005985 organic acids Nutrition 0.000 claims description 2
229920000223 polyglycerol Polymers 0.000 claims description 2
229920001184 polypeptide Polymers 0.000 claims description 2
102000004196 processed proteins & peptides Human genes 0.000 claims description 2
108090000765 processed proteins & peptides Proteins 0.000 claims description 2
150000003462 sulfoxides Chemical class 0.000 claims description 2
150000004040 pyrrolidinones Chemical class 0.000 claims 2
229940025131 amylases Drugs 0.000 claims 1
230000000181 anti-adherent effect Effects 0.000 claims 1
239000003086 colorant Substances 0.000 claims 1
150000001875 compounds Chemical class 0.000 claims 1
150000001261 hydroxy acids Chemical class 0.000 claims 1
238000005192 partition Methods 0.000 claims 1
239000003755 preservative agent Substances 0.000 claims 1
238000004898 kneading Methods 0.000 abstract description 7
239000000047 product Substances 0.000 abstract description 4
238000007493 shaping process Methods 0.000 abstract description 3
239000013067 intermediate product Substances 0.000 abstract 2
238000002360 preparation method Methods 0.000 abstract 2
239000010408 film Substances 0.000 description 60
239000011257 shell material Substances 0.000 description 23
238000001125 extrusion Methods 0.000 description 18
239000000600 sorbitol Substances 0.000 description 13
235000010356 sorbitol Nutrition 0.000 description 13
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 8
IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 7
230000015556 catabolic process Effects 0.000 description 7
238000006731 degradation reaction Methods 0.000 description 7
238000005265 energy consumption Methods 0.000 description 7
239000010410 layer Substances 0.000 description 7
229940067606 lecithin Drugs 0.000 description 7
239000000155 melt Substances 0.000 description 7
241000196324 Embryophyta Species 0.000 description 6
229920001971 elastomer Polymers 0.000 description 6
239000000945 filler Substances 0.000 description 6
239000000843 powder Substances 0.000 description 6
239000005060 rubber Substances 0.000 description 6
229920000856 Amylose Polymers 0.000 description 5
238000004090 dissolution Methods 0.000 description 5
230000000694 effects Effects 0.000 description 5
239000007788 liquid Substances 0.000 description 5
229920000642 polymer Polymers 0.000 description 5
238000006116 polymerization reaction Methods 0.000 description 5
238000003466 welding Methods 0.000 description 5
239000004480 active ingredient Substances 0.000 description 4
239000007795 chemical reaction product Substances 0.000 description 4
230000001419 dependent effect Effects 0.000 description 4
YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 description 4
SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 description 4
230000007935 neutral effect Effects 0.000 description 4
108010010803 Gelatin Proteins 0.000 description 3
229920008262 Thermoplastic starch Polymers 0.000 description 3
230000015572 biosynthetic process Effects 0.000 description 3
239000012467 final product Substances 0.000 description 3
239000008273 gelatin Substances 0.000 description 3
229920000159 gelatin Polymers 0.000 description 3
235000019322 gelatine Nutrition 0.000 description 3
235000011852 gelatine desserts Nutrition 0.000 description 3
238000002347 injection Methods 0.000 description 3
239000007924 injection Substances 0.000 description 3
230000002427 irreversible effect Effects 0.000 description 3
239000004628 starch-based polymer Substances 0.000 description 3
238000003860 storage Methods 0.000 description 3
230000008961 swelling Effects 0.000 description 3
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
125000004432 carbon atom Chemical group C* 0.000 description 2
235000010418 carrageenan Nutrition 0.000 description 2
239000000679 carrageenan Substances 0.000 description 2
229920001525 carrageenan Polymers 0.000 description 2
229940113118 carrageenan Drugs 0.000 description 2
239000001913 cellulose Substances 0.000 description 2
229920002678 cellulose Polymers 0.000 description 2
230000008859 change Effects 0.000 description 2
238000010382 chemical cross-linking Methods 0.000 description 2
238000006243 chemical reaction Methods 0.000 description 2
239000011248 coating agent Substances 0.000 description 2
238000000576 coating method Methods 0.000 description 2
229920006037 cross link polymer Polymers 0.000 description 2
230000006378 damage Effects 0.000 description 2
239000012530 fluid Substances 0.000 description 2
238000000265 homogenisation Methods 0.000 description 2
238000012432 intermediate storage Methods 0.000 description 2
239000000845 maltitol Substances 0.000 description 2
235000010449 maltitol Nutrition 0.000 description 2
229920001542 oligosaccharide Polymers 0.000 description 2
150000002482 oligosaccharides Chemical class 0.000 description 2
238000004806 packaging method and process Methods 0.000 description 2
229920001592 potato starch Polymers 0.000 description 2
239000002356 single layer Substances 0.000 description 2
239000000243 solution Substances 0.000 description 2
238000006467 substitution reaction Methods 0.000 description 2
238000012360 testing method Methods 0.000 description 2
230000009466 transformation Effects 0.000 description 2
UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 2
OMDQUFIYNPYJFM-XKDAHURESA-N (2r,3r,4s,5r,6s)-2-(hydroxymethyl)-6-[[(2r,3s,4r,5s,6r)-4,5,6-trihydroxy-3-[(2s,3s,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@H](O)[C@H](O)O1 OMDQUFIYNPYJFM-XKDAHURESA-N 0.000 description 1
FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 1
239000004382 Amylase Substances 0.000 description 1
229920001685 Amylomaize Polymers 0.000 description 1
241001474374 Blennius Species 0.000 description 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
229910052684 Cerium Inorganic materials 0.000 description 1
229920000926 Galactomannan Polymers 0.000 description 1
229920001503 Glucan Polymers 0.000 description 1
229920002581 Glucomannan Polymers 0.000 description 1
229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
229920000057 Mannan Polymers 0.000 description 1
241001465754 Metazoa Species 0.000 description 1
229920000881 Modified starch Polymers 0.000 description 1
239000002202 Polyethylene glycol Substances 0.000 description 1
DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 1
150000001241 acetals Chemical class 0.000 description 1
239000002253 acid Substances 0.000 description 1
239000013543 active substance Substances 0.000 description 1
238000004026 adhesive bonding Methods 0.000 description 1
238000004220 aggregation Methods 0.000 description 1
230000002776 aggregation Effects 0.000 description 1
229940072056 alginate Drugs 0.000 description 1
235000010443 alginic acid Nutrition 0.000 description 1
229920000615 alginic acid Polymers 0.000 description 1
239000002585 base Substances 0.000 description 1
238000009835 boiling Methods 0.000 description 1
239000005018 casein Substances 0.000 description 1
BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
235000021240 caseins Nutrition 0.000 description 1
GWXLDORMOJMVQZ-UHFFFAOYSA-N cerium Chemical compound [Ce] GWXLDORMOJMVQZ-UHFFFAOYSA-N 0.000 description 1
238000003776 cleavage reaction Methods 0.000 description 1
238000002288 cocrystallisation Methods 0.000 description 1
238000010276 construction Methods 0.000 description 1
230000007423 decrease Effects 0.000 description 1
230000003111 delayed effect Effects 0.000 description 1
239000000975 dye Substances 0.000 description 1
230000008030 elimination Effects 0.000 description 1
238000003379 elimination reaction Methods 0.000 description 1
239000003623 enhancer Substances 0.000 description 1
230000007717 exclusion Effects 0.000 description 1
230000029142 excretion Effects 0.000 description 1
239000003925 fat Substances 0.000 description 1
235000019197 fats Nutrition 0.000 description 1
239000002657 fibrous material Substances 0.000 description 1
239000011888 foil Substances 0.000 description 1
235000013305 food Nutrition 0.000 description 1
239000012634 fragment Substances 0.000 description 1
210000001035 gastrointestinal tract Anatomy 0.000 description 1
239000000499 gel Substances 0.000 description 1
239000007903 gelatin capsule Substances 0.000 description 1
239000011521 glass Substances 0.000 description 1
150000004676 glycans Chemical class 0.000 description 1
239000007902 hard capsule Substances 0.000 description 1
230000036571 hydration Effects 0.000 description 1
238000006703 hydration reaction Methods 0.000 description 1
229910052739 hydrogen Inorganic materials 0.000 description 1
239000001257 hydrogen Substances 0.000 description 1
125000002887 hydroxy group Chemical class [H]O* 0.000 description 1
239000001341 hydroxy propyl starch Substances 0.000 description 1
239000001863 hydroxypropyl cellulose Substances 0.000 description 1
235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
235000013828 hydroxypropyl starch Nutrition 0.000 description 1
229940071676 hydroxypropylcellulose Drugs 0.000 description 1
238000010348 incorporation Methods 0.000 description 1
238000001746 injection moulding Methods 0.000 description 1
230000003993 interaction Effects 0.000 description 1
239000004922 lacquer Substances 0.000 description 1
238000003475 lamination Methods 0.000 description 1
230000007774 longterm Effects 0.000 description 1
239000000314 lubricant Substances 0.000 description 1
229920002521 macromolecule Polymers 0.000 description 1
VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 description 1
229940035436 maltitol Drugs 0.000 description 1
238000005259 measurement Methods 0.000 description 1
238000000691 measurement method Methods 0.000 description 1
235000019426 modified starch Nutrition 0.000 description 1
150000002763 monocarboxylic acids Chemical class 0.000 description 1
239000002159 nanocrystal Substances 0.000 description 1
229920005615 natural polymer Polymers 0.000 description 1
210000003739 neck Anatomy 0.000 description 1
239000005022 packaging material Substances 0.000 description 1
230000000704 physical effect Effects 0.000 description 1
239000002985 plastic film Substances 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
229920002959 polymer blend Polymers 0.000 description 1
229920001282 polysaccharide Polymers 0.000 description 1
239000005017 polysaccharide Substances 0.000 description 1
229940088417 precipitated calcium carbonate Drugs 0.000 description 1
238000003825 pressing Methods 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
238000004080 punching Methods 0.000 description 1
239000002994 raw material Substances 0.000 description 1
230000002441 reversible effect Effects 0.000 description 1
150000004671 saturated fatty acids Chemical class 0.000 description 1
235000003441 saturated fatty acids Nutrition 0.000 description 1
230000007017 scission Effects 0.000 description 1
239000011265 semifinished product Substances 0.000 description 1
238000000926 separation method Methods 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000002904 solvent Substances 0.000 description 1
239000007858 starting material Substances 0.000 description 1
229920001059 synthetic polymer Polymers 0.000 description 1
239000010409 thin film Substances 0.000 description 1
239000004408 titanium dioxide Substances 0.000 description 1
230000007704 transition Effects 0.000 description 1
235000019871 vegetable fat Nutrition 0.000 description 1
238000009423 ventilation Methods 0.000 description 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
229920002554 vinyl polymer Polymers 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
- Y10T428/1334—Nonself-supporting tubular film or bag [e.g., pouch, envelope, packet, etc.]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Compositions Of Macromolecular Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Seasonings (AREA)
Noodles (AREA)
Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
Processes Of Treating Macromolecular Substances (AREA)
Cosmetics (AREA)
Biological Depolymerization Polymers (AREA)

SK681-2002A 1999-11-19 2000-11-16 Method for producing a moulded body containing starch, homogenised material containing starch and device for producing a soft capsule SK6812002A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP99811071A EP1103254B1 (de)	1999-11-19	1999-11-19	Verfahren zum Herstellen eines Stärke enthaltenden Formkörpers, homogenisierte Stärke enthaltende Masse und Vorrichtung zum Herstellen einer Weichkapsel
PCT/CH2000/000616 WO2001037817A1 (de)	1999-11-19	2000-11-16	Verfahren zum herstellen eines stärke enthaltenden formkörpers

Publications (1)

Publication Number	Publication Date
SK6812002A3 true SK6812002A3 (en)	2002-10-08

Family

ID=8243152

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK681-2002A SK6812002A3 (en)	1999-11-19	2000-11-16	Method for producing a moulded body containing starch, homogenised material containing starch and device for producing a soft capsule

Country Status (23)

Country	Link
US (1)	US6790495B1 (2)
EP (2)	EP1103254B1 (2)
JP (2)	JP2004510456A (2)
KR (1)	KR100795381B1 (2)
CN (1)	CN100379409C (2)
AT (1)	ATE291420T1 (2)
AU (1)	AU783089B2 (2)
BR (1)	BR0015669A (2)
CA (1)	CA2391963C (2)
CO (1)	CO5261553A1 (2)
CZ (1)	CZ20021700A3 (2)
DE (1)	DE59911807D1 (2)
ES (1)	ES2242371T3 (2)
HU (1)	HUP0203299A2 (2)
IL (1)	IL149425A0 (2)
MX (1)	MXPA02004980A (2)
NO (1)	NO20022331L (2)
PL (1)	PL204120B1 (2)
PT (1)	PT1103254E (2)
RU (1)	RU2002116368A (2)
SK (1)	SK6812002A3 (2)
WO (1)	WO2001037817A1 (2)
ZA (1)	ZA200203938B (2)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT1103254E (pt) *	1999-11-19	2005-07-29	Swiss Caps Rechte & Lizenzen	Processo para a preparacao de um corpo moldado que contem amido, de uma massa homogeneizada que contem amido e dispositivo para a preparacao de uma capsula macia
GB2398499B (en) *	2000-02-16	2004-11-24	Bioprogress Technology Ltd	Two layer capsules
US6375981B1 (en) *	2000-06-01	2002-04-23	A. E. Staley Manufacturing Co.	Modified starch as a replacement for gelatin in soft gel films and capsules
US6528088B1 (en)	2000-06-01	2003-03-04	A. E. Staley Manufacturing Co.	Highly flexible starch-based films
EP1292639B1 (en) *	2000-06-01	2009-03-11	A.E. Staley Manufacturing Company	Highly flexible starch-based films
ATE349204T1 (de) *	2000-11-09	2007-01-15	Celanese Ventures Gmbh	Weichkapseln umfassend ein stärkegemisch verringerten verzweigungsgrades
ES2334973T3 (es)	2000-12-29	2010-03-18	Swiss Caps Rechte Und Lizenzen Ag	Procedimiento y dispositivo para la obtencion de cuerpos moldeados a partir de un material biopolimero.
EP1258242A1 (de) *	2001-05-15	2002-11-20	Swiss Caps Rechte und Lizenzen AG	Verfahren zum Herstellen von Formkörpern, insbesondere von Weichkapseln
EP1262174A1 (en) *	2001-06-01	2002-12-04	Celanese Ventures GmbH	Two part hard shell capsule made of poly(1,4-alpha-D-glucane) and starch
US20050163833A1 (en) *	2001-10-23	2005-07-28	Rolf Muller	Production of starch-gel-based shaped bodies
US6949256B2 (en) *	2002-01-18	2005-09-27	Banner Pharmacaps, Inc.	Non-gelatin capsule shell formulation
US7887838B2 (en) *	2002-01-18	2011-02-15	Banner Pharmacaps, Inc.	Non-gelatin film and method and apparatus for producing same
WO2003090726A2 (en) *	2002-04-25	2003-11-06	Banner Pharmacaps, Inc.	Chewable soft capsule
US20050008677A1 (en) *	2003-04-14	2005-01-13	Fmc Corporation	Delivery system of homogeneous, thermoreversible gel film containing kappa-2 carrageenan
US20050019294A1 (en) *	2003-04-14	2005-01-27	Fmc Corporation	Homogeneous, thermoreversible alginate films and soft capsules made therefrom
US20050048185A1 (en) *	2003-04-14	2005-03-03	Fmc Corporation	Delivery systems of homogeneous, thermoreversible low viscosity polymannan gum films
US7816341B2 (en) *	2003-04-14	2010-10-19	Fmc Corporation	Homogeneous, thermoreversible gel containing reduced viscosity carrageenan and products made therefrom
US20050019295A1 (en) *	2003-04-14	2005-01-27	Fmc Corporation	Homogeneous, thermoreversible low viscosity polymannan gum films and soft capsules made therefrom
US20050013847A1 (en) *	2003-04-14	2005-01-20	Fmc Corporation	Delivery systems of homogeneous, thermoreversible alginate films
JP2007525451A (ja) *	2003-04-14	2007-09-06	エフ　エム　シー　コーポレーション	均一かつ熱可逆性アルギネートフィルムの伝達システム
US8802139B2 (en)	2003-06-26	2014-08-12	Intellipharmaceutics Corp.	Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
EP1528069A1 (de) *	2003-10-29	2005-05-04	SWISS CAPS Rechte und Lizenzen AG	Verbesserte Materialien aus Stärke
JP2005170863A (ja) *	2003-12-12	2005-06-30	Nippon Starch Chemical Co Ltd	デンプン組成物を用いた軟カプセル剤、その製造方法およびその製造用自動機
US7494667B2 (en)	2004-03-02	2009-02-24	Brunob Ii B.V.	Blends of different acyl gellan gums and starch
EP1580229A1 (en) *	2004-03-22	2005-09-28	Warner-Lambert Company Llc	Biopolymer compositons and products thereof
ES2356818T3 (es)	2004-04-16	2011-04-13	Swiss Caps Rechte Und Lizenzen Ag	Procedimiento para la obtención de cuerpos moldeados a partir de plastómeros.
US10624858B2 (en)	2004-08-23	2020-04-21	Intellipharmaceutics Corp	Controlled release composition using transition coating, and method of preparing same
US10064828B1 (en)	2005-12-23	2018-09-04	Intellipharmaceutics Corp.	Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US10960077B2 (en)	2006-05-12	2021-03-30	Intellipharmaceutics Corp.	Abuse and alcohol resistant drug composition
US8574624B2 (en) *	2006-11-17	2013-11-05	Corn Products Development, Inc.	Highly inhibited starch fillers for films and capsules
US8383134B2 (en)	2007-03-01	2013-02-26	Bioneedle Technologies Group B.V.	Biodegradable material based on opened starch
EP2108677A1 (de) *	2008-04-10	2009-10-14	Swiss Caps Rechte und Lizenzen AG	Thermoplastische Stärkemassen
JP5203793B2 (ja) *	2008-04-28	2013-06-05	株式会社東芝	画像診断支援装置
CH700543A2 (de)	2009-03-03	2010-09-15	Innogel Ag	Film auf Basis von Stärke.
EP2410970B1 (de)	2009-03-26	2013-02-13	Swiss Caps Rechte und Lizenzen AG	Verfahren und vorrichtung zur herstellung von weichkapseln
US20120049410A1 (en)	2010-07-19	2012-03-01	Carlos Salazar Altamar	Apparatus and process for making soft gel capsules
ES2617654T3 (es)	2011-04-20	2017-06-19	Suheung Co., Ltd.	Composición de la cubierta de cápsula blanda de origen no animal que tiene dureza de la cubierta y desintegración, mejoradas
KR101294614B1 (ko) *	2012-03-16	2013-08-08	주식회사 서흥캅셀	타피오카 변성전분을 주기재로 사용한 연질 캡슐 피막 조성물
CN103495176B (zh) *	2013-10-26	2015-01-28	中山市凯博思淀粉材料科技有限公司	一种共混挤出法制备淀粉基软胶囊的方法
CN103520133B (zh) *	2013-10-26	2015-02-04	中山市凯博思淀粉材料科技有限公司	一种淀粉基软胶囊的制备方法
CN103550065B (zh) *	2013-10-26	2015-01-28	中山市凯博思淀粉材料科技有限公司	一种复合挤出法生产淀粉基软胶囊的方法
CN103834066B (zh) *	2014-03-05	2015-07-22	中国科学院青岛生物能源与过程研究所	一种用于制备淀粉胶囊的低粘淀粉胶及其制备方法和应用
CN103893772B (zh)	2014-04-21	2015-08-26	湖南尔康制药股份有限公司	一种羟丙基淀粉空心胶囊及其制备工艺
US10016369B2 (en)	2014-06-04	2018-07-10	Capsugel Belgium Nv	Stable dosage form articles for oral administration
CA2910865C (en)	2014-07-15	2016-11-29	Isa Odidi	Compositions and methods for reducing overdose
DE102014019214A1 (de)	2014-12-23	2016-06-23	Bio-Tec Biologische Naturverpackungen Gmbh & Co.Kg	Verfahren zur Herstellung von Formteilen
BR112017022523B1 (pt)	2015-04-23	2023-12-19	Basf Se	Formulação para cápsulas de gel, cápsula de gel, e, processo para produção de uma formulação
PL239878B1 (pl)	2016-03-30	2022-01-24	Gdanski Univ Medyczny	Wodna kompozycja oraz sposób wytwarzania dojelitowych elastycznych filmów do sporządzania kapsułek z wodnej kompozycji oraz dojelitowy elastyczny film do sporządzania kapsułek miękkich
US11517535B2 (en)	2018-05-14	2022-12-06	Capsugel Belgium Nv	Capsules with opacifier
US12589076B2 (en)	2019-10-10	2026-03-31	Capsugel Belgium Nv	Gelatin capsules with ground calcium carbonate

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4673438A (en) *	1984-02-13	1987-06-16	Warner-Lambert Company	Polymer composition for injection molding
CH669201A5 (de) *	1986-05-05	1989-02-28	Warner Lambert Co	Bei raumtemperaturen feste und freifliessende basiszusammensetzung fuer das druckformen.
GB2208651B (en) *	1987-08-18	1991-05-08	Warner Lambert Co	Shaped articles made from pre-processed starch
IE66735B1 (en) *	1988-11-03	1996-02-07	Biotec Biolog Naturverpack	Thermoplastically workable starch and a method for the manufacture thereof
US5362777A (en) *	1988-11-03	1994-11-08	Ivan Tomka	Thermoplastically processable starch and a method of making it
IT1234783B (it) *	1989-05-30	1992-05-27	Butterfly Srl	Procedimento per la produzione di composizioni a base di amido destrutturato e composizioni cosi ottenute
ATE126477T1 (de) *	1989-06-01	1995-09-15	Starch Australasia Limited	Geformte gegenstände aus stärke deriviert.
JP2785981B2 (ja) *	1989-11-20	1998-08-13	株式会社資生堂	乳化組成物
ES2103003T3 (es) *	1990-08-30	1997-08-16	Warner Lambert Co	Articulos formados de una fusion de almidon termoplastica.
EP0559827B1 (en) *	1990-11-28	1997-08-27	R.P. Scherer Corporation	High amylose starch substituted gelatin capsules
IT1256693B (it) *	1992-03-10	1995-12-12	Novamont Spa	Composizione polimerica amidacea filmabile, ed articoli sagomati, particolarmente film e foglie ottenibili da tale composizione, aventi elevato effetto barriera e procedimento relativo.
GB9606371D0 (en) *	1996-03-26	1996-06-05	Brown Malcolm D	An encapsulation process
PT1103254E (pt) *	1999-11-19	2005-07-29	Swiss Caps Rechte & Lizenzen	Processo para a preparacao de um corpo moldado que contem amido, de uma massa homogeneizada que contem amido e dispositivo para a preparacao de uma capsula macia

1999
- 1999-11-19 PT PT99811071T patent/PT1103254E/pt unknown
- 1999-11-19 AT AT99811071T patent/ATE291420T1/de not_active IP Right Cessation
- 1999-11-19 DE DE59911807T patent/DE59911807D1/de not_active Expired - Lifetime
- 1999-11-19 EP EP99811071A patent/EP1103254B1/de not_active Expired - Lifetime
- 1999-11-19 ES ES99811071T patent/ES2242371T3/es not_active Expired - Lifetime
2000
- 2000-06-29 US US09/606,219 patent/US6790495B1/en not_active Expired - Fee Related
- 2000-11-16 BR BR0015669-8A patent/BR0015669A/pt not_active Application Discontinuation
- 2000-11-16 HU HU0203299A patent/HUP0203299A2/hu unknown
- 2000-11-16 CZ CZ20021700A patent/CZ20021700A3/cs unknown
- 2000-11-16 RU RU2002116368/15A patent/RU2002116368A/ru unknown
- 2000-11-16 PL PL356177A patent/PL204120B1/pl unknown
- 2000-11-16 CA CA002391963A patent/CA2391963C/en not_active Expired - Lifetime
- 2000-11-16 SK SK681-2002A patent/SK6812002A3/sk unknown
- 2000-11-16 WO PCT/CH2000/000616 patent/WO2001037817A1/de not_active Ceased
- 2000-11-16 KR KR1020027006325A patent/KR100795381B1/ko not_active Expired - Fee Related
- 2000-11-16 EP EP00974227A patent/EP1229904A1/de not_active Withdrawn
- 2000-11-16 IL IL14942500A patent/IL149425A0/xx not_active IP Right Cessation
- 2000-11-16 CN CNB00818447XA patent/CN100379409C/zh not_active Expired - Fee Related
- 2000-11-16 AU AU12628/01A patent/AU783089B2/en not_active Expired
- 2000-11-16 JP JP2001539432A patent/JP2004510456A/ja active Pending
- 2000-11-16 MX MXPA02004980A patent/MXPA02004980A/es unknown
- 2000-11-20 CO CO00088085A patent/CO5261553A1/es not_active Application Discontinuation
2002
- 2002-05-15 NO NO20022331A patent/NO20022331L/no unknown
- 2002-05-17 ZA ZA200203938A patent/ZA200203938B/xx unknown
2006
- 2006-12-07 JP JP2006330133A patent/JP2007167637A/ja active Pending

Also Published As

Publication number	Publication date
ZA200203938B (en)	2005-01-18
DE59911807D1 (de)	2005-04-28
CA2391963A1 (en)	2001-05-31
KR20020082460A (ko)	2002-10-31
NO20022331L (no)	2002-07-11
US6790495B1 (en)	2004-09-14
CN100379409C (zh)	2008-04-09
AU783089B2 (en)	2005-09-22
IL149425A0 (en)	2002-11-10
HK1055690A1 (zh)	2004-01-21
JP2004510456A (ja)	2004-04-08
MXPA02004980A (es)	2003-10-14
PT1103254E (pt)	2005-07-29
PL204120B1 (pl)	2009-12-31
PL356177A1 (en)	2004-06-14
HUP0203299A2 (en)	2003-03-28
CN1423554A (zh)	2003-06-11
EP1229904A1 (de)	2002-08-14
EP1103254B1 (de)	2005-03-23
KR100795381B1 (ko)	2008-01-17
NO20022331D0 (no)	2002-05-15
WO2001037817A1 (de)	2001-05-31
ES2242371T3 (es)	2005-11-01
ATE291420T1 (de)	2005-04-15
BR0015669A (pt)	2002-07-23
JP2007167637A (ja)	2007-07-05
RU2002116368A (ru)	2004-01-20
CA2391963C (en)	2007-10-30
CZ20021700A3 (cs)	2003-06-18
CO5261553A1 (es)	2003-03-31
AU1262801A (en)	2001-06-04
EP1103254A1 (de)	2001-05-30

Publication	Publication Date	Title
SK6812002A3 (en)	2002-10-08	Method for producing a moulded body containing starch, homogenised material containing starch and device for producing a soft capsule
US7195777B2 (en)	2007-03-27	Method and apparatus for blowmoding capsules of polyvinylalcohol and blowmolded polyvinylalcohol capsules
JP2007167637A5 (2)	2007-11-08
JPS6054322B2 (ja)	1985-11-29	成形物の製法
AU2001235855A1 (en)	2001-11-22	Method and apparatus for blowmoding capsules of polyvinylalcohol and blowmolded polyvinylalcohol capsules
PL206265B1 (pl)	2010-07-30	Biodegradowalna kompozycja polimerowa, jej zastosowanie, sposób otrzymywania produktów z biodegradowalnej kompozycji polimerowej oraz kompozycja polimerowa służąca do wytwarzania folii biodegradowalnej
US6313105B1 (en)	2001-11-06	Thermoplastic mixtures containing dialdehyde starch and natural polymers
CN102311647B (zh)	2015-06-17	一种植物蛋白魔芋胶复合可降解可食用膜的生产技术
EP1437129B1 (de)	2007-10-24	Formkörper bestehend aus gelatinfreiem Material und gefüllt mit einer flüssigen Füllmasse
JP6951064B2 (ja)	2021-10-20	脂肪族ポリエステル樹脂組成物を用いた包装材料
CN103315976B (zh)	2015-09-16	一种淀粉硬胶囊壳的制备方法
US20040087467A1 (en)	2004-05-06	Edible dissolving gelatin strips
EP1258242A1 (de)	2002-11-20	Verfahren zum Herstellen von Formkörpern, insbesondere von Weichkapseln
JP4057927B2 (ja)	2008-03-05	デンプン加水分解糖類およびその縮重合物
HK1055690B (en)	2009-02-06	Method for producing a moulded body containing starch
CN105860492A (zh)	2016-08-17	一种可食性包装膜材料的制备方法
WO2005047341A1 (de)	2005-05-26	Verbesserte materialien aus polysacchariden
WO2024024847A1 (ja)	2024-02-01	水溶性フィルムの製造方法、水溶性フィルム、包装体及び薬剤包装体
WO2024024848A1 (ja)	2024-02-01	水溶性フィルムの製造方法、水溶性フィルム、包装体及び薬剤包装体
KR20030062823A (ko)	2003-07-28	식용성 필름의 제조방법