SMT201700460T1 - Agenti antifungini e loro usi - Google Patents

Agenti antifungini e loro usi

Info

Publication number
SMT201700460T1
SMT201700460T1 SM20170460T SMT201700460T SMT201700460T1 SM T201700460 T1 SMT201700460 T1 SM T201700460T1 SM 20170460 T SM20170460 T SM 20170460T SM T201700460 T SMT201700460 T SM T201700460T SM T201700460 T1 SMT201700460 T1 SM T201700460T1
Authority
SM
San Marino
Prior art keywords
antifungal agents
antifungal
agents
Prior art date
Application number
SM20170460T
Other languages
English (en)
Inventor
Kenneth Duke James Jr
Christopher Patrick Laudeman
Navdeep Balkrishna Malkar
Balasingham Radhakrishnan
Original Assignee
Cidara Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cidara Therapeutics Inc filed Critical Cidara Therapeutics Inc
Publication of SMT201700460T1 publication Critical patent/SMT201700460T1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SM20170460T 2011-03-03 2012-03-02 Agenti antifungini e loro usi SMT201700460T1 (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161448807P 2011-03-03 2011-03-03
PCT/US2012/027451 WO2012119065A2 (en) 2011-03-03 2012-03-02 Antifungal agents and uses thereof
EP12751994.0A EP2680873B1 (en) 2011-03-03 2012-03-02 Antifungal agents and uses thereof

Publications (1)

Publication Number Publication Date
SMT201700460T1 true SMT201700460T1 (it) 2018-01-11

Family

ID=46758514

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20170460T SMT201700460T1 (it) 2011-03-03 2012-03-02 Agenti antifungini e loro usi

Country Status (21)

Country Link
US (6) US8722619B2 (it)
EP (2) EP3192803B1 (it)
JP (4) JP5809296B2 (it)
CN (2) CN106279369B (it)
CA (2) CA2865791C (it)
CY (2) CY1119709T1 (it)
DK (1) DK2680873T3 (it)
ES (1) ES2645074T3 (it)
FI (1) FIC20240022I1 (it)
FR (1) FR24C1027I2 (it)
HR (1) HRP20171579T8 (it)
HU (2) HUE036778T2 (it)
LT (2) LT2680873T (it)
NL (1) NL301280I2 (it)
NO (1) NO2680873T3 (it)
PL (1) PL2680873T3 (it)
PT (1) PT2680873T (it)
RS (1) RS56426B1 (it)
SI (1) SI2680873T1 (it)
SM (1) SMT201700460T1 (it)
WO (1) WO2012119065A2 (it)

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ES2645074T3 (es) 2011-03-03 2017-12-04 Cidara Therapeutics, Inc. Agentes antifúngicos y sus usos
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US20160213742A1 (en) * 2013-09-04 2016-07-28 Cidara Therapeutics, Inc. Compositions and methods for the treatment of fungal infections
WO2015167989A1 (en) * 2014-04-28 2015-11-05 University Of Central Florida Research Foundation, Inc. Compositions, methods of making a composition, and methods of use
WO2016201283A1 (en) * 2015-06-12 2016-12-15 Cidara Therapeutics, Inc. Antifungal agents
WO2017049102A1 (en) * 2015-09-16 2017-03-23 Cidara Therapeutics, Inc. Methods for treating fungal infections
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WO2017161016A1 (en) * 2016-03-16 2017-09-21 Cidara Therapeutics, Inc. Dosing regimens for treatment of fungal infections
CN109789193A (zh) 2016-09-13 2019-05-21 普罗瑟拉生物公司 使用间α抑制蛋白治疗肺病的方法
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EP3615937B1 (en) 2017-04-25 2026-01-28 Prothera Biologics, Inc. Methods for quantifying inter-alpha inhibitor proteins
US11197909B2 (en) 2017-07-12 2021-12-14 Cidara Therapeutics, Inc. Compositions and methods for the treatment of fungal infections
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WO2020086931A1 (en) * 2018-10-25 2020-04-30 Cidara Therapeutics, Inc. Polymorph of echinocandin antifungal agent
US12466856B2 (en) 2019-12-06 2025-11-11 Shanghai Senhui Medicine Co., Ltd. Echinocandin analogues and preparation method therefor
US20240262866A1 (en) 2021-06-03 2024-08-08 Shanghai Senhui Medicine Co., Ltd. Method for preparing anidulafungin derivative
CN115850383A (zh) * 2022-12-15 2023-03-28 江苏九阳生物制药有限公司 一种雷扎芬净纯化方法
CN116903706B (zh) * 2023-06-13 2024-05-17 深圳市祥根生物有限公司 一种棘白菌素类药物及其制备方法和用途

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Also Published As

Publication number Publication date
US20160075740A1 (en) 2016-03-17
US20220162263A1 (en) 2022-05-26
HUS2400021I1 (hu) 2024-07-28
LT2680873T (lt) 2017-11-27
WO2012119065A3 (en) 2014-03-13
CA2865791A1 (en) 2012-09-07
FR24C1027I2 (fr) 2025-05-23
US9217014B2 (en) 2015-12-22
US9676821B2 (en) 2017-06-13
PT2680873T (pt) 2017-11-01
US12344680B2 (en) 2025-07-01
US20250289852A1 (en) 2025-09-18
EP2680873A4 (en) 2015-08-26
JP2014516339A (ja) 2014-07-10
CN106279369B (zh) 2020-02-11
CY1119709T1 (el) 2018-06-27
DK2680873T3 (en) 2017-10-30
EP3192803B1 (en) 2020-12-09
CA3053850A1 (en) 2012-09-07
HUE036778T2 (hu) 2018-07-30
WO2012119065A2 (en) 2012-09-07
CA2865791C (en) 2019-10-08
CN103889221B (zh) 2016-08-31
NL301280I2 (nl) 2024-08-01
CN106279369A (zh) 2017-01-04
NO2680873T3 (it) 2018-01-06
SI2680873T1 (sl) 2017-12-29
US20170253635A1 (en) 2017-09-07
LTPA2024520I1 (it) 2024-07-10
FIC20240022I1 (fi) 2024-06-19
JP2016029052A (ja) 2016-03-03
HRP20171579T1 (hr) 2018-02-09
CN103889221A (zh) 2014-06-25
ES2645074T3 (es) 2017-12-04
RS56426B1 (sr) 2018-01-31
JP6111447B2 (ja) 2017-04-12
EP3192803A1 (en) 2017-07-19
US20130244930A1 (en) 2013-09-19
US8722619B2 (en) 2014-05-13
PL2680873T3 (pl) 2018-01-31
EP2680873B1 (en) 2017-08-09
HRP20171579T8 (hr) 2018-12-14
EP2680873A2 (en) 2014-01-08
ES2645074T8 (es) 2018-09-28
CY2024022I1 (el) 2025-03-28
JP5809296B2 (ja) 2015-11-10
FR24C1027I1 (fr) 2024-08-30
JP6302108B2 (ja) 2018-03-28
CY2024022I2 (el) 2025-03-28
US20150024997A1 (en) 2015-01-22
JP2018118977A (ja) 2018-08-02
JP2017132770A (ja) 2017-08-03

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