SMT201700545T1 - Composizioni e metodi per superare la resistenza al tramadolo - Google Patents

Composizioni e metodi per superare la resistenza al tramadolo

Info

Publication number: SMT201700545T1
Authority: SM; San Marino
Prior art keywords: tramadol; compositions; methods; overcoming resistance; overcoming
Prior art date: 2011-07-09

Application number

SM20170545T

Other languages

English (en)

Inventor

John A Zebala

Original Assignee

Syntrix Biosystems Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-07-09

Filing date

2012-07-09

Publication date

2018-01-11

2012-07-09 Application filed by Syntrix Biosystems Inc filed Critical Syntrix Biosystems Inc

2018-01-11 Publication of SMT201700545T1 publication Critical patent/SMT201700545T1/it

Links

TVYLLZQTGLZFBW-ZBFHGGJFSA-N (R,R)-tramadol Chemical compound COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-ZBFHGGJFSA-N 0.000 title 1
239000000203 mixture Substances 0.000 title 1
229960004380 tramadol Drugs 0.000 title 1
TVYLLZQTGLZFBW-GOEBONIOSA-N tramadol Natural products COC1=CC=CC([C@@]2(O)[C@@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-GOEBONIOSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Physiology (AREA)
Nutrition Science (AREA)
Hematology (AREA)
Obesity (AREA)
Addiction (AREA)
Psychiatry (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Pain & Pain Management (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Compositions Of Macromolecular Compounds (AREA)

SM20170545T 2011-07-09 2012-07-09 Composizioni e metodi per superare la resistenza al tramadolo SMT201700545T1 (it)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201161506092P	2011-07-09	2011-07-09
EP12810860.2A EP2729134B1 (en)	2011-07-09	2012-07-09	Compositions and methods for overcoming resistance to tramadol
PCT/US2012/045885 WO2013009666A1 (en)	2011-07-09	2012-07-09	Compositions and methods for overcoming resistance to tramadol

Publications (1)

Publication Number	Publication Date
SMT201700545T1 true SMT201700545T1 (it)	2018-01-11

Family

ID=47438792

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SM20170545T SMT201700545T1 (it)	2011-07-09	2012-07-09	Composizioni e metodi per superare la resistenza al tramadolo

Country Status (15)

Country	Link
US (6)	US10702485B2 (it)
EP (2)	EP2729134B1 (it)
CY (1)	CY1119597T1 (it)
DK (1)	DK2729134T3 (it)
ES (1)	ES2650368T3 (it)
HR (1)	HRP20171743T1 (it)
HU (1)	HUE037341T2 (it)
LT (1)	LT2729134T (it)
NO (1)	NO2833973T3 (it)
PL (1)	PL2729134T3 (it)
PT (1)	PT2729134T (it)
RS (1)	RS56570B1 (it)
SI (1)	SI2729134T1 (it)
SM (1)	SMT201700545T1 (it)
WO (1)	WO2013009666A1 (it)

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CA3024081A1 (en) *	2015-05-11	2016-11-17	Demerx, Inc.	Methods for treatment of opioid dependency and withdrawal using noribogaine
US11000488B2 (en)	2019-03-22	2021-05-11	Syntrix Biosystems Inc.	Treating pain using desmetramadol
CN113861048A (zh) *	2020-06-30	2021-12-31	南京诺瑞特医药科技有限公司	去甲曲马多的盐及其用途

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2012
- 2012-07-08 US US13/543,883 patent/US10702485B2/en active Active
- 2012-07-09 PL PL12810860T patent/PL2729134T3/pl unknown
- 2012-07-09 LT LTEP12810860.2T patent/LT2729134T/lt unknown
- 2012-07-09 ES ES12810860.2T patent/ES2650368T3/es active Active
- 2012-07-09 DK DK12810860.2T patent/DK2729134T3/en active
- 2012-07-09 HU HUE12810860A patent/HUE037341T2/hu unknown
- 2012-07-09 HR HRP20171743TT patent/HRP20171743T1/hr unknown
- 2012-07-09 EP EP12810860.2A patent/EP2729134B1/en active Active
- 2012-07-09 WO PCT/US2012/045885 patent/WO2013009666A1/en not_active Ceased
- 2012-07-09 RS RS20171178A patent/RS56570B1/sr unknown
- 2012-07-09 PT PT128108602T patent/PT2729134T/pt unknown
- 2012-07-09 EP EP17172870.2A patent/EP3272339A1/en not_active Withdrawn
- 2012-07-09 SI SI201231115T patent/SI2729134T1/sl unknown
- 2012-07-09 SM SM20170545T patent/SMT201700545T1/it unknown
2013
- 2013-04-05 NO NO13728551A patent/NO2833973T3/no unknown
2015
- 2015-08-07 US US14/821,506 patent/US9808432B2/en active Active
- 2015-11-23 US US14/949,434 patent/US9717700B2/en active Active
2016
- 2016-04-06 US US15/092,533 patent/US9717701B2/en active Active
2017
- 2017-07-27 US US15/662,189 patent/US20170319511A1/en not_active Abandoned
- 2017-07-27 US US15/662,160 patent/US20170319510A1/en not_active Abandoned
- 2017-11-08 CY CY20171101169T patent/CY1119597T1/el unknown

Also Published As

Publication number	Publication date
US9717701B2 (en)	2017-08-01
US9717700B2 (en)	2017-08-01
WO2013009666A1 (en)	2013-01-17
PT2729134T (pt)	2017-11-24
US20150342905A1 (en)	2015-12-03
HUE037341T2 (hu)	2018-08-28
EP2729134A4 (en)	2015-03-04
SI2729134T1 (sl)	2017-12-29
CY1119597T1 (el)	2018-04-04
NO2833973T3 (it)	2018-02-10
EP2729134B1 (en)	2017-08-23
PL2729134T3 (pl)	2018-01-31
US20170319511A1 (en)	2017-11-09
EP3272339A1 (en)	2018-01-24
US20160220514A1 (en)	2016-08-04
DK2729134T3 (en)	2017-10-09
US20130011444A1 (en)	2013-01-10
US20160074341A1 (en)	2016-03-17
US20170319510A1 (en)	2017-11-09
US10702485B2 (en)	2020-07-07
US9808432B2 (en)	2017-11-07
RS56570B1 (sr)	2018-02-28
LT2729134T (lt)	2017-10-10
HRP20171743T1 (hr)	2017-12-29
EP2729134A1 (en)	2014-05-14
ES2650368T3 (es)	2018-01-18

Publication	Publication Date	Title
SI2729134T1 (sl)	2017-12-29	Sestavki in postopki za premagovanje odpornosti proti tramadolu
GB201122195D0 (en)	2012-02-01	Composition and method
GB201408236D0 (en)	2014-06-25	Composition and method
GB201120616D0 (en)	2012-01-11	Composition
GB201411762D0 (en)	2014-08-13	Precoating methods and compositions
GB201119601D0 (en)	2011-12-28	Composition
GB201106357D0 (en)	2011-06-01	Composition and uses thereof
GB201106433D0 (en)	2011-06-01	Composition and method
ZA201308892B (en)	2016-08-31	Compositions and methods
ZA201401382B (en)	2015-11-25	Composition
LT2734186T (lt)	2018-12-10	Kompozicija
EP2726110A4 (en)	2015-07-01	COMPOSITIONS AND METHODS FOR METABOLIC IMAGING
GB201121258D0 (en)	2012-01-18	Composition
GB201115211D0 (en)	2011-10-19	Composition
GB201108912D0 (en)	2011-07-13	Composition
GB201103964D0 (en)	2011-04-20	Composition
GB201322023D0 (en)	2014-01-29	Composition
EP2711011A4 (en)	2014-11-05	COMPOSITION CONTAINING PANAXADIOL
GB201204957D0 (en)	2012-05-02	Composition
GB201216884D0 (en)	2012-11-07	Composition
ZA201203742B (en)	2013-02-27	Nutricosmetic composition
GB201118701D0 (en)	2011-12-14	Composition
GB201116340D0 (en)	2011-11-02	Compositions and methods
GB201107454D0 (en)	2011-06-15	Compositions and uses
GB201101924D0 (en)	2011-03-23	Compositions and uses