SMT202000440T1 - Trattamenti combinati comprendenti imidazopirazinoni per il trattamento di disturbi psichiatrici e/o cognitivi - Google Patents

Trattamenti combinati comprendenti imidazopirazinoni per il trattamento di disturbi psichiatrici e/o cognitivi

Info

Publication number
SMT202000440T1
SMT202000440T1 SM20200440T SMT202000440T SMT202000440T1 SM T202000440 T1 SMT202000440 T1 SM T202000440T1 SM 20200440 T SM20200440 T SM 20200440T SM T202000440 T SMT202000440 T SM T202000440T SM T202000440 T1 SMT202000440 T1 SM T202000440T1
Authority
SM
San Marino
Prior art keywords
imidazopyrazinones
psychiatric
treatment
cognitive disorders
combination treatments
Prior art date
Application number
SM20200440T
Other languages
English (en)
Inventor
Jan Kehler
Lars Kyhn Rasmussen
Mikkel Jessing
Karsten Juhl
Morten Langgård
Paulo Jorge Vieira Vital
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of SMT202000440T1 publication Critical patent/SMT202000440T1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SM20200440T 2016-10-28 2017-10-26 Trattamenti combinati comprendenti imidazopirazinoni per il trattamento di disturbi psichiatrici e/o cognitivi SMT202000440T1 (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201600659 2016-10-28
PCT/EP2017/077497 WO2018078038A1 (en) 2016-10-28 2017-10-26 Combination treatments comprising imidazopyrazinones for the treatment of psychiatric and/or cognitive disorders
EP17791080.9A EP3532064B1 (en) 2016-10-28 2017-10-26 Combination treatments comprising imidazopyrazinones for the treatment of psychiatric and/or cognitive disorders

Publications (1)

Publication Number Publication Date
SMT202000440T1 true SMT202000440T1 (it) 2020-09-10

Family

ID=60186299

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20200440T SMT202000440T1 (it) 2016-10-28 2017-10-26 Trattamenti combinati comprendenti imidazopirazinoni per il trattamento di disturbi psichiatrici e/o cognitivi

Country Status (30)

Country Link
US (1) US10905688B2 (it)
EP (1) EP3532064B1 (it)
JP (1) JP2019536762A (it)
KR (1) KR20190075068A (it)
CN (1) CN109803658A (it)
AR (1) AR109991A1 (it)
AU (1) AU2017350473A1 (it)
BR (1) BR112018013247A2 (it)
CA (1) CA3041607A1 (it)
CL (1) CL2019001091A1 (it)
CO (1) CO2019002909A2 (it)
CY (1) CY1123396T1 (it)
DK (1) DK3532064T3 (it)
ES (1) ES2816005T3 (it)
HR (1) HRP20201326T1 (it)
HU (1) HUE050403T2 (it)
IL (1) IL265635A (it)
LT (1) LT3532064T (it)
MA (1) MA46611B1 (it)
ME (1) ME03821B (it)
MX (1) MX2019004763A (it)
PL (1) PL3532064T3 (it)
PT (1) PT3532064T (it)
RS (1) RS60716B1 (it)
RU (1) RU2019109039A (it)
SG (1) SG11201903770UA (it)
SI (1) SI3532064T1 (it)
SM (1) SMT202000440T1 (it)
WO (1) WO2018078038A1 (it)
ZA (1) ZA201902091B (it)

Families Citing this family (7)

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TWI729109B (zh) 2016-04-12 2021-06-01 丹麥商Ｈ 朗德貝克公司 作爲PDE1抑制劑的1,5-二氫-4H-吡唑并[3,4-d]嘧啶-4-酮和1,5-二氫-4H-吡唑并[4,3-c]吡啶-4-酮
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BR112018013084A2 (pt) 2016-10-28 2018-12-11 H Lundbeck As tratamentos de combinação compreendendo a administração de imidazopirazinonas
SG11201903770UA (en) 2016-10-28 2019-05-30 H Lundbeck As Combination treatments comprising imidazopyrazinones for the treatment of psychiatric and/or cognitive disorders
MX2020008126A (es) 2018-02-01 2020-09-18 Japan Tobacco Inc Compuesto de amida heterociclica nitrogenada y su uso para fines medicos.

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BR112018013084A2 (pt) 2016-10-28 2018-12-11 H Lundbeck As tratamentos de combinação compreendendo a administração de imidazopirazinonas

Also Published As

Publication number Publication date
CL2019001091A1 (es) 2019-07-05
HUE050403T2 (hu) 2020-12-28
CY1123396T1 (el) 2021-12-31
RU2019109039A3 (it) 2021-01-29
CO2019002909A2 (es) 2019-06-19
ME03821B (me) 2021-04-20
PL3532064T3 (pl) 2020-11-16
MA46611A (fr) 2019-09-04
ES2816005T3 (es) 2021-03-31
DK3532064T3 (da) 2020-08-24
KR20190075068A (ko) 2019-06-28
ZA201902091B (en) 2020-10-28
CN109803658A (zh) 2019-05-24
LT3532064T (lt) 2020-09-25
US10905688B2 (en) 2021-02-02
IL265635A (en) 2019-05-30
SI3532064T1 (sl) 2020-10-30
HRP20201326T1 (hr) 2020-11-27
RS60716B1 (sr) 2020-09-30
SG11201903770UA (en) 2019-05-30
EP3532064B1 (en) 2020-07-29
US20190282571A1 (en) 2019-09-19
AR109991A1 (es) 2019-02-13
CA3041607A1 (en) 2018-05-03
MA46611B1 (fr) 2020-08-31
WO2018078038A1 (en) 2018-05-03
EP3532064A1 (en) 2019-09-04
AU2017350473A1 (en) 2019-04-18
RU2019109039A (ru) 2020-11-30
MX2019004763A (es) 2019-07-01
PT3532064T (pt) 2020-09-03
BR112018013247A2 (pt) 2018-12-04
JP2019536762A (ja) 2019-12-19

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