SU460622A3 - Способ получени замещенной бензолсульфонилмочевины - Google Patents

Способ получени замещенной бензолсульфонилмочевины

Info

Publication number: SU460622A3
Authority: SU; USSR - Soviet Union
Prior art keywords: preparing substituted; benzenesulfonylurea; substituted; substituted benzenesulfonylurea; bicyclo
Prior art date: 1967-08-10

Application number

SU1615624A

Other languages

English (en)

Inventor

Аумюллер Вальтер

Вебер Хельмут

Мут Карл

Вайер Руди

Original Assignee

Фарбверке Хехст Аг (Фирма)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1967-08-10

Filing date

1968-08-10

Publication date

1975-02-15

1968-08-10 Application filed by Фарбверке Хехст Аг (Фирма) filed Critical Фарбверке Хехст Аг (Фирма)

1975-02-15 Application granted granted Critical

1975-02-15 Publication of SU460622A3 publication Critical patent/SU460622A3/ru

Links

GHDLZGOOOLEJKI-UHFFFAOYSA-N benzenesulfonylurea Chemical class NC(=O)NS(=O)(=O)C1=CC=CC=C1 GHDLZGOOOLEJKI-UHFFFAOYSA-N 0.000 title description 5
238000000034 method Methods 0.000 title description 4
-1 BENZENESULPHONYL Chemical class 0.000 description 4
125000000217 alkyl group Chemical group 0.000 description 3
125000003545 alkoxy group Chemical group 0.000 description 2
125000005083 alkoxyalkoxy group Chemical group 0.000 description 2
125000001475 halogen functional group Chemical group 0.000 description 2
150000002431 hydrogen Chemical class 0.000 description 2
239000001257 hydrogen Substances 0.000 description 2
229910052739 hydrogen Inorganic materials 0.000 description 2
125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
239000005977 Ethylene Substances 0.000 description 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
235000001484 Trigonella foenum graecum Nutrition 0.000 description 1
244000250129 Trigonella foenum graecum Species 0.000 description 1
125000002252 acyl group Chemical group 0.000 description 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 description 1
239000003054 catalyst Substances 0.000 description 1
239000000460 chlorine Substances 0.000 description 1
229910052801 chlorine Inorganic materials 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
125000000753 cycloalkyl group Chemical group 0.000 description 1
125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 description 1
125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
125000002071 phenylalkoxy group Chemical group 0.000 description 1
125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Description

(54) СПОСОБ ПОЛУЧЕНИЯ ЗАМЕЩЕННОЙ БЕНЗОЛСУЛЬФОНИЛМОЧЕВИНЫ

1

Изобретение относитс к способу получени НОВОЙ замещенной бензолсульфонилмочевины ИЛИ ее солей, которые могут быть использованы в качестве биологически активных соединений .

Известен способ получени замещенной бензолсульфонилмочевины формулы

//

SOiNH-CO-i HR,

X-CO-NU-Yгде RI - алкил или циклоалкил; X - замещенный фенил; -этиленова или метилэтиленова группа, гидрированием соответственно замещенной бензолсульфонилмочевины, содержащей двойную св зь, молекул рным водородом в присутствии известного катализатора .

Однако необходимость в синтезе других замещенных бензолсульфонилмочевины, обладающих лучшими по сравнению с известными свойствами, в насто щее врем не тер ет овоей актуальности.

По предложенному способу получают новую замещенную бензолсульфонилмочевины общей формулы

SO NH-CO-KHR

где RI - 4,7 - эндометилен нергидроиндан-5ил , который в положении 6 может быть замещен хлором; 4,7-эндометилеБпергидроиндан-2ил; 2,6-эндометиленциклогептил; норкаран-7ил; бицикло-(5Д,0)-октил-18; бицикло-(6,1,0)нонил-9; бицикло-(4,2,0)-октил-7; 2,5-эндоциклобутилен- (1,2)-циклогексил; мети лци клоп ентил; 3,3-диметилциклопентил; 3-этилциклопентил; З-ТуОет-бутилдиклопентил; 2-хлорциклопентил; бицикло-(2,1,1)-гексил-2; спиро-2-циклопропаепентил; спиро-2-циклобутанпентил; спиро-2-ц.иклопентанпентил; циклопропил; циклобутил; бицикло-(3,1,0)-гексил;

X - а) фенил, замещенный в любом положении одинаковыми или разными Z и Ъ, где Z - циан, нитрогруппа, водород, галоид, низший алкил, алкокси, алкоксиалкокси, или оксигруппа; Zi - водород, галоид, низший алкил, трифторметил, алкокси, алкоксиалкокси, фенилалкоксигруппа , низший ацил, бензоил. оксигруппа;

SU1615624A 1967-08-10 1968-08-10 Способ получени замещенной бензолсульфонилмочевины SU460622A3 (ru)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DEF0053202		1967-08-10

Publications (1)

Publication Number	Publication Date
SU460622A3 true SU460622A3 (ru)	1975-02-15

Family

ID=7106084

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
SU1615624A SU460622A3 (ru)	1967-08-10	1968-08-10	Способ получени замещенной бензолсульфонилмочевины
SU1647219A SU404232A3 (ru)	1967-08-10	1968-08-10
SU1615146A SU400086A3 (ru)	1967-08-10	1968-08-10
SU1650165A SU399115A3 (ru)	1967-08-10	1968-08-10

Family Applications After (3)

Application Number	Title	Priority Date
SU1647219A SU404232A3 (ru)	1967-08-10	1968-08-10
SU1615146A SU400086A3 (ru)	1967-08-10	1968-08-10
SU1650165A SU399115A3 (ru)	1967-08-10	1968-08-10

Country Status (21)

Country	Link
AR (4)	AR193491A1 (ru)
AT (2)	AT319263B (ru)
CH (5)	CH522610A (ru)
CY (1)	CY585A (ru)
DK (1)	DK132946C (ru)
ES (1)	ES357107A1 (ru)
FI (1)	FI50115C (ru)
FR (2)	FR1598160A (ru)
GB (1)	GB1194790A (ru)
IL (1)	IL30431A (ru)
IS (1)	IS767B6 (ru)
IT (1)	IT1053691B (ru)
LU (1)	LU56488A1 (ru)
MC (1)	MC725A1 (ru)
MY (1)	MY7100109A (ru)
NL (1)	NL163778C (ru)
NO (1)	NO126685B (ru)
OA (1)	OA02877A (ru)
PL (1)	PL84736B1 (ru)
SE (1)	SE352345B (ru)
SU (4)	SU460622A3 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE791638A (fr) *	1971-11-20	1973-05-21	Hoechst Ag	Sulfonyl-urees, leur procede de preparation et leurs applications
DK455480A (da) *	1979-11-30	1981-05-31	Du Pont	Fremgangsmaade til fremstilling af herbicide n- (substituerede heterocycliske aminocarbonyl)-aromatiske sulfonamider

1968
- 1968-07-15 AT AT06800/68A patent/AT319263B/de not_active IP Right Cessation
- 1968-07-15 LU LU56488D patent/LU56488A1/xx unknown
- 1968-07-15 AT AT308073A patent/AT321316B/de not_active IP Right Cessation
- 1968-07-16 CH CH33971A patent/CH522610A/de not_active IP Right Cessation
- 1968-07-16 CH CH371372A patent/CH522614A/de not_active IP Right Cessation
- 1968-07-16 CH CH33871A patent/CH522609A/de not_active IP Right Cessation
- 1968-07-16 CH CH1062168A patent/CH506500A/de not_active IP Right Cessation
- 1968-07-16 FI FI682028A patent/FI50115C/fi active
- 1968-07-16 CH CH371472A patent/CH522615A/de not_active IP Right Cessation
- 1968-07-16 NO NO02818/68A patent/NO126685B/no unknown
- 1968-07-17 SE SE09781/68A patent/SE352345B/xx unknown
- 1968-07-25 IL IL30431A patent/IL30431A/xx unknown
- 1968-08-05 PL PL1968128491A patent/PL84736B1/pl unknown
- 1968-08-08 NL NL6811279.A patent/NL163778C/xx active
- 1968-08-09 IS IS1759A patent/IS767B6/is unknown
- 1968-08-09 ES ES357107A patent/ES357107A1/es not_active Expired
- 1968-08-09 DK DK386868A patent/DK132946C/da active
- 1968-08-09 MC MC771A patent/MC725A1/fr unknown
- 1968-08-09 OA OA53352A patent/OA02877A/xx unknown
- 1968-08-09 IT IT20028/68A patent/IT1053691B/it active
- 1968-08-10 SU SU1615624A patent/SU460622A3/ru active
- 1968-08-10 SU SU1647219A patent/SU404232A3/ru active
- 1968-08-10 SU SU1615146A patent/SU400086A3/ru active
- 1968-08-10 SU SU1650165A patent/SU399115A3/ru active
- 1968-08-12 FR FR1598160D patent/FR1598160A/fr not_active Expired
- 1968-08-12 GB GB38468/68A patent/GB1194790A/en not_active Expired
- 1968-11-08 FR FR173083A patent/FR8094M/fr not_active Expired
1969
- 1969-12-02 AR AR225660A patent/AR193491A1/es active
- 1969-12-02 AR AR225656A patent/AR192552A1/es active
- 1969-12-02 AR AR225658A patent/AR193338A1/es active
1971
- 1971-04-22 CY CY58571A patent/CY585A/xx unknown
- 1971-08-13 AR AR237385A patent/AR196978A1/es active
- 1971-12-31 MY MY1971109A patent/MY7100109A/xx unknown

Also Published As

Publication number	Publication date
CH522614A (de)	1972-05-15
SU400086A3 (ru)	1973-10-03
IS1759A7 (is)	1969-02-11
SU435610A3 (ru)	1974-07-05
CH522610A (de)	1972-05-15
SE352345B (ru)	1972-12-27
FI50115C (fi)	1975-12-10
NL6811279A (ru)	1969-02-12
IL30431A (en)	1974-09-10
NL163778C (nl)	1980-10-15
CH522615A (de)	1972-05-15
LU56488A1 (ru)	1970-01-15
AR193338A1 (es)	1973-04-23
DK132946B (da)	1976-03-01
NO126685B (ru)	1973-03-12
ES357107A1 (es)	1970-03-01
AT319263B (de)	1974-12-10
FI50115B (ru)	1975-09-01
CH506500A (de)	1971-04-30
CH522609A (de)	1972-05-15
AR193491A1 (es)	1973-04-30
SU404232A3 (ru)	1973-10-26
AT321316B (de)	1975-03-25
GB1194790A (en)	1970-06-10
IS767B6 (is)	1970-12-18
CY585A (en)	1971-04-22
SU399115A3 (ru)	1973-09-27
IT1053691B (it)	1981-10-10
MY7100109A (en)	1971-12-31
FR8094M (ru)	1970-07-20
MC725A1 (fr)	1969-05-20
SU437277A3 (ru)	1974-07-25
DK132946C (da)	1976-08-16
FR1598160A (ru)	1970-07-06
PL84736B1 (en)	1976-04-30
IL30431A0 (en)	1968-09-26
NL163778B (nl)	1980-05-16
AR192552A1 (es)	1973-02-28
AR196978A1 (es)	1974-03-08
OA02877A (fr)	1970-12-15

Publication	Publication Date	Title
GB1034196A (en)	1966-06-29	Fluorocarbon ether-acids and derivatives thereof, and their preparation
SU460622A3 (ru)	1975-02-15	Способ получени замещенной бензолсульфонилмочевины
Gilman et al.	1943	Organostrontium Compounds1
GB545001A (en)	1942-05-06	Active contact masses
KR910002749A (ko)	1991-02-26	할로겐-교환 방법
GB1150620A (en)	1969-04-30	2-Substituted-N-Acyloxyazolidines
US2366452A (en)	1945-01-02	Process of preparing condensation products
US2410469A (en)	1946-11-05	Aryl alkyl amino alkanes and compositions thereof
US2553495A (en)	1951-05-15	N-(3-benzothenyl)-n-ethyl-betachloroethylamine adrenolytic
GB1074491A (en)	1967-07-05	Novel processes for preparing steroid compounds, the compounds when thus prepared, novel steroid compounds thereby prepared, and pharmaceutical compositions containing the novel compounds
US2280818A (en)	1942-04-28	Process for the catalytic production of olefin-sulphur dioxide compounds of high molecular weight
DE1063146B (de)	1959-08-13	Verfahren zur Herstellung von Carbaminsaeureestern
DE69607568T2 (de)	2000-09-14	Verfahren zur Herstellung von Additionsprodukten aus Aminen und Alpha-Beta ungesättigten Verbindungen
US2227400A (en)	1940-12-31	Process for preparing acylamino nitro diphenyl sulphones
Linstead et al.	1934	127. Catalytic influences in three-carbon tautomerism. Part III. A review of possible mechanisms, and further examination of catalysis by alkoxides
US2628233A (en)	1953-02-10	Substituted and unsubstituted barbiturates and thiobarbiturates of 1, 2, 3-trisubstituted pyrazolones and processes of producing such compositions
DE683801C (de)	1939-11-16	Verfahren zur Herstellung substituierter Amide fettaromatischer Monocarbonsaeuren
Garraway	1962	796. The addition of N-alkyl-substituted dithiocarbamic and alkoxydithioformic acids to propiolic acid
GB1104945A (en)	1968-03-06	Substituted cycloalkylamines
Stitt et al.	1954	The Oxidation of Di-t-butylpyrogallol by Oxygen in Alkaline Solution. II. Absorption Spectra of the Products
SU652163A1 (ru)	1979-03-15	Способ получени диолефиновых углеводородов
ES311024A1 (es)	1965-07-01	Procedimiento para preparar sulfamidas.
US2785168A (en)	1957-03-12	Ethyl 1-methyl-4-phenylisonipecotate nu-oxides
US2824133A (en)	1958-02-18	Monohydrate of alpha methoxyisobutyric acid
SU131757A1 (ru)	1960-11-30	Способ получени метилтиоцианата