SU468410A3 - Способ получени производных нитрофуриламидина - Google Patents

Способ получени производных нитрофуриламидина

Info

Publication number: SU468410A3
Authority: SU; USSR - Soviet Union
Prior art keywords: furyl; derivatives; triazolo; pyridazine; nitro
Prior art date: 1970-06-20

Application number

SU1842000A

Other languages

English (en)

Russian (ru)

Inventor

Бергер Херберт

Галл Руди

Тил Макс

Фемель Вольфганг

Зауер Винфриде

Original Assignee

Берингер Маннхайм Гмбх (Фирма)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-06-20

Filing date

1971-06-18

Publication date

1975-04-25

1971-06-18 Application filed by Берингер Маннхайм Гмбх (Фирма) filed Critical Берингер Маннхайм Гмбх (Фирма)

1975-04-25 Application granted granted Critical

1975-04-25 Publication of SU468410A3 publication Critical patent/SU468410A3/ru

Links

238000000034 method Methods 0.000 title description 6
-1 nitrofuryl amidine Chemical class 0.000 description 13
PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical compound C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 description 10
150000001875 compounds Chemical class 0.000 description 6
125000000217 alkyl group Chemical group 0.000 description 4
RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 3
WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 description 3
150000001412 amines Chemical class 0.000 description 3
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 description 2
229910052739 hydrogen Inorganic materials 0.000 description 2
239000001257 hydrogen Substances 0.000 description 2
125000004433 nitrogen atom Chemical group N* 0.000 description 2
229910052760 oxygen Inorganic materials 0.000 description 2
239000001301 oxygen Substances 0.000 description 2
150000003839 salts Chemical class 0.000 description 2
229910052717 sulfur Inorganic materials 0.000 description 2
FLBAYUMRQUHISI-UHFFFAOYSA-N 1,8-naphthyridine Chemical compound N1=CC=CC2=CC=CN=C21 FLBAYUMRQUHISI-UHFFFAOYSA-N 0.000 description 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
RLAHWVDQYNDAGG-UHFFFAOYSA-N Methanetriol Chemical compound OC(O)O RLAHWVDQYNDAGG-UHFFFAOYSA-N 0.000 description 1
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
239000002253 acid Substances 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
125000004183 alkoxy alkyl group Chemical group 0.000 description 1
125000003545 alkoxy group Chemical group 0.000 description 1
230000000844 anti-bacterial effect Effects 0.000 description 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
238000000354 decomposition reaction Methods 0.000 description 1
125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
230000000694 effects Effects 0.000 description 1
MPAYEWNVIPXRDP-UHFFFAOYSA-N ethanimine Chemical class CC=N MPAYEWNVIPXRDP-UHFFFAOYSA-N 0.000 description 1
150000002431 hydrogen Chemical class 0.000 description 1
125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
150000002463 imidates Chemical class 0.000 description 1
230000003993 interaction Effects 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
239000000155 melt Substances 0.000 description 1
125000005358 mercaptoalkyl group Chemical group 0.000 description 1
150000007522 mineralic acids Chemical class 0.000 description 1
239000000203 mixture Substances 0.000 description 1
230000003472 neutralizing effect Effects 0.000 description 1
229910052757 nitrogen Inorganic materials 0.000 description 1
231100000252 nontoxic Toxicity 0.000 description 1
230000003000 nontoxic effect Effects 0.000 description 1
150000007523 nucleic acids Chemical group 0.000 description 1
102000039446 nucleic acids Human genes 0.000 description 1
108020004707 nucleic acids Proteins 0.000 description 1
150000007524 organic acids Chemical class 0.000 description 1
235000005985 organic acids Nutrition 0.000 description 1
125000004430 oxygen atom Chemical group O* 0.000 description 1
229910052698 phosphorus Inorganic materials 0.000 description 1
239000011574 phosphorus Substances 0.000 description 1
239000002798 polar solvent Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
238000001953 recrystallisation Methods 0.000 description 1
239000007858 starting material Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
238000006467 substitution reaction Methods 0.000 description 1
239000011593 sulfur Substances 0.000 description 1
125000004434 sulfur atom Chemical group 0.000 description 1
239000000725 suspension Substances 0.000 description 1
150000003852 triazoles Chemical class 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SU1842000A 1970-06-20 1971-06-18 Способ получени производных нитрофуриламидина SU468410A3 (ru)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19702030581 DE2030581A1 (de)	1970-06-20	1970-06-20	Nitrofuryl-amidin-Derivate und Verfahren zur Herstellung derselben

Publications (1)

Publication Number	Publication Date
SU468410A3 true SU468410A3 (ru)	1975-04-25

Family

ID=5774553

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
SU1842000A SU468410A3 (ru)	1970-06-20	1971-06-18	Способ получени производных нитрофуриламидина
SU1677748A SU421188A3 (ru)	1970-06-20	1971-06-18	Способ получения производных нитрофурил (или тиенил) амидина
SU1842826A SU455534A3 (ru)	1970-06-20	1971-06-18	Способ получени производных нитрофуриламидина или нитротиениламидина

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
SU1677748A SU421188A3 (ru)	1970-06-20	1971-06-18	Способ получения производных нитрофурил (или тиенил) амидина
SU1842826A SU455534A3 (ru)	1970-06-20	1971-06-18	Способ получени производных нитрофуриламидина или нитротиениламидина

Country Status (11)

Country	Link
AT (3)	AT309407B (de)
CA (1)	CA942304A (de)
DE (1)	DE2030581A1 (de)
ES (1)	ES392288A1 (de)
FR (1)	FR2100800B1 (de)
GB (1)	GB1309727A (de)
IE (1)	IE35388B1 (de)
NL (1)	NL7108264A (de)
SE (1)	SE372769B (de)
SU (3)	SU468410A3 (de)
ZA (1)	ZA713906B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2222834A1 (de) *	1972-05-10	1973-11-29	Boehringer Mannheim Gmbh	Nitrofuryl-amidin-derivate und verfahren zur herstellung derselben
HUE030390T2 (en)	2005-12-21	2017-05-29	Janssen Pharmaceutica Nv	Triazolopyridazines as tyrosine kinase modulators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1485277A (fr) *	1965-07-02	1967-06-16	Boehringer & Soehne Gmbh	Procédé pour la préparation de nouveaux composés 5-nitrofuryle et 5-nitrothiényle
US3658796A (en) *	1968-04-10	1972-04-25	Boehringer Mannheim Gmbh	5-nitrofuran derivatives

1970
- 1970-06-20 DE DE19702030581 patent/DE2030581A1/de active Pending
1971
- 1971-06-15 ZA ZA713906A patent/ZA713906B/xx unknown
- 1971-06-16 ES ES392288A patent/ES392288A1/es not_active Expired
- 1971-06-16 NL NL7108264A patent/NL7108264A/xx unknown
- 1971-06-16 GB GB2821771A patent/GB1309727A/en not_active Expired
- 1971-06-18 SU SU1842000A patent/SU468410A3/ru active
- 1971-06-18 IE IE789/71A patent/IE35388B1/xx unknown
- 1971-06-18 CA CA116,103A patent/CA942304A/en not_active Expired
- 1971-06-18 AT AT127272A patent/AT309407B/de not_active IP Right Cessation
- 1971-06-18 FR FR7122199A patent/FR2100800B1/fr not_active Expired
- 1971-06-18 AT AT127172A patent/AT309406B/de not_active IP Right Cessation
- 1971-06-18 SU SU1677748A patent/SU421188A3/ru active
- 1971-06-18 SU SU1842826A patent/SU455534A3/ru active
- 1971-06-18 AT AT530171A patent/AT304520B/de not_active IP Right Cessation
- 1971-06-18 SE SE7107953A patent/SE372769B/xx unknown

Also Published As

Publication number	Publication date
FR2100800A1 (de)	1972-03-24
IE35388L (en)	1971-12-20
IE35388B1 (en)	1976-02-04
NL7108264A (de)	1971-12-22
SE372769B (de)	1975-01-13
AT304520B (de)	1973-01-10
AT309406B (de)	1973-08-27
SU455534A3 (ru)	1974-12-30
GB1309727A (en)	1973-03-14
FR2100800B1 (de)	1975-10-10
ES392288A1 (es)	1973-10-01
CA942304A (en)	1974-02-19
ZA713906B (en)	1972-02-23
AT309407B (de)	1973-08-27
SU421188A3 (ru)	1974-03-25
DE2030581A1 (de)	1971-12-30

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