SU578864A3 - Способ получени 2-амино-2 адамантилуксусной кислоты - Google Patents
Способ получени 2-амино-2 адамантилуксусной кислотыInfo
- Publication number
- SU578864A3 SU578864A3 SU7502136595A SU2136595A SU578864A3 SU 578864 A3 SU578864 A3 SU 578864A3 SU 7502136595 A SU7502136595 A SU 7502136595A SU 2136595 A SU2136595 A SU 2136595A SU 578864 A3 SU578864 A3 SU 578864A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- mol
- ether
- adamantyl
- solution
- carbamate
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 4
- 239000002253 acid Substances 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 17
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 14
- 239000000243 solution Substances 0.000 claims 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 6
- 239000000047 product Substances 0.000 claims 5
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims 4
- 238000009835 boiling Methods 0.000 claims 4
- 238000002360 preparation method Methods 0.000 claims 4
- LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 claims 4
- NWZSZGALRFJKBT-KNIFDHDWSA-N (2s)-2,6-diaminohexanoic acid;(2s)-2-hydroxybutanedioic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O.NCCCC[C@H](N)C(O)=O NWZSZGALRFJKBT-KNIFDHDWSA-N 0.000 claims 3
- 238000010438 heat treatment Methods 0.000 claims 3
- IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 claims 3
- 238000002329 infrared spectrum Methods 0.000 claims 3
- 229910052757 nitrogen Inorganic materials 0.000 claims 3
- 239000011541 reaction mixture Substances 0.000 claims 3
- VOWMKAWURROZJG-UHFFFAOYSA-N 2-(2-amino-2-adamantyl)acetic acid Chemical compound C1C(C2)CC3CC1C(N)(CC(O)=O)C2C3 VOWMKAWURROZJG-UHFFFAOYSA-N 0.000 claims 2
- BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 claims 2
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims 2
- 230000001476 alcoholic effect Effects 0.000 claims 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 2
- 238000001816 cooling Methods 0.000 claims 2
- 239000012259 ether extract Substances 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 238000002844 melting Methods 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- 239000002244 precipitate Substances 0.000 claims 2
- 238000001953 recrystallisation Methods 0.000 claims 2
- 235000010288 sodium nitrite Nutrition 0.000 claims 2
- 238000003756 stirring Methods 0.000 claims 2
- -1 2 adamantyl cyanoacetylhydrazide Chemical compound 0.000 claims 1
- GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 claims 1
- IJJJSNBMFDDFBC-UHFFFAOYSA-N 2-cyanoethyl acetate Chemical compound CC(=O)OCCC#N IJJJSNBMFDDFBC-UHFFFAOYSA-N 0.000 claims 1
- 125000001731 2-cyanoethyl group Chemical group [H]C([H])(*)C([H])([H])C#N 0.000 claims 1
- BWWXRNTZXODDHO-UHFFFAOYSA-N CC(=O)OCC(C#N)C1C2CC3CC(C2)CC1C3 Chemical compound CC(=O)OCC(C#N)C1C2CC3CC(C2)CC1C3 BWWXRNTZXODDHO-UHFFFAOYSA-N 0.000 claims 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 1
- 239000005977 Ethylene Substances 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 125000002877 alkyl aryl group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 239000013078 crystal Substances 0.000 claims 1
- 238000001704 evaporation Methods 0.000 claims 1
- 230000008020 evaporation Effects 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 239000000706 filtrate Substances 0.000 claims 1
- 150000004678 hydrides Chemical class 0.000 claims 1
- 230000007062 hydrolysis Effects 0.000 claims 1
- 238000006460 hydrolysis reaction Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 238000006386 neutralization reaction Methods 0.000 claims 1
- 230000003472 neutralizing effect Effects 0.000 claims 1
- HLNRBHDRGMNBEG-UHFFFAOYSA-N nitrous acid Chemical compound ON=O.ON=O HLNRBHDRGMNBEG-UHFFFAOYSA-N 0.000 claims 1
- 238000010992 reflux Methods 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 238000001228 spectrum Methods 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| YU01353/74A YU36365B (en) | 1974-05-16 | 1974-05-16 | Process for preparing alpha-amino-2-adamantyl acetic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU578864A3 true SU578864A3 (ru) | 1977-10-30 |
Family
ID=25553818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU7502136595A SU578864A3 (ru) | 1974-05-16 | 1975-05-15 | Способ получени 2-амино-2 адамантилуксусной кислоты |
Country Status (5)
| Country | Link |
|---|---|
| AT (1) | AT336562B (de) |
| CH (1) | CH612172A5 (de) |
| DE (1) | DE2521894A1 (de) |
| SU (1) | SU578864A3 (de) |
| YU (1) | YU36365B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9901691D0 (en) * | 1999-01-26 | 1999-03-17 | Cerebrus Ltd | Chemical compounds |
-
1974
- 1974-05-16 YU YU01353/74A patent/YU36365B/xx unknown
-
1975
- 1975-05-06 CH CH584075A patent/CH612172A5/xx not_active IP Right Cessation
- 1975-05-13 AT AT362675A patent/AT336562B/de not_active IP Right Cessation
- 1975-05-15 SU SU7502136595A patent/SU578864A3/ru active
- 1975-05-16 DE DE19752521894 patent/DE2521894A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE2521894A1 (de) | 1975-12-04 |
| YU36365B (en) | 1983-06-30 |
| AT336562B (de) | 1977-05-10 |
| ATA362675A (de) | 1976-09-15 |
| YU135374A (en) | 1981-11-13 |
| CH612172A5 (en) | 1979-07-13 |
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