SU884569A3 - Способ получени 20-метил-13,14-дидегидро-pGI -производных или их солей - Google Patents
Способ получени 20-метил-13,14-дидегидро-pGI -производных или их солей Download PDFInfo
- Publication number
- SU884569A3 SU884569A3 SU792790905A SU2790905A SU884569A3 SU 884569 A3 SU884569 A3 SU 884569A3 SU 792790905 A SU792790905 A SU 792790905A SU 2790905 A SU2790905 A SU 2790905A SU 884569 A3 SU884569 A3 SU 884569A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- methyl
- derivatives
- didehydro
- hydrogen
- pgl2
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 7
- 239000001257 hydrogen Substances 0.000 claims abstract description 5
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 5
- 150000001875 compounds Chemical class 0.000 claims abstract description 4
- 150000001768 cations Chemical class 0.000 claims abstract description 3
- 238000006704 dehydrohalogenation reaction Methods 0.000 claims abstract description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract description 3
- 150000003839 salts Chemical class 0.000 claims description 5
- 125000001246 bromo group Chemical group Br* 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 125000002346 iodo group Chemical group I* 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract description 3
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract description 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract description 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract description 2
- 229910052794 bromium Inorganic materials 0.000 abstract description 2
- 239000003795 chemical substances by application Substances 0.000 abstract description 2
- 239000000460 chlorine Substances 0.000 abstract description 2
- 229910052801 chlorine Inorganic materials 0.000 abstract description 2
- 239000011630 iodine Substances 0.000 abstract description 2
- 229910052740 iodine Inorganic materials 0.000 abstract description 2
- 101100297345 Caenorhabditis elegans pgl-2 gene Proteins 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- -1 potassium alkoxide Chemical class 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
- 239000003513 alkali Substances 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT25903/78A IT1099575B (it) | 1978-07-20 | 1978-07-20 | 20-metil-13,14-deidro-pgi2' suoi sali e suoi 16s- e 16r-metil derivati |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU884569A3 true SU884569A3 (ru) | 1981-11-23 |
Family
ID=11218084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU792790905A SU884569A3 (ru) | 1978-07-20 | 1979-07-19 | Способ получени 20-метил-13,14-дидегидро-pGI -производных или их солей |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS5517389A (da) |
| AT (1) | AT367758B (da) |
| AU (1) | AU520750B2 (da) |
| BE (1) | BE877687A (da) |
| CA (1) | CA1183531A (da) |
| CH (1) | CH640522A5 (da) |
| CS (1) | CS208668B2 (da) |
| DE (1) | DE2922110A1 (da) |
| DK (1) | DK304479A (da) |
| FR (1) | FR2431492A1 (da) |
| GB (1) | GB2025972B (da) |
| HU (1) | HU182727B (da) |
| IE (1) | IE48593B1 (da) |
| IL (1) | IL57552A (da) |
| IT (1) | IT1099575B (da) |
| NL (1) | NL7905259A (da) |
| NO (1) | NO792313L (da) |
| SE (1) | SE446002B (da) |
| SU (1) | SU884569A3 (da) |
| YU (1) | YU152979A (da) |
| ZA (1) | ZA793123B (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3029984C2 (de) | 1980-08-08 | 1983-12-15 | Grünenthal GmbH, 5190 Stolberg | 2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL51189A (en) * | 1976-02-04 | 1985-08-30 | Upjohn Co | Prostaglandin analogs |
| AU3583378A (en) * | 1977-06-06 | 1979-11-08 | Chicago The University Of | Prostacyclin analogs |
-
1978
- 1978-07-20 IT IT25903/78A patent/IT1099575B/it active
-
1979
- 1979-05-31 DE DE19792922110 patent/DE2922110A1/de not_active Withdrawn
- 1979-06-13 IL IL57552A patent/IL57552A/xx unknown
- 1979-06-13 AU AU48034/79A patent/AU520750B2/en not_active Ceased
- 1979-06-14 FR FR7915298A patent/FR2431492A1/fr active Granted
- 1979-06-20 AT AT0435479A patent/AT367758B/de not_active IP Right Cessation
- 1979-06-22 ZA ZA793123A patent/ZA793123B/xx unknown
- 1979-06-27 YU YU01529/79A patent/YU152979A/xx unknown
- 1979-07-05 NL NL7905259A patent/NL7905259A/nl not_active Application Discontinuation
- 1979-07-11 NO NO792313A patent/NO792313L/no unknown
- 1979-07-13 BE BE0/196287A patent/BE877687A/fr not_active IP Right Cessation
- 1979-07-19 HU HU79EA195A patent/HU182727B/hu unknown
- 1979-07-19 SU SU792790905A patent/SU884569A3/ru active
- 1979-07-19 DK DK304479A patent/DK304479A/da not_active Application Discontinuation
- 1979-07-19 SE SE7906234A patent/SE446002B/sv unknown
- 1979-07-19 CA CA000332125A patent/CA1183531A/en not_active Expired
- 1979-07-20 CH CH677779A patent/CH640522A5/de not_active IP Right Cessation
- 1979-07-20 CS CS795112A patent/CS208668B2/cs unknown
- 1979-07-20 GB GB7925488A patent/GB2025972B/en not_active Expired
- 1979-07-20 JP JP9172979A patent/JPS5517389A/ja active Pending
- 1979-08-08 IE IE1360/79A patent/IE48593B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE791360L (en) | 1980-01-20 |
| DE2922110A1 (de) | 1980-01-31 |
| AU4803479A (en) | 1980-01-24 |
| FR2431492A1 (fr) | 1980-02-15 |
| IL57552A (en) | 1983-02-23 |
| IE48593B1 (en) | 1985-03-20 |
| AU520750B2 (en) | 1982-02-25 |
| IT1099575B (it) | 1985-09-18 |
| BE877687A (fr) | 1980-01-14 |
| SE446002B (sv) | 1986-08-04 |
| CH640522A5 (de) | 1984-01-13 |
| CA1183531A (en) | 1985-03-05 |
| SE7906234L (sv) | 1980-01-21 |
| YU152979A (en) | 1983-01-21 |
| ATA435479A (de) | 1981-12-15 |
| NO792313L (no) | 1980-01-22 |
| NL7905259A (nl) | 1980-01-22 |
| IT7825903A0 (it) | 1978-07-20 |
| JPS5517389A (en) | 1980-02-06 |
| HU182727B (en) | 1984-03-28 |
| GB2025972A (en) | 1980-01-30 |
| IL57552A0 (en) | 1979-10-31 |
| AT367758B (de) | 1982-07-26 |
| GB2025972B (en) | 1982-09-15 |
| CS208668B2 (en) | 1981-09-15 |
| ZA793123B (en) | 1980-06-25 |
| DK304479A (da) | 1980-01-21 |
| FR2431492B1 (da) | 1982-07-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU528275B2 (en) | Imidazole derivatives | |
| DE3271269D1 (en) | Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same | |
| IE45574L (en) | Piperidyl-indole derivatives | |
| CA2221110A1 (en) | Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents for the treatment of ocular hypertension | |
| IL38972A (en) | Substituted phenyl alkanol derivatives,their preparation and compositions containing them | |
| CA1115700A (en) | .omega.-nor-aromatic-13,14-dehydro prostaglandins and process for their preparation | |
| GB1216945A (en) | Novel imidazoline derivatives, the preparation thereof and compositions containing the same | |
| CA1218649A (en) | .delta..sup.8,.sup.9-prostaglandin derivatives, process for their manufacture and their use as medicaments | |
| MX9304140A (es) | Sal de purina, proceso para su preparacion y proceso para preparar un agente antiviral mediante la reaccion de dicha sal. | |
| GB1502232A (en) | Substituted 2-phenylimino-1,3-dithiolanes process for their preparation and their use as ectoparasiticidal agents | |
| IE791360L (en) | 20-methyl-13,14-didehydro-pgi2 derivatives | |
| HUP9603150A2 (hu) | Szulfonil-amino-benzoil-guanidin-származékok, eljárás előállításukra és az e vegyületeket tartalmazó gyógyszerkészítmények | |
| GB1385563A (en) | Aminophthalazine derivatives and pharmaceutical uses thereof | |
| KR880701240A (ko) | 페니실란산 유도체의 신규한 개선된 제조방법 | |
| CA1155459A (en) | Decaprenylamine derivatives | |
| KR840001122A (ko) | 플루오르화 디아미노-헵텐 및-헵틴 유도체의 제조방법 | |
| ZA811499B (en) | Substituted propanols,process for their preparation,pharmaceutical compositions containing these | |
| ES8205395A1 (es) | Procedimiento para preparar nuevos 1-(acilamino-ariloxi-)2- hidroxi-3-alquinilaminopropanos | |
| EP0053379A1 (en) | Anti-peptic ulcer agent | |
| IE44764L (en) | Ferrocene derivatives. | |
| GB1293741A (en) | Improvements in or relating to thiazole derivatives | |
| GB1187200A (en) | 2-[(Halophenoxy) Methyl]-2-Imidazolines | |
| GB1503962A (en) | 2-(halo-vinyl(or ethynyl))-5-nitro furans and their use as microbiocides | |
| GB1223649A (en) | PROCESS FOR THE PREPARATION OF 2-(1'-H-HALOGENOALKYL-delta<2>-OXAZOLINES | |
| JPS54112847A (en) | Preparation of novel 3alpha, 6alpha-dihydroxy-24-oxo-5beta-cholestane |