SV2017005395A - Moduladores de pirrolopiridina de rorc2 sustituidos con metilo y trifluorometilo y métodos de uso de los mismos - Google Patents

Moduladores de pirrolopiridina de rorc2 sustituidos con metilo y trifluorometilo y métodos de uso de los mismos

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Publication number
SV2017005395A
SV2017005395A SV2017005395A SV2017005395A SV2017005395A SV 2017005395 A SV2017005395 A SV 2017005395A SV 2017005395 A SV2017005395 A SV 2017005395A SV 2017005395 A SV2017005395 A SV 2017005395A SV 2017005395 A SV2017005395 A SV 2017005395A
Authority
SV
El Salvador
Prior art keywords
methods
trifluorometile
replaced
pirrolopiridine
rorc2
Prior art date
Application number
SV2017005395A
Other languages
English (en)
Inventor
Andrew Christopher Flick
Peter Jones
Neelu Kaila
Scot Richard Mente
Mark Edward Schnute
John David Trzupek
Michael L Vazquez
Li Xing
Liying Zhang
Göran Mattias Wennerstål
Edouard Zamaratski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SV2017005395A publication Critical patent/SV2017005395A/es

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Mechanical Engineering (AREA)
  • Animal Husbandry (AREA)
  • Polymers & Plastics (AREA)
  • Environmental Sciences (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Food Science & Technology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Ceramic Engineering (AREA)
  • Zoology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)

Abstract

LA PRESENTE INVENCIÓN PROPORCIONA PIRROLOPIRIDINAS SUSTITUIDAS CON METILO Y TRIFLUOROMETILO, SUS COMPOSICIONES FARMACÉUTICAS, MÉTODOS PARA MODULAR LA ACTIVIDAD DE RORY Y/O REDUCIR LA CANTIDAD DE IL-17 EN UN SUJETO, Y MÉTODOS DE TRATAMIENTO DE DIVERSOS TRASTORNOS MÉDICOS UTILIZANDO TALES PIRROLOPIRIDINAS Y SUS COMPOSICIONES FARMACÉUTICAS
SV2017005395A 2014-09-26 2017-03-01 Moduladores de pirrolopiridina de rorc2 sustituidos con metilo y trifluorometilo y métodos de uso de los mismos SV2017005395A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462055811P 2014-09-26 2014-09-26
US201562110048P 2015-01-30 2015-01-30
US201562209124P 2015-08-24 2015-08-24

Publications (1)

Publication Number Publication Date
SV2017005395A true SV2017005395A (es) 2017-07-10

Family

ID=54292857

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2017005395A SV2017005395A (es) 2014-09-26 2017-03-01 Moduladores de pirrolopiridina de rorc2 sustituidos con metilo y trifluorometilo y métodos de uso de los mismos

Country Status (33)

Country Link
US (5) US9670201B2 (es)
EP (1) EP3197882A1 (es)
JP (1) JP6224870B2 (es)
KR (1) KR101933328B1 (es)
CN (1) CN106715416B (es)
AP (1) AP2017009800A0 (es)
AU (2) AU2015323380B2 (es)
BR (2) BR122017023934A2 (es)
CA (1) CA2905407A1 (es)
CL (1) CL2017000716A1 (es)
CO (1) CO2017002427A2 (es)
CR (1) CR20170108A (es)
CU (1) CU24407B1 (es)
DO (1) DOP2017000087A (es)
EA (1) EA030635B1 (es)
GE (2) GEAP201814455A (es)
GT (1) GT201700063A (es)
IL (1) IL250675A0 (es)
MA (1) MA40759A (es)
MD (1) MD20170027A2 (es)
MX (1) MX2017003956A (es)
NI (1) NI201700031A (es)
NZ (1) NZ729252A (es)
PE (1) PE20170703A1 (es)
PH (1) PH12017500494A1 (es)
SG (1) SG11201701329QA (es)
SV (1) SV2017005395A (es)
TN (1) TN2017000074A1 (es)
TW (1) TWI583685B (es)
UA (1) UA119569C2 (es)
UY (1) UY36322A (es)
WO (1) WO2016046755A1 (es)
ZA (2) ZA201701292B (es)

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MA40759A (fr) 2014-09-26 2017-08-01 Pfizer Modulateurs de rorc2 de type pyrrolopyridine substitué par un méthyle et trifluorométhyle et leurs procédés d'utilisation
JP2018510131A (ja) 2015-01-30 2018-04-12 ファイザー・インク Ｒｏｒｃ２のスルホンアミド置換インドールモジュレーターおよびその使用方法
US10336748B2 (en) 2015-01-30 2019-07-02 Pfizer Inc. Methyoxy-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof
TWI728017B (zh) 2015-12-15 2021-05-21 瑞典商阿斯特捷利康公司 異吲哚化合物、包含其之醫藥組成物及其用途
CN105753866A (zh) * 2016-04-05 2016-07-13 叶芳 一种4-卤素-7-氮杂吲哚及其制备方法
US20200087390A1 (en) 2016-12-21 2020-03-19 Amgen Inc. Anti-tnf alpha antibody formulations
EP3638661A1 (en) 2017-06-14 2020-04-22 Astrazeneca AB 2,3-dihydroisoindole-1-carboxamides useful as ror-gamma modulators
CN109206401B (zh) * 2017-06-29 2021-03-05 南京柯菲平盛辉制药有限公司 一类甲基-1H-吲唑类RORγ调节剂及其用途
KR20200094493A (ko) 2019-01-30 2020-08-07 김남형 음성사후분포그램추출기와 tts 및 보코더를 이용한 음성 변조 어플리케이션의 동작방법
WO2021220183A1 (en) * 2020-04-30 2021-11-04 Janssen Pharmaceutica Nv Imidazopyrimidines as modulators of il-17
CN114591137B (zh) * 2022-05-10 2022-09-09 上海赛默罗生物科技有限公司 螺桨烷类衍生物的合成方法
WO2023232870A1 (en) 2022-05-31 2023-12-07 Immunic Ag Rorg/rorgt modulators for the treatment of virus infections like covid-19
WO2025222170A1 (en) * 2024-04-19 2025-10-23 Zb17 Llc Methods of treatment
CN119119032B (zh) * 2024-08-05 2025-09-09 中山大学附属第三医院 一种吲哚苯甲酰胺类衍生物及其制备方法和应用

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