TH149193A - Pyrazolopyrimidine compounds and their use as PDE 10 inhibitors - Google Patents

Abstract

DC60 (20/10/16) This invention relates to the compounds represented by formula [I], where: R1 is a hydrogen, halogen, lower alkyl, or cyano; ring A is a potentially substituted heterocyclic group; ring B is a potentially substituted 3 to 6 member monocyclic group; and Y is a potentially substituted amino, potentially substituted cyclic amino, potentially substituted 3 to 6 member aliphatic monocyclic oxy, potentially substituted lower alkyl, or potentially substituted lower alkyl-O-, or a pharmaceutically acceptable salt thereof, and relates to their use as PDE10 (phosphodiesterase 10) inhibitors. Amended 20/10/2016 This invention relates to the compounds represented by formula [I], where: R1 is a hydrogen, halogen, lower alkyl, or cyano; Ring A is a potentially substituted heterocyclic group; ring B is a potentially substituted monocyclic group of 3 to 6 members; and Y is a potentially substituted amino, potentially substituted cyclic amino, potentially substituted aliphatic monocyclic oxy 3 to 6 members, potentially substituted lower alkyl or lower alkyl-O-, or a chemically acceptable salt thereof, and related to their use as PDE10 (phosphodiesterase 10) inhibitors. -------------------------- The present invention relates to the compounds represented by formula [I], where: R1 is a hydrogen, halogen, small alkyl, or cyano; ring A is a potentially substituted heterocyclic group; ring B is a potentially substituted monocyclic group of 3 to 6 members; And Y is a potentially substituted amino, potentially substituted cyclic amino, potentially substituted aliphatic monocyclic oxy 3 to 6 member potentially substituted, small potentially substituted alkyl, or small possibly substituted alkyl-O-, or a pharmaceutically accepted salt thereof and relevant to their use as PDE10 inhibitors.