TH553A - Manufacturing process N-Pirimidinil-Carbamic Acid Esters And mixtures containing these substances - Google Patents
Manufacturing process N-Pirimidinil-Carbamic Acid Esters And mixtures containing these substancesInfo
- Publication number
- TH553A TH553A TH8101000304A TH8101000304A TH553A TH 553 A TH553 A TH 553A TH 8101000304 A TH8101000304 A TH 8101000304A TH 8101000304 A TH8101000304 A TH 8101000304A TH 553 A TH553 A TH 553A
- Authority
- TH
- Thailand
- Prior art keywords
- carbamic acid
- formula
- acid esters
- mixtures containing
- pirimidinil
- Prior art date
Links
- 239000000126 substance Substances 0.000 title claims 5
- 239000000203 mixture Substances 0.000 title abstract 2
- 229940112021 centrally acting muscle relaxants carbamic acid ester Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940079593 drug Drugs 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- KYARBIJYVGJZLB-UHFFFAOYSA-N 7-amino-4-hydroxy-2-naphthalenesulfonic acid Chemical class OC1=CC(S(O)(=O)=O)=CC2=CC(N)=CC=C21 KYARBIJYVGJZLB-UHFFFAOYSA-N 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- -1 chloroformic acid ester Chemical class 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 230000000144 pharmacologic effect Effects 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- JOYRKODLDBILNP-UHFFFAOYSA-N urethane group Chemical group NC(=O)OCC JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 abstract 1
- 229960001082 trimethoprim Drugs 0.000 abstract 1
Abstract
กรรมวิธีในการผลิต 2-คาร์บามิค แอซิด เอสเทอร์ของ 2,4-ไดอะมิโน-5-(3'', 4'', 5''-ไทรเมธอกซีเบนซิล)-พิริมิดีน (ไทรเม- โธพริม) และสารผสมซึ่งมีสารเหล่านี้เป็นองค์ประกอบ ใช้เป็น โพร-ดรักส์ ของไทรเมโธพริม มีคุณสมบัติที่มีคุณค่าสามารถต่อ ต้านแบคทีเรียและเพิ่มฤทธิ์ให้แก่ซัลโฟนามีด สิทธิบัตรยา Process for producing 2- carbamic acid ester of 2,4-diamin-5- (3 '', 4 '', 5 '' - trimethoxybenzyl ) - Pyrimidine (trime-thoprim) and mixtures containing them as constituents are used as the trymethoprim's promethoprim Has valuable properties, can be further Antibacterial and enhances the effect of sulfonamides, patent drugs
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH553A true TH553A (en) | 1982-09-03 |
Family
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