TJ270B - 5,6-Dichlorobenzimidazole derivatives process for their preparation pharmaceutical composition and method of treatment or prophylaxis of virus infections - Google Patents

5,6-Dichlorobenzimidazole derivatives process for their preparation pharmaceutical composition and method of treatment or prophylaxis of virus infections

Info

Publication number
TJ270B
TJ270B TJ97000433A TJ97000433A TJ270B TJ 270 B TJ270 B TJ 270B TJ 97000433 A TJ97000433 A TJ 97000433A TJ 97000433 A TJ97000433 A TJ 97000433A TJ 270 B TJ270 B TJ 270B
Authority
TJ
Tajikistan
Prior art keywords
dichlorobenzimidazole
prophylaxis
treatment
pharmaceutical composition
virus infections
Prior art date
Application number
TJ97000433A
Other languages
English (en)
Inventor
Stanley Dawes Chamberlain
George Walter Koszalka
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of TJ270B publication Critical patent/TJ270B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
TJ97000433A 1994-07-07 1995-07-06 5,6-Dichlorobenzimidazole derivatives process for their preparation pharmaceutical composition and method of treatment or prophylaxis of virus infections TJ270B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9413724A GB9413724D0 (en) 1994-07-07 1994-07-07 Therapeutic nucleosides
PCT/GB1995/001597 WO1996001833A1 (en) 1994-07-07 1995-07-06 Therapeutic compounds

Publications (1)

Publication Number Publication Date
TJ270B true TJ270B (en) 2000-08-07

Family

ID=10757983

Family Applications (1)

Application Number Title Priority Date Filing Date
TJ97000433A TJ270B (en) 1994-07-07 1995-07-06 5,6-Dichlorobenzimidazole derivatives process for their preparation pharmaceutical composition and method of treatment or prophylaxis of virus infections

Country Status (43)

Country Link
US (4) US6077832A (cs)
EP (1) EP0769017B1 (cs)
JP (1) JP3225045B2 (cs)
KR (1) KR100376075B1 (cs)
CN (2) CN1052010C (cs)
AP (1) AP736A (cs)
AT (1) ATE193298T1 (cs)
AU (1) AU702248B2 (cs)
BG (1) BG63435B1 (cs)
BR (1) BR9508237A (cs)
CY (1) CY2249B1 (cs)
CZ (1) CZ290800B6 (cs)
DE (1) DE69517172T2 (cs)
DK (1) DK0769017T3 (cs)
EE (1) EE03568B1 (cs)
ES (1) ES2147294T3 (cs)
FI (1) FI117629B (cs)
GB (1) GB9413724D0 (cs)
GE (1) GEP20002298B (cs)
GR (1) GR3033744T3 (cs)
HR (1) HRP950382B1 (cs)
HU (1) HU227679B1 (cs)
IL (1) IL114492A (cs)
IS (1) IS1812B (cs)
MD (1) MD1838G2 (cs)
MX (1) MX9606732A (cs)
MY (1) MY117892A (cs)
NO (1) NO308854B1 (cs)
NZ (1) NZ288722A (cs)
OA (1) OA10339A (cs)
PL (1) PL181136B1 (cs)
PT (1) PT769017E (cs)
RO (1) RO117699B1 (cs)
RU (1) RU2145963C1 (cs)
SA (1) SA95160202B1 (cs)
SK (1) SK282046B6 (cs)
TJ (1) TJ270B (cs)
TR (1) TR199500832A2 (cs)
TW (1) TW418196B (cs)
UA (1) UA66744C2 (cs)
WO (1) WO1996001833A1 (cs)
YU (1) YU49443B (cs)
ZA (1) ZA955644B (cs)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9413724D0 (en) 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
EP0845001B1 (en) * 1995-08-18 2002-11-13 The Regents of The University of Michigan 5'-substituted-ribofuranosyl benzimidazoles as antiviral agents
GB9518465D0 (en) * 1995-09-09 1995-11-08 Smithkline Beecham Seiyaku Kk Pharmaceuticals
GB9600142D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Chemical compounds
GB9600143D0 (en) 1996-01-05 1996-03-06 Wellcome Found Therapeutic compounds
US6214801B1 (en) 1996-01-23 2001-04-10 The Regents Of The University Of Michigan Imidazo[1,2-a]pyridine C-nucleosides as antiviral agents
US6475388B1 (en) 1996-11-13 2002-11-05 Transgenomic, Inc. Method and system for RNA analysis by matched ion polynucleotide chromatography
US6576133B2 (en) 1996-11-13 2003-06-10 Transgenomic, Inc Method and system for RNA analysis by matched ion polynucleotide chromatography
GB2319961A (en) * 1996-12-07 1998-06-10 Glaxo Group Ltd Pharmaceutical composition for treatment of restenosis
AU6221998A (en) 1997-02-13 1998-09-08 Glaxo Group Limited Benzimidazole derivatives
DE69816992T2 (de) * 1997-06-10 2004-07-22 Glaxo Group Ltd., Greenford Benzimidazolderivate
AU744176B2 (en) 1997-07-30 2002-02-14 Glaxo Group Limited Lyxofuranosyl benzimidazoles as antiviral agents
US6258264B1 (en) 1998-04-10 2001-07-10 Transgenomic, Inc. Non-polar media for polynucleotide separations
GB9807355D0 (en) * 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
GB9807354D0 (en) * 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
US6277830B1 (en) * 1998-10-16 2001-08-21 Schering Corporation 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon
US6576265B1 (en) 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
GB0008939D0 (en) * 2000-04-11 2000-05-31 Glaxo Group Ltd Process for preparing substituted benzimidazole compounds
RU2262344C2 (ru) * 2001-07-25 2005-10-20 Дж.Б.Кемикалс Энд Фармасьютикалс Лтд. Фармацевтическая композиция для лечения кожных инфекций и способ ее получения
RU2366661C2 (ru) * 2002-06-28 2009-09-10 Айденикс (Кайман) Лимитед Пролекарства модифицированных 2'- и 3'-нуклеозидов для лечения инфекций flaviviridae
AU2004253508A1 (en) 2003-06-25 2005-01-13 Acell, Inc. Conditioned matrix compositions for tissue restoration
ES2377937T3 (es) * 2003-12-26 2012-04-03 Kissei Pharmaceutical Co., Ltd. Derivados de benzimidazol y usos médicos de los mismos
RU2268741C1 (ru) * 2004-08-04 2006-01-27 Государственное образовательное учреждение высшего профессионального образования "Южно-Уральский государственный университет" Способ лечения герпетического поражения вестибулярного, спирального, тригеминального и коленчатого ганглиев
WO2006115137A1 (ja) * 2005-04-22 2006-11-02 Kissei Pharmaceutical Co., Ltd. ２－アミノベンズイミダゾール誘導体及びその医薬用途
EA008737B1 (ru) * 2005-12-07 2007-08-31 Леонид Андреевич Кожемякин Средство для профилактики и лечения конъюнктивитов и кератитов различной этиологии (варианты), способ его применения
US8546344B2 (en) 2010-10-28 2013-10-01 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl)-1H-benzimidazole
US8541391B2 (en) 2010-10-28 2013-09-24 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl-1H-benzimidazole
US8940707B2 (en) * 2010-10-28 2015-01-27 Viropharma Incorporated Maribavir isomers, compositions, methods of making and methods of using
US9447050B2 (en) 2011-04-05 2016-09-20 The Translational Genomics Research Institute Solid forms of curcumin
US20140004307A1 (en) 2012-06-29 2014-01-02 The Procter & Gamble Company Textured Fibrous Webs, Apparatus And Methods For Forming Textured Fibrous Webs
US9650376B2 (en) 2013-03-15 2017-05-16 Knopp Biosciences Llc Imidazo(4,5-B) pyridin-2-yl amides as KV7 channel activators
SI3572405T1 (sl) 2014-09-12 2023-12-29 Biohaven Therapeutics Ltd. Amidi benzoimidazol-1,2-il kot aktivatorji kanalov kv 7
EP3223816B1 (en) * 2014-11-26 2020-04-22 The J. David Gladstone Institutes Methods for treating a cytomegalovirus infection
RU2629670C2 (ru) * 2016-08-04 2017-08-31 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) 2-Амино-5,6-дифтор-1-(бета-D-рибофуранозил)-бензимидазол, способ получения и противовирусная активность его в отношении вируса герпеса простого 1-го типа
CN118955402A (zh) 2018-03-19 2024-11-15 诺普生物科学有限责任公司 Kv7通道激活剂组合物和使用方法
US12043644B2 (en) * 2020-06-23 2024-07-23 Biometrix Technology Inc Benzimidazole derivatives, preparation method thereof and use thereof as anti-cancer agent or anti-virus agent comprising the same
CN119136799A (zh) 2022-10-12 2024-12-13 武田药品工业株式会社 制备马立巴韦的方法
WO2024103979A1 (zh) * 2022-11-17 2024-05-23 北京凯因科技股份有限公司 一种抑制疱疹病毒的化合物

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3399987A (en) * 1965-08-02 1968-09-03 United States Borax Chem 2-alkylaminobenzimidazoles as herbicides
CH443777A (de) * 1965-08-06 1968-02-15 Agripat Sa Verfahren zum Schützen textiler Keratinfasern vor Insektenfrass und Mittel zur Durchführung dieses Verfahrens
NL6716664A (cs) * 1966-12-19 1968-06-20
US3655901A (en) * 1970-07-30 1972-04-11 Merck & Co Inc Method of inhibiting the formation of phenylethanalamine-n-methyl transferase with 2-aminobenzimidazoles
DE2130030A1 (de) * 1971-06-18 1972-12-21 Bayer Ag Fungizide und bakterizide Mittel
US4002623A (en) * 1974-08-07 1977-01-11 Pfizer Inc. Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines
FR2549938B1 (fr) * 1983-07-25 1987-08-07 Fonderie Soc Gen De Bruleur a premelange gazeux et chaudiere equipee d'un tel bruleur
FR2551442B1 (fr) * 1983-09-05 1987-04-30 Centre Nat Rech Scient Nouveaux derives furaniques, leur preparation et leur application
CH667649A5 (en) * 1986-09-10 1988-10-31 Lonza Ag 2-Substd. amino-benzoxazole and -benzimidazole derivs. prodn. - by reacting prim. amino cpd. with amine in presence of acid catalyst, useful as intermediates e.g. for pharmaceuticals
EP0304624A3 (de) * 1987-07-29 1989-03-22 F. Hoffmann-La Roche Ag Benzimidazol-2-yl-pyridiniumverbindungen
IT1226100B (it) * 1988-07-07 1990-12-10 Dompe Farmaceutici Spa Derivati benzimidazolici farmacologicamente attivi.
DE3924424A1 (de) * 1989-07-24 1991-01-31 Boehringer Mannheim Gmbh Nucleosid-derivate, verfahren zu deren herstellung, deren verwendung als arzneimittel sowie deren verwendung bei der nucleinsaeure-sequenzierung
SE9003151D0 (sv) * 1990-10-02 1990-10-02 Medivir Ab Nucleoside derivatives
US5248672A (en) * 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
WO1992018517A1 (en) * 1991-04-17 1992-10-29 Yale University Method of treating or preventing hepatitis b virus
ZA923640B (en) * 1991-05-21 1993-02-24 Iaf Biochem Int Processes for the diastereoselective synthesis of nucleosides
ES2087962T3 (es) * 1991-09-04 1996-08-01 Stichting Rega V Z W Derivados nucleosidos sustituidos, metodos para su preparacion y composiciones farmaceuticas que los contienen.
US5314903A (en) * 1991-12-03 1994-05-24 Neurosearch A/S Benzimidazole compounds useful as calcium channel blockers
GB9205071D0 (en) * 1992-03-09 1992-04-22 Wellcome Found Therapeutic nucleosides
WO1994008456A1 (en) * 1992-10-21 1994-04-28 The Regents Of The University Of Michigan Polysubstituted benzimidazoles as antiviral agents
US5399580A (en) * 1993-03-08 1995-03-21 Burroughs Wellcome Co. Therapeutic nucleosides-uses
GB9413724D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
JP6217655B2 (ja) * 2015-01-15 2017-10-25 トヨタ自動車株式会社 電力変換装置

Also Published As

Publication number Publication date
SA95160202B1 (ar) 2005-04-16
RO117699B1 (ro) 2002-06-28
RU2145963C1 (ru) 2000-02-27
OA10339A (en) 1997-10-07
WO1996001833A1 (en) 1996-01-25
CZ290800B6 (cs) 2002-10-16
EP0769017B1 (en) 2000-05-24
MY117892A (en) 2004-08-30
DE69517172D1 (de) 2000-06-29
HU227679B1 (en) 2011-11-28
KR100376075B1 (ko) 2004-02-18
HK1003711A1 (en) 1998-11-06
ATE193298T1 (de) 2000-06-15
NO970040D0 (no) 1997-01-06
AU2805195A (en) 1996-02-09
HRP950382B1 (en) 2000-12-31
MX9606732A (es) 1997-04-30
PL318062A1 (en) 1997-05-12
EE03568B1 (et) 2001-12-17
CN1159194A (zh) 1997-09-10
US5998605A (en) 1999-12-07
NZ288722A (en) 1998-07-28
PT769017E (pt) 2000-09-29
FI970032L (fi) 1997-01-03
FI117629B (fi) 2006-12-29
CZ4097A3 (en) 1997-08-13
JP3225045B2 (ja) 2001-11-05
SK282046B6 (sk) 2001-10-08
IL114492A0 (en) 1995-11-27
FI970032A0 (fi) 1997-01-03
NO308854B1 (no) 2000-11-06
IS1812B (is) 2002-05-15
AP736A (en) 1999-03-09
DE69517172T2 (de) 2000-10-19
HUT77285A (hu) 1998-03-30
AU702248B2 (en) 1999-02-18
IS4394A (is) 1996-12-09
HU9700034D0 (en) 1997-02-28
MD1838G2 (ro) 2002-08-31
DK0769017T3 (da) 2000-09-11
TR199500832A2 (tr) 1996-06-21
NO970040L (no) 1997-01-29
YU49443B (sh) 2006-03-03
US6307043B1 (en) 2001-10-23
CY2249B1 (en) 2003-07-04
GEP20002298B (en) 2000-11-25
TW418196B (en) 2001-01-11
HRP950382A2 (en) 1997-08-31
UA66744C2 (en) 2004-06-15
US6077832A (en) 2000-06-20
BG63435B1 (bg) 2002-01-31
YU45095A (sh) 1999-03-04
US20010003744A1 (en) 2001-06-14
PL181136B1 (pl) 2001-06-29
BR9508237A (pt) 1999-06-01
MD1838F2 (en) 2002-01-31
CN1236616A (zh) 1999-12-01
SK168896A3 (en) 1997-09-10
JPH10502356A (ja) 1998-03-03
CN1052010C (zh) 2000-05-03
BG101118A (en) 1998-04-30
EE9700013A (et) 1997-06-16
EP0769017A1 (en) 1997-04-23
GR3033744T3 (en) 2000-10-31
ES2147294T3 (es) 2000-09-01
GB9413724D0 (en) 1994-08-24
IL114492A (en) 2002-05-23
ZA955644B (en) 1997-01-06
AP9600895A0 (en) 1997-01-31

Similar Documents

Publication Publication Date Title
TJ270B (en) 5,6-Dichlorobenzimidazole derivatives process for their preparation pharmaceutical composition and method of treatment or prophylaxis of virus infections
CS149192A3 (en) Pharmaceutical composition, process of its preparation and method offungal infections treating
IL121849A (en) 2-amino-4-phenylamino-6-substituted- 1,3,5-triazine derivatives, pharmaceutical compositions for treatment of hiv containing them and process for their preparation
AU4205789A (en) Method and composition for the treatment and prevention of viral infections
CZ56595A3 (en) Substituted thiazolidinedione derivatives, process of their preparation, pharmaceutical preparation in which they are comprised and their use
HUP9801599A3 (en) Use of imidazolin derivatives having alfa1l agonist effect for producing pharmaceutical compositions for treatment of incontinence, novel imidazolin derivatives and process for producing them
IL139658A0 (en) Pharmaceutical compositions for treatment and prophylaxis and method for their preparation
AU3636695A (en) Method, compositions, and apparatus for treating and preventing respiratory viral infections
PL299284A1 (en) Benzimidazole derivatives, method of obtaining them as well as pharmaceutical preparation and method of obtaining same
HUP9900680A3 (en) Acyclic nucleoside derivatives, process for producing them, pharmaceutical compositions containing them and method for the treatment of viral infections
HUP9903420A3 (en) Use of fluconazole for the preparation of pharmaceutical compositions, inhibiting the growth of cancers and treating viral infections
CZ346595A3 (en) Substituted derivatives of 4-phenylthiazoles, process of their preparation and pharmaceutical compositions containing thereof
KR950700310A (ko) 헤테로트리사이클릭 유도체, 그의 제조방법 및 그를 함유하는 약제학적 조성물(heterotricyclic derivatives, process for their preparation and pharmaceutical compositions containing them)
IL111338A0 (en) Pharmaceutical or veterinary compositions comprising flavin derivatives for the treatment of viral infections and their preparation
PL312491A1 (en) Novel benzoguanidine derivatives, method of obtaining them, their application for producing pharmaceutical agents, method of treating arrhytmia and pharmaceutical agent as such
CZ92295A3 (en) Boronpeptide derivatives, process of their preparation and pharmaceutical composition containing thereof
HUT64059A (en) Process for producing benzimidazole derivatives and pharmaceutical compositions comprising same
HU9502503D0 (en) 2,3-cyclic-condensed-1,4-dihydro-pyridine derivatives, process for producing them and pharmaceutical use of them
IL116925A (en) Combinations of compounds useful for treating HIV infections and pharmaceutical compositions comprising these combinations
EP0558961A3 (en) Glycopeptide derivatives, process for their manufacture and pharmaceutical compositions comprising them
FI945729L (fi) Aminosubstituoidut bentseenisulfonyyliureat ja -tioureat, menetelmä niiden valmistamiseksi ja niiden käyttö farmaseuttisina aineina
HU9401188D0 (en) 3-quinolyl-substituted dihydropyridine derivatives, process for producing them and use of them in pharmaceutical compositions
HUT68007A (en) Pharmaceutical compositions for preventing and treating retinal diseases and process for preparing them
FI965114A7 (fi) Farmaseuttinen koostumus virusinfektioiden sekä valinnaisesti tulehdusten estoon ja (tai) hoitoon sekä niiden hoitomenetelmä
ZA9510108B (en) Composition and method for prevention and treatment of HIV-1 infection