HUT77285A - Vírusellenes hatású benzimidazolszármazékok és e vegyületeket tartalmazó gyógyászati készítmények, valamint eljárás e vegyületek előállítására és közbenső termékeik - Google Patents

Vírusellenes hatású benzimidazolszármazékok és e vegyületeket tartalmazó gyógyászati készítmények, valamint eljárás e vegyületek előállítására és közbenső termékeik

Info

Publication number
HUT77285A
HUT77285A HU9700034A HU9700034A HUT77285A HU T77285 A HUT77285 A HU T77285A HU 9700034 A HU9700034 A HU 9700034A HU 9700034 A HU9700034 A HU 9700034A HU T77285 A HUT77285 A HU T77285A
Authority
HU
Hungary
Prior art keywords
compounds
intermediates
preparation
well
pharmaceutical compositions
Prior art date
Application number
HU9700034A
Other languages
English (en)
Other versions
HU9700034D0 (en
HU227679B1 (en
Inventor
Stanley Dawes Chamberlain
George Walter Koszalka
Original Assignee
The Wellcome Foundation Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Wellcome Foundation Limited filed Critical The Wellcome Foundation Limited
Publication of HU9700034D0 publication Critical patent/HU9700034D0/hu
Publication of HUT77285A publication Critical patent/HUT77285A/hu
Publication of HU227679B1 publication Critical patent/HU227679B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HU9700034A 1994-07-07 1995-07-06 Benzimidazole derivatives with antiviral activity, pharmaceutical compns. contg. them, process for preparing them and intermediates thereof HU227679B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9413724A GB9413724D0 (en) 1994-07-07 1994-07-07 Therapeutic nucleosides
PCT/GB1995/001597 WO1996001833A1 (en) 1994-07-07 1995-07-06 Therapeutic compounds

Publications (3)

Publication Number Publication Date
HU9700034D0 HU9700034D0 (en) 1997-02-28
HUT77285A true HUT77285A (hu) 1998-03-30
HU227679B1 HU227679B1 (en) 2011-11-28

Family

ID=10757983

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9700034A HU227679B1 (en) 1994-07-07 1995-07-06 Benzimidazole derivatives with antiviral activity, pharmaceutical compns. contg. them, process for preparing them and intermediates thereof

Country Status (43)

Country Link
US (4) US6077832A (hu)
EP (1) EP0769017B1 (hu)
JP (1) JP3225045B2 (hu)
KR (1) KR100376075B1 (hu)
CN (2) CN1052010C (hu)
AP (1) AP736A (hu)
AT (1) ATE193298T1 (hu)
AU (1) AU702248B2 (hu)
BG (1) BG63435B1 (hu)
BR (1) BR9508237A (hu)
CY (1) CY2249B1 (hu)
CZ (1) CZ290800B6 (hu)
DE (1) DE69517172T2 (hu)
DK (1) DK0769017T3 (hu)
EE (1) EE03568B1 (hu)
ES (1) ES2147294T3 (hu)
FI (1) FI117629B (hu)
GB (1) GB9413724D0 (hu)
GE (1) GEP20002298B (hu)
GR (1) GR3033744T3 (hu)
HR (1) HRP950382B1 (hu)
HU (1) HU227679B1 (hu)
IL (1) IL114492A (hu)
IS (1) IS1812B (hu)
MD (1) MD1838G2 (hu)
MX (1) MX9606732A (hu)
MY (1) MY117892A (hu)
NO (1) NO308854B1 (hu)
NZ (1) NZ288722A (hu)
OA (1) OA10339A (hu)
PL (1) PL181136B1 (hu)
PT (1) PT769017E (hu)
RO (1) RO117699B1 (hu)
RU (1) RU2145963C1 (hu)
SA (1) SA95160202B1 (hu)
SK (1) SK282046B6 (hu)
TJ (1) TJ270B (hu)
TR (1) TR199500832A2 (hu)
TW (1) TW418196B (hu)
UA (1) UA66744C2 (hu)
WO (1) WO1996001833A1 (hu)
YU (1) YU49443B (hu)
ZA (1) ZA955644B (hu)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9413724D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
ATE227734T1 (de) * 1995-08-18 2002-11-15 Univ Michigan 5'-substitutierte-ribofuranosyl benzimidazolen als antivirale.
GB9518465D0 (en) * 1995-09-09 1995-11-08 Smithkline Beecham Seiyaku Kk Pharmaceuticals
GB9600142D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Chemical compounds
GB9600143D0 (en) 1996-01-05 1996-03-06 Wellcome Found Therapeutic compounds
WO1997027205A1 (en) 1996-01-23 1997-07-31 The Regents Of The University Of Michigan Imidazo[1,2-a]pyridine c-nucleosides as antiviral agents
US6576133B2 (en) 1996-11-13 2003-06-10 Transgenomic, Inc Method and system for RNA analysis by matched ion polynucleotide chromatography
US6475388B1 (en) 1996-11-13 2002-11-05 Transgenomic, Inc. Method and system for RNA analysis by matched ion polynucleotide chromatography
GB2319961A (en) * 1996-12-07 1998-06-10 Glaxo Group Ltd Pharmaceutical composition for treatment of restenosis
WO1998035977A1 (en) 1997-02-13 1998-08-20 Glaxo Group Limited Benzimidazole derivatives
PT994890E (pt) 1997-06-10 2003-11-28 Glaxo Group Ltd Derivados de benzimidazole
EP1000080A1 (en) 1997-07-30 2000-05-17 The Regents of The University of Michigan Lyxofuranosyl benzimidazoles as antiviral agents
US6258264B1 (en) 1998-04-10 2001-07-10 Transgenomic, Inc. Non-polar media for polynucleotide separations
GB9807355D0 (en) 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
GB9807354D0 (en) 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
US6277830B1 (en) * 1998-10-16 2001-08-21 Schering Corporation 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon
US6576265B1 (en) 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
GB0008939D0 (en) * 2000-04-11 2000-05-31 Glaxo Group Ltd Process for preparing substituted benzimidazole compounds
RU2262344C2 (ru) * 2001-07-25 2005-10-20 Дж.Б.Кемикалс Энд Фармасьютикалс Лтд. Фармацевтическая композиция для лечения кожных инфекций и способ ее получения
RU2005102096A (ru) * 2002-06-28 2005-11-20 Айденикс (Кайман) Лимитед (Ky) 2'и 3'-нуклеозидные пролекарства для лечения инфекций, вызываемых flaviviridae
US20050025838A1 (en) 2003-06-25 2005-02-03 Badylak Stephen F. Conditioned compositions for tissue restoration
ATE537181T1 (de) * 2003-12-26 2011-12-15 Kissei Pharmaceutical Benzimidazolderivate und deren medizinische verwendungen
RU2268741C1 (ru) * 2004-08-04 2006-01-27 Государственное образовательное учреждение высшего профессионального образования "Южно-Уральский государственный университет" Способ лечения герпетического поражения вестибулярного, спирального, тригеминального и коленчатого ганглиев
JPWO2006115137A1 (ja) * 2005-04-22 2008-12-18 キッセイ薬品工業株式会社 ２−アミノベンズイミダゾール誘導体及びその医薬用途
EA008737B1 (ru) * 2005-12-07 2007-08-31 Леонид Андреевич Кожемякин Средство для профилактики и лечения конъюнктивитов и кератитов различной этиологии (варианты), способ его применения
US8541391B2 (en) 2010-10-28 2013-09-24 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl-1H-benzimidazole
US8546344B2 (en) 2010-10-28 2013-10-01 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl)-1H-benzimidazole
US8940707B2 (en) 2010-10-28 2015-01-27 Viropharma Incorporated Maribavir isomers, compositions, methods of making and methods of using
WO2012138907A2 (en) * 2011-04-05 2012-10-11 Translational Genomics Research Institute Solid forms of curcumin
US20140004307A1 (en) 2012-06-29 2014-01-02 The Procter & Gamble Company Textured Fibrous Webs, Apparatus And Methods For Forming Textured Fibrous Webs
ES2885424T3 (es) 2013-03-15 2021-12-13 Knopp Biosciences Llc Imidazo(4,5-B)piridin-2-il amidas como activadores del canal Kv7
ES2960991T3 (es) 2014-09-12 2024-03-07 Biohaven Therapeutics Ltd Benzoimidazol-1,2-ilamidas como activadores del canal Kv7
US10478431B2 (en) 2014-11-26 2019-11-19 The J. David Gladstone Institutes Methods for treating a cytomegalovirus infection
RU2629670C2 (ru) * 2016-08-04 2017-08-31 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) 2-Амино-5,6-дифтор-1-(бета-D-рибофуранозил)-бензимидазол, способ получения и противовирусная активность его в отношении вируса герпеса простого 1-го типа
IL310136A (en) 2018-03-19 2024-03-01 Knopp Biosciences Llc KV7 channel activator preparations and methods of use
JP7376108B2 (ja) * 2020-06-23 2023-11-08 バイオメトリックス テクノロジーズ インコーポレイテッド 新規なベンズイミダゾール誘導体、その製造方法及びその抗癌剤または抗ウイルス剤としての用途
PL4475844T3 (pl) 2022-10-12 2025-11-12 Takeda Pharmaceutical Company Limited Sposób otrzymywania maribawiru
WO2024103979A1 (zh) * 2022-11-17 2024-05-23 北京凯因科技股份有限公司 一种抑制疱疹病毒的化合物

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3399987A (en) * 1965-08-02 1968-09-03 United States Borax Chem 2-alkylaminobenzimidazoles as herbicides
CH443777A (de) * 1965-08-06 1968-02-15 Agripat Sa Verfahren zum Schützen textiler Keratinfasern vor Insektenfrass und Mittel zur Durchführung dieses Verfahrens
NL6716664A (hu) * 1966-12-19 1968-06-20
US3655901A (en) * 1970-07-30 1972-04-11 Merck & Co Inc Method of inhibiting the formation of phenylethanalamine-n-methyl transferase with 2-aminobenzimidazoles
DE2130030A1 (de) * 1971-06-18 1972-12-21 Bayer Ag Fungizide und bakterizide Mittel
US4002623A (en) * 1974-08-07 1977-01-11 Pfizer Inc. Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines
FR2549938B1 (fr) * 1983-07-25 1987-08-07 Fonderie Soc Gen De Bruleur a premelange gazeux et chaudiere equipee d'un tel bruleur
FR2551442B1 (fr) * 1983-09-05 1987-04-30 Centre Nat Rech Scient Nouveaux derives furaniques, leur preparation et leur application
CH667649A5 (en) * 1986-09-10 1988-10-31 Lonza Ag 2-Substd. amino-benzoxazole and -benzimidazole derivs. prodn. - by reacting prim. amino cpd. with amine in presence of acid catalyst, useful as intermediates e.g. for pharmaceuticals
EP0304624A3 (de) * 1987-07-29 1989-03-22 F. Hoffmann-La Roche Ag Benzimidazol-2-yl-pyridiniumverbindungen
IT1226100B (it) * 1988-07-07 1990-12-10 Dompe Farmaceutici Spa Derivati benzimidazolici farmacologicamente attivi.
DE3924424A1 (de) * 1989-07-24 1991-01-31 Boehringer Mannheim Gmbh Nucleosid-derivate, verfahren zu deren herstellung, deren verwendung als arzneimittel sowie deren verwendung bei der nucleinsaeure-sequenzierung
SE9003151D0 (sv) * 1990-10-02 1990-10-02 Medivir Ab Nucleoside derivatives
US5248672A (en) * 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
WO1992018517A1 (en) * 1991-04-17 1992-10-29 Yale University Method of treating or preventing hepatitis b virus
ZA923641B (en) * 1991-05-21 1993-02-24 Iaf Biochem Int Processes for the diastereoselective synthesis of nucleosides
DE69120069T2 (de) * 1991-09-04 1996-10-02 Consejo Superior Investigacion Substituierte Nukleosidderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US5314903A (en) * 1991-12-03 1994-05-24 Neurosearch A/S Benzimidazole compounds useful as calcium channel blockers
GB9205071D0 (en) * 1992-03-09 1992-04-22 Wellcome Found Therapeutic nucleosides
WO1994008456A1 (en) * 1992-10-21 1994-04-28 The Regents Of The University Of Michigan Polysubstituted benzimidazoles as antiviral agents
US5399580A (en) * 1993-03-08 1995-03-21 Burroughs Wellcome Co. Therapeutic nucleosides-uses
GB9413724D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
JP6217655B2 (ja) * 2015-01-15 2017-10-25 トヨタ自動車株式会社 電力変換装置

Also Published As

Publication number Publication date
PT769017E (pt) 2000-09-29
NO970040L (no) 1997-01-29
HU9700034D0 (en) 1997-02-28
BG101118A (en) 1998-04-30
AP9600895A0 (en) 1997-01-31
WO1996001833A1 (en) 1996-01-25
IL114492A (en) 2002-05-23
EE9700013A (et) 1997-06-16
EP0769017B1 (en) 2000-05-24
US6077832A (en) 2000-06-20
PL318062A1 (en) 1997-05-12
CN1159194A (zh) 1997-09-10
KR100376075B1 (ko) 2004-02-18
AU2805195A (en) 1996-02-09
OA10339A (en) 1997-10-07
FI970032A0 (fi) 1997-01-03
CZ290800B6 (cs) 2002-10-16
SK168896A3 (en) 1997-09-10
GEP20002298B (en) 2000-11-25
US5998605A (en) 1999-12-07
YU45095A (sh) 1999-03-04
ES2147294T3 (es) 2000-09-01
DE69517172D1 (de) 2000-06-29
HU227679B1 (en) 2011-11-28
CN1052010C (zh) 2000-05-03
RU2145963C1 (ru) 2000-02-27
TR199500832A2 (tr) 1996-06-21
MD1838G2 (ro) 2002-08-31
GR3033744T3 (en) 2000-10-31
TW418196B (en) 2001-01-11
AU702248B2 (en) 1999-02-18
YU49443B (sh) 2006-03-03
ATE193298T1 (de) 2000-06-15
CN1236616A (zh) 1999-12-01
MX9606732A (es) 1997-04-30
HRP950382B1 (en) 2000-12-31
UA66744C2 (en) 2004-06-15
MY117892A (en) 2004-08-30
MD1838F2 (en) 2002-01-31
FI970032L (fi) 1997-01-03
HK1003711A1 (en) 1998-11-06
CZ4097A3 (en) 1997-08-13
SK282046B6 (sk) 2001-10-08
IS1812B (is) 2002-05-15
NO308854B1 (no) 2000-11-06
NO970040D0 (no) 1997-01-06
EE03568B1 (et) 2001-12-17
RO117699B1 (ro) 2002-06-28
AP736A (en) 1999-03-09
CY2249B1 (en) 2003-07-04
GB9413724D0 (en) 1994-08-24
US6307043B1 (en) 2001-10-23
ZA955644B (en) 1997-01-06
BG63435B1 (bg) 2002-01-31
NZ288722A (en) 1998-07-28
IL114492A0 (en) 1995-11-27
DE69517172T2 (de) 2000-10-19
TJ270B (en) 2000-08-07
HRP950382A2 (en) 1997-08-31
IS4394A (is) 1996-12-09
BR9508237A (pt) 1999-06-01
US20010003744A1 (en) 2001-06-14
SA95160202B1 (ar) 2005-04-16
JP3225045B2 (ja) 2001-11-05
DK0769017T3 (da) 2000-09-11
FI117629B (fi) 2006-12-29
PL181136B1 (pl) 2001-06-29
EP0769017A1 (en) 1997-04-23
JPH10502356A (ja) 1998-03-03

Similar Documents

Publication Publication Date Title
FI962754L (fi) Uusia mahdollisesti substituoituja fenyyli-imidatsolidiineja, menetelmä niiden valmistamiseksi sekä valmistuksen välituotteita, niiden käyttö lääkkeinä ja niitä käsittävät farmaseuttiset koostumukset
FI903215A7 (fi) Heteroaryyliamino- ja heteroaryylioksipyridiiniamiineja ja niihin liittyviä yhdisteitä, menetelmä niiden valmistamiseksi sekä niiden käyttö lääkkeinä
FI942074L (fi) nor-sappijohdannaisia, menetelmä niiden valmistamiseksi ja näiden yhdisteiden käyttö lääkeaineina
HUP9601033A3 (en) Benzofurane derivatives, process for their preparation, use of them as intermediate and pharmaceutical compositions containing the compounds
FI954612L (fi) Uusia imidatsolidiinejä, jotka on substituoitu heterosyklillä, niiden valmistusmenetelmä ja -välituotetteita, niiden käyttö lääkkeinä ja niitä sisältävät farmaseuttiset koostumukset
EE9500059A (et) Asendatud 4-fenüül-6-aminonikotiinhappe derivaatide kasutamine ravimitena
FI952550A7 (fi) Uudet N-pyridyylikarboksamidit ja johdannaiset, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
FI931332A0 (fi) Uusia alkyleenidiammoniumdiklavulanaattijohdannaisia, menetelmä niidenvalmistamiseksi samoin kuin niiden käyttö kalvulaanihapon puhdistamiseksi
FI943688L (fi) Uudet 11-bentsaldoksiimi-17beta-metoksi-27alfa-metoksi-metyyli-estradieenijohdannaiset, menetelmät niiden valmistamiseksi ja näitä sisältävät lääkeaineet
IT8125291A0 (it) Composti xantati antivirali, procedimento per la loro produzione e composizioni farmaceutiche cheli contengono.
HUP9802393A3 (en) Benzothiazolone derivatives, their use, pharmaceutical compositions containing them, process for the preparation thereof and intermediates
HUT77375A (hu) Enterokinetikus hatású benzamidszármazékok, az ezeket tartalmazó gyógyszerkészítmények és eljárás a vegyületek előállítására
FI93106C (fi) Menetelmä lääkeaineina käyttökelpoisten 2-iminobentsotiatsoliinijohdannaisten valmistamiseksi
FI895983A0 (fi) Menetelmä lääkeaineina käyttökelpoisten 2-bentsotiatsoliinijohdannaisten valmistamiseksi
FI905192A7 (fi) Aminopyridinyyliaminofenolit ja vastaavat yhdisteet, menetelmä ja välituotteet niiden valmistamiseksi ja niiden käyttö lääkkeinä
IT8125570A0 (it) Composti ad attivita'antiinfiammatoria, processo per la loro preparazione e composizioni farmaceutiche relative
IT1194793B (it) Derivati tiazolidinici ad attivita' farmacologica,procedimento per la loro preparazione e composizioni farmaceutiche contenenti detti derivati
FI915875L (fi) Menetelmä yleisen kaavan I mukaisten lääkeaineina käyttökelpoisten 2,3-dihydro-4H-1,3-bentsoksatsinon-4-onien ja 2,3-dihydro-4H-bentsotiatsinon-4-onien nitro-oksijohdannaisten valmistamiseksi
FI940031L (fi) Uusia 2-syaani-3-hydroksipropenamidijohdannaisia, menetelmä niiden valmistamiseksi, niiden käyttö lääkkeinä ja niitä sisältävät farmaseuttiset koostumukset
FI971081L (fi) Triatsolopyridatsiinit, menetelmä ja välituotteet niiden valmistamiseksi sekä niiden käyttö lääkeaineina
IT1211135B (it) Composti ad attivita'analgesica e antiinfiammatoria, processo per la loro preparazione e relative composizioni farmaceutiche.
ZA914376B (en) Benzimidazole derivatives,their preparation process,the intermediates obtained,their use as medicaments and the pharmaceutical compositions containing them
IT8219486A0 (it) Nuovi composti ad attivita'antiinfiammatoria, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT1167746B (it) Nitroimidazoli ad attivita' tricomonacida, procedimento per la loro preparazione e relative composizioni farmaceutiche
FI934468A7 (fi) Bentseeniboorihappojohdannaisia, menetelmä niiden valmistamiseksi ja niiden käyttö synteesin välituotteina