TN2009000135A1 - Use of modified cyclosporins - Google Patents

Use of modified cyclosporins

Info

Publication number: TN2009000135A1
Authority: TN; Tunisia
Prior art keywords: cyclosporins; modified; modified cyclosporins; prevention; treatment
Prior art date: 2006-10-12

Application number

TNP2009000135A

Other languages

English (en)

Inventor

Motoyuki Kohjima

Makoto Nakamuta

Original Assignee

Univ Kyushu

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-10-12

Filing date

2009-04-10

Publication date

2010-10-18

2009-04-10 Application filed by Univ Kyushu, Novartis Ag filed Critical Univ Kyushu

2010-10-18 Publication of TN2009000135A1 publication Critical patent/TN2009000135A1/fr

Links

229930182912 cyclosporin Natural products 0.000 title abstract 2
108010036941 Cyclosporins Proteins 0.000 title 1
102000001493 Cyclophilins Human genes 0.000 abstract 1
108010068682 Cyclophilins Proteins 0.000 abstract 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
230000001506 immunosuppresive effect Effects 0.000 abstract 1
208000019423 liver disease Diseases 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Transplantation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

TNP2009000135A 2006-10-12 2009-04-10 Use of modified cyclosporins TN2009000135A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US82922806P	2006-10-12	2006-10-12
PCT/EP2007/060794 WO2008043797A1 (fr)	2006-10-12	2007-10-10	Utilisation de cyclosporines modifiées

Publications (1)

Publication Number	Publication Date
TN2009000135A1 true TN2009000135A1 (en)	2010-10-18

Family

ID=39092021

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TNP2009000135A TN2009000135A1 (en)	2006-10-12	2009-04-10	Use of modified cyclosporins

Country Status (17)

Country	Link
US (1)	US20100130408A1 (fr)
EP (1)	EP2073831A1 (fr)
JP (1)	JP5455632B2 (fr)
KR (1)	KR20090083902A (fr)
CN (1)	CN101557819A (fr)
AU (1)	AU2007306316B2 (fr)
BR (1)	BRPI0719189A2 (fr)
CA (1)	CA2665415A1 (fr)
IL (1)	IL197966A0 (fr)
MA (1)	MA30865B1 (fr)
MX (1)	MX2009003743A (fr)
NO (1)	NO20091694L (fr)
RU (1)	RU2463071C2 (fr)
SG (1)	SG175621A1 (fr)
TN (1)	TN2009000135A1 (fr)
WO (1)	WO2008043797A1 (fr)
ZA (1)	ZA200902300B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20110117055A1 (en)	2009-11-19	2011-05-19	Macdonald James E	Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
CN101843893B (zh) *	2010-05-21	2012-02-01	中国人民解放军第三军医大学	环孢素a在制备抗轮状病毒药物中的应用
CA2801061A1 (fr) *	2010-06-01	2011-12-08	Auspex Pharmaceuticals, Inc.	Inhibiteurs benzoquinolone de vmat2
US9550780B2 (en)	2012-09-18	2017-01-24	Auspex Pharmaceuticals, Inc.	Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
CA2883641C (fr)	2012-09-18	2021-09-14	Auspex Pharmaceuticals, Inc.	Pharmacocinetiques de formulations d'inhibiteurs de benzoquinoline deutere du transporteur 2 de monoamine vesiculaire
CN105873589B (zh)	2013-12-03	2019-11-01	奥斯拜客斯制药有限公司	制造苯并喹啉化合物的方法
CN114767672A (zh)	2015-03-06	2022-07-22	奥斯拜客斯制药有限公司	氘代丁苯那嗪或包含氘代丁苯那嗪的组合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5639724A (en) *	1984-07-24	1997-06-17	Sandoz Ltd.	Cyclosporin galenic forms
US5908621A (en) *	1995-11-02	1999-06-01	Schering Corporation	Polyethylene glycol modified interferon therapy
FR2757521B1 (fr) *	1996-12-24	1999-01-29	Rhone Poulenc Rorer Sa	Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757522B1 (fr) *	1996-12-24	1999-01-29	Rhone Poulenc Rorer Sa	Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
JPH1180026A (ja) *	1997-09-02	1999-03-23	Yoshitomi Pharmaceut Ind Ltd	新規免疫抑制剤、その使用方法およびその同定方法
US20030216303A1 (en) *	1998-03-06	2003-11-20	Michael Ambuhl	Emulsion preconcentrates containing cyclosporin or a macrolide
PT1091975E (pt) *	1998-07-01	2006-05-31	Debiopharm Sa	Nova ciclosporina com um perfil de actividade melhorado
EP1177796B1 (fr) *	1999-04-27	2011-04-27	Mitsubishi Tanabe Pharma Corporation	Médicament pour la prévention ou le traitement des maladies du foie
JPWO2002030464A1 (ja) *	2000-10-11	2004-02-19	江頭健輔	新規肝疾患用薬
US20030213603A1 (en) *	2002-05-14	2003-11-20	Fisher David B.	Dual use extension apparatus for a tool
GB0320638D0 (en) *	2003-09-03	2003-10-01	Novartis Ag	Organic compounds
US7079552B2 (en) *	2003-09-09	2006-07-18	Harris Corporation	Mobile ad hoc network (MANET) with quality-of-service (QoS) protocol hierarchy and related methods
UA88484C2 (ru) *	2004-10-01	2009-10-26	Дебиофарм Са	ПРИМЕНЕНИЕ [D-MeAla]3-[EtVal]4-ЦИКЛОСПОРИНА ДЛЯ ЛЕЧЕНИЯ ИНФЕКЦИИ ГЕПАТИТА С И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, КОТОРАЯ ВКЛЮЧАЕТ [D-MeAla]3-[EtVal]4-ЦИКЛОСПОРИН
JP5139065B2 (ja) *	2004-10-01	2013-02-06	スシネキスインク	Ｃ型肝炎感染の治療及び予防のための３−エーテル及び３−チオエーテル置換シクロスポリン誘導体
CA2587793A1 (fr) *	2004-12-23	2006-07-06	Novartis Ag	Compositions pour le traitement du vhc
US8512690B2 (en) *	2009-04-10	2013-08-20	Novartis Ag	Derivatised proline containing peptide compounds as protease inhibitors

2007
- 2007-10-10 BR BRPI0719189A patent/BRPI0719189A2/pt not_active IP Right Cessation
- 2007-10-10 KR KR1020097009615A patent/KR20090083902A/ko not_active Ceased
- 2007-10-10 CN CNA2007800410447A patent/CN101557819A/zh active Pending
- 2007-10-10 RU RU2009117699/15A patent/RU2463071C2/ru not_active IP Right Cessation
- 2007-10-10 US US12/444,941 patent/US20100130408A1/en not_active Abandoned
- 2007-10-10 JP JP2009531841A patent/JP5455632B2/ja not_active Expired - Fee Related
- 2007-10-10 AU AU2007306316A patent/AU2007306316B2/en not_active Ceased
- 2007-10-10 CA CA002665415A patent/CA2665415A1/fr not_active Abandoned
- 2007-10-10 EP EP07821161A patent/EP2073831A1/fr not_active Withdrawn
- 2007-10-10 WO PCT/EP2007/060794 patent/WO2008043797A1/fr not_active Ceased
- 2007-10-10 SG SG2011074572A patent/SG175621A1/en unknown
- 2007-10-10 MX MX2009003743A patent/MX2009003743A/es active IP Right Grant
2009
- 2009-04-02 ZA ZA200902300A patent/ZA200902300B/xx unknown
- 2009-04-05 IL IL197966A patent/IL197966A0/en unknown
- 2009-04-10 TN TNP2009000135A patent/TN2009000135A1/fr unknown
- 2009-04-28 NO NO20091694A patent/NO20091694L/no not_active Application Discontinuation
- 2009-05-06 MA MA31842A patent/MA30865B1/fr unknown

Also Published As

Publication number	Publication date
BRPI0719189A2 (pt)	2018-08-14
JP5455632B2 (ja)	2014-03-26
NO20091694L (no)	2009-07-10
EP2073831A1 (fr)	2009-07-01
MA30865B1 (fr)	2009-11-02
MX2009003743A (es)	2009-06-18
WO2008043797A1 (fr)	2008-04-17
IL197966A0 (en)	2011-08-01
RU2463071C2 (ru)	2012-10-10
AU2007306316A1 (en)	2008-04-17
SG175621A1 (en)	2011-11-28
CA2665415A1 (fr)	2008-04-17
CN101557819A (zh)	2009-10-14
RU2009117699A (ru)	2010-11-20
AU2007306316B2 (en)	2011-10-27
KR20090083902A (ko)	2009-08-04
US20100130408A1 (en)	2010-05-27
ZA200902300B (en)	2010-10-27
JP2010505912A (ja)	2010-02-25

Publication	Publication Date	Title
TNSN07240A1 (en)	2008-11-21	Compounds for flaviviridae treatment
TNSN06071A1 (en)	2007-10-03	Use of modified cyclosporins for the treatment of hcv disorders
MY158325A (en)	2016-09-30	Multitype peptide compositions and methods for treatment or prevention of human papillpmavirus infection
WO2011048390A3 (fr)	2011-11-03	Agents de ciblage de gadd45 bêta
WO2007001851A3 (fr)	2007-03-22	Préparations et méthodes pour le diagnostic et le traitement d'une tumeur
PL1986669T3 (pl)	2012-09-28	Zastosowanie Bifidobacterium longum do zapobiegania i leczenia zapalenia
MX356129B (es)	2018-05-16	Peptidos y analogos de peptidos protectores de los tejidos para evitar y tratar padecimientos y desordenes asociados con daño de los tejidos.
WO2010034032A3 (fr)	2010-05-20	Procédés pour préparer des compositions de polypeptide purifié
CL2007002261A1 (es)	2008-05-02	Compuestos derivados de imidazo[1,2-b]piridazina, inhibidores de quinasa; composicion farmaceutica; y uso en el tratamiento o prevencion del cancer.
PT1854477T (pt)	2016-11-10	Inibidores peptidicos da calicreína plasmática e sua utilização no tratamento de doenças oftalmológicas
MX2012009748A (es)	2012-12-05	USO DE PEPTIDOS INHIBIDORES DEL FACTOR DE CRECIMIENTO TRANSFORMANTE-BETA1(TGF-ß1) PARA EL TRATAMIENTO DE FIBROSIS Y/U OPACIDAD CORNEAL.
MY160041A (en)	2017-02-15	Compositions and methods for treating parasitic infections
MX2010001779A (es)	2010-07-06	Peptidos para vacunas.
WO2009099677A3 (fr)	2009-12-17	Macrocycles peptidomimétiques thérapeutiques
MX2009003743A (es)	2009-06-18	Uso de ciclosporinas modificadas.
TW200612918A (en)	2006-05-01	Lonidamine analogs
MY147247A (en)	2012-11-14	Organic compounds and their uses
AU313297S (en)	2007-03-12	Cover
MX2008011633A (es)	2008-12-16	Aminoquinolonas como inhibidores de gsk-3.
WO2009099467A3 (fr)	2009-10-22	Compositions de cyclosporine
IL186325A0 (en)	2008-02-09	Tizanidine compositions and methods of treatment using the compositions
TW200716091A (en)	2007-05-01	New therapeutic combinations for the treatment or prevention of psychotic disorders
WO2008078167A3 (fr)	2008-08-21	Peptide de consensus
MX2010005915A (es)	2010-07-01	Derivados de fenil-oxetanilo.
BRPI0509690A (pt)	2007-10-09	nim811 na isquemia cerebral e danos cerebrais e na medula espinhal