MA30865B1 - Utilisation de cyclosporines modifiees - Google Patents

Utilisation de cyclosporines modifiees

Info

Publication number
MA30865B1
MA30865B1 MA31842A MA31842A MA30865B1 MA 30865 B1 MA30865 B1 MA 30865B1 MA 31842 A MA31842 A MA 31842A MA 31842 A MA31842 A MA 31842A MA 30865 B1 MA30865 B1 MA 30865B1
Authority
MA
Morocco
Prior art keywords
cyclosporins
modified
modified cyclosporins
cyclophiline
immunosuppressive
Prior art date
Application number
MA31842A
Other languages
English (en)
Inventor
Motoyuki Kohjima
Makoto Nakamuta
Original Assignee
Univ Kyushu
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kyushu, Novartis Ag filed Critical Univ Kyushu
Publication of MA30865B1 publication Critical patent/MA30865B1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'INVENTION CONCERNE UNE CYCLOSPORINE DE LIAISON À LA CYCLOPHILINE NON IMMUNOSUPPRESSIVE, QUI PRÉSENTE DES PROPRIÉTÉS UTILES DANS LA PRÉVENTION OU LE TRAITEMENT DES MALADIES DU FOIE.
MA31842A 2006-10-12 2009-05-06 Utilisation de cyclosporines modifiees MA30865B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82922806P 2006-10-12 2006-10-12

Publications (1)

Publication Number Publication Date
MA30865B1 true MA30865B1 (fr) 2009-11-02

Family

ID=39092021

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31842A MA30865B1 (fr) 2006-10-12 2009-05-06 Utilisation de cyclosporines modifiees

Country Status (17)

Country Link
US (1) US20100130408A1 (fr)
EP (1) EP2073831A1 (fr)
JP (1) JP5455632B2 (fr)
KR (1) KR20090083902A (fr)
CN (1) CN101557819A (fr)
AU (1) AU2007306316B2 (fr)
BR (1) BRPI0719189A2 (fr)
CA (1) CA2665415A1 (fr)
IL (1) IL197966A0 (fr)
MA (1) MA30865B1 (fr)
MX (1) MX2009003743A (fr)
NO (1) NO20091694L (fr)
RU (1) RU2463071C2 (fr)
SG (1) SG175621A1 (fr)
TN (1) TN2009000135A1 (fr)
WO (1) WO2008043797A1 (fr)
ZA (1) ZA200902300B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011063076A1 (fr) 2009-11-19 2011-05-26 Itherx Pharmaceuticals, Inc. Méthodes de traitement du virus de l'hépatite c avec des composés d'oxo-acétamide
CN101843893B (zh) * 2010-05-21 2012-02-01 中国人民解放军第三军医大学 环孢素a在制备抗轮状病毒药物中的应用
WO2011153157A2 (fr) * 2010-06-01 2011-12-08 Auspex Pharmaceutical, Inc. Inhibiteurs benzoquinolone de vmat2
US9550780B2 (en) 2012-09-18 2017-01-24 Auspex Pharmaceuticals, Inc. Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
EP2897615A4 (fr) 2012-09-18 2016-04-27 Auspex Pharmaceuticals Inc Pharmacocinétiques de formulations d'inhibiteurs de benzoquinoline deutéré du transporteur 2 de monoamine vésiculaire
EP3424504A1 (fr) 2013-12-03 2019-01-09 Auspex Pharmaceuticals, Inc. Procédés de fabrication de composés de benzoquinoline
WO2016144901A1 (fr) 2015-03-06 2016-09-15 Auspex Pharmaceuticals, Inc. Méthodes de traitement de troubles des mouvements involontaires anormaux

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
US5908621A (en) * 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
FR2757521B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757522B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
JPH1180026A (ja) * 1997-09-02 1999-03-23 Yoshitomi Pharmaceut Ind Ltd 新規免疫抑制剤、その使用方法およびその同定方法
US20030216303A1 (en) * 1998-03-06 2003-11-20 Michael Ambuhl Emulsion preconcentrates containing cyclosporin or a macrolide
USRE40987E1 (en) * 1998-07-01 2009-11-17 Debiopharm S.A. Cyclosporin with improved activity profile
AU4144400A (en) * 1999-04-27 2000-11-10 Mitsubishi Pharma Corporation Preventives/remedies for liver diseases
WO2002030464A1 (fr) * 2000-10-11 2002-04-18 Daiichi Pharmaceutical Co., Ltd. Nouveaux medicaments pour maladies du foie
US20030213603A1 (en) * 2002-05-14 2003-11-20 Fisher David B. Dual use extension apparatus for a tool
GB0320638D0 (en) * 2003-09-03 2003-10-01 Novartis Ag Organic compounds
US7079552B2 (en) * 2003-09-09 2006-07-18 Harris Corporation Mobile ad hoc network (MANET) with quality-of-service (QoS) protocol hierarchy and related methods
PT1793844E (pt) * 2004-10-01 2011-03-10 Debiopharm Sa Utilização de [d-meala]3-[etval]4-csa para o tratamento de infecção causada pelo vírus da hepatite c
SI1802650T1 (sl) * 2004-10-01 2012-03-30 Scynexis Inc Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c
US7897565B2 (en) * 2004-12-23 2011-03-01 Novartis Ag Compositions for HCV treatment
US8512690B2 (en) * 2009-04-10 2013-08-20 Novartis Ag Derivatised proline containing peptide compounds as protease inhibitors

Also Published As

Publication number Publication date
AU2007306316A1 (en) 2008-04-17
US20100130408A1 (en) 2010-05-27
IL197966A0 (en) 2011-08-01
AU2007306316B2 (en) 2011-10-27
NO20091694L (no) 2009-07-10
WO2008043797A1 (fr) 2008-04-17
KR20090083902A (ko) 2009-08-04
SG175621A1 (en) 2011-11-28
TN2009000135A1 (en) 2010-10-18
RU2463071C2 (ru) 2012-10-10
CN101557819A (zh) 2009-10-14
JP2010505912A (ja) 2010-02-25
EP2073831A1 (fr) 2009-07-01
JP5455632B2 (ja) 2014-03-26
MX2009003743A (es) 2009-06-18
ZA200902300B (en) 2010-10-27
BRPI0719189A2 (pt) 2018-08-14
CA2665415A1 (fr) 2008-04-17
RU2009117699A (ru) 2010-11-20

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