TR199600779A2 - Imidazo benzodiazepin türevlerinin imal edilmesine mahsus yöntem. - Google Patents

Imidazo benzodiazepin türevlerinin imal edilmesine mahsus yöntem.

Info

Publication number: TR199600779A2
Authority: TR; Turkey
Prior art keywords: production; benzodiazepine derivatives; imidazo; imidazo benzodiazepine; derivatives
Prior art date: 1995-10-10

Application number

TR96/00779A

Other languages

English (en)

Inventor

Karl-Heinz Bender

Manfred Breuninger

Manfred Froom

Siegfried Schmitt

Kurt Steiner

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-10

Filing date

1996-09-30

Publication date

1997-04-22

1996-09-30 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1997-04-22 Publication of TR199600779A2 publication Critical patent/TR199600779A2/tr

Links

KLNFAMGHSZQYHR-UHFFFAOYSA-N imidazo[4,5-i][1,2]benzodiazepine Chemical class C1=CC=NN=C2C3=NC=NC3=CC=C21 KLNFAMGHSZQYHR-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

TR96/00779A 1995-10-10 1996-09-30 Imidazo benzodiazepin türevlerinin imal edilmesine mahsus yöntem. TR199600779A2 (tr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH285495		1995-10-10

Publications (1)

Publication Number	Publication Date
TR199600779A2 true TR199600779A2 (tr)	1997-04-22

Family

ID=4243076

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TR96/00779A TR199600779A2 (tr)	1995-10-10	1996-09-30	Imidazo benzodiazepin türevlerinin imal edilmesine mahsus yöntem.

Country Status (14)

Country	Link
US (1)	US5693795A (tr)
EP (1)	EP0768310B1 (tr)
JP (1)	JP3007050B2 (tr)
CN (1)	CN1060776C (tr)
AR (1)	AR003800A1 (tr)
AT (1)	ATE187727T1 (tr)
BR (1)	BR9605030A (tr)
CA (1)	CA2184802C (tr)
DE (1)	DE59603916D1 (tr)
DK (1)	DK0768310T3 (tr)
ES (1)	ES2141428T3 (tr)
GR (1)	GR3032600T3 (tr)
MX (1)	MX9604687A (tr)
TR (1)	TR199600779A2 (tr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6512114B1 (en) *	1999-06-30	2003-01-28	Abbott Laboratories	Process for the preparation of Midazolam
US6262260B1 (en) *	2000-03-23	2001-07-17	Abbott Laboratories	Process for the preparation of midazolam
JP4298212B2 (ja) *	2002-03-29	2009-07-15	大日本印刷株式会社	塩酸エピナスチン高融点型結晶の製造法
TW200950812A (en) *	2008-02-08	2009-12-16	Colgate Palmolive Co	Effervescent compositions
TWI386176B (zh) *	2008-02-08	2013-02-21	Colgate Palmolive Co	口腔保健牙刷
CA2706516C (en) *	2008-02-08	2014-12-16	Colgate-Palmolive Company	Cleaning compositions and methods
JP2011511798A (ja) *	2008-02-08	2011-04-14	コルゲート・パーモリブ・カンパニー	塩基性アミノ酸および可溶性炭酸塩を含む組成物
CN101938955A (zh)	2008-02-08	2011-01-05	高露洁-棕榄公司	牙线
WO2009100277A2 (en)	2008-02-08	2009-08-13	Colgate-Palmolive Company	Compositions and devices
TWI409084B (zh) *	2008-02-08	2013-09-21	美國棕欖公司	治療口乾症之組成物及方法
BRPI0906452A2 (pt) *	2008-02-08	2015-07-14	Colgate Palmolive Co	Composição, dispositivo, método para produzir ou inibir a formação de cáries dentais, reduzir, reparar ou inibir as leões pré-cárie do esmalte, reduzir ou inibir a desmineralização e promover a remineralização dos dentes, reduzir a hipersensibilidade dos dentes, reduzir ou inibir a gengivite, promover a cura de feridas ou de cortes na boca, reduzir os níveis de bactérias que produzem ácido, aumentar os níveis relativos de bactérias arginolíticas, inibir a formação de composição, dispositivo, método para reduzir ou inibir a formação de cáries dentais, reduzir, reparar ou inibir as leões pré-cárie dp esmalte, reduzir ou inibir a desmineralização e promover a remineralização dos dentes, reduzir a hipersibilidade dos dentes, reduzir ou inibir a gengivite, promover a cura de feridas ou de cortes na boca, reduzir os níveis de bactérias que produzem ácido, aumentar os níveis relativos de bactérias arginolíticas, inibir a formação de biofilme microbiano na cavidade oral, elevar e/ou manter o ph da placa em níveis de pelos menos um ph de 5,5, reduzir o acúmulo de placa, tratar, aliviar ou reduzir a boca seca, limpar os dentes e a cavidade oral, reduzir a erosão, branquear os dentes, imunizar os dentes contra as bactérias cariogênicas, e/ ou promover a saúde sistêmica, incluindo a saúde cardiovascular, e, uso de um aminoácido básico
EP2249794A4 (en) *	2008-02-08	2014-01-08	Colgate Palmolive Co	COMPOSITIONS AND METHODS COMPRISING BASIC AMINO ACID PEPTIDES AND PROTEASES
CN101938970A (zh) *	2008-02-08	2011-01-05	高露洁-棕榄公司	牙齿密封剂
IT1399764B1 (it) *	2010-05-04	2013-05-03	F S I Fabbrica Italiana Sint	Procedimento per la sintesi di 4h-imidazo [1,5-a][1,4]benzodiazepine, in particolare di midazolam.
UA110640C2 (uk)	2011-05-05	2016-01-25	Янссен Фармацевтика Нв	ПРОТИГРИБКОВІ 5,6-ДИГІДРО-4Н-ПІРОЛО[1,2-a][1,4]БЕНЗОДІАЗЕПІНИ ТА 6Н-ПІРОЛО[1,2-a][1,4]БЕНЗОДІАЗЕПІНИ, ЯКІ ЗАМІЩЕНІ ГЕТЕРОЦИКЛІЧНИМИ ПОХІДНИМИ
CN109790170B (zh)	2016-08-16	2022-08-02	Uwm研究基金会有限公司	Gaba(a)受体调节剂和控制哮喘中气道高反应性和炎症的方法
CN113603635B (zh) *	2021-10-08	2021-12-24	湖南速博生物技术有限公司	一种芳香族二元羧酸酯水解脱羧的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4280957A (en) *	1974-09-11	1981-07-28	Hoffmann-La Roche Inc.	Imidazodiazepines and processes therefor
US4307237A (en) *	1974-09-11	1981-12-22	Hoffmann-La Roche Inc.	Imidazoles
DE2609486A1 (de) *	1975-08-07	1977-05-12	Hoffmann La Roche	Imidazo eckige klammer auf 1,5-a eckige klammer zu eckige klammer auf 1,4 eckige klammer zu diazepin-verbindungen und verfahren zu ihrer herstellung

1996
- 1996-09-04 CA CA002184802A patent/CA2184802C/en not_active Expired - Fee Related
- 1996-09-30 TR TR96/00779A patent/TR199600779A2/tr unknown
- 1996-10-02 US US08/724,801 patent/US5693795A/en not_active Expired - Lifetime
- 1996-10-03 JP JP8262205A patent/JP3007050B2/ja not_active Expired - Fee Related
- 1996-10-04 DK DK96115949T patent/DK0768310T3/da active
- 1996-10-04 AT AT96115949T patent/ATE187727T1/de active
- 1996-10-04 AR ARP960104609A patent/AR003800A1/es active IP Right Grant
- 1996-10-04 DE DE59603916T patent/DE59603916D1/de not_active Expired - Lifetime
- 1996-10-04 ES ES96115949T patent/ES2141428T3/es not_active Expired - Lifetime
- 1996-10-04 EP EP96115949A patent/EP0768310B1/de not_active Expired - Lifetime
- 1996-10-08 CN CN96113070A patent/CN1060776C/zh not_active Expired - Fee Related
- 1996-10-09 MX MX9604687A patent/MX9604687A/es unknown
- 1996-10-09 BR BR9605030A patent/BR9605030A/pt not_active Application Discontinuation
2000
- 2000-02-09 GR GR20000400298T patent/GR3032600T3/el unknown

Also Published As

Publication number	Publication date
JPH09110871A (ja)	1997-04-28
EP0768310A1 (de)	1997-04-16
CN1150152A (zh)	1997-05-21
DE59603916D1 (de)	2000-01-20
CA2184802C (en)	2007-07-31
BR9605030A (pt)	1998-06-30
CA2184802A1 (en)	1997-04-11
MX9604687A (es)	1997-04-30
DK0768310T3 (da)	2000-04-17
US5693795A (en)	1997-12-02
GR3032600T3 (en)	2000-05-31
AR003800A1 (es)	1998-09-09
JP3007050B2 (ja)	2000-02-07
ATE187727T1 (de)	2000-01-15
ES2141428T3 (es)	2000-03-16
CN1060776C (zh)	2001-01-17
EP0768310B1 (de)	1999-12-15

Similar Documents

Publication	Publication Date	Title
IS4148A (is)	1994-10-16	Hliðstæð aðferð til framleiðslu á 1,5 Benzodiazepine afleiðum
IS4570A (is)	1997-09-25	Imidazó[1,2-a]pýridín afleiður
TR199600792A2 (tr)	1997-05-21	Dihaloazolopirimidinlerin hazirlanmasina yönelik proses.
TR199600779A2 (tr)	1997-04-22	Imidazo benzodiazepin türevlerinin imal edilmesine mahsus yöntem.
FI102474B1 (fi)	1998-12-15	Menetelmä moniarvoisten alkoholien valmistamiseksi
IS3970A (is)	1993-07-22	Hliðstæð aðferð til framleiðslu á 1,5-benzódíazepín afleiðum
NO961483L (no)	1996-10-15	Fremgangsmåte for behandling av oljeholdig formasjon
NO961006L (no)	1996-09-16	Fosfonomononukleinsyrer, fremgangsmåter for fremstilling derav og anvendelse av forbindelsene
NO983766D0 (no)	1998-08-18	FremgangsmÕte til fremstilling av N-acetyl-D-glukosamin
FI973281L (fi)	1997-08-08	Menetelmä tiettyjen atsasykloheksapeptidien valmistamiseksi
FI956154A0 (fi)	1995-12-20	Telemetrisk maetning av et mobiltelefonnaet
NO981800D0 (no)	1998-04-22	FremgangsmÕte for fremstilling av 1,1,1,3,3-pentafluorpentan
FI960278A0 (fi)	1996-01-19	Anataasititaanidioksidin valmistusmenetelmä
TR199800608A3 (tr)	1998-10-21	Propanolamin türevleri, bunlarin üretim usulü.
IS4190A (is)	1995-01-21	Hliðstæð aðferð til framleiðslu á 1,5 bensódíasepín afleiðum
BR9612246A (pt)	1999-07-13	Derivados octaidro-pirrol(1,2-a)pirazinha 2,7-substituidos
NO982237L (no)	1998-07-10	FremgangsmÕte for fremstilling av fenylimidazolidinderivater
AU3207297A (en)	1998-01-21	Process for the production of 8-chloro-6-(2-fluorophenyl)-1-methyl-4h-imidazo{1,5-a}benzod iazepine
TR199800403A3 (tr)	1998-09-21	a-Bromo-laktam türevlerinin hazirlanmasi için yöntem.
IT1305273B1 (it)	2001-04-19	Impianto e procedimento perfezionati per la produzione dipreforme multistrato.
NO996432L (no)	2000-02-09	Fremgangsmåte for fremstilling av 4-substituert-1H-indol-3- glykosamider
TR199800068A3 (tr)	1998-08-21	Benzofenon türevlerinin hazirlanmasina yönelik metodlar.
NO985824D0 (no)	1998-12-11	Forbedret fremgangsmÕte for fremstilling av kalium-clavulanat
PL324928A1 (en)	1998-06-22	Derivatives of pyrimidin-4-one, their application, intermediate compounds for their production and methods of obtaining such intermediate compounds
NO973835D0 (no)	1997-08-20	Fremgangsmåte for fremstilling av lorakarbefmonohydrat