TR199801839T2 - - Google Patents

Info

Publication number
TR199801839T2
TR199801839T2 TR1998/01839T TR9801839T TR199801839T2 TR 199801839 T2 TR199801839 T2 TR 199801839T2 TR 1998/01839 T TR1998/01839 T TR 1998/01839T TR 9801839 T TR9801839 T TR 9801839T TR 199801839 T2 TR199801839 T2 TR 199801839T2
Authority
TR
Turkey
Prior art keywords
group
alkyl
alkoxy
hydrogen
halogen atom
Prior art date
Application number
TR1998/01839T
Other languages
English (en)
Inventor
Sevrin Mireille
Marabout Benoit
George Pascal
Merly Jean-Pierre
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of TR199801839T2 publication Critical patent/TR199801839T2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Asagidaki genel formüle (I) karsilik gelen bilesikler olup burada; R1, R2 ve R3'den her biri bir hidrojen veya halojen atomunu veya bir hidroksil, alkil veya alkoksi grubunu simgelemekte, R4 bir hidrojen veya halojen atomunu veya bir alkil, 2-metoksietoksi, alkoksi, sikloalkilmetoksi veya fenilmetoksi grubunu simgelemekte, veya alternatif olarak R3 ve R4 birlikte bir metilendioksi grubunu olusturmakta, Z oksijen veya iki hidrojen atomunu simgelemekte ve R;Z oksijeni veya alternatif olarak istege bagli bir sekilde bir veya daha fazla halojen atomuyla veya alkil, alkoksi veya amino gruplariyla yer degistirilmis bir fenil grubunu simgelediginde bir etoksi grubunu simgelemektedir. Tedavi maksatli uygulamadir.
TR1998/01839T 1996-04-12 1997-04-10 TR199801839T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9604565A FR2747386B1 (fr) 1996-04-12 1996-04-12 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
TR199801839T2 true TR199801839T2 (tr) 1998-12-21

Family

ID=9491132

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/01839T TR199801839T2 (tr) 1996-04-12 1997-04-10

Country Status (22)

Country Link
EP (1) EP0892800A1 (tr)
JP (1) JP2000512620A (tr)
KR (1) KR20000005392A (tr)
CN (1) CN1216046A (tr)
AR (1) AR008587A1 (tr)
AU (1) AU2640997A (tr)
BG (1) BG102779A (tr)
BR (1) BR9708654A (tr)
CA (1) CA2251335A1 (tr)
CO (1) CO4900067A1 (tr)
CZ (1) CZ326898A3 (tr)
EE (1) EE9800396A (tr)
FR (1) FR2747386B1 (tr)
IL (1) IL126473A0 (tr)
NO (1) NO984736L (tr)
NZ (1) NZ332257A (tr)
PL (1) PL329243A1 (tr)
SK (1) SK141598A3 (tr)
TR (1) TR199801839T2 (tr)
TW (1) TW407158B (tr)
WO (1) WO1997038998A1 (tr)
ZA (1) ZA973124B (tr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102131790A (zh) * 2008-06-27 2011-07-20 H.隆德贝克有限公司 新型苯酚型和儿茶酚型胺及其前药
EP3495363B1 (en) 2016-07-28 2023-08-23 Shionogi & Co., Ltd Nitrogen-containing condensed ring compounds having dopamine d3 receptor antagonistic effect
EP3744721B1 (en) 2018-01-26 2025-07-02 Shionogi & Co., Ltd. Condensed ring compounds having dopamine d3 receptor antagonistic effect

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU895334D0 (en) * 1986-07-30 1990-01-28 Sandoz Ag Process for the preparation of nasal pharmaceutical compositions
EP0306375A1 (fr) * 1987-08-07 1989-03-08 Synthelabo Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique
IL89156A (en) * 1988-07-12 1993-05-13 Synthelabo Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics
FR2661178B1 (fr) * 1990-04-24 1993-03-12 Synthelabo Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
EE9800396A (et) 1999-06-15
EP0892800A1 (fr) 1999-01-27
CN1216046A (zh) 1999-05-05
AR008587A1 (es) 2000-02-09
IL126473A0 (en) 1999-08-17
KR20000005392A (ko) 2000-01-25
AU2640997A (en) 1997-11-07
PL329243A1 (en) 1999-03-15
TW407158B (en) 2000-10-01
BR9708654A (pt) 1999-08-03
BG102779A (en) 1999-09-30
JP2000512620A (ja) 2000-09-26
NZ332257A (en) 1999-03-29
NO984736L (no) 1998-11-23
FR2747386B1 (fr) 1998-05-15
WO1997038998A1 (fr) 1997-10-23
ZA973124B (en) 1997-11-05
SK141598A3 (en) 1999-03-12
CO4900067A1 (es) 2000-03-27
NO984736D0 (no) 1998-10-09
CA2251335A1 (en) 1997-10-23
CZ326898A3 (cs) 1999-01-13
FR2747386A1 (fr) 1997-10-17

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