TR199802146T2 - Saf azetidin-2-karboksilik asitin üretilmesi için gelistirilmis yöntem - Google Patents
Saf azetidin-2-karboksilik asitin üretilmesi için gelistirilmis yöntemInfo
- Publication number
- TR199802146T2 TR199802146T2 TR1998/02146T TR9802146T TR199802146T2 TR 199802146 T2 TR199802146 T2 TR 199802146T2 TR 1998/02146 T TR1998/02146 T TR 1998/02146T TR 9802146 T TR9802146 T TR 9802146T TR 199802146 T2 TR199802146 T2 TR 199802146T2
- Authority
- TR
- Turkey
- Prior art keywords
- production
- carboxylic acid
- improved method
- pure
- azeoh
- Prior art date
Links
- IADUEWIQBXOCDZ-VKHMYHEASA-N Azetidine-2-carboxylic acid Natural products OC(=O)[C@@H]1CCN1 IADUEWIQBXOCDZ-VKHMYHEASA-N 0.000 title abstract 2
- IADUEWIQBXOCDZ-UHFFFAOYSA-N azetidine-2-carboxylic acid Chemical compound OC(=O)C1CCN1 IADUEWIQBXOCDZ-UHFFFAOYSA-N 0.000 title 2
- -1 AzeOH tartrate salt Chemical class 0.000 abstract 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000002906 tartaric acid Nutrition 0.000 abstract 1
- 239000011975 tartaric acid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Bulus, AzeOH, optik açidan aktif tartarik asit, bir organik asit ve aldehit solüsyonundan diastereomik açidan saf bir AzeOH tartrat tuzunun seçici kristalizasyonunu içeren ve bir serbest amino asidin açiga çikmasiyla takip edilen, enantiyomerik açidan saf bir AZeOH üretimi için bir yöntemle ilgilidir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9601600A SE9601600D0 (sv) | 1996-04-26 | 1996-04-26 | Improved process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199802146T2 true TR199802146T2 (tr) | 1999-01-18 |
Family
ID=20402360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1998/02146T TR199802146T2 (tr) | 1996-04-26 | 1997-04-22 | Saf azetidin-2-karboksilik asitin üretilmesi için gelistirilmis yöntem |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US6143903A (tr) |
| EP (1) | EP0906255B1 (tr) |
| JP (2) | JP2000509068A (tr) |
| KR (1) | KR100447072B1 (tr) |
| CN (1) | CN1071292C (tr) |
| AR (1) | AR006639A1 (tr) |
| AT (1) | ATE200889T1 (tr) |
| AU (1) | AU713519B2 (tr) |
| BR (1) | BR9708872A (tr) |
| CA (1) | CA2253711C (tr) |
| CZ (1) | CZ339998A3 (tr) |
| DE (1) | DE69704708T2 (tr) |
| DK (1) | DK0906255T3 (tr) |
| EE (1) | EE9800365A (tr) |
| EG (1) | EG20975A (tr) |
| ES (1) | ES2158557T3 (tr) |
| GR (1) | GR3036303T3 (tr) |
| HU (1) | HUP9901665A3 (tr) |
| ID (1) | ID16840A (tr) |
| IL (1) | IL126717A (tr) |
| IN (1) | IN186439B (tr) |
| IS (1) | IS4860A (tr) |
| MY (1) | MY132450A (tr) |
| NO (1) | NO310404B1 (tr) |
| NZ (1) | NZ332155A (tr) |
| PL (1) | PL329685A1 (tr) |
| PT (1) | PT906255E (tr) |
| SE (1) | SE9601600D0 (tr) |
| SK (1) | SK140898A3 (tr) |
| TR (1) | TR199802146T2 (tr) |
| WO (1) | WO1997041084A1 (tr) |
| ZA (1) | ZA973156B (tr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69834276T2 (de) * | 1997-01-24 | 2007-04-12 | Sumitomo Chemical Co. Ltd. | Verfahren zur Verbesserung der optischen Reinheit von Azetidin-2-carbonsäure |
| SE9802939D0 (sv) | 1998-09-01 | 1998-09-01 | Astra Ab | New process |
| SE9901712D0 (sv) * | 1999-05-11 | 1999-05-11 | Astra Ab | New process |
| WO2005103005A1 (ja) * | 2004-04-26 | 2005-11-03 | Astellas Pharma Inc. | β-ピリジルアラニンの光学活性体の選択的製造方法 |
| EP2334620B1 (en) * | 2008-09-05 | 2018-09-05 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Process for enantioseparation of chiral systems with compound formation using two subsequent crystallization steps |
| JP2013241338A (ja) * | 2010-09-09 | 2013-12-05 | Mitsubishi Gas Chemical Co Inc | 光学活性2−アミノ酪酸の製造方法 |
| JP2013241339A (ja) * | 2010-09-09 | 2013-12-05 | Mitsubishi Gas Chemical Co Inc | 光学活性アミノ酸の製造方法 |
| CN103204783B (zh) * | 2013-04-18 | 2015-09-02 | 张家港市华昌药业有限公司 | 一种d-赖氨酸盐酸盐的制备方法 |
| WO2016021711A1 (ja) * | 2014-08-07 | 2016-02-11 | 株式会社エーピーアイ コーポレーション | アミノ酸誘導体の製造方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE795874A (fr) * | 1972-02-25 | 1973-08-23 | Glaxo Lab Ltd | Procede de preparation d'esters optiquement actifs d'alpha-amino-acides |
| JPS5139219B2 (tr) * | 1972-06-08 | 1976-10-26 | ||
| US4072698A (en) * | 1976-12-02 | 1978-02-07 | The Upjohn Company | Resolution of aminonitriles |
| JPS56104866A (en) * | 1980-01-24 | 1981-08-20 | Mitsubishi Chem Ind Ltd | Production of (2r,4r)-4-alkyl-2-piperidinecarboxylic acid or its l-tartarate salt |
| DE3303112A1 (de) * | 1983-01-31 | 1984-08-09 | Hoechst Ag, 6230 Frankfurt | Verfahren zur racemattrennung optisch aktiver bicyclischer imino-(alpha)-carbonsaeuren |
| US4923983A (en) * | 1989-07-31 | 1990-05-08 | Eli Lilly And Company | Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-one |
| EP0499376A1 (en) * | 1991-01-31 | 1992-08-19 | Hoechst Celanese Corporation | Precipitation-induced asymmetric transformation of chiral alpha-amino acids and salts thereof |
| GB9420246D0 (en) * | 1994-10-07 | 1994-11-23 | Chiroscience Ltd | Asymmetric crystallisation |
| IN187238B (tr) * | 1995-06-30 | 2002-03-09 | Astra Ab | |
| EP0827954B1 (en) * | 1996-09-06 | 2003-06-04 | Sumitomo Chemical Company Limited | Process for producing optically active azetidine-2-carboxylic acid |
-
1996
- 1996-04-26 SE SE9601600A patent/SE9601600D0/xx unknown
-
1997
- 1997-04-14 ZA ZA9703156A patent/ZA973156B/xx unknown
- 1997-04-14 AR ARP970101487A patent/AR006639A1/es unknown
- 1997-04-22 JP JP9538797A patent/JP2000509068A/ja active Pending
- 1997-04-22 AU AU27194/97A patent/AU713519B2/en not_active Ceased
- 1997-04-22 TR TR1998/02146T patent/TR199802146T2/tr unknown
- 1997-04-22 AT AT97921046T patent/ATE200889T1/de not_active IP Right Cessation
- 1997-04-22 ES ES97921046T patent/ES2158557T3/es not_active Expired - Lifetime
- 1997-04-22 HU HU9901665A patent/HUP9901665A3/hu unknown
- 1997-04-22 PT PT97921046T patent/PT906255E/pt unknown
- 1997-04-22 BR BR9708872A patent/BR9708872A/pt not_active Application Discontinuation
- 1997-04-22 PL PL97329685A patent/PL329685A1/xx unknown
- 1997-04-22 CA CA002253711A patent/CA2253711C/en not_active Expired - Fee Related
- 1997-04-22 US US08/913,016 patent/US6143903A/en not_active Expired - Fee Related
- 1997-04-22 WO PCT/SE1997/000675 patent/WO1997041084A1/en not_active Ceased
- 1997-04-22 EP EP97921046A patent/EP0906255B1/en not_active Expired - Lifetime
- 1997-04-22 IL IL12671797A patent/IL126717A/en not_active IP Right Cessation
- 1997-04-22 CN CN97194111A patent/CN1071292C/zh not_active Expired - Fee Related
- 1997-04-22 DK DK97921046T patent/DK0906255T3/da active
- 1997-04-22 NZ NZ332155A patent/NZ332155A/xx not_active IP Right Cessation
- 1997-04-22 SK SK1408-98A patent/SK140898A3/sk unknown
- 1997-04-22 DE DE69704708T patent/DE69704708T2/de not_active Expired - Lifetime
- 1997-04-22 KR KR10-1998-0708557A patent/KR100447072B1/ko not_active Expired - Fee Related
- 1997-04-22 EE EE9800365A patent/EE9800365A/xx unknown
- 1997-04-22 CZ CZ983399A patent/CZ339998A3/cs unknown
- 1997-04-23 EG EG32897A patent/EG20975A/xx active
- 1997-04-23 MY MYPI97001747A patent/MY132450A/en unknown
- 1997-04-24 IN IN1060DE1997 patent/IN186439B/en unknown
- 1997-04-25 ID IDP971396A patent/ID16840A/id unknown
-
1998
- 1998-10-06 IS IS4860A patent/IS4860A/is unknown
- 1998-10-07 NO NO19984681A patent/NO310404B1/no not_active IP Right Cessation
-
2001
- 2001-07-31 GR GR20010401153T patent/GR3036303T3/el unknown
-
2008
- 2008-11-13 JP JP2008290436A patent/JP2009120611A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ506329A (en) | Inhibitors of phospholipase enzymes | |
| TR200002059T2 (tr) | Devamlı salınan bileşim, üretim yöntemi ve kullanımı. | |
| BRPI0009721B8 (pt) | Inibidores de tirosina quinase de proteína cíclica | |
| TR200201638T2 (tr) | Yeni imidazo[1,3,5]triazinonlar ve kullanımları | |
| DE69711632D1 (de) | Methode zur dissoziation von biotin komplexen | |
| ATE320457T1 (de) | Polyurethanlösungen mit alkoxysilanstruktureinheiten | |
| TR200003206T2 (tr) | İndol türevleri ve patolojik hücre çoğalmasının neden olduğu habis hastalıklar ve diğer hastalıkların tedavisinde kullanımları. | |
| ATE206038T1 (de) | Orale zusammensetzung enthaltend stabilisierte zinn komponente | |
| EA200100731A1 (ru) | Фенилфенантридины с ингибирующей фдэ-4 активностью | |
| ATE430589T1 (de) | Wasserbehandlung zur kontrolle von biobewuchs mittels stabilisierter bromlösungen | |
| BRPI0414598A (pt) | indóis substituìdos | |
| DE60111362D1 (de) | Stabilisierte ascorbinsäure-lösungen | |
| ES2119812T3 (es) | Catalasa, su produccion y uso. | |
| TR200100109T2 (tr) | Optikçe aktif oktanoik asit türevleri hazırlamak için yeni ara bileşikler ve yöntemler | |
| DE60025905D1 (de) | In vitro methode zur synchronisation von oozytenreifung | |
| ATE437642T1 (de) | Prodrugs von imidazol-derivaten, zur verwendung als protonenpumpen-hemmer zur behandlung von z.b. peptischen magengeschwüren | |
| PA8563601A1 (es) | Acidos-3-(imidazolil)-2- alcoxipropanoicos | |
| TR199700261A2 (tr) | Yeni Pirimido (1,2-a) indoller. | |
| ATE295352T1 (de) | Phenanthridine-n-oxide mit pde-iv hemmender wirkung | |
| PT1067966E (pt) | Composicao oftalmica compreendendo um bloqueador beta | |
| TR200101366T2 (tr) | Farmasötik kompozisyonların muhtevasında bulunan bazı substitüte kaprolaktamlar ve tümör tedavisinde kullanımları. | |
| TR199701742T1 (tr) | Enantiyomerik olarak saf azetidin-2-karboksilik asit üretim prosesi. | |
| DE50107209D1 (de) | Verfahren zur herstellung von 5-aminosalicylsäure | |
| NO960826L (no) | Anvendelse av enzymer fra krill i forstoffer | |
| JP2004532111A5 (tr) |