TR200000480T2 - HPV' ye karşı aşı. - Google Patents
HPV' ye karşı aşı.Info
- Publication number
- TR200000480T2 TR200000480T2 TR2000/00480T TR200000480T TR200000480T2 TR 200000480 T2 TR200000480 T2 TR 200000480T2 TR 2000/00480 T TR2000/00480 T TR 2000/00480T TR 200000480 T TR200000480 T TR 200000480T TR 200000480 T2 TR200000480 T2 TR 200000480T2
- Authority
- TR
- Turkey
- Prior art keywords
- hpv
- vaccine against
- against hpv
- boiling
- rebel
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title 1
- 241000701806 Human papillomavirus Species 0.000 abstract 4
- 238000009835 boiling Methods 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
Mevcut bulus, HPV antijenine T yardimci epitoplarini temin eden immünolojik bir kaynasma ortagina bagli olan, insan papillom virüsü (HPV) kaynasma proteinlerini temin eder. HPV ile indüklenmis lezyonlarin tedavisnde ve profilaksisinde faydali olan asi formülasyonlari temin edilir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9717953.5A GB9717953D0 (en) | 1997-08-22 | 1997-08-22 | Vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200000480T2 true TR200000480T2 (tr) | 2000-07-21 |
Family
ID=10817971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/00480T TR200000480T2 (tr) | 1997-08-22 | 1998-08-17 | HPV' ye karşı aşı. |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US6342224B1 (tr) |
| EP (1) | EP1007551B1 (tr) |
| JP (1) | JP2001513986A (tr) |
| KR (1) | KR20010023193A (tr) |
| CN (1) | CN1276833A (tr) |
| AT (1) | ATE267211T1 (tr) |
| AU (1) | AU732946B2 (tr) |
| BR (1) | BR9812139A (tr) |
| CA (1) | CA2301920C (tr) |
| CO (1) | CO4810234A1 (tr) |
| DE (1) | DE69824013T2 (tr) |
| ES (1) | ES2221198T3 (tr) |
| GB (1) | GB9717953D0 (tr) |
| HU (1) | HUP0004327A3 (tr) |
| IL (1) | IL134392A0 (tr) |
| MA (1) | MA24638A1 (tr) |
| NO (1) | NO20000850L (tr) |
| NZ (1) | NZ502632A (tr) |
| PL (1) | PL339009A1 (tr) |
| TR (1) | TR200000480T2 (tr) |
| UY (1) | UY25146A1 (tr) |
| WO (1) | WO1999010375A2 (tr) |
| ZA (1) | ZA987591B (tr) |
Families Citing this family (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
| DE69836092T2 (de) * | 1997-10-24 | 2007-05-10 | Invitrogen Corp., Carlsbad | Rekombinatorisches klonieren unter verwendung von nukleinsaüren mit rekombinationsstellen |
| GB9820525D0 (en) * | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| KR100731820B1 (ko) | 1998-10-05 | 2007-06-25 | 파멕사 에이/에스 | 치료적 백신화를 위한 새로운 방법 |
| SI1117421T1 (en) * | 1998-10-05 | 2004-12-31 | Pharamexa A/S | Methods for therapeutic vaccination |
| ES2284287T3 (es) | 1998-10-16 | 2007-11-01 | Glaxosmithkline Biologicals S.A. | Sistemas adyuvantes y vacunas. |
| ID30407A (id) * | 1999-05-13 | 2001-11-29 | American Cyanamid Co | Formulasi-formulasi kombinasi bahan penambah |
| GB9921146D0 (en) | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
| GB0000891D0 (en) | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
| US7015033B1 (en) * | 2000-05-25 | 2006-03-21 | Aventis Pasteur Limited | Co-expression of recombination proteins |
| US20030104570A1 (en) * | 2000-06-26 | 2003-06-05 | Cabezon Silva Teresa Elisa Virginia | Triple fusion proteins comprising ubiquitin fused between thioredoxin and a polypeptide of interest |
| US7198924B2 (en) | 2000-12-11 | 2007-04-03 | Invitrogen Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites |
| DE60126737T2 (de) | 2001-03-23 | 2007-11-08 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Modifizierte HPV E6- und E7-Gene und -Proteine als Impfstoff |
| WO2003039595A2 (en) * | 2001-11-07 | 2003-05-15 | Inex Pharmaceuticals Corporation | Mucosal adjuvants comprising an oligonucleotide and a cationic lipid |
| US6861410B1 (en) * | 2002-03-21 | 2005-03-01 | Chiron Corporation | Immunological adjuvant compositions |
| FR2839072A1 (fr) * | 2002-04-24 | 2003-10-31 | Neovacs | Produit d'expression d'un adn codant une proteine e7 mutee de hpv-16, composition immunogene contenant ledit produit d'expression et son procede de preparation |
| FR2839080B1 (fr) * | 2003-04-03 | 2007-09-28 | Neovacs | Procede de preparation d'un produit d'expression d'un adn codant une proteine e7 mutee de hpv-16, par des cellules de la levure pichia pastoris |
| US20040009944A1 (en) * | 2002-05-10 | 2004-01-15 | Inex Pharmaceuticals Corporation | Methylated immunostimulatory oligonucleotides and methods of using the same |
| US20040013649A1 (en) * | 2002-05-10 | 2004-01-22 | Inex Pharmaceuticals Corporation | Cancer vaccines and methods of using the same |
| US20040219516A1 (en) * | 2002-07-18 | 2004-11-04 | Invitrogen Corporation | Viral vectors containing recombination sites |
| CN1674933B (zh) | 2002-08-02 | 2012-09-26 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗组合物 |
| CA2496409A1 (en) * | 2002-08-30 | 2004-03-11 | Glaxo Group Limited | Immunogenic composition comprising an il-13 element and t cell epitopes, and its therapeutic use |
| CA2499837C (en) * | 2002-10-03 | 2013-12-03 | Wyeth Holdings Corporation | Human papillomavirus polypeptides and immunogenic compositions |
| CA2503871C (en) | 2002-11-01 | 2012-12-11 | Glaxosmithkline Biologicals S.A. | An immunogenic composition for generating an immune response against polio virus |
| CN100443116C (zh) * | 2002-11-07 | 2008-12-17 | 新纳几美国公司 | 治疗或预防肺炎球菌感染的组合物及其用途 |
| RU2356943C2 (ru) * | 2003-03-24 | 2009-05-27 | Мерк Энд Ко., Инк. | Молекула нуклеиновой кислоты, кодирующая hpv31 l1, экспрессирующий вектор, клетка-хозяин, вирусоподобная частица и способ ее получения, вакцина, фармацевтическая композиция и способы с их использованием |
| CZ297389B6 (cs) * | 2003-07-03 | 2006-11-15 | Ústav Molekulární Biologie Rostlin Av Cr | Fúzní protein pro vakcinaci proti lidskému papillomaviru a zpusob jeho produkce |
| AU2004277342B2 (en) | 2003-10-02 | 2010-12-16 | Glaxosmithkline Biologicals S.A. | Pertussis antigens and use thereof in vaccination |
| DE602004027538D1 (de) * | 2003-12-01 | 2010-07-15 | Life Technologies Corp | Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon |
| EP1732598A4 (en) * | 2003-12-31 | 2009-08-26 | Pharmexa Inc | TRIGGERING CELLULAR IMMUNE RESPONSES TO THE HUMAN PAPILLOVIRUS USING PEPTIDE AND NUCLEIC ACID COMPOSITIONS |
| MXPA06012528A (es) | 2004-04-28 | 2007-08-02 | Headwaters Heavy Oil Llc | Metodos y sistemas de hidroprocesamiento de lecho ebullente y metodos para mejorar un sistema de lecho ebullente existente. |
| US10941353B2 (en) * | 2004-04-28 | 2021-03-09 | Hydrocarbon Technology & Innovation, Llc | Methods and mixing systems for introducing catalyst precursor into heavy oil feedstock |
| US7517446B2 (en) * | 2004-04-28 | 2009-04-14 | Headwaters Heavy Oil, Llc | Fixed bed hydroprocessing methods and systems and methods for upgrading an existing fixed bed system |
| GB0427131D0 (en) * | 2004-12-10 | 2005-01-12 | Glaxosmithkline Biolog Sa | Novel combination |
| GB0505996D0 (en) | 2005-03-23 | 2005-04-27 | Glaxosmithkline Biolog Sa | Fermentation process |
| HUE045482T2 (hu) | 2005-06-27 | 2019-12-30 | Glaxosmithkline Biologicals Sa | Immunogén készítmény |
| US7732166B2 (en) * | 2005-11-15 | 2010-06-08 | Oncohealth Corporation | Detection method for human pappilomavirus (HPV) and its application in cervical cancer |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| KR102511874B1 (ko) | 2006-07-28 | 2023-03-20 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 개선된 백신 및 이의 사용 방법 |
| TW200821026A (en) * | 2006-09-08 | 2008-05-16 | Wyeth Corp | Arginine wash in protein purification using affinity chromatography |
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| EP2433648A3 (en) | 2006-10-12 | 2012-04-04 | GlaxoSmithKline Biologicals S.A. | Vaccine comprising an oil in water emulsion adjuvant |
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| TWI376385B (en) | 2007-12-07 | 2012-11-11 | Nat Health Research Institutes | Production of lipidated proteins in e. coli |
| US8466259B2 (en) | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
| US8142645B2 (en) * | 2008-01-03 | 2012-03-27 | Headwaters Technology Innovation, Llc | Process for increasing the mono-aromatic content of polynuclear-aromatic-containing feedstocks |
| BRPI0922561A2 (pt) | 2008-12-09 | 2020-08-11 | Pfizer Vaccines Llc | vacina de peptídeo de ch3 da ige. |
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| MX2022013063A (es) | 2020-04-24 | 2022-12-08 | Genexine Inc | Metodo para tratamiento del cancer cervicouterino. |
| US12497569B2 (en) | 2022-05-26 | 2025-12-16 | Hydrocarbon Technology & Innovation, Llc | Method and system for mixing catalyst precursor into heavy oil using a high boiling hydrocarbon diluent |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2586428B1 (fr) | 1985-08-26 | 1988-11-25 | Pasteur Institut | Polypeptides et anticorps, caracteristiques du papillomavirus et leurs applications au diagnostic in vitro, a la prevention et/ou la lutte contre des infections a papillomavirus |
| DE3907721A1 (de) | 1989-03-10 | 1990-09-20 | Behringwerke Ag | Immunogene regionen auf dem e7-protein des humanen papillomvierus typ 16 |
| DE4015044A1 (de) | 1990-05-10 | 1991-11-14 | Behringwerke Ag | Seroreaktive epitope auf proteinen des menschlichen papillomavirus (hpv) 18 |
| AU8762991A (en) * | 1990-09-26 | 1992-04-15 | Bristol-Myers Squibb Company | Human papilloma viral protein expression for use in vaccine compositions |
| IL105554A (en) | 1992-05-05 | 1999-08-17 | Univ Leiden | Peptides of human papillomavirus for use in preparations elicit a human T cell response |
| US5869445A (en) * | 1993-03-17 | 1999-02-09 | University Of Washington | Methods for eliciting or enhancing reactivity to HER-2/neu protein |
| DE4441197C1 (de) * | 1994-11-18 | 1996-03-28 | Deutsches Krebsforsch | Expressionsplasmide für Hefe |
| AUPN015794A0 (en) * | 1994-12-20 | 1995-01-19 | Csl Limited | Variants of human papilloma virus antigens |
| AU4727296A (en) * | 1995-02-24 | 1996-09-11 | Cantab Pharmaceuticals Research Limited | Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation |
| US5843752A (en) * | 1995-05-12 | 1998-12-01 | Schering Corporation | Soluble active hepatitis C virus protease |
| US6224870B1 (en) * | 1997-01-24 | 2001-05-01 | Genitrix, Ltd. | Vaccine compositions and methods of modulating immune responses |
| US5958750A (en) * | 1996-07-03 | 1999-09-28 | Inctye Pharmaceuticals, Inc. | Human hyaluronidase |
-
1997
- 1997-08-22 GB GBGB9717953.5A patent/GB9717953D0/en active Pending
-
1998
- 1998-08-17 TR TR2000/00480T patent/TR200000480T2/tr unknown
- 1998-08-17 NZ NZ502632A patent/NZ502632A/en unknown
- 1998-08-17 WO PCT/EP1998/005285 patent/WO1999010375A2/en not_active Ceased
- 1998-08-17 AU AU92639/98A patent/AU732946B2/en not_active Ceased
- 1998-08-17 IL IL13439298A patent/IL134392A0/xx unknown
- 1998-08-17 KR KR1020007001821A patent/KR20010023193A/ko not_active Withdrawn
- 1998-08-17 JP JP2000507701A patent/JP2001513986A/ja active Pending
- 1998-08-17 EP EP98945269A patent/EP1007551B1/en not_active Expired - Lifetime
- 1998-08-17 PL PL98339009A patent/PL339009A1/xx not_active Application Discontinuation
- 1998-08-17 ES ES98945269T patent/ES2221198T3/es not_active Expired - Lifetime
- 1998-08-17 US US09/485,885 patent/US6342224B1/en not_active Expired - Lifetime
- 1998-08-17 DE DE69824013T patent/DE69824013T2/de not_active Expired - Lifetime
- 1998-08-17 BR BR9812139-1A patent/BR9812139A/pt not_active IP Right Cessation
- 1998-08-17 CN CN98810251A patent/CN1276833A/zh active Pending
- 1998-08-17 HU HU0004327A patent/HUP0004327A3/hu unknown
- 1998-08-17 AT AT98945269T patent/ATE267211T1/de not_active IP Right Cessation
- 1998-08-17 CA CA2301920A patent/CA2301920C/en not_active Expired - Fee Related
- 1998-08-19 UY UY25146A patent/UY25146A1/es not_active Application Discontinuation
- 1998-08-20 CO CO98047511A patent/CO4810234A1/es unknown
- 1998-08-21 ZA ZA9807591A patent/ZA987591B/xx unknown
- 1998-08-21 MA MA25223A patent/MA24638A1/fr unknown
-
2000
- 2000-02-21 NO NO20000850A patent/NO20000850L/no not_active Application Discontinuation
-
2001
- 2001-11-01 US US10/000,903 patent/US20020182221A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69824013T2 (de) | 2005-06-02 |
| DE69824013D1 (de) | 2004-06-24 |
| CA2301920A1 (en) | 1999-03-04 |
| NZ502632A (en) | 2002-03-28 |
| IL134392A0 (en) | 2001-04-30 |
| ZA987591B (en) | 2000-02-21 |
| AU732946B2 (en) | 2001-05-03 |
| JP2001513986A (ja) | 2001-09-11 |
| CN1276833A (zh) | 2000-12-13 |
| WO1999010375A2 (en) | 1999-03-04 |
| NO20000850L (no) | 2000-04-14 |
| EP1007551B1 (en) | 2004-05-19 |
| NO20000850D0 (no) | 2000-02-21 |
| PL339009A1 (en) | 2000-12-04 |
| GB9717953D0 (en) | 1997-10-29 |
| US6342224B1 (en) | 2002-01-29 |
| MA24638A1 (fr) | 1999-04-01 |
| ATE267211T1 (de) | 2004-06-15 |
| HUP0004327A1 (en) | 2001-03-28 |
| AU9263998A (en) | 1999-03-16 |
| HUP0004327A3 (en) | 2003-08-28 |
| CA2301920C (en) | 2011-01-04 |
| UY25146A1 (es) | 2000-12-29 |
| BR9812139A (pt) | 2000-07-18 |
| KR20010023193A (ko) | 2001-03-26 |
| ES2221198T3 (es) | 2004-12-16 |
| US20020182221A1 (en) | 2002-12-05 |
| WO1999010375A3 (en) | 1999-06-10 |
| CO4810234A1 (es) | 1999-06-30 |
| EP1007551A2 (en) | 2000-06-14 |
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