TR200000671T2 - FP agonistleri olarak yararlı aromatik C16-C20-ikameli tetrahidro prostaglandinler. - Google Patents

FP agonistleri olarak yararlı aromatik C16-C20-ikameli tetrahidro prostaglandinler.

Info

Publication number
TR200000671T2
TR200000671T2 TR2000/00671T TR200000671T TR200000671T2 TR 200000671 T2 TR200000671 T2 TR 200000671T2 TR 2000/00671 T TR2000/00671 T TR 2000/00671T TR 200000671 T TR200000671 T TR 200000671T TR 200000671 T2 TR200000671 T2 TR 200000671T2
Authority
TR
Turkey
Prior art keywords
compounds
agonists
aromatic
substituted tetrahydro
useful
Prior art date
Application number
TR2000/00671T
Other languages
English (en)
Inventor
August Wos John
Anthony Delong Mitchell
S. Amburgey Jack Jr.
De Biswanath
George Dai Haiyan
Wang Yili
Original Assignee
The Procter & Gamble Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Procter & Gamble Company filed Critical The Procter & Gamble Company
Publication of TR200000671T2 publication Critical patent/TR200000671T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Bulus yeni PGF analoglari sunmaktadir. Özellikle bu bulus bir formül (A) yapisini haiz bilesiklere iliskindir: burada R1, R2, R3, R4, X, Y ve Z tanimlandigi gibidir. Bu bulus ayrica adi geçen formülün optik izomerlerini, diastereomerlerini ve enantiomerlerini ve farmasötik olarak kabul edilebilir tuzlarini, biyohidrolize edilebilir amitlerini, esterlerini ve imitlerini kapsamaktadir. Bu bulusun bilesikleri kemik bozukluklari ve glokom gibi çesitli hastaliklarin ve durumlarin tedavisi için yararlidir. Bu nedenle bulus ayrica bu bilesikleri içeren farmasötik bilesimleri sunmaktadir. Bulus ayrica bu bilesikleri veya bunlari içeren bilesimseri kullanarak kemik bozukluklarini ve glokomu tedavi etmek için yöntemler sunmaktadir.
TR2000/00671T 1997-09-09 1998-09-04 FP agonistleri olarak yararlı aromatik C16-C20-ikameli tetrahidro prostaglandinler. TR200000671T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5821797P 1997-09-09 1997-09-09

Publications (1)

Publication Number Publication Date
TR200000671T2 true TR200000671T2 (tr) 2000-07-21

Family

ID=22015427

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/00671T TR200000671T2 (tr) 1997-09-09 1998-09-04 FP agonistleri olarak yararlı aromatik C16-C20-ikameli tetrahidro prostaglandinler.

Country Status (24)

Country Link
US (1) US5977173A (tr)
EP (1) EP1012136B1 (tr)
JP (1) JP2001515882A (tr)
KR (1) KR20010023839A (tr)
CN (1) CN1269786A (tr)
AR (1) AR013477A1 (tr)
AT (1) ATE270660T1 (tr)
AU (1) AU731153B2 (tr)
BR (1) BR9811774A (tr)
CA (1) CA2303764C (tr)
CO (1) CO4970731A1 (tr)
DE (1) DE69824966T2 (tr)
ES (1) ES2223141T3 (tr)
HU (1) HUP0100638A3 (tr)
ID (1) ID23971A (tr)
IL (1) IL134839A0 (tr)
NO (1) NO20001141L (tr)
NZ (1) NZ503735A (tr)
PE (1) PE115499A1 (tr)
PL (1) PL339212A1 (tr)
SK (1) SK3372000A3 (tr)
TR (1) TR200000671T2 (tr)
WO (1) WO1999012895A1 (tr)
ZA (1) ZA988230B (tr)

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EP2214482A4 (en) 2007-10-31 2011-08-24 Pamela Lipkin COMPOSITIONS OF PROSTAGLANDIN ANALOGUES AND METHODS OF TREATING EPITHELIAL STATES
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JP2012507552A (ja) 2008-10-29 2012-03-29 アエリエ・ファーマシューティカルズ・インコーポレーテッド プロスタグラジンのアミノ酸塩
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
KR101172638B1 (ko) 2008-12-30 2012-08-08 조선대학교산학협력단 신규한 티아졸리딘디온 유도체 및 그의 용도
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
EP3828172A1 (en) 2009-05-01 2021-06-02 Aerie Pharmaceuticals, Inc. Dual mechanism inhibitors for the treatment of disease
US9149484B2 (en) 2009-11-09 2015-10-06 Allergan, Inc. Compositions and methods for stimulating hair growth
EP3421030A1 (en) 2009-11-09 2019-01-02 Allergan, Inc. Compositions and methods for stimulating hair growth
US8859616B2 (en) 2011-01-21 2014-10-14 Allergan, Inc. Compounds and methods for enhancing hair growth
US20140275160A1 (en) 2013-03-15 2014-09-18 Aerie Pharmaceuticals, Inc. Combination therapy
US9643927B1 (en) 2015-11-17 2017-05-09 Aerie Pharmaceuticals, Inc. Process for the preparation of kinase inhibitors and intermediates thereof
CN109640966A (zh) 2016-08-31 2019-04-16 爱瑞制药公司 眼用组合物
WO2018183911A1 (en) 2017-03-31 2018-10-04 Aerie Pharmaceuticals, Inc. Aryl cyclopropyl-amino-isoquinolinyl amide compounds
US11427563B2 (en) 2018-09-14 2022-08-30 Aerie Pharmaceuticals, Inc. Aryl cyclopropyl-amino-isoquinolinyl amide compounds

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Also Published As

Publication number Publication date
SK3372000A3 (en) 2000-10-09
BR9811774A (pt) 2000-08-29
HUP0100638A3 (en) 2002-12-28
NO20001141L (no) 2000-05-04
AR013477A1 (es) 2000-12-27
DE69824966D1 (de) 2004-08-12
KR20010023839A (ko) 2001-03-26
DE69824966T2 (de) 2005-04-07
PE115499A1 (es) 2000-02-03
JP2001515882A (ja) 2001-09-25
CA2303764C (en) 2005-02-15
PL339212A1 (en) 2000-12-04
WO1999012895A1 (en) 1999-03-18
CN1269786A (zh) 2000-10-11
AU731153B2 (en) 2001-03-22
CA2303764A1 (en) 1999-03-18
HUP0100638A2 (hu) 2001-07-30
AU9219398A (en) 1999-03-29
ATE270660T1 (de) 2004-07-15
US5977173A (en) 1999-11-02
ID23971A (id) 2000-06-14
IL134839A0 (en) 2001-05-20
CO4970731A1 (es) 2000-11-07
ES2223141T3 (es) 2005-02-16
EP1012136A1 (en) 2000-06-28
ZA988230B (en) 1999-03-09
NO20001141D0 (no) 2000-03-06
EP1012136B1 (en) 2004-07-07
NZ503735A (en) 2001-05-25

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