MA26734A1 - Derives de 1-trifluoromethyl -4-hydroxy- 7-piperidinyl- aminomethylchromane, procede pour leur preparation et compositions pharmaceutiques les contenant - Google Patents

Derives de 1-trifluoromethyl -4-hydroxy- 7-piperidinyl- aminomethylchromane, procede pour leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
MA26734A1
MA26734A1 MA25978A MA25978A MA26734A1 MA 26734 A1 MA26734 A1 MA 26734A1 MA 25978 A MA25978 A MA 25978A MA 25978 A MA25978 A MA 25978A MA 26734 A1 MA26734 A1 MA 26734A1
Authority
MA
Morocco
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
aminomethylchromane
piperidinyl
Prior art date
Application number
MA25978A
Other languages
English (en)
Inventor
Scott Obach Ronald
Alan Scully Douglas
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MA26734A1 publication Critical patent/MA26734A1/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Nutrition Science (AREA)
  • Otolaryngology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)

Abstract

L'INVENTION CONCERNE DES COMPOSÉS DE FORMULE . DANS LAQUELLE R1, R2, R3, R4 ET R5 REPRÉSENTENT DIVERS RADICAUX . ELLE CONCERNE ÉGALEMENT UN PROCÉDÉ POUR LEUR PRÉPARATION ET DES COMPOSITION PHARMACEUTIQUES LES CONTENANT. - APPLICATION : UTILISATION DE CES COMPOSÉS ET COMPOSITIONS, COMME ANTAGONISTES DE LA SUBSTANCE P, POUR LE TRAITEMENT DE DIVERSES MALADIES.
MA25978A 1999-05-21 2000-05-17 Derives de 1-trifluoromethyl -4-hydroxy- 7-piperidinyl- aminomethylchromane, procede pour leur preparation et compositions pharmaceutiques les contenant MA26734A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13539999P 1999-05-21 1999-05-21

Publications (1)

Publication Number Publication Date
MA26734A1 true MA26734A1 (fr) 2004-12-20

Family

ID=22467939

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25978A MA26734A1 (fr) 1999-05-21 2000-05-17 Derives de 1-trifluoromethyl -4-hydroxy- 7-piperidinyl- aminomethylchromane, procede pour leur preparation et compositions pharmaceutiques les contenant

Country Status (49)

Country Link
US (1) US6239147B1 (fr)
EP (1) EP1178984B1 (fr)
JP (1) JP3802762B2 (fr)
KR (1) KR100453301B1 (fr)
CN (1) CN1140525C (fr)
AP (1) AP1396A (fr)
AR (1) AR020294A1 (fr)
AT (1) ATE234832T1 (fr)
AU (1) AU775861B2 (fr)
BG (1) BG106152A (fr)
BR (1) BR0011284A (fr)
CA (1) CA2374643C (fr)
CO (1) CO5170464A1 (fr)
CR (1) CR6503A (fr)
CZ (1) CZ20014164A3 (fr)
DE (1) DE60001736T2 (fr)
DK (1) DK1178984T3 (fr)
DZ (1) DZ3044A1 (fr)
EA (1) EA004233B1 (fr)
EE (1) EE04719B1 (fr)
ES (1) ES2190781T3 (fr)
GC (1) GC0000254A (fr)
GE (1) GEP20043225B (fr)
GT (1) GT200000073A (fr)
HK (1) HK1046280B (fr)
HN (1) HN2000000057A (fr)
HR (1) HRP20010861A2 (fr)
HU (1) HUP0201443A3 (fr)
IL (1) IL145949A0 (fr)
IS (1) IS6123A (fr)
MA (1) MA26734A1 (fr)
MX (1) MXPA01011977A (fr)
MY (1) MY123373A (fr)
NO (1) NO322496B1 (fr)
NZ (1) NZ514698A (fr)
OA (1) OA11944A (fr)
PA (1) PA8495201A1 (fr)
PE (1) PE20010165A1 (fr)
PL (1) PL198658B1 (fr)
PT (1) PT1178984E (fr)
SK (1) SK285819B6 (fr)
SV (1) SV2002000077A (fr)
TN (1) TNSN00105A1 (fr)
TR (1) TR200103332T2 (fr)
TW (1) TWI275588B (fr)
UA (1) UA71004C2 (fr)
UY (1) UY26147A1 (fr)
WO (1) WO2000071538A2 (fr)
ZA (1) ZA200109554B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
PT1095939E (pt) * 1999-10-18 2004-04-30 Pfizer Prod Inc Processo para a preparacao de eteres ciclicos de compostos com piperidinilaminometilo
DE10311984A1 (de) * 2003-03-12 2004-09-23 Freie Universität Berlin Verwendung von NEP-assoziierten Molekülen zur Behandlung von nichtimmunogenen-nichthypertensiven Zivilisationskrankheiten
US7122700B2 (en) * 2004-07-30 2006-10-17 Xerox Corporation Arylamine processes
US7868016B2 (en) * 2005-07-13 2011-01-11 Baxter International Inc. Pharmaceutical formulations of endo-N-(9-methyl-9-azabicyclo[3,3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide hydrochloride
WO2009109001A1 (fr) * 2008-03-04 2009-09-11 Adelaide Research & Innovation Pty Ltd Procédé de prévention et/ou de traitement d’une maladie, d’une condition ou d’un état associés à une fonction réduite des neurones dopaminergiques
ES2582161T3 (es) 2008-06-25 2016-09-09 Array Biopharma, Inc. Derivados del ácido fenoxicroman carboxílico sustituidos en 6
CN117343036A (zh) * 2023-03-20 2024-01-05 江苏联环药业股份有限公司 异苯并二氢吡喃类化合物及其药物组合物和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
GB9317987D0 (en) * 1993-08-26 1993-10-13 Glaxo Group Ltd Chemical compounds
DE69617226T2 (de) * 1995-03-27 2002-07-25 Hisamitsu Pharmaceutical Co., Inc. Piperidinderivate.
RU2156250C2 (ru) * 1995-04-24 2000-09-20 Новартис Аг Производные хромона, способ их получения и фармацевтическая композиция
JP3042894B2 (ja) * 1995-07-07 2000-05-22 ファイザー製薬株式会社 サブスタンスｐアンタゴニストとしての置換ベンゾラクタム化合物
TW340842B (en) * 1995-08-24 1998-09-21 Pfizer Substituted benzylaminopiperidine compounds
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists

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DK1178984T3 (da) 2003-06-10
MXPA01011977A (es) 2002-05-06
BR0011284A (pt) 2002-03-05
OA11944A (en) 2006-04-12
PA8495201A1 (es) 2002-08-26
SV2002000077A (es) 2002-07-03
HK1046280B (zh) 2004-10-21
CN1355799A (zh) 2002-06-26
EP1178984A2 (fr) 2002-02-13
HN2000000057A (es) 2001-03-02
AP1396A (en) 2005-04-19
AU775861B2 (en) 2004-08-19
NZ514698A (en) 2005-01-28
KR100453301B1 (ko) 2004-10-20
UY26147A1 (es) 2000-12-29
IL145949A0 (en) 2002-07-25
PE20010165A1 (es) 2001-02-20
US6239147B1 (en) 2001-05-29
TWI275588B (en) 2007-03-11
ZA200109554B (en) 2002-11-20
BG106152A (en) 2002-06-28
DE60001736T2 (de) 2003-09-18
IS6123A (is) 2001-10-23
CA2374643C (fr) 2006-02-14
MY123373A (en) 2006-05-31
CZ20014164A3 (cs) 2003-01-15
TNSN00105A1 (fr) 2005-11-10
EA004233B1 (ru) 2004-02-26
HRP20010861A2 (en) 2003-04-30
EE04719B1 (et) 2006-10-16
AU3667300A (en) 2000-12-12
UA71004C2 (uk) 2004-11-15
EA200101109A1 (ru) 2002-04-25
JP2003500405A (ja) 2003-01-07
PL198658B1 (pl) 2008-07-31
PL352409A1 (en) 2003-08-25
DE60001736D1 (de) 2003-04-24
ES2190781T3 (es) 2003-08-16
TR200103332T2 (tr) 2002-04-22
AR020294A1 (es) 2002-05-02
HUP0201443A2 (en) 2002-08-28
NO20015652L (no) 2002-01-14
GT200000073A (es) 2001-11-09
WO2000071538A2 (fr) 2000-11-30
CR6503A (es) 2004-02-03
PT1178984E (pt) 2003-06-30
GC0000254A (en) 2006-11-01
KR20020016793A (ko) 2002-03-06
EP1178984B1 (fr) 2003-03-19
WO2000071538A3 (fr) 2001-02-22
EE200100612A (et) 2003-02-17
HK1046280A1 (en) 2003-01-03
CA2374643A1 (fr) 2000-11-30
ATE234832T1 (de) 2003-04-15
CN1140525C (zh) 2004-03-03
DZ3044A1 (fr) 2004-03-27
CO5170464A1 (es) 2002-06-27
NO322496B1 (no) 2006-10-16
AP2001002327A0 (en) 2001-12-31
NO20015652D0 (no) 2001-11-20
SK16592001A3 (sk) 2003-03-04
HUP0201443A3 (en) 2005-09-28
SK285819B6 (sk) 2007-09-06
GEP20043225B (en) 2004-04-26
JP3802762B2 (ja) 2006-07-26

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