TR200001021T2 - Aktif maddelerin kontrollü salınması için biyo aşındırılabilir makromerler. - Google Patents

Aktif maddelerin kontrollü salınması için biyo aşındırılabilir makromerler.

Info

Publication number
TR200001021T2
TR200001021T2 TR2000/01021T TR200001021T TR200001021T2 TR 200001021 T2 TR200001021 T2 TR 200001021T2 TR 2000/01021 T TR2000/01021 T TR 2000/01021T TR 200001021 T TR200001021 T TR 200001021T TR 200001021 T2 TR200001021 T2 TR 200001021T2
Authority
TR
Turkey
Prior art keywords
controlled release
active substances
biodegradable macromers
biologically active
macromers
Prior art date
Application number
TR2000/01021T
Other languages
English (en)
Inventor
A. Hubbell Jeffrey
T. Kieras Mark
S.Ron Eyal
C. Rowe Stephan
Original Assignee
Infimed Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infimed Inc. filed Critical Infimed Inc.
Publication of TR200001021T2 publication Critical patent/TR200001021T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

Biyolojik olarak aktif bir maddenin verilmesi için bir metod açiklanmaktadir, su asamalari içerir;(a) sözü edilen biyolojik olarak aktif maddenin bir makromer ile birlestirilmesi,(b) önceki asama (a)'da olusturulan kombinasyonun bir karisiminin, (c) sözü edilen karisimin polimerlestirilmesi ve (d) sözü edilen madde ya da onun bir parçasinin bir memeliye uygulanmasi, burda asama (c) bir polimerlestirilebilir monovinil monomer olmadan gerçeklesir.
TR2000/01021T 1997-07-18 1998-07-17 Aktif maddelerin kontrollü salınması için biyo aşındırılabilir makromerler. TR200001021T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5302997P 1997-07-18 1997-07-18

Publications (1)

Publication Number Publication Date
TR200001021T2 true TR200001021T2 (tr) 2000-09-21

Family

ID=21981471

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/01021T TR200001021T2 (tr) 1997-07-18 1998-07-17 Aktif maddelerin kontrollü salınması için biyo aşındırılabilir makromerler.

Country Status (13)

Country Link
US (3) US6153211A (tr)
EP (1) EP1019031A4 (tr)
JP (1) JP2001510151A (tr)
KR (1) KR20010022007A (tr)
CN (1) CN1271277A (tr)
AU (1) AU748756B2 (tr)
BR (1) BR9811793A (tr)
CA (1) CA2296459A1 (tr)
GE (1) GEP20022707B (tr)
IL (1) IL134084A0 (tr)
NZ (1) NZ502358A (tr)
TR (1) TR200001021T2 (tr)
WO (1) WO1999003454A1 (tr)

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US20040197369A1 (en) 2004-10-07
CA2296459A1 (en) 1999-01-28
WO1999003454A9 (en) 1999-04-22
GEP20022707B (en) 2002-06-25
IL134084A0 (en) 2001-04-30
BR9811793A (pt) 2000-09-26
US6703037B1 (en) 2004-03-09
JP2001510151A (ja) 2001-07-31
EP1019031A1 (en) 2000-07-19
KR20010022007A (ko) 2001-03-15
NZ502358A (en) 2002-11-26
US6153211A (en) 2000-11-28
CN1271277A (zh) 2000-10-25
AU748756B2 (en) 2002-06-13
EP1019031A4 (en) 2003-02-05
AU8490498A (en) 1999-02-10

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