TR200100873T2 - Klavülanik asitin kontrol edilen bir amonyak seviyesinde mayalanması - Google Patents
Klavülanik asitin kontrol edilen bir amonyak seviyesinde mayalanmasıInfo
- Publication number
- TR200100873T2 TR200100873T2 TR2001/00873T TR200100873T TR200100873T2 TR 200100873 T2 TR200100873 T2 TR 200100873T2 TR 2001/00873 T TR2001/00873 T TR 2001/00873T TR 200100873 T TR200100873 T TR 200100873T TR 200100873 T2 TR200100873 T2 TR 200100873T2
- Authority
- TR
- Turkey
- Prior art keywords
- clavulanic acid
- fermentation
- ammonia level
- controlled ammonia
- controlled
- Prior art date
Links
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 title abstract 4
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title abstract 4
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title abstract 4
- 229960003324 clavulanic acid Drugs 0.000 title abstract 4
- 229910021529 ammonia Inorganic materials 0.000 title abstract 2
- 238000000855 fermentation Methods 0.000 title abstract 2
- 230000004151 fermentation Effects 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Bir klavülanik asit üreten mikroorganizmanin kontrol edilen en az 50 mg/l'lik amonyak düzeyinde mayalanmasi ile klavülanik asitin üretilmesi için bir yöntem tedarik edilmistir. Bu tepkime kosullarinin uygulanmasi ile, sasirtici olarak yüksek üretim düzeylerinde klavülanik asit elde edilmistir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98203314 | 1998-09-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200100873T2 true TR200100873T2 (tr) | 2001-07-23 |
Family
ID=8234177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/00873T TR200100873T2 (tr) | 1998-09-29 | 1999-09-23 | Klavülanik asitin kontrol edilen bir amonyak seviyesinde mayalanması |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1117820A1 (tr) |
| CN (1) | CN1198940C (tr) |
| AU (1) | AU6089699A (tr) |
| CA (1) | CA2342181A1 (tr) |
| TR (1) | TR200100873T2 (tr) |
| WO (1) | WO2000018947A1 (tr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102933717A (zh) * | 2007-04-27 | 2013-02-13 | 科学与工业研究委员会 | 在固态发酵中采用棒状链霉菌mtcc 1142制备棒酸的方法 |
| RU2628696C1 (ru) * | 2013-10-02 | 2017-08-21 | Адзиномото Ко., Инк. | Способ получения основной аминокислоты (варианты) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0026044B1 (en) * | 1979-08-24 | 1983-06-08 | Beecham Group Plc | Amine salt of clavulanic acid, its preparation and use |
| GB9424950D0 (en) * | 1994-12-10 | 1995-02-08 | Smithkline Beecham Plc | Novel process |
| SI9600120A (en) * | 1996-04-12 | 1997-12-31 | Lek Tovarna Farmacevtskih | New and improved fermentative procedure for the production of clavulanic acid and its salts |
-
1999
- 1999-09-23 TR TR2001/00873T patent/TR200100873T2/tr unknown
- 1999-09-23 CN CN 99811511 patent/CN1198940C/zh not_active Expired - Fee Related
- 1999-09-23 CA CA002342181A patent/CA2342181A1/en not_active Abandoned
- 1999-09-23 EP EP99947466A patent/EP1117820A1/en not_active Withdrawn
- 1999-09-23 AU AU60896/99A patent/AU6089699A/en not_active Abandoned
- 1999-09-23 WO PCT/EP1999/007390 patent/WO2000018947A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1117820A1 (en) | 2001-07-25 |
| CA2342181A1 (en) | 2000-04-06 |
| AU6089699A (en) | 2000-04-17 |
| WO2000018947A1 (en) | 2000-04-06 |
| CN1198940C (zh) | 2005-04-27 |
| CN1320166A (zh) | 2001-10-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FR2379531A1 (fr) | Nouvelle substance physiologiquement active inhibant l'activite enzymatique de l'esterase et son mode de production | |
| EP0625571A3 (de) | Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-Alpha-Aminosäuren. | |
| EP0464325A3 (en) | Process for the preparation of l-ornithine salts | |
| DE60029232D1 (de) | Verbessertes fermentationsverfahren | |
| DE69320984D1 (de) | Herstellung von isomerisiertem hopfenextrakt | |
| ES8800362A1 (es) | Un procedimiento para la preparacion del complejo antibiotico a-21978 c o sus factores c0,c1,c2,c3,c4, 0 c5. | |
| TR200100873T2 (tr) | Klavülanik asitin kontrol edilen bir amonyak seviyesinde mayalanması | |
| GB1523835A (en) | Process for maximising the growth and nicotine degrading activity of microorganismus | |
| MY116591A (en) | Process for the production of lipstatin and tetrahydrolipstatin | |
| ZA200107763B (en) | Process for producing non-proteinogenic L-amino acids by fermentation. | |
| NO180594C (no) | Fremgangsmåte for kontinuerlig omsetning av cefalosporinderivater til glutaryl-7-aminocefalosporansyrederivater | |
| TR200003828T2 (tr) | Düşük bir serbest amino asiti konsantrasyonunda klavülanik asitin üretilmesi için fermentasyon işlemi | |
| ES2094389T3 (es) | Produccion de diacetilo. | |
| ATE288962T1 (de) | Verbessertes verfahren zur fermentativen herstellung von cephalosporin | |
| SE8202201L (sv) | Forfarande for intjockning av biologiskt slam, serskilt aktivt slam | |
| DE69718360D1 (de) | Aldehyd Dehydrogenase | |
| RU97102081A (ru) | Штамм mucor circinelloides var. lusitanicus продуцент витамина-f и способ получения витамина-f | |
| ITMI940418A1 (it) | Procedimento per la conversione della cefalosporina c in acido glutaril - 7 amminocefalosporanico | |
| RU92001712A (ru) | Способ получения красителя | |
| TR200100167T2 (tr) | Klavulanik asit üretimi için geliştirilmiş yöntem | |
| SU871525A1 (ru) | Способ получени НАД-зависимой формиатдегидрогеназы | |
| SU654679A1 (ru) | Способ приготовлени питательного субстрата дл производства кормовых дрожжей | |
| ES482625A1 (es) | Procedimiento para producir un jarabe de elevado contenido de dextrosa. | |
| JPS5819275B2 (ja) | α−メチル−L−ド−パの製造法 | |
| JPS5722693A (en) | Preparation of mycophenolic acid |