TR200101032T2 - Bitkilerdeki sağaltıcı yönden aktif proteinler. - Google Patents

Bitkilerdeki sağaltıcı yönden aktif proteinler.

Info

Publication number
TR200101032T2
TR200101032T2 TR2001/01032T TR200101032T TR200101032T2 TR 200101032 T2 TR200101032 T2 TR 200101032T2 TR 2001/01032 T TR2001/01032 T TR 2001/01032T TR 200101032 T TR200101032 T TR 200101032T TR 200101032 T2 TR200101032 T2 TR 200101032T2
Authority
TR
Turkey
Prior art keywords
plants
active proteins
host
healing active
present
Prior art date
Application number
TR2001/01032T
Other languages
English (en)
Inventor
Bernard Heifetz Peter
Arthur Goff Stephen
Bloom Tuttle Annmarie
Else Griot-Wenk Monika
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of TR200101032T2 publication Critical patent/TR200101032T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8214—Plastid transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Environmental Sciences (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pain & Pain Management (AREA)

Abstract

Mevcut bulus, sagaltici yönden aktif proteinleri, tercihen plastit genomundan ya da vaküole hedefleyerek ekspresyona tabi tutan transjenik bitkileri ifsa eder. Mevcut bulus, ayrica bu gibi transjenik bitkilerin ihtiyaç halindeki bir konakçiya hastaliklarin önlenmesi ya da tedavi edilmesi için tatbik edilmesini tarif eder. Tercih edilen bir bulus biçimi itibariyla, bu gibi bitkiler ya da bunlardan türetilen maddeler bir konakçiya oral yoldan tatbik edilir.
TR2001/01032T 1998-10-07 1999-10-05 Bitkilerdeki sağaltıcı yönden aktif proteinler. TR200101032T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16736298A 1998-10-07 1998-10-07
US16823198A 1998-10-07 1998-10-07

Publications (1)

Publication Number Publication Date
TR200101032T2 true TR200101032T2 (tr) 2001-10-22

Family

ID=26863095

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/01032T TR200101032T2 (tr) 1998-10-07 1999-10-05 Bitkilerdeki sağaltıcı yönden aktif proteinler.

Country Status (14)

Country Link
EP (1) EP1117817A2 (tr)
JP (1) JP2002526116A (tr)
KR (1) KR20010085901A (tr)
CN (1) CN1330718A (tr)
AR (1) AR020717A1 (tr)
AU (2) AU758817B2 (tr)
BR (1) BR9915919A (tr)
CA (1) CA2344269A1 (tr)
HU (1) HUP0103616A3 (tr)
IL (1) IL142041A0 (tr)
PL (1) PL347904A1 (tr)
RU (2) RU2001111881A (tr)
TR (1) TR200101032T2 (tr)
WO (1) WO2000020612A2 (tr)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL155588A0 (en) * 2003-04-27 2003-11-23 Metabogal Ltd Methods for expression of enzymatically active recombinant lysosomal enzymes in transgenic plant root cells and vectors used thereby
US20050032211A1 (en) * 1996-09-26 2005-02-10 Metabogal Ltd. Cell/tissue culturing device, system and method
US7361331B2 (en) * 1996-10-18 2008-04-22 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Plant bioreactors
AR024934A1 (es) * 1999-07-27 2002-10-30 Novartis Ag Genes quimericos
US7572466B1 (en) 1999-10-13 2009-08-11 Health Research, Inc. Oral immunology using plant product containing a non-enteric pathogen antigen
AU2001245358A1 (en) * 2000-02-29 2001-09-12 Auburn University Production of antibodies in transgenic plastids
AU2001252246A1 (en) * 2000-04-05 2001-10-23 Syngenta Participations Ag Therapeutically active proteins in plants
FR2809413B1 (fr) * 2000-05-29 2004-10-22 Tabacs & Allumettes Ind Production d'allergenes recombinants dans des cellules vegetales
JP2002017186A (ja) * 2000-06-30 2002-01-22 Hayashibara Biochem Lab Inc トランスジェニック植物
GB2364705A (en) * 2000-07-14 2002-02-06 Icgeb Fusion protein expression in plastids
WO2002014523A2 (en) 2000-08-11 2002-02-21 Syngenta Participations Ag Methods for stable transformation of plants
BR0208880A (pt) * 2001-04-13 2004-12-07 Thompson Boyce Plant Res Métodos para produzir um homogeneizado seco estável de uma planta transgênica que expressa uma proteìna heteróloga, para prevenir uma doença patogênica em um animal, para liberar uma proteìna transgênica a um animal, de contracepção e para induzir uma resposta imune mucosal, homogeneizado seco estável, composição farmacêutica, planta transgênica, célula de planta, vetor plasmìdico para transformar uma célula de planta, composição de alimento, e, alimento
WO2003091413A2 (en) * 2002-04-23 2003-11-06 The Scripps Research Institute Expression of polypeptides in chloroplasts, and compositions and methods for expressing same
FR2841906B1 (fr) * 2002-07-05 2006-08-18 Stallergenes Sa Molecule d'acide nucleique codant une preproproteine d'allergene d'un acarien du genre dermatophagoides ou euroglyphus et son utilisation pour la production dudit allergene dans les plantes
EP1554387B1 (en) 2002-10-15 2012-01-25 Syngenta Participations AG Plastid transformation
WO2004070016A2 (en) 2003-02-03 2004-08-19 Fraunhofer Usa Inc. System for expression of genes in plants
WO2004074491A2 (en) * 2003-02-18 2004-09-02 Syngeta Participations Ag Expression in plants of antibodies against enterotoxigenic escherichia coli
GB0307989D0 (en) * 2003-04-07 2003-05-14 Mcewen Lab Ltd Therapeutic composition
US7951557B2 (en) 2003-04-27 2011-05-31 Protalix Ltd. Human lysosomal proteins from plant cell culture
BRPI0410562B8 (pt) 2003-05-22 2021-05-25 Fralunhofer Usa Inc proteína de veículo e seu método de produção em uma planta, ácido nucleico isolado, vetor de expressão e célula hospedeira
RU2259846C1 (ru) * 2004-06-10 2005-09-10 Федоскова Татьяна Германовна Средство и способ специфической иммунотерапии больных аллергическими заболеваниями, имеющих сенсибилизацию к укусам комаров
US8455717B2 (en) 2004-09-29 2013-06-04 Collplant Ltd. Collagen producing plants and methods of generating and using same
KR20080038131A (ko) * 2005-07-18 2008-05-02 프로탈릭스 리미티드 생물학적으로 활성인 거대분자의 점막 또는 장관 투여
AU2012241058B2 (en) * 2005-07-18 2014-04-17 Protalix Ltd. Mucosal or Enteral Administration of Biologically Active Macromolecules
CA2616859C (en) 2005-08-03 2015-04-14 Fraunhofer Usa, Inc. Compositions and methods for production of immunoglobulins
JP2009526526A (ja) 2006-02-13 2009-07-23 フラウンホーファー ユーエスエー， インコーポレイテッド インフルエンザ抗原、ワクチン組成物、および関連する方法
GB0604966D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Medicaments and proteins
GB0604938D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Proteins, nucleic acids and medicaments
GB0604964D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Protein folding
GB0617816D0 (en) * 2006-09-11 2006-10-18 Renovo Ltd Nucleic acids and methods of protein expression
ES2660667T3 (es) 2007-05-07 2018-03-23 Protalix Ltd. Biorreactor desechable a gran escala
GB2449466B (en) * 2007-05-23 2009-11-18 Algentech Ltd Production of proteins in plant tissue
WO2009009759A2 (en) 2007-07-11 2009-01-15 Fraunhofer Usa, Inc. Yersinia pestis antigens, vaccine compositions, and related methods
WO2009058355A2 (en) * 2007-10-31 2009-05-07 University Of Central Florida Research Foundation, Inc. Chloroplast-derived human vaccine antigens against malaria
US20110195112A1 (en) * 2008-06-30 2011-08-11 Bjorn Larus Orvar Use of plant-derived recombinant growth factors in skin care
US8734803B2 (en) 2008-09-28 2014-05-27 Ibio Inc. Humanized neuraminidase antibody and methods of use thereof
WO2010061404A1 (en) * 2008-11-27 2010-06-03 International Centre For Genetic Engineering And Biotechnology A method of expressing foreign protein in plastids
US9551005B2 (en) * 2009-07-16 2017-01-24 Kenneth John Piller Immunoassay for detecting thyroglobulin utilizing soybean produced recombinant thyroglobulin
US8784819B2 (en) 2009-09-29 2014-07-22 Ibio Inc. Influenza hemagglutinin antibodies, compositions and related methods
AR079065A1 (es) * 2009-11-18 2011-12-21 Agriculture Victoria Serv Pty Expresion del gen de angiogenina en las plantas y su uso
BR112013031564B1 (pt) 2011-06-07 2021-11-03 Ibio, Inc Métodos para geração e expressão de um polipeptídio e sistema de expressão
JP2013040138A (ja) * 2011-08-17 2013-02-28 Univ Of Tsukuba 活性化型リコンビナント花粉アレルゲンの作製方法
WO2014030165A1 (en) * 2012-08-23 2014-02-27 Transalgae Israel Ltd. Transgenic microalgae and use thereof for oral delivery of proteins
WO2015121863A1 (en) 2014-02-12 2015-08-20 Transalgae Israel Ltd. Algal based edible vaccines
AU2015261440A1 (en) * 2014-05-14 2017-01-05 Barbara BURWINKEL Synthesis of double-stranded nucleic acids
FR3021328B1 (fr) * 2014-05-23 2018-01-05 Angany Inc. Production commerciale de l'allergene amb a1 par expression transitoire chez les plantes
CN104561353B (zh) * 2015-01-29 2017-01-11 中国农业科学院蔬菜花卉研究所 与甘蓝育性紧密连锁的InDel标记及其检测方法和应用
CN110603046B (zh) * 2016-03-20 2022-10-18 宾夕法尼亚州立大学托管会 用于提高高等植物叶绿体中转基因表达的密码子优化和核糖体图谱分析
CN120944941A (zh) * 2025-08-07 2025-11-14 中国热带农业科学院南亚热带作物研究所 菠萝钙依赖性蛋白激酶基因在菠萝水心病防治中的应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5451513A (en) * 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
GB9319429D0 (en) * 1993-09-21 1993-11-03 London Health Ass Methods and products for controlling immune responses in mammals
US5576198A (en) * 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
FR2736930B1 (fr) * 1995-07-17 1997-09-19 Biocem Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines
WO1997004123A1 (en) * 1995-07-19 1997-02-06 Gel Tech Group Inc. Collagen compound production in plants
ZA965786B (en) * 1995-07-19 1997-01-27 Kimberly Clark Co Nonwoven barrier and method of making the same
CA2225652C (en) * 1995-08-10 2007-11-20 Pal Maliga Nuclear-encoded transcription system in plastids of higher plants
BR9707948A (pt) * 1996-03-06 1999-07-27 Univ Rutgers Processo para obter plantas transplastômicas
AU4058497A (en) * 1996-08-09 1998-03-06 Calgene Llc Methods for producing carotenoid compounds and speciality oils in plant seeds
AU3825497A (en) * 1996-08-15 1998-03-06 Agrivax Incorporated Delivery of tolerogenic antigens via edible plants or plant-derived products
ATE299941T1 (de) * 1996-09-12 2005-08-15 Syngenta Participations Ag Cellulolytische enzyme-exprimierende transgene pflanzen
JP2002513283A (ja) * 1997-01-17 2002-05-08 ザ スクリップス リサーチ インスティテュート 組換え分子の発現に有用なｒｎａ結合タンパク質及び結合部位
WO1999010513A1 (en) * 1997-08-07 1999-03-04 Auburn University Universal chloroplast integration and expression vectors, transformed plants and products thereof
DK1097211T3 (da) * 1998-07-10 2007-06-04 Calgene Llc Ekspression af eukaryote peptider i planteplastider

Also Published As

Publication number Publication date
AU2003200126A9 (en) 2003-04-17
WO2000020612A2 (en) 2000-04-13
HUP0103616A3 (en) 2003-07-28
RU2001111881A (ru) 2003-06-20
AR020717A1 (es) 2002-05-22
AU758817B2 (en) 2003-04-03
BR9915919A (pt) 2001-08-21
PL347904A1 (en) 2002-04-22
EP1117817A2 (en) 2001-07-25
RU2003131696A (ru) 2005-04-20
KR20010085901A (ko) 2001-09-07
AU2003200126A1 (en) 2003-04-17
AU6334099A (en) 2000-04-26
CA2344269A1 (en) 2000-04-13
IL142041A0 (en) 2002-03-10
CN1330718A (zh) 2002-01-09
JP2002526116A (ja) 2002-08-20
HUP0103616A2 (hu) 2002-01-28
WO2000020612A3 (en) 2000-07-06

Similar Documents

Publication Publication Date Title
TR200101032T2 (tr) Bitkilerdeki sağaltıcı yönden aktif proteinler.
BR9914360A (pt) N-aralquilaminotetralinas como ligandos para oreceptor neuropeptìdeo yy5
BR0110961A (pt) Derivados de triazol
MXPA03002218A (es) Peptidos antimicrobianos y metodos de uso.
ATE361084T1 (de) Topische pharmazeutische zusammensetzungen mit proanthocyanidinen, glycyrrhetinic säure und telmesteine zur behandlung von dermatitis
EE03969B1 (et) (Metüülsulfonüül)fenüül-2-(5H)-furanoonid, nende kasutamine ja farmatseutilised kompositsioonid
SE9800836D0 (sv) New Compounds
IS6194A (is) Serínprótínasar úr fiski og notkun þeirra í lyf og snyrtivörur
BR0113663A (pt) Composições de pelìcula de pectina
EA200401471A1 (ru) Применение ингибиторов сетр и возможных ингибиторов hmg coa и/или антигипертензивных агентов
FR2714830B1 (fr) Composition contenant des acides nucléiques, préparation et utilisations.
DK0994710T3 (da) Farmaceutiske præparater til oral indgivelse omfattende en benzhydrylpiperazin og en cyclodextrin
PT1246809E (pt) Compostos de 5-aril-1h-1,2,4-triazole como inibidores de ciclooxigenase-2 e composicoes farmaceuticas que os contem
ATE297188T1 (de) Stabilisierte ascorbinsäure-lösungen
ATE549353T1 (de) Aktive varianten des il-18 bindenden proteins und dessen medizinische verwendungen
DE60142519D1 (de) Dna-expressionsvektoren
TR200100637T2 (tr) Yeni doğal ürün türevleri
NO20030802D0 (no) Aminoalkoksybenzoyl-benzofuran- eller benzotiofenderivater, fremgangsmåte for deres fremstilling og preparater inneholdende de samme
ATE247130T1 (de) Inhibitoren für den urokinaserezeptor
NO20020914L (no) Alkoksy-substituerte benzimidazolforbindelser, preparater inneholdende slike samt anvendelser derav
ATE555787T1 (de) Behandlungseffekte von überschüssigen reaktiven sauerstoffspezies
BR0113674A (pt) Peptìdeos antiangiogênicos
BR9810556A (pt) Beta-alcoxiacrilatos contra a malária
ATE263555T1 (de) Synergistisch wirkende zusammensetzungen zur selektiven bekämpfung von tumorgewebe
WO2002032445A3 (de) Hemmung der interaktion zwischen oxidierte proteine und cd36 oder dessen wirkmechanismus