TR200101344T2 - Propionil L-karnitinden ve bir flavonoid'den oluşan antioksidan bileşim - Google Patents
Propionil L-karnitinden ve bir flavonoid'den oluşan antioksidan bileşimInfo
- Publication number
- TR200101344T2 TR200101344T2 TR2001/01344T TR200101344T TR200101344T2 TR 200101344 T2 TR200101344 T2 TR 200101344T2 TR 2001/01344 T TR2001/01344 T TR 2001/01344T TR 200101344 T TR200101344 T TR 200101344T TR 200101344 T2 TR200101344 T2 TR 200101344T2
- Authority
- TR
- Turkey
- Prior art keywords
- flavonoid
- carnitine
- propionyl
- composition consisting
- antioxidant composition
- Prior art date
Links
- UFAHZIUFPNSHSL-MRVPVSSYSA-N O-propanoyl-L-carnitine Chemical compound CCC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C UFAHZIUFPNSHSL-MRVPVSSYSA-N 0.000 title abstract 2
- 229930003935 flavonoid Natural products 0.000 title abstract 2
- 150000002215 flavonoids Chemical class 0.000 title abstract 2
- 235000017173 flavonoids Nutrition 0.000 title abstract 2
- 239000003963 antioxidant agent Substances 0.000 title 1
- 230000003078 antioxidant effect Effects 0.000 title 1
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 abstract 2
- 235000015872 dietary supplement Nutrition 0.000 abstract 2
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 abstract 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 abstract 1
- 230000005856 abnormality Effects 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000003143 atherosclerotic effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229960001285 quercetin Drugs 0.000 abstract 1
- 235000005875 quercetin Nutrition 0.000 abstract 1
- 230000001732 thrombotic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
- A23L33/165—Complexes or chelates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Botany (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Serbest radikaller tarafindan ve trombotik ya da aterosklerotik anormallikler tarafindan baslatilan çesitli degisimlerin ve hastalik durumlarinin önlenmesi ve/ya da sagitici tedavisi için olan, aktif maddeler olarak propionil L-karnitin ve tipik olarak kersetin ya da bunun 3-rutinozid, rutini gibi bir flavonoid'i içermesiyle karakterize edilen, diyet katkisi, diyet takviyesi ya da gerçek bir ilaç seklinde alinabilen bir bilesim açiklanmaktadir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998RM000706A IT1302863B1 (it) | 1998-11-13 | 1998-11-13 | Composizione ad attivita' antiossidante e preventiva di alterazionitrombotiche e aterosclerotiche comprendente una carnitina ed un |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200101344T2 true TR200101344T2 (tr) | 2001-10-22 |
Family
ID=11406214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/01344T TR200101344T2 (tr) | 1998-11-13 | 1999-11-05 | Propionil L-karnitinden ve bir flavonoid'den oluşan antioksidan bileşim |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1128822B1 (tr) |
| AR (1) | AR021089A1 (tr) |
| AT (1) | ATE306258T1 (tr) |
| AU (1) | AU766402B2 (tr) |
| CA (1) | CA2350220C (tr) |
| CZ (1) | CZ20011609A3 (tr) |
| DE (1) | DE69927701T2 (tr) |
| DK (1) | DK1128822T3 (tr) |
| ES (1) | ES2249039T3 (tr) |
| HU (1) | HU229061B1 (tr) |
| IL (1) | IL143001A0 (tr) |
| IT (1) | IT1302863B1 (tr) |
| MA (1) | MA25592A1 (tr) |
| NO (1) | NO20012338L (tr) |
| PL (1) | PL201896B1 (tr) |
| SK (1) | SK6162001A3 (tr) |
| TN (1) | TNSN99212A1 (tr) |
| TR (1) | TR200101344T2 (tr) |
| WO (1) | WO2000028986A1 (tr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1316998B1 (it) | 2000-03-02 | 2003-05-26 | Sigma Tau Healthscience Spa | Composizione per la prevenzione e/o il trattamento degli effetticitotossici indotti dall'uso di agenti immunosoppressori. |
| IT1317035B1 (it) * | 2000-05-30 | 2003-05-26 | Sigma Tau Healthscience Spa | Integratore ad attivita' antiossidante comprendente unaalcanoilcarnitina ed una associazione di polifenoli estratti dal |
| US7338971B2 (en) * | 2001-08-30 | 2008-03-04 | El-Naggar Mawaheb M | Treatment of inflammatory, cancer, and thrombosis disorders |
| US6923960B2 (en) | 2001-10-03 | 2005-08-02 | Vsl Pharmaceuticals Inc. | Antioxidant combination composition and use thereof |
| GB0819960D0 (en) * | 2008-10-31 | 2008-12-10 | Provexis Natural Products Ltd | Therapeutic composition |
| EP2353596A1 (en) * | 2010-02-02 | 2011-08-10 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Combination composition, comprising as active ingredients L-carnitine or propionyl L-carnitine, for the prevention or treatment of chronic venous insufficiency |
| JP5923044B2 (ja) * | 2010-04-09 | 2016-05-24 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニＳｉｇｍａ−Ｔａｕ Ｉｎｄｕｓｔｒｉｅ Ｆａｒｍａｃｅｕｔｉｃｈｅ Ｒｉｕｎｉｔｅ Ｓｏｃｉｅｔａ Ｐｅｒ Ａｚｉｏｎｉ | 活性成分としてｌ−カルニチンまたはプロピオニルｌ−カルニチンを含む慢性静脈不全の予防または治療のための併用組成物 |
| US10391096B2 (en) * | 2011-10-13 | 2019-08-27 | Quercegen Pharmaceuticals Llc | Method for treating thrombotic disorders using quercetin-containing compositions |
| EP3886838A4 (en) | 2018-11-30 | 2022-08-10 | Beth Israel Deaconess Medical Center, Inc. | COMPOSITIONS AND METHODS FOR REDUCING MAJOR THROMBOTIC EVENTS IN CANCER PATIENTS |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1275434B (it) * | 1995-05-19 | 1997-08-07 | Farmila Farma Milano | Composizioni farmaceutiche e/o dietetiche ad attivita' antiossidante |
| DK0755633T3 (da) * | 1995-07-28 | 2000-04-17 | Herbert Schlachter | Tofasepræparat |
| CA2280093A1 (en) * | 1997-02-04 | 1998-08-06 | John V. Kosbab | Compositions and methods for prevention and treatment of vascular degenerative diseases |
| US5976568A (en) * | 1997-02-21 | 1999-11-02 | Medical Doctors' Research Institute, Inc. | Modular system of dietary supplement compositions for optimizing health benefits and methods |
| EP0928565B1 (de) * | 1997-12-17 | 2003-09-10 | Meta Handelsgesellschaft m.b.H. | Trinkflüssigkeit |
| DE19806890A1 (de) * | 1998-02-19 | 1999-08-26 | Beiersdorf Ag | Kosmetische und dermatologische Wirkstoffkombinationen aus mindestens einer Substanz gewählt aus der Gruppe, bestehend aus Carnitin und den Acylcarnitinen, und mindestens einem Antioxidans sowie Zubereitungen mit einem Gehalt an solchen Wirkstoffkombinationen |
| ID24710A (id) * | 1998-05-12 | 2000-08-03 | Nutricia Nv | Komposisi nutrisi untuk perawatan luka karena tekanan |
| IT1299191B1 (it) * | 1998-06-23 | 2000-02-29 | Sigma Tau Healthscience Spa | Composizione atta a prevenire e trattare l'osteoporosi e le alterazioni legate alla menopausa |
-
1998
- 1998-11-13 IT IT1998RM000706A patent/IT1302863B1/it active IP Right Grant
-
1999
- 1999-11-04 AR ARP990105588A patent/AR021089A1/es unknown
- 1999-11-05 ES ES99956311T patent/ES2249039T3/es not_active Expired - Lifetime
- 1999-11-05 DE DE69927701T patent/DE69927701T2/de not_active Expired - Lifetime
- 1999-11-05 TR TR2001/01344T patent/TR200101344T2/tr unknown
- 1999-11-05 AT AT99956311T patent/ATE306258T1/de active
- 1999-11-05 SK SK616-2001A patent/SK6162001A3/sk unknown
- 1999-11-05 PL PL348515A patent/PL201896B1/pl unknown
- 1999-11-05 WO PCT/IT1999/000351 patent/WO2000028986A1/en not_active Ceased
- 1999-11-05 EP EP99956311A patent/EP1128822B1/en not_active Expired - Lifetime
- 1999-11-05 DK DK99956311T patent/DK1128822T3/da active
- 1999-11-05 AU AU12941/00A patent/AU766402B2/en not_active Ceased
- 1999-11-05 CA CA002350220A patent/CA2350220C/en not_active Expired - Fee Related
- 1999-11-05 HU HU0104347A patent/HU229061B1/hu not_active IP Right Cessation
- 1999-11-05 CZ CZ20011609A patent/CZ20011609A3/cs unknown
- 1999-11-05 IL IL14300199A patent/IL143001A0/xx unknown
- 1999-11-09 MA MA25841A patent/MA25592A1/fr unknown
- 1999-11-11 TN TNTNSN99212A patent/TNSN99212A1/fr unknown
-
2001
- 2001-05-11 NO NO20012338A patent/NO20012338L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TNSN99212A1 (fr) | 2005-11-10 |
| DE69927701D1 (de) | 2006-02-23 |
| CZ20011609A3 (cs) | 2002-01-16 |
| NO20012338D0 (no) | 2001-05-11 |
| DK1128822T3 (da) | 2006-02-06 |
| ITRM980706A1 (it) | 2000-05-13 |
| NO20012338L (no) | 2001-05-11 |
| IT1302863B1 (it) | 2000-10-10 |
| HUP0104347A2 (hu) | 2002-04-29 |
| MA25592A1 (fr) | 2002-12-31 |
| HUP0104347A3 (en) | 2003-01-28 |
| HU229061B1 (hu) | 2013-07-29 |
| AR021089A1 (es) | 2002-06-12 |
| AU1294100A (en) | 2000-06-05 |
| CA2350220C (en) | 2008-06-17 |
| EP1128822B1 (en) | 2005-10-12 |
| IL143001A0 (en) | 2002-04-21 |
| CA2350220A1 (en) | 2000-05-25 |
| ITRM980706A0 (it) | 1998-11-13 |
| DE69927701T2 (de) | 2006-07-20 |
| SK6162001A3 (en) | 2001-10-08 |
| WO2000028986A1 (en) | 2000-05-25 |
| EP1128822A1 (en) | 2001-09-05 |
| PL201896B1 (pl) | 2009-05-29 |
| ES2249039T3 (es) | 2006-03-16 |
| PL348515A1 (en) | 2002-06-03 |
| AU766402B2 (en) | 2003-10-16 |
| ATE306258T1 (de) | 2005-10-15 |
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