TR200102985T2 - Gen tedavisi teknikleri. - Google Patents

Gen tedavisi teknikleri.

Info

Publication number
TR200102985T2
TR200102985T2 TR2001/02985T TR200102985T TR200102985T2 TR 200102985 T2 TR200102985 T2 TR 200102985T2 TR 2001/02985 T TR2001/02985 T TR 2001/02985T TR 200102985 T TR200102985 T TR 200102985T TR 200102985 T2 TR200102985 T2 TR 200102985T2
Authority
TR
Turkey
Prior art keywords
gene therapy
egr
wounds
nucleic acid
treatment
Prior art date
Application number
TR2001/02985T
Other languages
English (en)
Inventor
Braddock Martin
Jeffrey Campbell Callum
Schwachtgen Jean-Lue
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9811836.7A external-priority patent/GB9811836D0/en
Priority claimed from GBGB9815035.2A external-priority patent/GB9815035D0/en
Priority claimed from GBGB9819846.8A external-priority patent/GB9819846D0/en
Priority claimed from GBGB9828578.6A external-priority patent/GB9828578D0/en
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of TR200102985T2 publication Critical patent/TR200102985T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Bulus, insanlar dahil bir memelide yaralarin tedavisi için bir ilacin üretiminde, bir Egr-1 transkripsiyon faktörü polipeptidinin veya bunun biyolojik olarak aktif bir fregmaninin kullanimi ile, bu tip polipeptitleri sifreleyen nükleikasit molekülleri ile ilgilidir. Ek olarak, bulus, insanlarda Egr-1 transkripsiyon fakktörünün transkripsiyonunda ve bunun düzenlenmesinde yer alan önemli bölgeleri içerdigi kabul edilen bir dizi ilgilidir. Bu dizi yaralarin tedavisnde, ve ayni zamanda diger tedavilerde kullanilabilen uygun nükleik asit moleküllerini ve vektörlerini tasarlamak için kullanilabilir.
TR2001/02985T 1998-06-02 1999-06-02 Gen tedavisi teknikleri. TR200102985T2 (tr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9811836.7A GB9811836D0 (en) 1998-06-02 1998-06-02 Gene therapy method
GBGB9815035.2A GB9815035D0 (en) 1998-07-11 1998-07-11 Gene therapy method
GBGB9819846.8A GB9819846D0 (en) 1998-09-12 1998-09-12 Gene therapy method
GBGB9828578.6A GB9828578D0 (en) 1998-12-23 1998-12-23 Regulation

Publications (1)

Publication Number Publication Date
TR200102985T2 true TR200102985T2 (tr) 2002-06-21

Family

ID=27451790

Family Applications (2)

Application Number Title Priority Date Filing Date
TR2001/00348T TR200100348T2 (tr) 1998-06-02 1999-06-02 Gen tedavisi teknikleri
TR2001/02985T TR200102985T2 (tr) 1998-06-02 1999-06-02 Gen tedavisi teknikleri.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TR2001/00348T TR200100348T2 (tr) 1998-06-02 1999-06-02 Gen tedavisi teknikleri

Country Status (28)

Country Link
US (1) US6689758B1 (tr)
EP (2) EP1281763A3 (tr)
JP (1) JP2002516676A (tr)
KR (1) KR20010043968A (tr)
CN (1) CN1311822A (tr)
AP (1) AP2000001999A0 (tr)
AT (1) ATE246518T1 (tr)
AU (1) AU770497B2 (tr)
BR (1) BR9910877A (tr)
CA (1) CA2334171A1 (tr)
DE (1) DE69910202T2 (tr)
DK (1) DK1083934T3 (tr)
EA (1) EA200001124A1 (tr)
EE (1) EE200000790A (tr)
ES (1) ES2205830T3 (tr)
HR (1) HRP20000832A2 (tr)
HU (1) HUP0103252A3 (tr)
ID (1) ID27483A (tr)
IL (1) IL139936A0 (tr)
IS (1) IS5742A (tr)
NO (1) NO20006047L (tr)
NZ (1) NZ508505A (tr)
PL (1) PL345207A1 (tr)
PT (1) PT1083934E (tr)
SK (1) SK18322000A3 (tr)
TR (2) TR200100348T2 (tr)
WO (1) WO1999062561A2 (tr)
YU (1) YU75600A (tr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9928430D0 (en) * 1999-12-01 2000-01-26 Glaxo Group Ltd Screening
EP1467207B1 (en) * 2002-01-10 2008-06-04 Takeda Pharmaceutical Company Limited Screening method for a prophylactic and therapeutic substance for a renal disease.
CA2511315A1 (en) * 2002-12-31 2004-07-22 The Johns Hopkins University Wound healing method and kits
US20070293447A1 (en) * 2003-08-29 2007-12-20 Yasuo Kunugiza Gene Therapy for Skin Disorders Using Needleless Syringes
DE10342071B4 (de) * 2003-09-10 2006-01-19 Fleischmann, Wilhelm, Dr.med. Vorrichtung und Verfahren zur Applikation von Wïrkstoffen an eine Wundoberfläche
KR100647490B1 (ko) 2004-10-04 2006-11-23 사회복지법인 삼성생명공익재단 저산소 조건 및 다른 스트레스에 특이적으로 반응할 수있는 키메라 인핸서 요소를 포함하는 벡터, 상기 벡터를포함하는 약제학적 조성물 및 상기 조성물을 이용하는 방법
EP3199635B1 (en) 2007-05-11 2019-02-06 Adynxx, Inc. Gene expression and pain
FR2920158B1 (fr) * 2007-08-24 2010-03-12 Centre Nat Rech Scient Production de plasmides et expression de proteines recombinantes dans des cellules cultivees sans antibiotiques
FR2924128A1 (fr) * 2007-11-26 2009-05-29 Galderma Res & Dev Modulateurs de egr1 dans le traitement de l'alopecie
US9132202B2 (en) 2009-07-17 2015-09-15 Aaron T. Tabor Compositions and methods for genetic modification of cells having cosmetic function to enhance cosmetic appearance
CN102552938A (zh) * 2012-03-22 2012-07-11 南京大学 Egr-1拮抗剂在制备治疗Ⅱ型糖尿病的药物中的用途
CN104487096B (zh) 2012-05-10 2020-09-15 埃迪恩克斯股份有限公司 用于活性成分递送的配制物
AU2015301491A1 (en) 2014-08-15 2017-02-02 Adynxx, Inc. Oligonucleotide decoys for the treatment of pain
KR101721228B1 (ko) * 2015-04-03 2017-03-30 사회복지법인 삼성생명공익재단 지방유래 줄기세포의 배양액을 유효성분으로 포함하는 발모촉진용 조성물
CN104857529A (zh) * 2015-05-20 2015-08-26 山西大学 Egr-1基因在制备抗膀胱癌药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206152A (en) * 1988-04-08 1993-04-27 Arch Development Corporation Cloning and expression of early growth regulatory protein genes
US5763209A (en) * 1988-09-26 1998-06-09 Arch Development Corporation Methods and materials relating to the functional domains of DNA binding proteins
AUPN855496A0 (en) * 1996-03-07 1996-04-04 Unisearch Limited Prevention of proliferation of vascular cells

Also Published As

Publication number Publication date
JP2002516676A (ja) 2002-06-11
AU4156099A (en) 1999-12-20
HK1034465A1 (en) 2001-10-26
HUP0103252A3 (en) 2003-09-29
BR9910877A (pt) 2002-01-22
IL139936A0 (en) 2002-02-10
ES2205830T3 (es) 2004-05-01
TR200100348T2 (tr) 2001-07-23
DK1083934T3 (da) 2003-12-01
IS5742A (is) 2000-11-28
DE69910202T2 (de) 2004-06-17
SK18322000A3 (sk) 2001-11-06
EP1281763A3 (en) 2003-07-09
WO1999062561A2 (en) 1999-12-09
WO1999062561A3 (en) 2000-08-03
CN1311822A (zh) 2001-09-05
AU770497B2 (en) 2004-02-26
DE69910202D1 (de) 2003-09-11
ATE246518T1 (de) 2003-08-15
US6689758B1 (en) 2004-02-10
EP1281763A2 (en) 2003-02-05
YU75600A (sh) 2004-03-12
EA200001124A1 (ru) 2001-08-27
ID27483A (id) 2001-04-12
EP1083934B1 (en) 2003-08-06
PT1083934E (pt) 2003-12-31
HRP20000832A2 (en) 2001-04-30
CA2334171A1 (en) 1999-12-09
HUP0103252A2 (hu) 2001-12-28
NZ508505A (en) 2003-04-29
PL345207A1 (en) 2001-12-03
EP1083934A2 (en) 2001-03-21
KR20010043968A (ko) 2001-05-25
NO20006047D0 (no) 2000-11-29
NO20006047L (no) 2001-02-01
EE200000790A (et) 2002-04-15
AP2000001999A0 (en) 2000-12-31

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