TR200103188T2 - Sıvı ve katı lipit karışımları temelli lipid parçacıklar. - Google Patents

Sıvı ve katı lipit karışımları temelli lipid parçacıklar.

Info

Publication number
TR200103188T2
TR200103188T2 TR2001/03188T TR200103188T TR200103188T2 TR 200103188 T2 TR200103188 T2 TR 200103188T2 TR 2001/03188 T TR2001/03188 T TR 2001/03188T TR 200103188 T TR200103188 T TR 200103188T TR 200103188 T2 TR200103188 T2 TR 200103188T2
Authority
TR
Turkey
Prior art keywords
lipid
solid
liquid
particles
particle dispersions
Prior art date
Application number
TR2001/03188T
Other languages
English (en)
Inventor
Helmut Müller Rainer
Jenning Volkhard
Mader Karsten
Lippacher Andreas
Original Assignee
Pharmasol Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1999138371 external-priority patent/DE19938371A1/de
Priority claimed from DE19945203A external-priority patent/DE19945203A1/de
Application filed by Pharmasol Gmbh filed Critical Pharmasol Gmbh
Publication of TR200103188T2 publication Critical patent/TR200103188T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Cosmetics (AREA)
  • Colloid Chemistry (AREA)

Abstract

Bulus, kati ve sivi lipidlerden yapilmis karisik bir matriksin ilaçsiz ya da ilaç yüklü lipid parçaciklari ile ve % 30'dan % 95'e kadar degisen bir lipid içerigine ya da % 30'dan % 95'e kadar degisen bir kati madde (lipid ve dengeleyici) içerigine sahip olan kati-sivi parçaciklarin çok yogun lipid parçacigi dispersiyonlarinin bir üretim yöntemiyle ilgilidir ki, biamfifilik kremlerin aksine tamamlayici parçaciklardir ve/veya da çok yogun parçacik dispersiyonlarinin dis fazla seyreltilmeleri üzerine serbest akan parçacik dispersiyonlari meydana gelir.
TR2001/03188T 1999-05-07 2000-05-08 Sıvı ve katı lipit karışımları temelli lipid parçacıklar. TR200103188T2 (tr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19921034 1999-05-07
DE1999138371 DE19938371A1 (de) 1999-08-09 1999-08-09 Zusammensetzung, Herstellung und Verwendung einer Suspension verfestigter, amorpher Öltröpfchen
DE19945203A DE19945203A1 (de) 1999-05-07 1999-09-21 Fest-flüssig (halbfeste) Lipidpartikel (Nano-Compartiment-Carrier-NCC) und Verfahren zur Herstellung hochkonzentrierter Lipidpartikel
DE10016357 2000-03-31

Publications (1)

Publication Number Publication Date
TR200103188T2 true TR200103188T2 (tr) 2002-04-22

Family

ID=27437798

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03188T TR200103188T2 (tr) 1999-05-07 2000-05-08 Sıvı ve katı lipit karışımları temelli lipid parçacıklar.

Country Status (8)

Country Link
EP (1) EP1176949B1 (tr)
JP (1) JP2002544155A (tr)
AU (1) AU4917900A (tr)
BR (1) BR0010354A (tr)
CA (1) CA2369594A1 (tr)
MX (1) MXPA01011343A (tr)
TR (1) TR200103188T2 (tr)
WO (1) WO2000067728A2 (tr)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4672140B2 (ja) 1998-03-12 2011-04-20 ザ プロクター アンド ギャンブル カンパニー 酵素インヒビターを含有するスキンケア組成物を有する使い捨て吸収性製品
US6814959B1 (en) 1999-07-13 2004-11-09 Pharmasol Gmbh UV radiation reflecting or absorbing agents, protecting against harmful UV radiation and reinforcing the natural skin barrier
WO2001043717A1 (en) * 1999-12-17 2001-06-21 The Procter & Gamble Company Compositions for efficient release of active ingredients
ATE381327T1 (de) * 2000-05-12 2008-01-15 Meracol Corp Ltd Cethylmyristat und cetylpalmitat zurbehandlung von ekzemen und/oder psoriasis
US20030153620A1 (en) 2000-05-12 2003-08-14 Meakin Timothy David Treating eczema and/or psoriasis
NZ504526A (en) * 2000-05-12 2003-05-30 Meracol Corp Ltd Treating herpes simplex symptoms using a mixture of cetyl myristate and cetyl palmitate
DE60132444T2 (de) 2000-05-12 2009-01-22 Meracol Corp. Ltd., Takapuna Behandlung von reizkolon-syndrom oder -krankheit
DE10065217A1 (de) * 2000-12-27 2002-07-18 Pharmasol Gmbh Transfektionskomplexe (TransoPlex) mit reduzierter Toxizität, hoher physikalischer Stabilität und hoher Transfektionseffizienz sowie Verfahren zu ihrer Herstellung
DE10228680A1 (de) * 2002-06-27 2004-01-22 Holden Development Limited, Tortola Grundlage für transdermale Formulierungen (PTF)
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
FR2852843B1 (fr) 2003-03-24 2008-05-23 Karim Ioualalen Systeme galenique permettant le masquage du gout
US20040191207A1 (en) * 2003-03-31 2004-09-30 Lipari John M. Alpha-hydroxy acid ester drug delivery compositions and methods of use
BR0318298A (pt) 2003-05-07 2006-07-11 Ifac Gmbh & Co Kg composições para a liberação dirigida de fragráncias e aromas
JP2007503418A (ja) 2003-08-27 2007-02-22 バイヤースドルフ・アクチエンゲゼルシヤフト 局所使用中に個別には感知不能になる外皮を有するカプセル
US8741320B2 (en) 2003-08-27 2014-06-03 Beiersdorf Ag Spherical cosmetic preparations for topical application
DE10357640A1 (de) 2003-08-27 2005-03-24 Beiersdorf Ag Kosmetische kugelförmige Zubereitungen zur topischen Anwendung
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
CA2670821C (en) 2006-08-09 2012-05-15 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
CA2669392C (en) 2006-11-17 2016-05-10 Abbott Gmbh & Co. Kg Nanocrystals for use in topical cosmetic formulations and method of production thereof
CA2683610C (en) 2007-04-23 2013-01-08 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
DE102007055341A1 (de) 2007-11-19 2009-05-20 Bayer Animal Health Gmbh Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren
WO2009102467A2 (en) 2008-02-13 2009-08-20 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
EP2229936B1 (en) * 2009-03-09 2015-05-06 PharmaSol GmbH Nanonized testosterone formulations for improved bioavailability
MX378797B (es) 2009-09-28 2025-03-10 Intarcia Therapeutics Inc Establecimiento y/o terminacion rapidos de suministro de estado estable sustancial de farmaco.
ES2384060B1 (es) 2010-03-24 2013-09-23 Lipotec S.A. Cápsulas de nanopartículas lipídicas.
EP2441441A1 (en) * 2010-10-14 2012-04-18 Deva Holding Anonim Sirketi A sieving method for cetyl myristate and/or cetyl palmitate
US8895536B2 (en) 2010-10-29 2014-11-25 Infirst Healthcare Ltd. Compositions and methods for treating chronic inflammation and inflammatory diseases
US9308213B2 (en) 2010-10-29 2016-04-12 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US9504664B2 (en) 2010-10-29 2016-11-29 Infirst Healthcare Limited Compositions and methods for treating severe pain
US11730709B2 (en) 2010-10-29 2023-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US11202831B2 (en) 2010-10-29 2021-12-21 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US9744132B2 (en) 2010-10-29 2017-08-29 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US10695431B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US11224659B2 (en) 2010-10-29 2022-01-18 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US9737500B2 (en) 2010-10-29 2017-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US9271950B2 (en) 2010-10-29 2016-03-01 Infirst Healthcare Limited Compositions for treating chronic inflammation and inflammatory diseases
US10695432B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in severe pain
GB201021937D0 (en) * 2010-12-24 2011-02-02 Reckitt & Colman Overseas Skin sanitizer compositions comprising alcohol based emulsion
EA024947B1 (ru) * 2010-12-28 2016-11-30 Юнилевер Нв Способ получения эмульсии
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
KR20140031227A (ko) * 2011-03-24 2014-03-12 레오 파마 에이/에스 지질 나노입자들 및 코르티코스테로이드 또는 비타민 ｄ 유도체를 포함하는 조성물
EP2760433B1 (en) 2011-09-29 2023-05-31 PLx Opco Inc. pH DEPENDENT CARRIERS FOR TARGETED RELEASE OF PHARMACEUTICALS ALONG THE GASTROINTESTINAL TRACT, COMPOSITIONS THEREFROM, AND MAKING AND USING SAME
CN102688152A (zh) * 2012-06-05 2012-09-26 东南大学 复合防晒剂纳米结构脂质载体及其制备方法
RU2677346C2 (ru) * 2013-01-14 2019-01-16 ИнФерст Хэлткэр Лимитед Композиции и способы для лечения сильной боли
CN105007947B (zh) * 2013-01-14 2019-02-15 因佛斯特医疗有限公司 固溶体组合物及其在心血管疾病中的用途
KR20150129664A (ko) * 2013-02-04 2015-11-20 인퍼스트 헬스케어 리미티드 만성 염증 및 염증성 질병을 치료하기 위한 조성물 및 방법
DE102013224627A1 (de) 2013-11-29 2015-06-03 Andreas Lauterbach Pharmazeutische Formulierung mit Lipidmikropartikeln und Herstellungsverfahren
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
WO2017054071A1 (en) * 2015-01-21 2017-04-06 Willinsky Michael Composition and methods to improve stability, dosing, pharmacodynamics and product shelf life of endocannabinoids, phytocannabinoids and synthetic cannabinoids delivered by nasal inhaler
CN113598842A (zh) 2015-06-03 2021-11-05 因塔西亚制药公司 植入物放置和移除系统
EP3228359A1 (en) * 2016-04-06 2017-10-11 Infinitec Activos, S.L. Chlorella compositions and use therof for reducing dark circles under the eyes
KR102574993B1 (ko) 2016-05-16 2023-09-06 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
WO2018129058A1 (en) 2017-01-03 2018-07-12 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a glp-1 receptor agonist and co-adminstration of a drug
JP6908769B2 (ja) 2017-03-15 2021-07-28 セレシン・インコーポレーテッド 高い薬物充填量の中鎖脂肪酸トリグリセリドを有する医薬組成物およびそれに関連する方法
CN112566629B (zh) 2018-03-15 2023-11-17 睿升公司 具有高药物装载的中链甘油三酯的药物组合物及其相关方法
KR102037354B1 (ko) 2018-12-07 2019-10-28 (주) 바이노텍 생리활성물질 봉입을 위한 나노지질전달체 및 이의 제조방법
EP4054348B1 (en) * 2019-12-10 2026-01-28 Lonza Sales AG Particles containing a lipid matrix core and active ingredient
JP2023518822A (ja) 2020-03-26 2023-05-08 ピーエルエックス オプコ インコーポレイテッド ｐＨ依存的再構築が可能な医薬キャリア、その製造方法及び使用方法
DE102023103292A1 (de) * 2023-02-10 2024-08-14 Cineolux Gmbh Dispersion und Zubereitung zur topischen Anwendung
CN116406663A (zh) * 2023-04-11 2023-07-11 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 一种含草蒿脑的果蝇驱避剂及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5213810A (en) * 1990-03-30 1993-05-25 American Cyanamid Company Stable compositions for parenteral administration and method of making same
DE69208765T2 (de) * 1991-07-23 1996-09-26 American Cyanamid Co Stabile Zusammensetzungen für parenterale Verabrechung und ihre Verwendung
US5250236A (en) * 1991-08-05 1993-10-05 Gasco Maria R Method for producing solid lipid microspheres having a narrow size distribution
JPH08505367A (ja) * 1992-10-16 1996-06-11 スミスクライン・ビーチャム・コーポレイション 医薬用エマルジョン組成物
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
JP3454385B2 (ja) * 1993-10-15 2003-10-06 啓次郎 佐藤 Ｏ／ｗ型皮膚用クリームの製造方法
US6333021B1 (en) * 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
JPH09151112A (ja) * 1995-11-30 1997-06-10 Noevir Co Ltd 微細エマルション組成物
FR2775441B1 (fr) * 1998-02-27 2000-04-28 Serobiologiques Lab Sa Matrice pour la preparation de microparticules ou de nanoparticules, procede de fabrication de telles particules et particules obtenues

Also Published As

Publication number Publication date
AU4917900A (en) 2000-11-21
JP2002544155A (ja) 2002-12-24
BR0010354A (pt) 2002-03-05
EP1176949B1 (de) 2014-12-10
WO2000067728A2 (de) 2000-11-16
CA2369594A1 (en) 2000-11-16
EP1176949A2 (de) 2002-02-06
MXPA01011343A (es) 2002-06-04
WO2000067728A3 (de) 2001-08-09

Similar Documents

Publication Publication Date Title
BR0010354A (pt) Partìculas de lipìdeo à base em misturas de lipìdeos lìquidos e sólidos e método para a sua produção
Kusukawa et al. Probing guest geometry and dynamics through host-guest interactions this work was supported by the CREST (core research for evolutional science and technology) project of Japan science and technology corporation
Cuevas Arenas et al. Fast collisional lipid transfer among polymer-bounded nanodiscs
Dausend et al. Uptake mechanism of oppositely charged fluorescent nanoparticles in HeLa cells
KR930016091A (ko) 거의 수불용성인 약제의 고체 분산액을 제조하는 방법
TR200200763T2 (tr) Antiviral bileşimler
MY128792A (en) Personal wash compositions containing particle-in-oil dispersion
BR0014087A (pt) Composições com pérolas de caroteno - xantofila estáveis e métodos de uso
MY158857A (en) Immune modulators, preparations and compositions including immune modulators, tests for evaluating the activity of immune modulators and preparation and compositions including the same, and methods
NO990276L (no) Ultralydavbildning av lever
BR9910481A (pt) Composição farmacêutica para comprimido de liberação não-contìnua
DE69911734D1 (de) Stabilisierte ascorbinsäure, zusammensetzung, und verfahren zu ihrer verwendung
EA200601588A1 (ru) Стабилизированные перенасыщенные твёрдые растворы липофильных лекарственных средств
Chandrabhas et al. Nucleotide‐Selective Templated Self‐Assembly of Nanoreactors under Dissipative Conditions
TR200001023T2 (tr) Alfa-aril-N-Alkilnitronlar ve onları içeren farmasötik kompozisyonlar.
Mondal et al. Dual self-sorting by cucurbit [8] uril to transform a mixed micelle to vesicle
WO1999007728A3 (fr) Peptides lineaires derives de peptides antibiotiques, leur preparation et leur utilisation pour vectoriser des substances actives
TR200401219T4 (tr) Mikron ve alt partikül oluşturmak için aparat ve yöntem.
TR200402067T4 (tr) 1,3-Dihidro-2H-İndol-2-One türevleri ve bunların arjinin-vasopresin alıcılarının V1B veya V1B ve V1A ligandları olarak kullanımları
Goloub et al. Association behavior of ampholytic diblock copolymers
TR200101417T2 (tr) Sefuroksim aksetil içeren kompozisyonlar.
Marín-García et al. Low-toxicity metallosomes for biomedical applications by self-assembly of organometallic metallosurfactants and phospholipids
Ježek et al. Fatty acid binding site of the mitochondrial uncoupling protein: Demonstration of its existence by EPR spectroscopy of 5-DOXYL-stearic acid
Uekaji et al. Micelle formation of coenzyme Q10 with dipotassium glycyrrhizate using inclusion complex of coenzyme Q10 with γ-cyclodextrin
Ghosh et al. A peptide derived from a conserved domain of sendai virus fusion protein inhibits virus-cell fusion: a plausible mode of action