TR200103594T2 - Kısa tesirli bir hipnotik veya bunun bir tuzunu içeren zaman ayarlı çift salımlı dozaj formları - Google Patents

Kısa tesirli bir hipnotik veya bunun bir tuzunu içeren zaman ayarlı çift salımlı dozaj formları

Info

Publication number
TR200103594T2
TR200103594T2 TR2001/03594T TR200103594T TR200103594T2 TR 200103594 T2 TR200103594 T2 TR 200103594T2 TR 2001/03594 T TR2001/03594 T TR 2001/03594T TR 200103594 T TR200103594 T TR 200103594T TR 200103594 T2 TR200103594 T2 TR 200103594T2
Authority
TR
Turkey
Prior art keywords
short
dosage forms
release dosage
salt
forms containing
Prior art date
Application number
TR2001/03594T
Other languages
English (en)
Inventor
Alaux Gerard
Andre Frederic
Ducassou Jean
Lewis Gareth
Original Assignee
Sanofi-Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8242028&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200103594(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo
Publication of TR200103594T2 publication Critical patent/TR200103594T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Mevcut bulus; bir çözünme profiline göre belirlenmis bir zaman boyunca salinmaya adapte edilen kisa süreli etki eden hipnotikler veya bunlarin tuzlarini içeren, zaman ayarli çift salimli dozaj formlarini saglamakta olup, ilki ani olan (30 dakikaya kadar sona eren) ve ikincisi ise, belirli bir zamana (50 ve 2100 dakikaya) geciktirilen iki salim pulsunu içermesiyle karakterize edilmektedir.
TR2001/03594T 1999-06-28 2000-06-27 Kısa tesirli bir hipnotik veya bunun bir tuzunu içeren zaman ayarlı çift salımlı dozaj formları TR200103594T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99401605A EP1064937A1 (en) 1999-06-28 1999-06-28 Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof

Publications (1)

Publication Number Publication Date
TR200103594T2 true TR200103594T2 (tr) 2002-06-21

Family

ID=8242028

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03594T TR200103594T2 (tr) 1999-06-28 2000-06-27 Kısa tesirli bir hipnotik veya bunun bir tuzunu içeren zaman ayarlı çift salımlı dozaj formları

Country Status (28)

Country Link
EP (2) EP1064937A1 (tr)
JP (1) JP2003503340A (tr)
KR (1) KR20020015064A (tr)
CN (1) CN100415216C (tr)
AR (1) AR024491A1 (tr)
AT (1) ATE269062T1 (tr)
AU (1) AU782162B2 (tr)
BR (1) BR0011994A (tr)
CA (1) CA2370556C (tr)
CO (1) CO5190680A1 (tr)
CZ (1) CZ20014640A3 (tr)
DE (1) DE60011617T2 (tr)
DK (1) DK1194132T3 (tr)
ES (1) ES2222223T3 (tr)
HK (1) HK1043057B (tr)
HU (1) HU227810B1 (tr)
IL (1) IL146928A0 (tr)
MX (1) MXPA01013212A (tr)
NO (1) NO20016283L (tr)
NZ (1) NZ515997A (tr)
PL (1) PL201777B1 (tr)
PT (1) PT1194132E (tr)
SI (1) SI1194132T1 (tr)
SK (1) SK285347B6 (tr)
TR (1) TR200103594T2 (tr)
TW (1) TWI285118B (tr)
WO (1) WO2001000181A2 (tr)
ZA (1) ZA200110005B (tr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1064938A1 (en) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmaceutical dosage forms for controlled release producing at least a timed pulse
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
ATE241968T1 (de) * 1999-08-26 2003-06-15 Neurocrine Biosciences Inc Sedativ hypnotische zusammensetzungen mit gesteuerter freisetzung und diesbezügliche verfahren
US7811557B1 (en) * 2000-10-27 2010-10-12 Viacell, Inc. Methods for improving central nervous system functioning
AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
JP2005515966A (ja) 2001-07-06 2005-06-02 エンドー ファーマシューティカルズ， インコーポレイティド 鎮痛薬としての使用のための６−ヒドロキシ−オキシモルホンの経口投与
DE60223254T2 (de) 2001-07-06 2008-08-14 Penwest Pharmaceuticals Co. Verzögert freisetzende formulierungen von oxymorphon
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
CN1606434A (zh) * 2001-12-19 2005-04-13 株式会社三和化学研究所 控制释放成型品
US20030165566A1 (en) * 2002-01-10 2003-09-04 O'toole Edel Sedative non-benzodiazepine formulations
EP1941878A1 (en) * 2002-01-10 2008-07-09 Biovail Laboratories International Srl Sedative non-benzodiazepine formulations
EP1469848B1 (en) * 2002-01-10 2008-03-19 Biovail Laboratories International Srl Sedative non-benzodiazepine formulations
JP2006506461A (ja) * 2002-10-25 2006-02-23 コルジウム ファーマシューティカル， インコーポレイテッド ミルナシプランのパルス型放出組成物
JP4681843B2 (ja) * 2004-09-30 2011-05-11 日本臓器製薬株式会社 固形医薬製剤
GB0423964D0 (en) * 2004-10-28 2004-12-01 Jagotec Ag Dosage form
FR2887455B1 (fr) * 2005-06-28 2007-08-10 Sanofi Aventis Sa Formulation a liberation prolongee de principes actifs de medicaments
ATE438381T1 (de) * 2005-11-18 2009-08-15 Synhton B V Zolpidemtabletten
AR056633A1 (es) * 2005-12-07 2007-10-17 Gador Sa Composiciones farmaceuticas de agentes hipnoticos de accion corta en forma de liberacion modificada y los procedimientos para preparar dichas formulaciones
US8309104B2 (en) * 2006-03-02 2012-11-13 Watson Pharmaceuticals, Inc. Oral controlled release formulation for sedative and hypnotic agents
KR20070091960A (ko) * 2006-03-08 2007-09-12 주식회사종근당 졸피뎀 또는 그의 염을 포함하는 안전한 제어방출형 제제조성물
HUE029173T2 (hu) 2006-04-26 2017-02-28 Alphapharm Pty Ltd Szabályozott hatóanyag-leadású készítmények, amelyek tartalmaznak nem bevont diszkrét egység(ek)et és egy késleltetett hatóanyag-leadású mátrixot
AU2013202441B2 (en) * 2006-04-26 2016-02-25 Alphapharm Pty Ltd Controlled release formulations comprising uncoated discrete unit(s) and an extended release matrix
JP5275560B2 (ja) * 2006-10-24 2013-08-28 小林化工株式会社 酒石酸ゾルピデム含有素錠の製造方法
EP1938805A1 (en) * 2006-12-22 2008-07-02 LEK Pharmaceuticals D.D. Monolithic sustained release zolpidem tablets
EP1970056A1 (en) * 2007-03-15 2008-09-17 Polichem S.A. Time-specific delayed/pulsatile release dosage forms
WO2009021127A2 (en) * 2007-08-07 2009-02-12 Neurogen Corporation Controlled released compositions
CN102149369B (zh) 2008-04-18 2016-08-10 因泰克制药有限公司 卡比多巴/左旋多巴胃滞留给药
US20100068266A1 (en) 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo-modifiable multiple-release state final dosage form
CA2745741A1 (en) 2008-12-04 2010-06-10 Intec Pharma Ltd. Zaleplon gastroretentive drug delivery system
RU2384336C1 (ru) * 2009-04-22 2010-03-20 Маргарита Алексеевна Морозова Фармацевтический состав для коррекции психосоматических проявлений
CA2767238A1 (en) * 2009-07-07 2011-01-13 Sunovion Pharmaceuticals Inc. Formulations of 6- (5-chloro-2-pyridyl) - 5- [ (4-methyl-1-piperazinyl) carbonyloxy] - 7-0x0-6, 7- dihydro-5h-phyrrolo [3, 4-b] pyrazine
FR2949062B1 (fr) * 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
GB201003731D0 (en) 2010-03-05 2010-04-21 Univ Strathclyde Immediate/delayed drug delivery
GB201003766D0 (en) * 2010-03-05 2010-04-21 Univ Strathclyde Pulsatile drug release
GB201003734D0 (en) 2010-03-05 2010-04-21 Univ Strathclyde Delayed prolonged drug delivery
FR2968992B1 (fr) * 2010-12-16 2013-02-08 Sanofi Aventis Comprime pharmaceutique orodispersible a base de zolpidem
FR2968995B1 (fr) * 2010-12-16 2013-03-22 Sanofi Aventis Composition pharmaceutioue pour une administration par voie orale destinee a eviter le mesusage
TWI505841B (zh) * 2011-09-29 2015-11-01 Taiwan Biotech Co Ltd 治療睡眠障礙之控釋調配物
CA2934595C (en) * 2014-02-06 2022-06-21 Sequential Medicine Limited Composition and method for aiding sleep
RU2659200C1 (ru) * 2017-07-24 2018-06-28 Общество С Ограниченной Ответственностью "Валента - Интеллект" Фармацевтический состав, содержащий алимемазина тартрат

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8404467D0 (sv) * 1984-09-06 1984-09-06 Ferrosan Ab Controlled-release medical preparations
GB2185887B (en) * 1987-02-18 1989-12-06 Farmitalia Carlo Erba Ltd Temazepam composition
FI894611L (fi) * 1988-09-30 1990-03-31 May & Baker Ltd Granulaera farmaceutiska preparat.
FR2656303B1 (fr) * 1989-12-26 1994-06-10 Parke Davis Solution buvable d'un derive des benzodiazepines et son application pharmacologique.
IE61651B1 (en) * 1990-07-04 1994-11-16 Zambon Spa Programmed release oral solid pharmaceutical dosage form
IT1264517B1 (it) * 1993-05-31 1996-09-24 Ekita Investments Nv Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati
IT1276689B1 (it) * 1995-06-09 1997-11-03 Applied Pharma Res Forma farmaceutica solida ad uso orale
US5837284A (en) * 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
FR2742660B1 (fr) * 1995-12-22 1998-04-03 Ethypharm Lab Prod Ethiques Nouvelles formes de microgranules a liberation prolongee contenant du diltiazem comme principe actif
HRP970493A2 (en) * 1996-09-23 1998-08-31 Wienman E. Phlips Oral delayed immediate release medical formulation and method for preparing the same
BR9802915A (pt) * 1997-09-12 2000-01-11 Oscar Gold Procedimento para formar composições farmaceuticas em pilulas ou granulos substancialmente esfericos, de ação controlada e continuada, contendo como agente ativo o (7-bromo-1,3-diidro-5-(2-piridninilo)-2h-1,4-benzodiazep ina-2(1h)-um)
US6066339A (en) * 1997-10-17 2000-05-23 Elan Corporation, Plc Oral morphine multiparticulate formulation
FR2772615B1 (fr) * 1997-12-23 2002-06-14 Lipha Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
EP1005863A1 (en) * 1998-12-04 2000-06-07 Synthelabo Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof

Also Published As

Publication number Publication date
PL357348A1 (en) 2004-07-26
HUP0201907A3 (en) 2004-05-28
CO5190680A1 (es) 2002-08-29
DE60011617D1 (de) 2004-07-22
SK19112001A3 (sk) 2002-05-09
KR20020015064A (ko) 2002-02-27
ATE269062T1 (de) 2004-07-15
HK1043057A1 (en) 2002-09-06
CA2370556C (en) 2009-09-01
EP1194132B1 (en) 2004-06-16
HU227810B1 (en) 2012-03-28
AU6694400A (en) 2001-01-31
CA2370556A1 (en) 2001-01-04
NZ515997A (en) 2004-03-26
WO2001000181A3 (en) 2001-03-01
SK285347B6 (sk) 2006-11-03
EP1064937A1 (en) 2001-01-03
MXPA01013212A (es) 2002-06-21
NO20016283D0 (no) 2001-12-20
TWI285118B (en) 2007-08-11
CZ20014640A3 (cs) 2002-03-13
WO2001000181A2 (en) 2001-01-04
SI1194132T1 (en) 2004-10-31
EP1194132A2 (en) 2002-04-10
JP2003503340A (ja) 2003-01-28
ES2222223T3 (es) 2005-02-01
HUP0201907A2 (hu) 2002-12-28
IL146928A0 (en) 2002-08-14
BR0011994A (pt) 2002-03-05
ZA200110005B (en) 2003-02-26
NO20016283L (no) 2002-02-27
AR024491A1 (es) 2002-10-02
AU782162B2 (en) 2005-07-07
DE60011617T2 (de) 2005-06-09
PL201777B1 (pl) 2009-05-29
CN1358087A (zh) 2002-07-10
DK1194132T3 (da) 2004-10-11
PT1194132E (pt) 2004-10-29
CN100415216C (zh) 2008-09-03
HK1043057B (en) 2005-02-25

Similar Documents

Publication Publication Date Title
TR200103594T2 (tr) Kısa tesirli bir hipnotik veya bunun bir tuzunu içeren zaman ayarlı çift salımlı dozaj formları
DE69926686D1 (de) Vorrichtung zur Verabreichung von hochkonzentrierten NO Pulsen
BR9906735A (pt) Composição farmacêutica lìquida aquosa
BR9810801B1 (pt) composição lìquida aquosa.
TR200201874T2 (tr) Proteaz inhibitörleri olarak yeni bileşikler ve bileşimler.
PE20010400A1 (es) Formulacion de sal comun y moxifloxacina
FR2794295B1 (fr) Dispositif generateur d'ions
BR0209919A (pt) Composições pesticidas lìquidas estáveis
BR9908467B1 (pt) composiÇço de xampu aquosa.
BR0009721A (pt) Inibidores de tirosina quinase de proteìna cìclica
DK0751129T3 (da) Substituerede dihydrodibenz/b,f/azepiner, fremgangsmåde til fremstilling deraf, deres anvendelse i behandlingen af nogle li
DK199900234U4 (da) Paroxetin-methansulfonat i krystallinsk form, farmaceutisk præparat indeholdende dette og andvendelse af forbindelsen til f
EP1236398A4 (en) MICROBICIDAL COMPOSITIONS
DZ3001A1 (fr) Sel de potassium d'oméprazole-(S).
CL2004000551A1 (es) Compuestos derivados de triazol sustituidos con biarilo, sus sales, bloqueadores del canal de sodio; procedimiento de preparacion; composicion farmaceutica; y su uso en el tratamiento o prevencion del dolor.
FI19991703L (fi) Menetelmä ammoniakkipitoisen vesiliuoksen haihduttamiseksi
IT1231012B (it) Composizione farmaceutica per uso orale contenente nac.
NO981522L (no) Aminosyrederivater, deres fremstilling og anvendelse som endotelinantagonister
EA200200207A1 (ru) Применение антагонистов cgrp и ингибиторов высвобождения cgrp для устранения приливов в период менопаузы
ATE316782T1 (de) Neue orale formulierungen für 5-ht4 agonisten oder antagonisten
DK1098870T3 (da) Nitratsalt af Cetirizin
BR0002667A (pt) Método de preparação de sais de complexo de lìtio para o uso em células eletroquìmicas
EE200300202A (et) Tiotroopiumsoola sisaldav inhaleeritav lahusekompositsioon
ID28729A (id) Metode formulasi garam logam alkali
EE200300203A (et) Tiotroopiumsoola sisaldav inhaleeritav lahusekompositsioon