TR200202104T2 - Mikroorganizmaların etkisiz hale getirilmesi yöntemi. - Google Patents

Mikroorganizmaların etkisiz hale getirilmesi yöntemi.

Info

Publication number
TR200202104T2
TR200202104T2 TR2002/02104T TR200202104T TR200202104T2 TR 200202104 T2 TR200202104 T2 TR 200202104T2 TR 2002/02104 T TR2002/02104 T TR 2002/02104T TR 200202104 T TR200202104 T TR 200202104T TR 200202104 T2 TR200202104 T2 TR 200202104T2
Authority
TR
Turkey
Prior art keywords
microorganism
agent
crosslinking agent
usually
methods
Prior art date
Application number
TR2002/02104T
Other languages
English (en)
Inventor
Johannes Barteling Simon
Original Assignee
Agricultural Research Council
Institute For Animal Science & Health Research
Johannes Barteling Simon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agricultural Research Council, Institute For Animal Science & Health Research, Johannes Barteling Simon filed Critical Agricultural Research Council
Publication of TR200202104T2 publication Critical patent/TR200202104T2/tr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/125Picornaviridae, e.g. calicivirus
    • A61K39/135Foot- and mouth-disease virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32111Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32111Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32161Methods of inactivation or attenuation
    • C12N2770/32163Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Fertilizers (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Bu bulus, bir mikroorganizmanin etkisiz hale getirilmesi ve bir asinin hazirlanmasi için bahsedilen mikroorganizmaya bir çapraz-baglama maddesinin, ayri bir etkisizlestirici madde ile eszamanli olarak tatbik edilmesi basamagini içeren yöntemler saglar. Bu bulus ayrica bu tür yöntemlerle hazirlanan asilara ve etkisiz hale getirilmis mikroorganizmayi içeren bir kite de iliskindir. Çapraz baglama maddesi, genellikle formaldehittir (FA) ve etkisizlestirici madde, genellikle ikili etilenimindir (BEI).
TR2002/02104T 1999-12-20 2000-12-18 Mikroorganizmaların etkisiz hale getirilmesi yöntemi. TR200202104T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ZA997757 1999-12-20

Publications (1)

Publication Number Publication Date
TR200202104T2 true TR200202104T2 (tr) 2002-12-23

Family

ID=25588046

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/02104T TR200202104T2 (tr) 1999-12-20 2000-12-18 Mikroorganizmaların etkisiz hale getirilmesi yöntemi.

Country Status (15)

Country Link
US (1) US6673349B2 (tr)
EP (1) EP1240310B1 (tr)
JP (1) JP2003517834A (tr)
AT (1) ATE384786T1 (tr)
AU (1) AU782907B2 (tr)
BR (1) BR0016563A (tr)
CA (1) CA2394946C (tr)
CY (1) CY1107420T1 (tr)
DE (1) DE60037907T2 (tr)
DK (1) DK1240310T3 (tr)
ES (1) ES2300286T3 (tr)
PT (1) PT1240310E (tr)
PY (1) PY0215294A (tr)
TR (1) TR200202104T2 (tr)
WO (1) WO2001046390A2 (tr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4873632B2 (ja) * 2004-01-21 2012-02-08 メリアル リミテッド 改良された不活化fcvワクチン
KR20110097960A (ko) * 2008-12-19 2011-08-31 가부시끼가이샤 사이와이 메딕스 단백질 가교 고정 시약으로 고정시킨 미생물을 항원으로서 이용하는 망라적 항표면 항체 제조 방법
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
CN102406931B (zh) * 2011-11-25 2014-02-05 成都康华生物制品有限公司 大流行流感病毒裂解疫苗
CN105056225B (zh) * 2015-07-30 2018-01-16 成都天邦生物制品有限公司 一种灭活疫苗的制备方法
CA3010049C (en) * 2016-01-15 2021-10-12 The Chemo-Sero-Therapeutic Research Institute Vaccine containing immobilized virus particles
CN114540317A (zh) * 2022-03-17 2022-05-27 新疆方牧生物科技有限公司 一种悬浮培养口蹄病毒灭活的工艺方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1924303A1 (de) 1969-05-13 1970-12-17 Bayer Ag AEthylaethylenimin als Inaktivierungsmittel
US5069901A (en) * 1988-02-03 1991-12-03 Jones Elaine V Preparation of a recombinant subunit vaccine against pseudorabies infection
US5242686A (en) * 1990-11-07 1993-09-07 American Home Products Corporation Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same
GB9110808D0 (en) * 1991-05-17 1991-07-10 Retroscreen Ltd Aids vaccine and method for its production
KR100374295B1 (ko) * 1993-02-08 2003-12-24 바이엘 코포레이션 돼지생식및호흡증후군바이러스의생육방법과백신에서그의용도
CZ218798A3 (cs) * 1996-02-23 1999-07-14 The Procter & Gamble Company Dezinfekční prostředky

Also Published As

Publication number Publication date
AU782907B2 (en) 2005-09-08
PT1240310E (pt) 2008-05-05
PY0215294A (es) 2004-07-01
JP2003517834A (ja) 2003-06-03
CY1107420T1 (el) 2012-12-19
DE60037907D1 (de) 2008-03-13
BR0016563A (pt) 2002-09-10
US6673349B2 (en) 2004-01-06
CA2394946A1 (en) 2001-06-28
ATE384786T1 (de) 2008-02-15
AU2979601A (en) 2001-07-03
EP1240310B1 (en) 2008-01-23
WO2001046390A2 (en) 2001-06-28
EP1240310A2 (en) 2002-09-18
US20030035811A1 (en) 2003-02-20
DK1240310T3 (da) 2008-05-26
DE60037907T2 (de) 2009-07-09
CA2394946C (en) 2010-12-14
ES2300286T3 (es) 2008-06-16
WO2001046390A3 (en) 2001-12-20

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