TR200401906T4 - Kendini emülsifiye ilaç sistemi, yağ ajanı seçime bağlıdır. - Google Patents
Kendini emülsifiye ilaç sistemi, yağ ajanı seçime bağlıdır.Info
- Publication number
- TR200401906T4 TR200401906T4 TR2004/01906T TR200401906T TR200401906T4 TR 200401906 T4 TR200401906 T4 TR 200401906T4 TR 2004/01906 T TR2004/01906 T TR 2004/01906T TR 200401906 T TR200401906 T TR 200401906T TR 200401906 T4 TR200401906 T4 TR 200401906T4
- Authority
- TR
- Turkey
- Prior art keywords
- pharmaceutical composition
- proton pump
- pump inhibitor
- composition
- optional
- Prior art date
Links
- 239000003795 chemical substances by application Substances 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 3
- 229940126409 proton pump inhibitor Drugs 0.000 abstract 3
- 239000000612 proton pump inhibitor Substances 0.000 abstract 3
- 239000000839 emulsion Substances 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Bu icat agizdan alim için uygun bir emülsiyon ön konsantresi biçiminde olan, (i) bir ya da daha fazla NO açiga çikaran NSAID(ler)'den; (ii) bir yada daha fazla yüzey aktif maddeden;(iii) seçime bagli olarak ek bir sivi ya da yari kati yagdan olusan bir farmasötik bilesim açiklamakta ve isteminde bulunmaktadir ki, sözü edilen bilesim mide-bagirsak sivilariyla temas ettiginde bir yerinde su-içinde-sivi yag emülsiyonu olusturur. Bu bilesim istege bagli olarak bir ya da daha fazla kisa zincirli alkol de içerebilir. Ayrica, icadin kapsami içinde, bir proton pompasi inhibitörü ile yapilan bir kombinasyon da vardir. Bu farmasötik bilesim agri ve inflamasyon tedavisinde yararlidir. Ayrica, icadin kapsami içinde, icatta belirtilen farmasötik bir bilesimin birim dozaj biçiminin bir proton pompasi inhibitörüyle kombinasyon halinde bulundugu ve sözü edilen proton pompasi inhibitörünün enterik kaplamali oldugu bir kit de bulunmaktadir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0000773A SE0000773D0 (sv) | 2000-03-08 | 2000-03-08 | New formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200401906T4 true TR200401906T4 (tr) | 2004-09-21 |
Family
ID=20278739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2004/01906T TR200401906T4 (tr) | 2000-03-08 | 2001-03-06 | Kendini emülsifiye ilaç sistemi, yağ ajanı seçime bağlıdır. |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US20030161846A1 (tr) |
| EP (1) | EP1267832B1 (tr) |
| JP (1) | JP4663197B2 (tr) |
| KR (1) | KR100771317B1 (tr) |
| CN (2) | CN101862453A (tr) |
| AT (1) | ATE268162T1 (tr) |
| AU (2) | AU3787601A (tr) |
| BR (1) | BR0109014A (tr) |
| CA (1) | CA2401498C (tr) |
| CZ (1) | CZ20023005A3 (tr) |
| DE (1) | DE60103627T2 (tr) |
| DK (1) | DK1267832T3 (tr) |
| EE (1) | EE200200500A (tr) |
| ES (1) | ES2220728T3 (tr) |
| HU (1) | HUP0300882A3 (tr) |
| IL (1) | IL151427A0 (tr) |
| IS (1) | IS6539A (tr) |
| MX (1) | MXPA02008657A (tr) |
| MY (1) | MY127237A (tr) |
| NO (1) | NO20024272L (tr) |
| NZ (1) | NZ521009A (tr) |
| PL (1) | PL202683B1 (tr) |
| PT (1) | PT1267832E (tr) |
| RU (1) | RU2270675C9 (tr) |
| SE (1) | SE0000773D0 (tr) |
| SK (1) | SK285982B6 (tr) |
| TR (1) | TR200401906T4 (tr) |
| UA (1) | UA82979C2 (tr) |
| WO (1) | WO2001066088A1 (tr) |
| ZA (1) | ZA200206740B (tr) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6852739B1 (en) | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
| SE0000774D0 (sv) * | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
| IT1319202B1 (it) | 2000-10-12 | 2003-09-26 | Nicox Sa | Farmaci per le malattie a base infiammatoria. |
| US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
| SE0102993D0 (sv) * | 2001-09-07 | 2001-09-07 | Astrazeneca Ab | New self emulsifying drug delivery system |
| SE0200895D0 (sv) * | 2002-03-22 | 2002-03-22 | Astrazeneca Ab | New pharmaceutical composition |
| ITMI20021392A1 (it) * | 2002-06-25 | 2003-12-29 | Nicox Sa | Forme farmaceutiche per la somministrazione orale di farmaci liquidi a temperatura ambiente dotate di migliore biodisponibilita' |
| AU2003247792B2 (en) | 2002-07-03 | 2009-09-24 | Nicox S.A. | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use |
| US7244753B2 (en) | 2002-07-29 | 2007-07-17 | Nitromed, Inc. | Cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| EP1534278A4 (en) * | 2002-08-01 | 2006-09-06 | Nitromed Inc | NITROSED PROTONATE PUMP INHIBITORS, COMPOSITIONS AND USE METHOD |
| FR2845917B1 (fr) * | 2002-10-21 | 2006-07-07 | Negma Gild | Composition pharmaceutique associant le tenatoprazole et un anti-inflammatoire |
| SE0301880D0 (sv) * | 2003-06-25 | 2003-06-25 | Astrazeneca Uk Ltd | New drug delivery composition |
| KR20050034299A (ko) * | 2003-10-09 | 2005-04-14 | 한국유나이티드제약 주식회사 | 아세클로페낙 자가유화에멀젼 및 이를 이용한 연질캅셀제조성물 및 그의 제조방법 |
| AU2006274098B2 (en) | 2005-07-26 | 2012-02-09 | Nicox Science Ireland | Pharmaceutical formulation of nitrooxyderivatives of NSAIDs |
| EP1965774A2 (en) * | 2005-12-30 | 2008-09-10 | Cogentus Pharmaceuticals, Inc. | Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors |
| US9220698B2 (en) | 2008-09-09 | 2015-12-29 | Pozen Inc. | Method for delivering a pharmaceutical composition to patient in need thereof |
| MX2011005643A (es) * | 2008-12-03 | 2011-09-27 | Astellas Deutschland Gmbh | Formas de dosificacion oral de bendamustina. |
| US20100273730A1 (en) * | 2009-04-27 | 2010-10-28 | Innopharmax, Inc. | Self-emulsifying pharmaceutical compositions of hydrophilic drugs and preparation thereof |
| KR20120030106A (ko) | 2009-06-25 | 2012-03-27 | 아스트라제네카 아베 | Nsaid-연관된 궤양의 발생 위험이 있는 환자의 치료 방법 |
| MY154683A (en) * | 2009-07-07 | 2015-07-15 | Boehringer Ingelheim Int | Pharmaceutical composition for a hepatitis c viral protease inhibitor |
| US9717703B2 (en) | 2009-10-16 | 2017-08-01 | Glaxosmithkline Llc | Emulsion and emulsion preconcentrate compositions comprising omega-3 fatty acids and uses thereof are disclosed |
| EP2797600A4 (en) | 2011-12-28 | 2015-09-16 | Pozen Inc | IMPROVED COMPOSITIONS AND METHODS OF DISTRIBUTING OMEPRAZOLE AND ACETYL SALICYLIC ACID |
| CN102614115B (zh) * | 2012-04-26 | 2013-05-15 | 河南中医学院 | 一种双氯芬酸钠自乳化软膏 |
| EP3043648B1 (en) | 2013-08-27 | 2023-09-20 | Vasilios VOUDOURIS | Bendamustine pharmaceutical compositions |
| MY185428A (en) * | 2015-01-21 | 2021-05-19 | Mochida Pharm Co Ltd | Self-emulsifying composition of ?-3 fatty acid |
| MX387217B (es) * | 2015-08-07 | 2025-03-18 | Infirst Healthcare Ltd | Composiciones de solución sólida para aines. |
| CN113440481B (zh) * | 2021-08-13 | 2022-06-14 | 湖南慧泽生物医药科技有限公司 | 伊布替尼的自微乳组合物 |
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-
2000
- 2000-03-08 SE SE0000773A patent/SE0000773D0/xx unknown
-
2001
- 2001-03-06 AT AT01910305T patent/ATE268162T1/de not_active IP Right Cessation
- 2001-03-06 SK SK1257-2002A patent/SK285982B6/sk not_active IP Right Cessation
- 2001-03-06 HU HU0300882A patent/HUP0300882A3/hu unknown
- 2001-03-06 CZ CZ20023005A patent/CZ20023005A3/cs unknown
- 2001-03-06 CN CN201010156308A patent/CN101862453A/zh active Pending
- 2001-03-06 UA UA2002086883A patent/UA82979C2/ru unknown
- 2001-03-06 US US10/220,791 patent/US20030161846A1/en not_active Abandoned
- 2001-03-06 RU RU2002122744/15A patent/RU2270675C9/ru not_active IP Right Cessation
- 2001-03-06 CA CA2401498A patent/CA2401498C/en not_active Expired - Fee Related
- 2001-03-06 PL PL358595A patent/PL202683B1/pl not_active IP Right Cessation
- 2001-03-06 AU AU3787601A patent/AU3787601A/xx active Pending
- 2001-03-06 ES ES01910305T patent/ES2220728T3/es not_active Expired - Lifetime
- 2001-03-06 PT PT01910305T patent/PT1267832E/pt unknown
- 2001-03-06 DK DK01910305T patent/DK1267832T3/da active
- 2001-03-06 AU AU2001237876A patent/AU2001237876B2/en not_active Ceased
- 2001-03-06 NZ NZ521009A patent/NZ521009A/en unknown
- 2001-03-06 EE EEP200200500A patent/EE200200500A/xx unknown
- 2001-03-06 JP JP2001564741A patent/JP4663197B2/ja not_active Expired - Fee Related
- 2001-03-06 BR BR0109014-3A patent/BR0109014A/pt not_active Application Discontinuation
- 2001-03-06 WO PCT/SE2001/000467 patent/WO2001066088A1/en not_active Ceased
- 2001-03-06 KR KR1020027011731A patent/KR100771317B1/ko not_active Expired - Fee Related
- 2001-03-06 TR TR2004/01906T patent/TR200401906T4/tr unknown
- 2001-03-06 DE DE60103627T patent/DE60103627T2/de not_active Expired - Lifetime
- 2001-03-06 IL IL15142701A patent/IL151427A0/xx active IP Right Grant
- 2001-03-06 MX MXPA02008657A patent/MXPA02008657A/es active IP Right Grant
- 2001-03-06 EP EP01910305A patent/EP1267832B1/en not_active Expired - Lifetime
- 2001-03-06 CN CN018061613A patent/CN1416335B/zh not_active Expired - Fee Related
- 2001-03-07 MY MYPI20011045A patent/MY127237A/en unknown
-
2002
- 2002-08-22 ZA ZA200206740A patent/ZA200206740B/en unknown
- 2002-09-03 IS IS6539A patent/IS6539A/is unknown
- 2002-09-06 NO NO20024272A patent/NO20024272L/no not_active Application Discontinuation
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