TR201713470A2 - PRODUCTION METHOD OF PLGA FIBERS USED IN TISSUE SCAFFOLDING AND PLGA FIBER PRODUCED BY THIS METHOD - Google Patents

PRODUCTION METHOD OF PLGA FIBERS USED IN TISSUE SCAFFOLDING AND PLGA FIBER PRODUCED BY THIS METHOD Download PDF

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Publication number
TR201713470A2
TR201713470A2 TR2017/13470A TR201713470A TR201713470A2 TR 201713470 A2 TR201713470 A2 TR 201713470A2 TR 2017/13470 A TR2017/13470 A TR 2017/13470A TR 201713470 A TR201713470 A TR 201713470A TR 201713470 A2 TR201713470 A2 TR 201713470A2
Authority
TR
Turkey
Prior art keywords
plga
fibers used
fiber produced
production method
tissue scaffolding
Prior art date
Application number
TR2017/13470A
Other languages
Turkish (tr)
Inventor
Torun Köse Gamze
Gürel Peközer Görke
Abay Nergi̇s
Original Assignee
Univ Yeditepe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yeditepe filed Critical Univ Yeditepe
Priority to TR2017/13470A priority Critical patent/TR201713470A2/en
Priority to PCT/TR2018/050482 priority patent/WO2019054970A2/en
Publication of TR201713470A2 publication Critical patent/TR201713470A2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Artificial Filaments (AREA)

Abstract

Bu buluş, kritik boyutlu kemik hasarlarının tamiri için doku mühendisliği iskelesi olarak kullanılmak üzere, PLGA (poli(laktik-ko-glikolik asit)) polimerinin ıslak eğirme yöntemiyle şekillendirilmesi ile elde edilen PLGA fiberleri ile ilgilidir. Buluşun amacı, ıslak eğirme yöntemiyle elde edilen ve fibröz yapıda, uzun süreli mekanik destek sağlayabilecek, biyobozunma hızı yavaş olan PLGA fiberleri gerçekleştirmektir.The present invention relates to PLGA fibers obtained by wet spinning a PLGA (poly (lactic-co-glycolic acid)) polymer for use as a tissue engineering scaffold for repairing critical bone damage. The aim of the invention is to produce PLGA fibers with a fibrous structure, which are obtained by wet spinning method, can provide long-term mechanical support and have a slow biodegradation rate.

TR2017/13470A 2017-09-13 2017-09-13 PRODUCTION METHOD OF PLGA FIBERS USED IN TISSUE SCAFFOLDING AND PLGA FIBER PRODUCED BY THIS METHOD TR201713470A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
TR2017/13470A TR201713470A2 (en) 2017-09-13 2017-09-13 PRODUCTION METHOD OF PLGA FIBERS USED IN TISSUE SCAFFOLDING AND PLGA FIBER PRODUCED BY THIS METHOD
PCT/TR2018/050482 WO2019054970A2 (en) 2017-09-13 2018-09-12 Method of producing plga fibers used as tissue scaffolds and the plga fibers produced with this method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2017/13470A TR201713470A2 (en) 2017-09-13 2017-09-13 PRODUCTION METHOD OF PLGA FIBERS USED IN TISSUE SCAFFOLDING AND PLGA FIBER PRODUCED BY THIS METHOD

Publications (1)

Publication Number Publication Date
TR201713470A2 true TR201713470A2 (en) 2019-03-21

Family

ID=65722963

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2017/13470A TR201713470A2 (en) 2017-09-13 2017-09-13 PRODUCTION METHOD OF PLGA FIBERS USED IN TISSUE SCAFFOLDING AND PLGA FIBER PRODUCED BY THIS METHOD

Country Status (2)

Country Link
TR (1) TR201713470A2 (en)
WO (1) WO2019054970A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110540404B (en) * 2019-10-17 2022-06-10 广州润虹医药科技股份有限公司 Calcium phosphate bone cement with hollow through structure, preparation method and application thereof
CN114438607B (en) * 2022-03-15 2025-03-07 北京亿华通科技股份有限公司 An electrospinning device for preparing fiber membranes with uniform thickness
EP4530380A1 (en) * 2022-05-23 2025-04-02 Nagoya Institute Of Technology Method for continuously producing biodegradable fiber material containing inorganic filler particles using wet spinning, and cotton-like bone regeneration material produced with said method
CN120837744B (en) * 2025-09-24 2025-12-23 中国人民解放军国防科技大学 Micro-nano fiber composite biological film based on electrostatic spinning technology and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7531503B2 (en) * 2005-03-11 2009-05-12 Wake Forest University Health Sciences Cell scaffold matrices with incorporated therapeutic agents
CN105297153B (en) * 2015-11-19 2017-12-12 暨南大学 A kind of wet spinning device and wet spinning process of electrostatic auxiliary

Also Published As

Publication number Publication date
WO2019054970A3 (en) 2019-08-08
WO2019054970A2 (en) 2019-03-21

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