TR201713470A2 - Doku i̇skelesi̇ oluşturulmasinda kullanilan plga fi̇berleri̇ni̇n üreti̇m yöntemi̇ ve bu yöntemle üreti̇len plga fi̇berleri̇ - Google Patents

Doku i̇skelesi̇ oluşturulmasinda kullanilan plga fi̇berleri̇ni̇n üreti̇m yöntemi̇ ve bu yöntemle üreti̇len plga fi̇berleri̇ Download PDF

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Publication number
TR201713470A2
TR201713470A2 TR2017/13470A TR201713470A TR201713470A2 TR 201713470 A2 TR201713470 A2 TR 201713470A2 TR 2017/13470 A TR2017/13470 A TR 2017/13470A TR 201713470 A TR201713470 A TR 201713470A TR 201713470 A2 TR201713470 A2 TR 201713470A2
Authority
TR
Turkey
Prior art keywords
plga
fibers used
fiber produced
production method
tissue scaffolding
Prior art date
Application number
TR2017/13470A
Other languages
English (en)
Inventor
Torun Köse Gamze
Gürel Peközer Görke
Abay Nergi̇s
Original Assignee
Univ Yeditepe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yeditepe filed Critical Univ Yeditepe
Priority to TR2017/13470A priority Critical patent/TR201713470A2/tr
Priority to PCT/TR2018/050482 priority patent/WO2019054970A2/en
Publication of TR201713470A2 publication Critical patent/TR201713470A2/tr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials For Medical Uses (AREA)
  • Artificial Filaments (AREA)

Abstract

Bu buluş, kritik boyutlu kemik hasarlarının tamiri için doku mühendisliği iskelesi olarak kullanılmak üzere, PLGA (poli(laktik-ko-glikolik asit)) polimerinin ıslak eğirme yöntemiyle şekillendirilmesi ile elde edilen PLGA fiberleri ile ilgilidir. Buluşun amacı, ıslak eğirme yöntemiyle elde edilen ve fibröz yapıda, uzun süreli mekanik destek sağlayabilecek, biyobozunma hızı yavaş olan PLGA fiberleri gerçekleştirmektir.
TR2017/13470A 2017-09-13 2017-09-13 Doku i̇skelesi̇ oluşturulmasinda kullanilan plga fi̇berleri̇ni̇n üreti̇m yöntemi̇ ve bu yöntemle üreti̇len plga fi̇berleri̇ TR201713470A2 (tr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
TR2017/13470A TR201713470A2 (tr) 2017-09-13 2017-09-13 Doku i̇skelesi̇ oluşturulmasinda kullanilan plga fi̇berleri̇ni̇n üreti̇m yöntemi̇ ve bu yöntemle üreti̇len plga fi̇berleri̇
PCT/TR2018/050482 WO2019054970A2 (en) 2017-09-13 2018-09-12 PROCESS FOR THE PRODUCTION OF PLGA FIBERS AS TISSUE SCAFFOLDING AND THE PLGA FIBERS PRODUCED ACCORDING TO THIS METHOD

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2017/13470A TR201713470A2 (tr) 2017-09-13 2017-09-13 Doku i̇skelesi̇ oluşturulmasinda kullanilan plga fi̇berleri̇ni̇n üreti̇m yöntemi̇ ve bu yöntemle üreti̇len plga fi̇berleri̇

Publications (1)

Publication Number Publication Date
TR201713470A2 true TR201713470A2 (tr) 2019-03-21

Family

ID=65722963

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2017/13470A TR201713470A2 (tr) 2017-09-13 2017-09-13 Doku i̇skelesi̇ oluşturulmasinda kullanilan plga fi̇berleri̇ni̇n üreti̇m yöntemi̇ ve bu yöntemle üreti̇len plga fi̇berleri̇

Country Status (2)

Country Link
TR (1) TR201713470A2 (tr)
WO (1) WO2019054970A2 (tr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110540404B (zh) * 2019-10-17 2022-06-10 广州润虹医药科技股份有限公司 一种具有中空贯通结构的磷酸钙骨水泥、制备方法及其应用
CN114438607B (zh) * 2022-03-15 2025-03-07 北京亿华通科技股份有限公司 一种用于制备均匀厚度纤维膜的静电纺丝装置
EP4530380A1 (en) * 2022-05-23 2025-04-02 Nagoya Institute Of Technology Method for continuously producing biodegradable fiber material containing inorganic filler particles using wet spinning, and cotton-like bone regeneration material produced with said method
CN120837744B (zh) * 2025-09-24 2025-12-23 中国人民解放军国防科技大学 基于静电纺丝技术的微纳米纤维复合生物膜及制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7531503B2 (en) * 2005-03-11 2009-05-12 Wake Forest University Health Sciences Cell scaffold matrices with incorporated therapeutic agents
CN105297153B (zh) * 2015-11-19 2017-12-12 暨南大学 一种静电辅助的湿法纺丝装置及湿法纺丝方法

Also Published As

Publication number Publication date
WO2019054970A2 (en) 2019-03-21
WO2019054970A3 (en) 2019-08-08

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