TR201817009A2 - Bir hücrede telomer uzunluğunun arttırılması. - Google Patents

Bir hücrede telomer uzunluğunun arttırılması. Download PDF

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Publication number
TR201817009A2
TR201817009A2 TR2018/17009A TR201817009A TR201817009A2 TR 201817009 A2 TR201817009 A2 TR 201817009A2 TR 2018/17009 A TR2018/17009 A TR 2018/17009A TR 201817009 A TR201817009 A TR 201817009A TR 201817009 A2 TR201817009 A2 TR 201817009A2
Authority
TR
Turkey
Prior art keywords
uncaria
telomere length
animal
cell
increasing
Prior art date
Application number
TR2018/17009A
Other languages
English (en)
Inventor
C Giampapa Vincent
Crouse Linda
Original Assignee
Optigenex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Optigenex Inc filed Critical Optigenex Inc
Publication of TR201817009A2 publication Critical patent/TR201817009A2/tr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Battery Electrode And Active Subsutance (AREA)

Abstract

Hayvan hücrelerinde telomerlerin uzunluklarının arttırılmasının bir yöntemi, bir hayvana bir Uncaria türünün bir aköz ekstraktı uygulanarak gerçekleştirilir. Hayvan, bir insan olabilir ve Uncaria türü, Uncaria tomentosa olabilir. Yeterli bir zaman periyodu boyunca Uncaria tomentosa?nın bir aköz ekstraktının günlük dozunu alan insan özneler, tedaviden önce alınan bir taban çizgisi ölçümüne göre telomer uzunluğunda bir artış göstermiştir. Ekstrakt, topikal olarak veya sistemik olarak uygulanabilir.
TR2018/17009A 2017-11-30 2018-11-12 Bir hücrede telomer uzunluğunun arttırılması. TR201817009A2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15/827,223 US10098922B1 (en) 2017-11-30 2017-11-30 Increasing telomere length in a cell

Publications (1)

Publication Number Publication Date
TR201817009A2 true TR201817009A2 (tr) 2019-06-21

Family

ID=63762077

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2018/17009A TR201817009A2 (tr) 2017-11-30 2018-11-12 Bir hücrede telomer uzunluğunun arttırılması.

Country Status (13)

Country Link
US (1) US10098922B1 (tr)
EP (1) EP3492093A1 (tr)
JP (1) JP2019099562A (tr)
KR (1) KR20200095495A (tr)
CN (1) CN109847071B (tr)
BR (1) BR102018074717A8 (tr)
CA (1) CA3021111A1 (tr)
IL (1) IL274795B2 (tr)
MX (1) MX2018014226A (tr)
MY (1) MY194907A (tr)
RU (1) RU2714886C1 (tr)
TR (1) TR201817009A2 (tr)
WO (1) WO2019108454A1 (tr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10098922B1 (en) * 2017-11-30 2018-10-16 Optigenex, Inc. Increasing telomere length in a cell
US11883457B1 (en) * 2022-09-06 2024-01-30 Optigenex Inc. Method of enhancing cognition in individuals with at least normal cognition

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5385938B1 (en) 1986-12-23 1997-07-15 Tristrata Inc Method of using glycolic acid for treating wrinkles
US5489508A (en) 1992-05-13 1996-02-06 University Of Texas System Board Of Regents Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
US5741677A (en) 1995-06-07 1998-04-21 Geron Corporation Methods for measuring telomere length
US6039949A (en) * 1997-02-27 2000-03-21 Campamed, Inc. Method of preparation and composition of a water soluble extract of the plant species uncaria
WO1998051302A1 (en) * 1997-05-15 1998-11-19 University Of Washington Composition and methods for treating alzheimer's disease and other amyloidoses
CA2427661C (en) * 2000-11-03 2013-05-28 Proteotech, Inc. Methods of isolating amyloid-inhibiting compounds and use of compounds isolated from uncaria tomentosa and related plants
US6964784B2 (en) * 2002-03-07 2005-11-15 Optigenex, Inc. Method of preparation and composition of a water soluble extract of the bioactive component of the plant species uncaria for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals
CN1809364B (zh) 2003-06-23 2010-06-16 杰龙公司 增加端粒酶活性的组合物和方法
CA2609615A1 (en) * 2005-03-16 2006-09-28 Genetic Health Enterprises (Pty), Ltd. Medicinal compositions of salts, chelates and/or free acids of alpha hydroxyl organic acids and related processes and methods
US8372488B2 (en) * 2006-05-01 2013-02-12 General Electric Company Methods and apparatus for thermal barrier coatings with improved overall thermal insulation characteristics
KR101560844B1 (ko) * 2007-06-04 2015-10-15 벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 트라이-아릴계 화합물 및 이를 포함하는 조성물
US8029830B2 (en) * 2008-04-18 2011-10-04 Nuvocare Health Services Inc. Composition and method for promoting internal health and external appearance
CN102300578A (zh) * 2008-12-01 2011-12-28 延寿有限责任公司 用于改变健康、安康和寿命的方法和组合物
ES2656958T3 (es) * 2011-03-28 2018-03-01 Geron Corporation Medición de la longitud de telómeros en muestras fijadas en formalina, embebidas en parafina (FFPE) por PCR cuantitativa
US8968801B1 (en) * 2011-09-14 2015-03-03 Cellhealth Technologies Ltd. Supplement composition for supporting DNA repair and method of use
US9345733B1 (en) * 2011-09-14 2016-05-24 Cellhealth Technologies Ltd. Supplement composition for supporting telomere maintenance and protection and method of use
US8747915B1 (en) * 2011-09-14 2014-06-10 Vincent C. Giampapa Dietary supplement system for multifunctional anti-aging management and method of use
WO2014100715A2 (en) * 2012-12-21 2014-06-26 Ehrenkranz Joel R L Supplements and monitoring systems for dosing of the supplements
WO2014153356A1 (en) * 2013-03-18 2014-09-25 Life Science Institute, Llc An in vivo intracellular reprogramming composition and method of making and using same
US9968546B2 (en) 2015-11-10 2018-05-15 Vincent C Giampapa Topical composition for skin treatment to reduce lines and wrinkles of the face and body using a dual DNA repair mechanism to address damage caused by aging and ultra-violet induced damage to the skin with combination of skin turgor enhancement compounds
US10098922B1 (en) * 2017-11-30 2018-10-16 Optigenex, Inc. Increasing telomere length in a cell

Also Published As

Publication number Publication date
CN109847071A (zh) 2019-06-07
WO2019108454A1 (en) 2019-06-06
EP3492093A1 (en) 2019-06-05
IL274795B2 (en) 2023-12-01
CA3021111A1 (en) 2019-05-30
BR102018074717A2 (pt) 2019-06-25
BR102018074717A8 (pt) 2023-03-07
KR20200095495A (ko) 2020-08-10
CN109847071B (zh) 2022-07-19
RU2714886C1 (ru) 2020-02-20
JP2019099562A (ja) 2019-06-24
IL274795B1 (en) 2023-08-01
US10098922B1 (en) 2018-10-16
MX2018014226A (es) 2019-10-14
IL274795A (en) 2020-07-30
MY194907A (en) 2022-12-22

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