TR201901497T4 - Alfa-sinüklein ile ilişkili bozukluklar için terapötik ve teşhis yöntemlerinde kullanıma yönelik antikorlar ve aşılar. - Google Patents

Alfa-sinüklein ile ilişkili bozukluklar için terapötik ve teşhis yöntemlerinde kullanıma yönelik antikorlar ve aşılar. Download PDF

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TR201901497T4
TR201901497T4 TR2019/01497T TR201901497T TR201901497T4 TR 201901497 T4 TR201901497 T4 TR 201901497T4 TR 2019/01497 T TR2019/01497 T TR 2019/01497T TR 201901497 T TR201901497 T TR 201901497T TR 201901497 T4 TR201901497 T4 TR 201901497T4
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synuclein
vaccines
antibodies
alpha
therapeutic
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Lannfelt Lars
Bergström Joakim
Ingelsson Martin
Gellerfors Pär
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Bioarctic Ab
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    • A—HUMAN NECESSITIES
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    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A—HUMAN NECESSITIES
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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Abstract

Bir bireyde bir ?-sinüklein ile ilişkili bozukluğun bir başlangıcının geciktirilmesi için veya tedavi edilmesi için bir aşı, bir çözünmez kümelenmiş forma bir ?-sinükleinin stabilize olmayan oligomerinden daha düşük bir formasyon oranına sahip olan izole edilmiş stabilize çözünür bir ?-sinüklein oligomerinin terapötik olarak etkili bir miktarını içermektedir. Bir bireyde bir ?-sinüklein ile ilişkili bozukluğun bir başlangıcının geciktirilmesi için veya tedavi edilmesi için bir antikor, çözünür ?-sinükleini bağlamaktadır. Bir ?-sinüklein ile ilişkili bozukluğun bir başlangıcının geciktirilmesi için, tedavi edilmesi için veya önlenmesi için yöntemler, aşı veya antikoru kullanmaktadır. ?-sinüklein oligomerlerini saptama yöntemleri, antikoru kullanmaktadır.
TR2019/01497T 2008-04-29 2009-04-28 Alfa-sinüklein ile ilişkili bozukluklar için terapötik ve teşhis yöntemlerinde kullanıma yönelik antikorlar ve aşılar. TR201901497T4 (tr)

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US4886508P 2008-04-29 2008-04-29

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US (4) US8809506B2 (tr)
EP (2) EP2282758B1 (tr)
JP (2) JP5747414B2 (tr)
CY (1) CY1121209T1 (tr)
DK (1) DK2282758T3 (tr)
ES (1) ES2709048T3 (tr)
HR (1) HRP20190092T1 (tr)
HU (1) HUE041223T2 (tr)
LT (1) LT2282758T (tr)
PL (1) PL2282758T3 (tr)
PT (1) PT2282758T (tr)
SI (1) SI2282758T1 (tr)
TR (1) TR201901497T4 (tr)
WO (1) WO2009133521A2 (tr)

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US20140335088A1 (en) 2014-11-13
US9315569B2 (en) 2016-04-19
DK2282758T3 (en) 2019-02-25
PT2282758T (pt) 2019-02-12
JP2015057433A (ja) 2015-03-26
CY1121209T1 (el) 2020-05-29
EP2282758A2 (en) 2011-02-16
ES2709048T3 (es) 2019-04-15
PL2282758T3 (pl) 2019-04-30
US8809506B2 (en) 2014-08-19
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WO2009133521A3 (en) 2010-04-01
HUE041223T2 (hu) 2019-05-28
US20200215209A1 (en) 2020-07-09
EP3470079A1 (en) 2019-04-17
JP5747414B2 (ja) 2015-07-15
US20160199522A1 (en) 2016-07-14
HRP20190092T1 (hr) 2019-03-22
WO2009133521A2 (en) 2009-11-05
LT2282758T (lt) 2019-03-12
EP2282758B1 (en) 2018-11-21
SI2282758T1 (sl) 2019-03-29

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